Hub : Genes

OLA1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2190 0.0370 0.0e+00 0.237 0.165 0.251 0.220 0.218 1.7e-28 1.2e-19 2.8e-30 2.4e-26 4.3e-26
2 NTR Blood 0.0364 0.0122 7.6e-05 0.022 0.020 0.021 0.020 0.020 6.4e-08 2.5e-07 1.6e-07 2.4e-07 2.9e-07
3 ROSMAP Brain Pre-frontal Cortex 0.1105 0.0286 7.5e-09 0.068 0.051 0.062 0.052 0.064 4.4e-09 3.2e-07 1.9e-08 2.5e-07 1.3e-08
4 YFS Blood 0.0105 0.0060 3.1e-02 -0.001 0.000 -0.001 0.000 0.001 7.6e-01 4.5e-01 5.9e-01 3.0e-01 1.5e-01
5 TCGA Glioblastoma Multiforme 0.1210 0.0660 2.2e-03 0.134 0.051 0.022 NA 0.086 7.2e-05 1.2e-02 7.0e-02 NA 1.4e-03
6 TCGA Brain Lower Grade Glioma 0.0594 0.0239 3.5e-07 0.054 0.048 0.059 NA 0.064 9.7e-07 3.8e-06 2.5e-07 NA 8.6e-08
7 TCGA Ovarian Serous Cystadenocarcinoma 0.0700 0.0360 1.7e-03 0.076 0.045 0.049 NA 0.070 7.8e-06 5.1e-04 2.9e-04 NA 1.8e-05
8 TCGA Prostate Adenocarcinoma 0.0504 0.0290 2.6e-04 0.023 0.037 0.023 NA 0.023 1.6e-03 7.8e-05 1.7e-03 NA 1.7e-03
9 TCGA Testicular Germ Cell Tumors 0.1330 0.0720 9.0e-03 0.098 0.036 0.058 NA 0.078 2.6e-04 2.1e-02 4.1e-03 NA 1.0e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 2.1 3.3 5.0 2.2 1.8 -1.9 2.0 2.0 1.3 0.6 1.9 2.0
Bipolar Disorder or Schizophrenia 4.8 11.8 17.1 4.1 3.3 -4.1 3.7 4.0 2.6 0.6 2.9 4.0
Depressed Affect (Nagel 2018) 0.7 1.4 2.9 1.1 1.3 -0.6 1.4 1.7 1.3 0.5 1.5 0.8
Depression (Nagel 2018) 1.8 2.8 6.4 1.9 1.9 -1.4 1.6 2.5 1.9 1.3 1.2 0.5
Intelligence (Savage-Jansen 2018) 0.2 0.5 1.7 -0.6 -0.5 0.8 -0.2 -0.9 -0.4 -0.1 -0.6 -1.3
Neuroticism (Nagel 2018) 0.6 1.3 4.2 0.8 0.2 -0.6 1.1 1.6 0.5 -0.5 1.5 2.0
Schizophrenia (2018) 4.2 8.8 14.1 3.5 2.8 -3.8 3.1 3.5 2.3 0.3 2.2 3.6
Schizophrenia vs Biploar Disorder 0.5 0.6 2.3 -1.0 -0.3 1.5 0.0 -0.7 -0.8 0.2 -0.4 -1.0
Worry (Nagel 2018) 0.3 0.6 2.9 0.1 -0.5 -0.1 0.0 1.1 -0.5 -0.6 0.5 1.7
Alzheimer’s Disease (in mother) 0.5 0.6 1.7 0.5 0.9 0.2 1.3 0.6 0.5 1.2 0.7 -0.4
Alzheimer’s Disease (in father) 0.1 0.1 0.5 -0.1 -0.2 0.3 0.2 0.1 -0.1 0.4 0.0 -0.7
Alzheimer’s Disease (including proxy) 0.7 1.0 2.4 0.9 1.6 -0.2 1.0 0.7 1.1 1.4 0.7 -0.7
