Best TWAS P=6.31e-13 · Best GWAS P=2.06e-19 conditioned to 0.0024
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | UBAC2 | 0.09 | 0.06 | lasso | 3 | 0.04 | 1.5e-05 | -7.06 | 7.2 | 7.5e-13 | -0.59 | 0.87 | 0.12 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | DOCK9-AS2 | 0.21 | 0.00 | lasso | 5 | -0.01 | 5.2e-01 | -7.32 | -7.2 | 6.3e-13 | 0.51 | 0.07 | 0.05 | TRUE |
| 3 | YFS | Blood | UBAC2 | 0.06 | 0.03 | bslmm | 612 | 0.05 | 2.1e-15 | 4.40 | -6.5 | 1.0e-10 | 0.56 | 0.98 | 0.02 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | UBAC2 | 0.05 | 0.00 | blup | 118 | 0.02 | 2.8e-04 | 0.62 | -7.0 | 3.1e-12 | 0.49 | 0.15 | 0.18 | TRUE |