Best TWAS P=6.18e-08 · Best GWAS P=4.16e-08 conditioned to 0.171
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Male) | OIP5-AS1 | 0.26 | 0.10 | enet | 20 | 0.22 | 7.3e-06 | 4.1 | 5.3 | 1.4e-07 | -0.63 | 0.16 | 0.52 | FALSE |
2 | GTEx | Thyroid | RTF1 | 0.28 | 0.27 | lasso | 3 | 0.26 | 8.4e-20 | -5.1 | -5.1 | 2.8e-07 | 0.91 | 0.01 | 0.99 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | RTF1 | 0.04 | 0.02 | lasso | 3 | 0.02 | 4.0e-03 | -5.1 | -5.4 | 6.2e-08 | 0.91 | 0.00 | 0.97 | TRUE |