Crohns Disease (2017) 0.4 1.0 2.9 -1.0 -0.0 1.6 -0.9 -0.1 -0.1 1.7 -0.3 -1.2
Irritable Bowel Disease (IBD) 0.3 0.7 2.0 -1.0 -0.4 1.4 -1.1 -0.1 0.0 0.8 -0.6 -0.8
Ulcerative Colitis (UC) 0.2 0.3 0.9 -0.6 -0.5 0.7 -0.9 -0.3 0.1 -0.2 -0.6 -0.3
Major Depression (MDD) 1.3 1.6 4.8 0.8 1.7 0.4 0.7 1.5 1.2 2.2 0.8 -1.0
Reaction Time 13.4 25.5 38.1 6.2 4.5 -6.1 5.2 5.3 5.0 0.0 4.3 6.0
Verbal and Numeric Reasoning (VNR) 0.1 0.2 0.6 0.5 0.2 -0.8 0.2 -0.2 0.7 -0.6 -0.6 -0.1
Breast Cancer 0.5 1.3 5.2 -0.5 -1.2 -0.8 -0.2 -1.2 -1.1 -2.3 -0.8 0.9
Ovarian Cancer 0.8 1.1 2.5 0.8 0.2 -1.5 1.2 0.8 1.1 -0.9 0.5 1.6
Prostate Cancer 0.2 0.3 0.8 0.5 0.4 -0.5 0.5 0.6 0.2 -0.3 0.4 0.9
Age at First Birth 0.1 0.2 0.6 0.4 0.3 -0.3 0.8 0.1 -0.2 -0.4 0.6 0.2
Bipolar Disorder (2011) 2.8 2.7 4.9 2.1 2.2 -2.2 0.6 1.8 1.3 0.0 0.8 2.0
Body Mass Index (BMI) (2010) 1.3 1.8 3.8 1.6 1.6 -0.5 1.8 1.2 1.2 1.2 2.0 0.1
Coronary Artery Disease (CAD) 0.1 0.1 0.4 -0.1 0.2 0.2 -0.2 0.1 0.4 0.4 -0.7 -0.1
Crohns Disease (2012) 0.5 0.8 2.5 -0.8 0.0 1.3 -1.1 0.1 0.0 1.6 -0.4 -0.9
Mean Putamen Volume 0.2 0.2 0.7 -0.1 -0.6 0.2 0.1 -0.6 0.0 -0.1 -0.5 -0.8
Fasting Glucose 2.0 2.4 4.2 1.8 2.1 -0.7 0.8 2.0 1.9 0.9 1.7 1.3
HbA1C 0.5 0.6 1.6 -0.3 -1.2 -0.6 -1.1 0.0 -0.3 -0.7 -1.3 0.2
HDL Cholesterol 0.1 0.2 0.7 -0.3 0.3 0.8 -0.2 -0.4 0.0 0.5 0.4 -0.8
LDL Cholesterol 1.5 2.3 4.8 -1.9 -0.7 1.8 -1.6 -1.3 -1.2 0.8 -1.5 -2.2
Lupus 0.4 0.6 2.7 0.5 0.3 -0.8 -0.9 -0.3 0.7 -0.4 -1.6 -0.2
Neuroticism (2016) 0.7 1.0 1.9 -1.2 -1.1 0.6 -0.4 -1.4 -1.3 -1.2 -0.9 0.3
Primary Biliary Cirrhosis 2.2 3.1 5.7 2.0 1.7 -1.1 1.5 2.3 2.4 1.9 1.7 0.7
Rheumatoid Arthritis 0.1 0.1 0.2 -0.3 -0.2 0.5 -0.2 -0.1 0.0 0.4 0.1 -0.3
Schizophrenia (2014) 1.5 3.2 5.5 2.0 1.6 -1.8 2.3 2.4 1.1 0.5 1.7 1.9
Triglycerides 0.0 0.1 0.2 0.3 0.3 -0.3 0.2 0.4 -0.0 0.2 -0.1 0.1
Type 2 Diabetes (T2D) (2012) 0.3 0.3 1.6 0.4 0.8 -0.5 -0.0 0.3 0.3 1.3 -0.3 -0.3
Ulcerative Colitis 0.1 0.2 0.5 0.2 -0.1 0.3 0.0 0.7 0.7 0.2 0.4 0.7
Blood Eosinophil Count 0.1 0.9 2.3 -0.7 -1.2 0.2 -0.8 -0.7 -1.5 -1.4 -0.4 1.0
