Best TWAS P=1.91e-07 · Best GWAS P=5.43e-07 conditioned to 0.373
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | SRA1 | 0.33 | 0.21 | lasso | 9 | 0.19 | 6.3e-07 | 4.5 | -5.2 | 2.3e-07 | -0.89 | 0.04 | 0.93 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | ZMAT2 | 0.04 | 0.02 | lasso | 4 | 0.02 | 2.4e-02 | -4.7 | -5.2 | 2.3e-07 | -0.72 | 0.08 | 0.78 | FALSE |
| 3 | YFS | Blood | TMCO6 | 0.01 | 0.00 | blup | 329 | 0.01 | 4.1e-03 | -4.5 | -5.1 | 2.9e-07 | -0.81 | 0.15 | 0.79 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC4A9 | 0.07 | 0.02 | blup | 30 | 0.06 | 3.1e-06 | 5.0 | -5.2 | 1.9e-07 | -0.88 | 0.00 | 0.98 | TRUE |