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chr1:7,686,056-11,137,778

Best TWAS P=8.64e-12 · Best GWAS P=1.96e-11 conditioned to 0.248

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	SLC45A1	0.04	0.05	enet	9	0.02	1.8e-03	-4.6	-5.8	6.2e-09	0.79	0.70	0.22	FALSE
2	GTEx	Adipose Subcutaneous	RERE	0.20	0.23	lasso	2	0.24	1.7e-19	5.1	5.8	6.6e-09	-0.76	0.99	0.01	FALSE
3	GTEx	Adipose Subcutaneous	RP5-1115A15.1	0.14	0.07	enet	20	0.10	2.6e-08	-6.6	6.6	4.6e-11	-0.87	0.01	0.99	FALSE
4	GTEx	Adipose Visceral Omentum	RERE	0.22	0.17	lasso	5	0.17	5.2e-09	-6.7	6.8	8.6e-12	-0.91	0.01	0.99	TRUE
5	GTEx	Brain Caudate basal ganglia	KIF1B	0.25	0.00	lasso	5	0.02	1.1e-01	-5.9	-6.1	1.3e-09	0.00	0.02	0.72	TRUE
6	GTEx	Breast Mammary Tissue	RERE	0.19	0.08	enet	10	0.14	8.0e-08	5.0	6.4	1.2e-10	-0.70	0.21	0.76	FALSE
7	GTEx	Breast Mammary Tissue (Female)	RERE	0.14	0.12	lasso	3	0.08	2.4e-03	-4.8	5.2	2.4e-07	-0.55	0.07	0.55	FALSE
8	GTEx	Cells Transformed fibroblasts	RERE	0.12	0.08	lasso	4	0.05	6.0e-05	5.0	5.3	1.4e-07	-0.66	0.49	0.48	FALSE
9	GTEx	Esophagus Mucosa	RERE	0.13	0.16	lasso	3	0.16	7.2e-11	-6.7	6.7	2.2e-11	-1.00	0.00	1.00	FALSE
10	GTEx	Esophagus Mucosa	RP5-1115A15.1	0.06	0.06	lasso	4	0.05	3.0e-04	-6.7	6.4	1.7e-10	-0.97	0.01	0.97	FALSE
11	GTEx	Lung	RERE	0.07	0.05	lasso	4	0.05	2.0e-04	-6.6	6.7	2.3e-11	-0.87	0.02	0.97	FALSE
12	GTEx	Lung	RP5-1115A15.1	0.05	0.08	lasso	1	0.07	1.0e-05	-6.6	6.6	4.0e-11	-0.98	0.01	0.98	FALSE
13	GTEx	Nerve Tibial	RERE	0.12	0.09	enet	16	0.11	5.6e-08	5.0	5.5	3.4e-08	-0.61	0.96	0.03	FALSE
14	GTEx	Pancreas	RERE	0.11	0.12	lasso	4	0.07	5.9e-04	5.0	5.6	1.9e-08	-0.63	0.11	0.69	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	RERE	0.12	0.05	lasso	4	0.05	1.3e-03	-6.0	5.4	7.1e-08	-0.70	0.07	0.88	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	RP5-1115A15.1	0.08	0.04	enet	8	0.04	3.0e-03	-6.4	6.7	1.9e-11	-0.95	0.02	0.96	FALSE
17	GTEx	Skin Sun Exposed Lower leg	RERE	0.14	0.05	lasso	8	0.08	4.3e-07	-6.7	6.3	2.5e-10	-0.89	0.01	0.99	FALSE
18	GTEx	Skin Sun Exposed Lower leg	RP5-1115A15.1	0.07	0.03	enet	13	0.03	1.5e-03	-6.7	6.4	2.1e-10	-0.87	0.01	0.98	FALSE
19	GTEx	Thyroid	RP5-1115A15.1	0.09	0.12	lasso	2	0.09	1.5e-07	-6.6	6.6	3.3e-11	-0.98	0.01	0.99	FALSE
20	GTEx	Whole Blood	RERE	0.19	0.15	lasso	4	0.13	2.7e-12	-6.7	6.8	1.5e-11	-1.00	0.00	1.00	FALSE
21	METSIM	Adipose	RERE	0.08	0.12	lasso	17	0.13	1.8e-19	5.1	6.6	3.4e-11	-0.80	0.62	0.38	FALSE
22	NTR	Blood	RERE	0.04	0.04	lasso	8	0.03	2.0e-11	-6.4	6.5	6.7e-11	-0.87	0.02	0.98	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	RERE	0.15	0.15	lasso	7	0.15	1.5e-18	4.9	5.4	6.5e-08	-0.71	0.99	0.01	FALSE
24	YFS	Blood	ENO1	0.07	0.06	lasso	7	0.06	5.1e-19	5.2	-5.8	8.2e-09	0.36	0.96	0.04	TRUE
25	YFS	Blood	RERE	0.09	0.15	lasso	4	0.16	5.7e-49	-6.6	6.7	2.3e-11	-0.97	0.01	0.99	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	RERE	0.02	0.03	lasso	2	0.03	4.7e-07	-6.6	6.4	1.2e-10	-0.96	0.01	0.99	FALSE
27	The Cancer Genome Atlas	Esophageal Carcinoma	RERE	0.10	0.07	blup	154	0.06	5.2e-03	-4.9	6.4	2.0e-10	-0.83	0.03	0.64	FALSE
28	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RERE	0.04	0.02	blup	154	0.02	8.7e-04	-6.3	5.9	3.3e-09	-0.82	0.03	0.90	FALSE
29	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RERE	0.22	0.04	lasso	10	0.08	4.1e-04	-6.7	6.3	2.6e-10	-0.89	0.02	0.93	FALSE
30	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	RERE	0.12	0.01	enet	10	0.03	4.6e-02	-5.9	5.6	1.7e-08	-0.81	0.03	0.68	FALSE