Blood Platelet Count 0.5 6.0 10.2 3.2 2.4 -2.0 2.0 3.1 2.3 1.2 2.3 2.9
Blood Red Count 0.5 4.7 12.7 2.1 2.6 0.0 1.9 2.1 2.4 3.6 2.1 -0.5
Blood White Count 0.0 0.3 1.6 0.4 0.6 0.0 0.4 0.2 -0.3 0.3 0.4 1.3
Heel T-Score 0.3 2.0 7.3 0.2 -0.5 -2.2 0.5 -0.8 -0.7 -2.7 -1.3 1.5
BMI 5.4 31.3 56.7 7.0 7.5 -4.6 5.2 5.6 6.9 4.2 5.1 2.5
Height 0.2 4.6 18.7 -2.1 0.2 4.3 -1.8 -1.4 -1.4 1.8 0.8 -2.8
Waist Hip Ratio (WHR) 0.1 0.6 1.9 0.2 1.4 0.4 -1.0 -0.4 0.2 0.4 -1.0 -0.8
Systolic Blood Pressure 4.8 24.3 35.4 6.0 4.0 -4.9 5.7 5.9 5.4 3.0 4.4 4.3
Smoking Status 5.5 13.1 25.9 -4.4 -4.0 3.1 -3.1 -4.0 -5.1 -2.9 -2.9 -2.0
Allergy or Eczema 0.1 0.3 0.9 0.6 0.0 -0.3 0.9 0.3 0.5 0.4 0.9 -0.3
Cardiovascular Disease 5.2 17.3 28.1 5.3 3.7 -4.8 4.7 4.7 4.4 2.1 3.4 3.2
Hypothyroidism (self reported) 1.3 3.1 5.6 2.2 2.1 -1.4 2.0 1.5 2.4 1.7 1.4 0.3
Respiratory disease 0.3 0.6 3.1 0.7 1.8 0.2 0.3 0.7 0.7 0.6 0.9 0.1
Type 2 Diabetes (T2D) (2018) 1.0 1.9 3.2 1.6 0.9 -1.7 1.5 1.4 1.3 -0.2 1.1 1.8
Lung FEV1/FVC ratio 0.3 1.7 4.2 1.0 1.8 0.0 1.0 0.5 1.4 2.1 -0.2 -1.9
Lung FVC 0.8 4.2 12.7 1.0 -0.4 -3.2 1.4 0.1 -0.3 -3.6 0.8 3.3
Neuroticism 0.8 2.0 6.0 1.3 0.7 -1.0 1.3 2.0 0.6 -0.1 1.7 2.5
Chronotype (morning person) 1.0 2.2 7.1 -1.3 -0.3 2.7 -1.2 -0.5 -0.3 2.2 -0.2 -2.1
Hair Pigment 0.1 3.2 13.5 0.4 -0.7 -1.7 -0.6 0.7 -0.9 -3.2 0.5 3.7
Tanning 0.2 2.6 4.7 -1.4 -2.0 0.2 -1.7 -1.9 -1.9 -2.2 -1.6 -0.2
Hand grip strength (left) 2.4 6.2 10.2 -2.3 -3.0 0.9 -3.0 -2.5 -3.2 -2.9 -2.6 -0.5
Number of treatments/medications taken 2.8 5.0 8.2 2.9 1.6 -2.9 2.6 2.3 2.3 0.3 1.8 2.3
Average weekly spirits intake 0.3 0.3 1.3 0.7 1.1 -0.4 -0.3 0.3 0.6 0.7 0.1 0.0
Sensitivity / hurt feelings 0.2 0.4 1.0 -0.6 -0.5 0.5 0.4 -0.3 -1.0 -1.0 0.3 0.8
Frequency of depressed mood in last 2 weeks 0.1 0.1 0.4 0.1 0.3 -0.2 0.2 0.7 0.1 0.2 -0.2 0.2
Hearing difficulty/problems: Yes 0.1 0.1 0.4 -0.1 0.1 -0.2 0.0 -0.5 0.0 -0.4 -0.6 0.1
Relative age of first facial hair 2.0 4.1 18.7 1.3 -0.8 -2.1 -0.2 2.7 0.5 -1.5 1.4 4.3
