Best TWAS P=3.18e-13 · Best GWAS P=6.31e-14 conditioned to 0.00396
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | NDFIP1 | 0.20 | 0.10 | lasso | 9 | 0.12 | 3.8e-12 | -7.1 | 7.3 | 3.2e-13 | -0.78 | 0.02 | 0.98 | TRUE |
| 2 | METSIM | Adipose | NDFIP1 | 0.23 | 0.15 | lasso | 8 | 0.16 | 7.1e-23 | -5.0 | -6.1 | 1.1e-09 | 0.63 | 1.00 | 0.00 | FALSE |
| 3 | NTR | Blood | NDFIP1 | 0.03 | 0.00 | blup | 610 | 0.01 | 2.9e-03 | -7.5 | -5.9 | 2.8e-09 | 0.66 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NDFIP1 | 0.04 | 0.01 | lasso | 3 | 0.01 | 1.2e-03 | -4.6 | 6.6 | 3.4e-11 | -0.77 | 0.01 | 0.93 | FALSE |