[Hub]/) : Traits : Reaction Time :

chr2:174,136,944-176,043,097

Best TWAS P=6.66e-10 · Best GWAS P=5.65e-10 conditioned to 0.0348

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex OLA1 0.22 0.24 enet 22 0.25 2.8e-30 5.1 6.2 6.7e-10 0.80 0.48 0.52 TRUE
2 GTEx Skin Sun Exposed Lower leg RP11-394I13.2 0.08 0.01 lasso 3 0.01 1.0e-01 5.7 -5.9 4.2e-09 -0.79 0.01 0.91 FALSE
3 METSIM Adipose CIR1 0.05 0.02 lasso 4 0.02 1.5e-03 4.2 5.7 1.1e-08 0.71 0.05 0.90 FALSE
4 ROSMAP Brain Pre-frontal Cortex OLA1 0.11 0.07 lasso 5 0.06 1.4e-08 5.5 -6.1 1.3e-09 -0.92 0.01 0.99 FALSE
5 ROSMAP Brain Pre-frontal Cortex GPR155 0.21 0.16 lasso 7 0.19 1.3e-23 4.2 -5.2 2.1e-07 -0.43 0.98 0.01 FALSE
6 YFS Blood OLA1 0.01 0.00 lasso 2 0.00 1.5e-01 4.9 5.2 2.0e-07 0.67 0.10 0.10 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme OLA1 0.12 0.13 lasso 2 0.09 1.4e-03 5.3 5.3 1.4e-07 0.53 0.13 0.42 FALSE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors OLA1 0.13 0.10 lasso 3 0.08 1.0e-03 6.0 6.0 1.5e-09 0.80 0.01 0.86 FALSE