Other serious medical condition/disability diagnosed by doctor 5.5 7.1 12.2 3.3 3.5 -2.5 2.2 2.7 3.4 2.8 1.7 0.6
Ever used hormone-replacement therapy (HRT) 1.5 2.0 3.3 -1.6 -1.3 1.8 -1.2 -1.3 -1.5 0.2 -1.3 -1.6
Ever had hysterectomy (womb removed) 0.5 0.6 1.9 0.7 -0.6 -1.4 0.4 0.6 1.1 0.0 0.4 0.5
Systolic blood pressure, automated reading 6.5 18.8 26.1 4.9 4.1 -3.1 5.1 5.0 5.0 3.4 4.7 2.9
Eye problems/disorders: Diabetes related eye disease 1.0 1.1 3.3 0.2 0.2 0.9 0.8 -0.0 0.6 1.6 1.2 -1.8
Angina 1.2 1.6 4.6 0.6 1.5 -0.3 0.3 -0.5 1.3 1.6 -1.6 -2.2
Medication for hormone replacement therapy 0.5 0.6 1.9 -0.6 -0.7 0.3 -1.4 -0.6 -0.5 -0.6 -1.2 -0.1
Vitamin and mineral supplements 1.1 1.5 4.2 -1.2 -0.7 1.6 -1.0 -1.1 -1.0 1.1 -0.5 -2.1
Supplements: Zinc 1.2 1.3 2.8 1.2 0.3 -1.7 1.6 1.4 0.7 -0.4 0.6 1.3
Medication: Co-codamol 7.0 8.1 17.6 3.2 4.2 -1.6 2.2 2.9 3.5 2.6 3.0 0.6
Medication: Metformin 2.2 3.1 5.1 2.0 1.6 -1.2 2.3 1.9 2.2 1.3 2.0 0.6
Diabetes (father) 1.4 1.7 3.8 1.2 2.0 -0.8 1.6 1.3 1.4 1.2 1.5 -0.2
Diabetes (mother) 0.3 0.4 0.8 0.8 0.7 -0.4 0.0 0.7 0.9 0.9 0.1 -0.4
Severe depression (siblings) 0.2 0.3 0.6 -0.5 -0.3 0.5 0.8 -0.3 -0.6 0.1 -0.5 -0.7
Pack years adult smoking proportion 0.4 0.6 1.7 -0.6 0.6 0.7 -0.3 -0.3 0.3 1.0 -0.9 -1.3
Impedance of leg (right) 0.8 4.0 6.4 -2.5 -2.1 1.7 -1.4 -2.3 -2.2 -1.6 -2.5 -1.1
Leg fat-free mass (left) 2.4 12.8 22.2 4.0 4.7 -1.6 2.9 3.8 4.0 3.6 4.6 1.2
Trunk fat percentage 3.3 13.3 25.5 4.1 5.0 -2.1 4.8 2.7 4.7 3.2 3.1 0.5
Hand grip strength (right) 1.5 4.1 8.2 -1.6 -2.0 0.2 -2.6 -1.9 -2.8 -2.9 -1.9 0.3
Townsend deprivation index at recruitment 0.5 0.6 3.4 0.4 1.9 0.1 0.9 -0.2 0.3 0.9 0.3 -0.5
Current tobacco smoking 0.9 1.5 2.7 -1.6 -0.3 1.3 -1.7 -1.0 -1.6 -0.0 -1.6 -1.0
Average weekly fortified wine intake 1.1 1.3 3.8 -1.3 -0.5 1.0 -0.7 -1.7 -0.8 -0.2 -1.1 -2.0
Maternal smoking around birth 4.0 5.8 10.2 -3.0 -2.5 2.2 -2.1 -2.6 -3.2 -1.4 -2.6 -1.6
Fed-up feelings 0.4 0.8 1.8 0.4 1.0 0.7 0.9 0.9 0.6 1.1 1.3 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 1.9 0.9 1.4 -0.5 0.8 1.2 1.1 0.9 0.3 0.3
