[Hub]/) : Traits : Respiratory disease : ← →

chr12:55,601,472-58,677,299

Best TWAS P=2.79e-19 · Best GWAS P=1.26e-26 conditioned to 0.00262

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RPS26	0.48	0.62	lasso	5	0.63	5.9e-99	8.561	8.7	3.3e-18	-0.01	0.12	0.88	FALSE
2	GTEx	Artery Aorta	SUOX	0.36	0.30	lasso	7	0.35	3.8e-20	8.379	-8.2	1.7e-16	0.00	0.32	0.68	FALSE
3	GTEx	Artery Aorta	STAT6	0.12	0.07	enet	22	0.05	1.1e-03	9.828	6.6	3.9e-11	0.42	0.38	0.28	FALSE
4	GTEx	Artery Tibial	LRP1	0.15	0.12	lasso	2	0.10	3.9e-08	5.910	-5.6	2.1e-08	-0.58	0.99	0.00	FALSE
5	GTEx	Artery Tibial	SUOX	0.18	0.14	enet	23	0.18	2.1e-14	8.407	-7.5	6.5e-14	0.00	0.29	0.71	FALSE
6	GTEx	Artery Tibial	STAT6	0.08	0.03	enet	4	0.02	1.3e-02	5.810	8.3	8.5e-17	0.85	0.06	0.80	FALSE
7	GTEx	Artery Tibial	RPS26	0.07	0.02	enet	5	0.01	3.5e-02	8.561	8.2	2.8e-16	0.00	0.06	0.79	FALSE
8	GTEx	Brain Cerebellum	SUOX	0.24	0.20	lasso	6	0.20	1.2e-06	8.379	-7.7	9.5e-15	0.02	0.22	0.63	FALSE
9	GTEx	Brain Cortex	SUOX	0.16	0.11	lasso	4	0.10	1.1e-03	8.379	-8.3	1.3e-16	0.02	0.04	0.59	FALSE
10	GTEx	Brain Nucleus accumbens basal ganglia	SUOX	0.18	0.08	lasso	4	0.10	1.1e-03	8.379	-7.3	3.6e-13	0.03	0.06	0.44	FALSE
11	GTEx	Breast Mammary Tissue	RPS26	0.29	0.05	enet	37	0.12	9.4e-07	8.561	6.7	1.8e-11	-0.04	0.20	0.79	FALSE
12	GTEx	Breast Mammary Tissue (Female)	RPS26	0.20	0.11	lasso	3	0.10	6.6e-04	8.379	7.8	8.2e-15	-0.03	0.05	0.20	FALSE
13	GTEx	Cells Transformed fibroblasts	RPS26	0.11	0.08	enet	15	0.09	3.4e-07	7.756	7.9	3.1e-15	-0.02	0.34	0.66	FALSE
14	GTEx	Colon Sigmoid	SUOX	0.23	0.18	lasso	4	0.15	7.9e-06	8.379	-8.6	1.0e-17	0.01	0.09	0.90	FALSE
15	GTEx	Colon Transverse	SUOX	0.24	0.22	enet	24	0.25	3.8e-12	8.379	-6.4	1.5e-10	0.04	0.34	0.66	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	SUOX	0.20	0.16	lasso	5	0.19	2.7e-07	8.407	-8.4	6.6e-17	0.01	0.09	0.90	FALSE
17	GTEx	Esophagus Gastroesophageal Junction	WIBG	0.16	0.02	lasso	5	0.04	1.9e-02	0.084	-6.2	7.5e-10	-0.01	0.02	0.72	FALSE
18	GTEx	Esophagus Muscularis	SUOX	0.24	0.19	enet	16	0.15	2.3e-09	8.379	-8.4	6.2e-17	0.02	0.36	0.64	FALSE
19	GTEx	Esophagus Muscularis	RPS26	0.19	0.06	enet	46	0.05	9.3e-04	8.561	6.5	9.5e-11	0.01	0.10	0.39	FALSE
20	GTEx	Heart Atrial Appendage	SUOX	0.09	0.10	enet	8	0.09	1.1e-04	8.561	-8.1	4.4e-16	0.00	0.08	0.79	FALSE
21	GTEx	Lung	SUOX	0.34	0.23	enet	38	0.26	4.6e-20	8.379	-6.5	6.9e-11	0.04	0.37	0.63	FALSE
22	GTEx	Muscle Skeletal	RAB5B	0.29	0.32	lasso	4	0.33	1.3e-33	8.472	-8.6	8.4e-18	0.00	0.16	0.84	FALSE
23	GTEx	Muscle Skeletal	SUOX	0.11	0.04	lasso	7	0.04	4.4e-05	8.379	-7.4	1.3e-13	0.00	0.24	0.70	FALSE
24	GTEx	Muscle Skeletal	AC034102.1	0.28	0.31	lasso	4	0.31	2.3e-31	8.551	-8.6	8.1e-18	0.00	0.15	0.85	FALSE
25	GTEx	Nerve Tibial	SUOX	0.34	0.30	enet	22	0.35	8.5e-26	8.379	-7.5	5.5e-14	-0.01	0.36	0.64	FALSE
26	GTEx	Nerve Tibial	RPS26	0.12	0.09	enet	7	0.11	3.0e-08	7.134	7.2	4.5e-13	0.00	0.38	0.61	FALSE
27	GTEx	Ovary	SUOX	0.23	0.14	enet	12	0.21	8.4e-06	8.407	-7.7	1.6e-14	0.03	0.10	0.37	FALSE
