[Hub]/) : Traits : Respiratory disease : ← →

chr3:127,097,277-128,821,807

Best TWAS P=4.96e-10 · Best GWAS P=3.91e-09 conditioned to 0.3

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts EEFSEC 0.08 0.08 lasso 2 0.06 2.4e-05 -5.3 5.3 1.2e-07 -0.55 0.14 0.82 FALSE
2 GTEx Cells Transformed fibroblasts RUVBL1 0.07 0.04 lasso 3 0.02 2.5e-02 -5.5 -5.4 5.1e-08 0.98 0.03 0.97 FALSE
3 GTEx Esophagus Muscularis EEFSEC 0.07 0.08 lasso 5 0.07 4.4e-05 -5.5 5.5 4.8e-08 -0.56 0.10 0.86 FALSE
4 GTEx Nerve Tibial EEFSEC 0.07 0.06 lasso 2 0.06 4.5e-05 -5.5 5.4 5.2e-08 -0.55 0.12 0.88 FALSE
5 GTEx Testis RUVBL1 0.31 0.30 lasso 12 0.30 1.2e-13 -5.4 -5.6 2.7e-08 0.98 0.04 0.96 FALSE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma EEFSEC 0.04 0.02 blup 115 0.02 6.7e-03 -5.7 5.1 3.1e-07 -0.98 0.03 0.86 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme EEFSEC 0.09 0.07 lasso 10 0.05 1.7e-02 -5.5 5.8 6.5e-09 -0.98 0.03 0.78 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma EEFSEC 0.07 0.05 blup 115 0.07 1.6e-08 -5.5 5.6 1.7e-08 -0.78 0.10 0.90 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma EEFSEC 0.08 0.03 blup 116 0.04 1.8e-04 -5.5 6.2 5.0e-10 -0.86 0.04 0.96 TRUE