Relative age voice broke 0.5 0.7 2.7 -0.3 -0.9 0.5 -1.6 1.1 -0.2 0.4 0.2 1.1
Taking other prescription medications 3.7 5.8 10.1 2.8 2.4 -1.9 3.2 2.7 2.6 1.8 2.3 1.5
Age when periods started (menarche) 0.6 1.5 2.9 -1.7 -0.9 1.6 -1.6 -1.2 -1.5 -0.7 -0.4 -0.7
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 0.9 0.8 0.5 -0.6 0.4 0.5 0.9 0.9 0.4 0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.9 2.0 3.9 -1.9 -1.4 0.9 -0.8 -1.6 -2.0 -1.7 -1.2 -0.5
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 0.8 0.2 0.2 -0.2 0.2 0.9 0.9 0.7 0.4 -0.3
Qualifications: CSEs or equivalent 0.2 0.2 0.5 -0.6 -0.6 0.7 -0.6 -0.2 -0.7 -0.4 0.1 0.1
Serious illness, injury or assault to yourself 2.6 3.1 6.1 1.9 2.5 -1.1 1.1 2.4 1.5 1.2 1.9 1.7
High blood pressure 5.1 14.1 22.6 4.8 3.4 -4.1 4.2 4.3 4.2 2.4 3.5 2.3
Hayfever, allergic rhinitis or eczema 0.2 0.4 2.1 0.4 -0.2 0.2 0.8 0.4 0.3 0.1 1.4 -0.1
Multivitamins +/- minerals 0.5 0.7 1.2 0.9 0.9 -0.8 1.1 0.9 0.9 -0.3 0.3 1.1
Stomach or abdominal pain in last month 1.8 2.2 6.1 1.5 2.4 -0.5 1.2 1.1 1.4 2.5 1.1 -0.5
Supplements: Glucosamine 0.6 0.8 2.6 1.0 0.5 -1.6 -0.0 0.8 0.9 -0.2 -0.4 1.1
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 2.4 0.9 0.3 -0.8 0.0 1.2 0.5 0.3 0.2 1.6
Medication: Atenolol 0.7 0.9 2.4 1.2 0.7 -1.6 0.8 0.4 1.2 -0.6 -0.7 0.4
Medication: Levothyroxine sodium 1.1 1.9 3.3 1.4 1.4 -0.8 1.3 1.8 1.6 1.7 1.4 0.5
Sitting height 0.4 2.6 8.6 -0.1 1.9 2.2 -1.3 0.6 0.8 2.9 0.7 -1.7
Chronic bronchitis/emphysema (father) 0.6 0.7 2.2 0.8 0.9 -1.1 -0.2 1.2 0.4 0.0 0.4 1.5
High blood pressure (mother) 0.4 0.6 1.9 0.7 0.7 -0.2 0.7 0.6 0.9 1.4 0.8 -0.5
Body mass index (BMI) 5.2 22.2 37.2 5.6 6.1 -3.3 4.8 4.6 5.9 4.3 4.7 1.4
Impedance of leg (left) 1.3 6.5 9.5 -3.1 -3.0 1.9 -2.0 -2.9 -3.0 -2.3 -3.1 -1.1
Leg predicted mass (left) 2.5 13.1 22.3 4.0 4.7 -1.6 3.0 3.9 4.1 3.6 4.7 1.2
Trunk fat mass 3.8 16.5 33.1 4.5 5.8 -2.0 4.6 3.5 5.1 4.0 4.0 0.6
Waist circumference 5.0 18.2 36.2 4.9 6.0 -2.4 3.9 4.0 5.4 4.6 4.0 0.8
Number of incorrect matches in round 0.7 1.1 2.2 -1.1 -1.4 1.5 0.3 -1.1 -1.4 -0.1 0.4 -0.8