28	GTEx	Ovary	RPS26	0.50	0.24	enet	25	0.22	5.0e-06	7.629	6.9	5.9e-12	-0.02	0.25	0.68	FALSE
29	GTEx	Pancreas	SUOX	0.30	0.20	enet	23	0.30	3.5e-13	8.407	-7.0	3.3e-12	0.04	0.32	0.67	FALSE
30	GTEx	Pituitary	SUOX	0.44	0.13	enet	20	0.27	1.4e-07	7.756	-5.4	7.5e-08	0.01	0.11	0.32	FALSE
31	GTEx	Prostate	SUOX	0.22	0.04	enet	11	0.05	2.3e-02	8.407	-8.4	5.3e-17	0.01	0.04	0.72	FALSE
32	GTEx	Skin Not Sun Exposed Suprapubic	SUOX	0.10	0.14	lasso	2	0.12	2.5e-07	8.379	-8.4	3.1e-17	0.02	0.17	0.81	FALSE
33	GTEx	Skin Not Sun Exposed Suprapubic	KIF5A	0.13	0.00	enet	9	0.03	6.7e-03	4.064	6.2	5.8e-10	0.38	0.10	0.72	TRUE
34	GTEx	Skin Sun Exposed Lower leg	SUOX	0.23	0.30	lasso	3	0.29	1.9e-24	8.379	-8.6	1.1e-17	0.02	0.39	0.61	FALSE
35	GTEx	Spleen	SUOX	0.34	0.31	enet	15	0.28	5.4e-08	8.379	-7.6	2.7e-14	0.05	0.19	0.65	FALSE
36	GTEx	Stomach	SUOX	0.15	0.17	enet	8	0.09	6.7e-05	8.379	-8.3	1.2e-16	0.02	0.33	0.63	FALSE
37	GTEx	Stomach	RPS26	0.16	0.08	enet	5	0.05	1.8e-03	8.379	7.9	3.0e-15	0.01	0.10	0.46	FALSE
38	GTEx	Testis	SUOX	0.27	0.18	lasso	14	0.18	1.4e-08	8.379	-8.2	1.6e-16	0.00	0.09	0.91	FALSE
39	GTEx	Thyroid	SUOX	0.37	0.40	lasso	7	0.38	5.4e-31	8.379	-8.3	9.4e-17	0.02	0.39	0.61	FALSE
40	GTEx	Whole Blood	SUOX	0.07	0.01	enet	20	0.02	1.1e-02	8.561	-7.2	5.3e-13	0.00	0.01	0.97	FALSE
41	GTEx	Whole Blood	RPS26	0.05	0.05	lasso	1	0.05	3.4e-05	8.407	8.4	4.2e-17	-0.02	0.04	0.94	FALSE
42	METSIM	Adipose	IKZF4	0.04	0.04	enet	3	0.04	1.0e-06	7.629	7.8	4.8e-15	0.00	0.49	0.51	FALSE
43	METSIM	Adipose	RPS26	0.30	0.40	lasso	5	0.41	7.2e-66	7.756	8.2	3.1e-16	0.00	0.24	0.76	FALSE
44	METSIM	Adipose	SUOX	0.04	0.01	blup	288	0.02	1.1e-03	7.629	-5.4	7.7e-08	-0.03	0.51	0.29	FALSE
45	YFS	Blood	STAT6	0.74	0.58	enet	50	0.73	0.0e+00	-4.880	-5.4	8.6e-08	-0.61	1.00	0.00	FALSE
46	YFS	Blood	SUOX	0.11	0.09	bslmm	269	0.09	3.4e-27	8.407	-7.6	2.7e-14	0.03	0.35	0.65	FALSE
47	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RPS26	0.14	0.22	lasso	2	0.23	4.8e-19	7.756	8.0	9.1e-16	0.00	0.38	0.62	FALSE
48	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPS26	0.30	0.44	enet	10	0.45	5.2e-104	8.561	8.6	9.2e-18	0.00	0.10	0.90	FALSE
49	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RPS26	0.23	0.40	lasso	2	0.39	1.5e-20	8.561	8.8	1.9e-18	0.00	0.09	0.91	FALSE
50	The Cancer Genome Atlas	Colon Adenocarcinoma	RPS26	0.43	0.48	lasso	4	0.47	1.8e-30	8.561	8.8	1.3e-18	0.00	0.10	0.90	FALSE
51	The Cancer Genome Atlas	Esophageal Carcinoma	RPS26	0.19	0.13	lasso	5	0.11	2.4e-04	8.561	8.8	2.0e-18	0.00	0.01	0.98	FALSE
52	The Cancer Genome Atlas	Glioblastoma Multiforme	RPS26	0.41	0.38	enet	9	0.39	7.9e-13	7.756	8.1	5.2e-16	0.00	0.23	0.77	FALSE
53	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RPS26	0.17	0.29	lasso	4	0.29	6.2e-33	7.756	8.2	3.3e-16	0.00	0.38	0.62	FALSE
54	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GPR182	0.07	0.00	lasso	2	0.00	8.8e-02	-6.985	-7.3	2.3e-13	-0.21	0.00	0.89	TRUE
