[Hub]/) : Traits : Respiratory disease : ← →

chr5:156,131,251-157,697,754

Best TWAS P=1.47e-09 · Best GWAS P=6.08e-08 conditioned to 0.395

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa ADAM19 0.14 0.03 enet 19 0.09 2.4e-06 -2.8 5.1 2.7e-07 0.65 0.04 0.92 FALSE
2 GTEx Muscle Skeletal ADAM19 0.06 0.02 lasso 4 0.01 1.5e-02 4.8 5.7 1.3e-08 0.70 0.07 0.87 FALSE
3 GTEx Ovary ADAM19 0.32 0.11 lasso 9 0.08 6.5e-03 3.6 5.2 2.4e-07 0.71 0.05 0.69 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic ADAM19 0.10 0.01 lasso 4 0.08 5.2e-05 4.8 6.0 1.5e-09 0.84 0.05 0.93 FALSE
5 GTEx Skin Sun Exposed Lower leg ADAM19 0.07 0.04 lasso 6 0.06 1.2e-05 4.2 5.6 1.8e-08 0.70 0.10 0.86 FALSE
6 GTEx Testis ADAM19 0.16 0.00 enet 17 -0.01 6.7e-01 3.6 5.7 1.2e-08 0.70 0.06 0.71 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADAM19 0.08 0.02 blup 159 0.03 5.3e-04 4.2 5.4 7.4e-08 0.63 0.07 0.52 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma ADAM19 0.09 0.03 lasso 4 0.05 2.4e-06 4.9 6.0 1.5e-09 0.81 0.03 0.96 TRUE
9 The Cancer Genome Atlas Thyroid Carcinoma ADAM19 0.07 0.00 blup 159 0.02 2.0e-03 -2.8 5.1 2.8e-07 0.46 0.14 0.13 FALSE