Past tobacco smoking 5.9 10.9 16.6 4.0 3.6 -3.2 2.9 4.1 4.0 2.1 2.4 2.8
Alcohol usually taken with meals 1.0 1.6 6.2 -0.9 -0.1 1.1 0.2 -1.8 -0.5 0.0 -1.6 -2.5
Nervous feelings 0.2 0.5 2.1 -0.6 -0.0 1.4 0.3 -0.0 -0.1 1.0 0.5 -0.6
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 1.2 0.6 1.1 -0.3 0.5 0.8 0.7 0.7 0.4 0.3
Hearing difficulty/problems with background noise 0.1 0.1 0.4 0.2 0.6 -0.2 0.2 -0.1 0.6 0.5 -0.3 -0.2
Hair/balding pattern: Pattern 2 0.6 0.7 3.3 0.6 1.8 -0.9 0.4 -0.4 0.6 -0.7 -0.8 -0.1
Had menopause 0.1 0.1 0.4 -0.2 0.1 0.4 -0.1 -0.2 0.4 0.2 -0.6 -0.5
Had other major operations 0.1 0.2 0.5 0.1 0.1 0.1 0.6 -0.3 -0.5 0.1 0.5 -0.7
Forced vital capacity (FVC) 0.3 1.1 4.0 -0.1 -0.5 -0.4 -0.6 0.5 -0.9 -1.6 1.2 2.0
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.6 1.7 -1.0 -0.3 0.4 -0.3 -0.9 -1.2 -1.3 -0.3 -0.1
Ever unenthusiastic/disinterested for a whole week 0.8 1.0 2.9 0.9 1.7 -0.8 1.6 0.2 1.1 0.7 0.6 -0.5
Qualifications: None of the above 0.7 1.4 3.3 -1.5 -1.8 1.1 -0.9 -1.5 -0.9 -0.7 -1.2 -0.6
Financial difficulties in last 2 years 0.5 0.6 2.8 0.7 0.5 -1.7 0.3 0.2 0.4 -0.9 -0.3 1.0
Mouth/teeth dental problems 0.2 0.3 1.3 0.2 -0.1 0.7 0.1 0.5 0.2 1.1 0.1 -0.7
Heart attack 0.7 0.8 2.0 0.7 1.4 -0.2 0.8 0.4 1.1 1.4 0.2 -0.9
Allergy 0.2 0.4 1.7 0.2 0.2 -1.3 -0.3 0.1 0.1 -0.2 -1.2 0.6
Pain all over the body in last month 1.1 1.2 3.5 0.5 1.3 0.8 0.7 1.1 0.9 1.9 1.3 -0.3
Diabetes (self-reported) 1.5 2.2 5.3 1.6 0.7 -1.0 2.3 1.7 1.7 1.0 1.7 1.0
Hayfever/allergic rhinitis (self-reported) 0.1 0.1 0.2 0.5 -0.4 -0.4 0.5 -0.0 0.4 -0.2 0.2 -0.1
Medication: Ramipril 0.6 0.7 2.8 -0.1 -0.5 0.7 1.7 0.3 -0.7 0.5 1.4 -0.4
Medication: Simvastatin 0.4 0.7 1.8 0.9 0.9 -1.2 1.3 0.2 0.7 -0.2 -0.5 0.2
Fluid intelligence score 0.1 0.1 0.4 0.3 0.4 -0.0 -0.2 0.2 0.6 0.1 0.1 -0.4
Illnesses of siblings 0.2 0.3 1.4 0.7 1.2 -0.2 0.1 0.7 0.6 0.3 0.4 0.2
Neuroticism score 0.5 1.0 2.7 0.6 0.4 -0.0 1.3 1.5 0.4 0.2 1.6 1.2
Weight 3.7 18.3 34.1 4.7 5.8 -1.8 3.8 4.2 5.2 4.7 4.9 0.8