55	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RPS26	0.50	0.45	enet	13	0.52	1.4e-67	7.756	7.5	5.0e-14	0.00	0.67	0.33	FALSE
56	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RPS26	0.27	0.38	enet	8	0.40	5.0e-24	8.561	8.7	3.5e-18	-0.01	0.12	0.88	FALSE
57	The Cancer Genome Atlas	Brain Lower Grade Glioma	ERBB3	0.07	0.02	blup	29	0.05	2.1e-06	8.999	6.5	8.9e-11	0.02	0.00	1.00	FALSE
58	The Cancer Genome Atlas	Brain Lower Grade Glioma	RPS26	0.31	0.53	enet	8	0.55	1.7e-74	8.561	8.4	6.3e-17	0.00	0.17	0.83	FALSE
59	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RPS26	0.18	0.31	lasso	2	0.29	3.9e-14	8.561	8.5	1.5e-17	-0.01	0.12	0.88	FALSE
60	The Cancer Genome Atlas	Lung Adenocarcinoma	RAB5B	0.03	0.02	enet	7	0.02	4.3e-03	8.472	7.3	2.2e-13	-0.01	0.02	0.53	FALSE
61	The Cancer Genome Atlas	Lung Adenocarcinoma	RPS26	0.26	0.45	enet	9	0.47	3.6e-61	8.561	8.6	1.2e-17	0.00	0.14	0.86	FALSE
62	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RPS26	0.22	0.31	lasso	3	0.31	1.6e-35	8.561	8.8	1.5e-18	0.00	0.10	0.90	FALSE
63	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPS26	0.30	0.20	lasso	4	0.24	3.9e-16	8.561	8.9	4.4e-19	0.00	0.03	0.97	TRUE
64	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RPS26	0.36	0.44	lasso	7	0.42	2.4e-19	7.756	8.1	7.6e-16	0.00	0.38	0.62	FALSE
65	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RPS26	0.47	0.43	lasso	2	0.44	3.2e-19	8.407	8.6	8.8e-18	-0.01	0.18	0.82	FALSE
66	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPS26	0.33	0.52	enet	9	0.54	5.6e-66	8.561	8.6	1.0e-17	0.00	0.11	0.89	FALSE
67	The Cancer Genome Atlas	Prostate Adenocarcinoma	SDR9C7	0.12	0.04	lasso	2	0.04	2.9e-05	-6.618	-7.2	5.2e-13	-0.10	0.05	0.86	FALSE
68	The Cancer Genome Atlas	Rectum Adenocarcinoma	RPS26	0.24	0.18	lasso	2	0.20	1.9e-05	8.561	8.6	6.2e-18	-0.01	0.04	0.63	FALSE
69	The Cancer Genome Atlas	Soft Tissue Sarcoma	RPS26	0.23	0.31	lasso	3	0.30	2.4e-18	8.561	8.7	4.5e-18	0.00	0.10	0.90	FALSE
70	The Cancer Genome Atlas	Skin Cutaneous Melanoma	RPS26	0.28	0.15	lasso	2	0.17	3.0e-05	8.594	8.8	1.2e-18	-0.01	0.01	0.95	FALSE
71	The Cancer Genome Atlas	Stomach Adenocarcinoma	ERBB3	0.13	0.01	enet	12	0.03	1.9e-03	7.756	-5.7	1.3e-08	0.07	0.01	0.28	FALSE
72	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPS26	0.19	0.32	lasso	5	0.34	2.0e-25	7.756	8.3	1.3e-16	0.00	0.37	0.63	FALSE
73	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RPS26	0.46	0.64	lasso	4	0.65	8.5e-30	8.561	8.7	4.3e-18	0.00	0.16	0.84	FALSE
74	The Cancer Genome Atlas	Thyroid Carcinoma	RPS26	0.33	0.51	enet	19	0.50	7.3e-56	8.561	8.3	1.5e-16	-0.01	0.10	0.90	FALSE
75	The Cancer Genome Atlas	Thyroid Carcinoma	STAT6	0.04	0.01	blup	47	0.01	2.3e-02	8.589	9.0	2.8e-19	0.74	0.04	0.57	TRUE
76	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM194A	0.15	0.07	blup	43	0.09	1.9e-09	5.319	6.5	9.6e-11	0.37	0.39	0.50	FALSE
77	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	RPS26	0.17	0.19	lasso	4	0.18	1.3e-05	8.561	8.7	4.2e-18	-0.01	0.02	0.97	FALSE