Impedance of arm (right) 1.2 5.7 12.6 -2.7 -2.5 2.2 0.1 -3.5 -2.4 -1.9 -2.4 -2.3
Arm fat percentage (right) 4.6 18.1 33.1 4.9 5.8 -2.5 5.0 3.4 5.4 4.1 4.0 0.4
Trunk fat-free mass 1.3 7.7 14.8 2.7 3.9 -0.5 0.5 3.4 2.9 3.6 3.8 0.7
Hip circumference 4.2 18.2 28.1 4.6 5.3 -2.3 4.2 4.3 5.3 4.7 4.7 1.0
Time employed in main current job 8.0 9.2 21.3 3.9 1.6 -4.6 2.9 2.7 3.2 -1.3 2.2 3.4
Alcohol intake versus 10 years previously 0.9 1.3 2.6 -1.5 -0.6 1.6 -0.9 -0.9 -1.1 0.7 -1.1 -1.4
Father’s age at death 0.1 0.1 0.3 0.1 0.1 -0.3 -0.3 -0.6 0.0 -0.4 -0.2 -0.3
Worrier / anxious feelings 1.0 1.9 3.4 1.5 1.3 -0.5 1.6 1.8 1.5 0.9 1.8 0.8
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 2.5 0.7 0.8 -1.6 0.6 -0.6 -0.2 -1.3 -1.1 0.2
Falls in the last year 0.4 0.6 2.0 0.4 1.4 0.5 -0.2 0.8 0.7 1.0 0.6 -0.3
Hair/balding pattern: Pattern 3 0.9 1.4 4.0 -1.5 -2.0 1.3 -0.8 -0.6 -1.8 -0.7 0.0 0.4
Number of live births 0.7 0.9 2.2 -1.1 -1.5 0.1 -0.9 -0.8 -1.3 -1.0 -0.9 0.2
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 2.0 0.8 0.6 -0.9 0.2 0.8 0.1 -0.7 1.3 1.4
Pulse rate 1.1 1.9 5.9 -1.2 -0.2 1.6 -2.4 -0.5 -0.8 1.1 -2.0 -0.8
Happiness 1.3 1.6 6.5 0.0 1.3 0.9 0.4 -0.5 0.7 2.2 0.1 -2.5
Noisy workplace 0.9 1.1 5.0 1.1 0.5 -1.2 -0.3 1.1 0.4 -0.5 0.7 2.2
Qualifications: A levels/AS levels or equivalent 0.0 0.1 0.2 0.1 -0.4 0.0 0.1 -0.0 -0.2 -0.4 0.2 0.2
Serious illness, injury or assault of a close relative in last 2 years 0.8 1.0 2.9 -0.5 -0.1 -0.4 -0.9 -1.3 -1.0 -1.3 -1.7 0.0
Mouth/teeth dental problems: Dentures 0.1 0.1 0.4 -0.4 -0.4 0.3 0.3 -0.2 0.1 0.3 0.7 -0.6
Asthma 0.6 1.1 2.2 1.2 1.4 -0.2 1.1 1.1 1.0 0.8 1.5 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.6 0.2 0.8 0.2 -0.1 -0.0 -0.2 -0.2 0.6 0.5
Medication: Cholesterol lowering 0.4 0.6 1.8 0.9 0.4 -1.3 0.6 0.5 0.9 -0.1 -0.5 0.8
Depression (self-reported) 0.6 0.7 2.1 0.4 1.0 -0.2 0.9 0.6 0.5 -0.3 1.5 1.2
Medication: Lansoprazole 1.9 2.1 4.3 1.9 1.4 -1.9 1.2 1.6 2.1 0.2 0.4 1.4
Prospective memory result 0.3 0.4 1.3 0.5 0.4 -1.1 1.0 -0.5 0.2 0.3 -0.2 -0.8
Lung cancer (father) 1.0 1.1 2.6 -1.2 -0.2 1.4 -1.3 -1.0 -0.5 0.8 -0.7 -1.6
Illnesses of mother 0.8 1.0 3.2 -0.7 -0.4 -0.1 -1.4 -1.2 -0.8 -1.8 -1.0 0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 3.1 0.8 0.6 -1.6 -0.3 0.8 -0.1 -0.8 0.6 1.8
Pulse wave Arterial Stiffness index 1.1 1.3 2.6 1.2 1.6 -0.8 1.3 0.9 1.6 1.0 1.1 0.4
Impedance of arm (left) 2.5 11.5 21.9 -3.9 -3.8 2.8 -1.0 -4.7 -3.8 -3.0 -3.8 -2.4
Arm fat mass (right) 4.5 18.7 34.1 4.9 5.8 -2.3 4.5 3.9 5.4 4.4 4.5 0.7
Trunk predicted mass 1.3 7.5 14.2 2.6 3.8 -0.4 0.5 3.3 2.9 3.6 3.8 0.5
Standing height 0.2 1.8 7.6 -1.1 0.2 2.8 -1.4 -0.2 -0.7 1.4 1.2 -1.1
Length of working week for main job 5.7 6.3 12.7 3.2 2.6 -3.6 2.9 2.1 2.2 -0.4 1.6 2.7
Exposure to tobacco smoke at home 0.4 0.5 1.3 -0.2 0.9 0.9 -0.0 -0.1 -0.2 1.0 0.2 -1.1
Breastfed as a baby 0.2 0.2 0.5 -0.2 -0.6 -0.3 -0.3 -0.7 -0.1 -0.2 -0.7 -0.7
Tense / ‘highly strung’ 0.3 0.6 2.3 -0.8 -0.7 0.5 -0.3 -0.3 -1.5 -0.7 -0.3 0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.2 -0.0 0.3 0.7 0.2 -0.1 0.6 1.1 0.5 -1.0
Hair/balding pattern: Pattern 4 1.5 3.6 10.7 -0.8 -2.3 -1.4 -1.6 -0.2 -1.3 -3.3 -0.9 2.9
Birth weight of first child 0.5 1.0 3.5 -0.7 -1.9 0.1 -1.4 -0.4 -0.7 -1.0 -1.0 0.5
Peak expiratory flow (PEF) 0.2 0.4 1.2 0.9 0.8 -0.5 0.5 0.5 0.4 0.1 1.1 0.2
Pulse wave reflection index 2.2 2.7 6.5 1.6 1.4 -1.0 2.5 1.7 1.4 0.6 2.5 1.1
Ever highly irritable/argumentative for 2 days 1.5 1.8 4.8 0.6 1.4 0.7 1.4 1.1 1.2 2.2 1.9 -0.7
Loud music exposure frequency 0.6 0.6 1.7 -0.9 -0.4 0.9 -1.3 0.3 -0.8 -0.7 -0.1 1.0
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 0.7 -0.8 -0.3 0.8 -0.8 -0.2 -0.7 -0.0 0.2 -0.0
Mouth/teeth dental problems: Bleeding gums 1.8 2.4 7.9 1.4 0.7 -2.8 1.3 0.3 0.4 -1.9 0.3 2.3
Blood clot in the leg (DVT) 1.4 1.8 3.3 -1.5 -1.1 1.7 -1.8 -1.2 -1.1 -0.6 -1.6 -0.8
Medication: Paracetamol 2.9 4.8 13.8 0.9 3.3 1.4 1.8 1.2 2.1 3.7 2.0 -1.8
Headache pain in last month 1.2 2.1 7.0 1.2 2.6 0.3 1.4 1.1 1.6 1.5 1.4 -0.3
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 3.0 -0.9 0.4 1.7 -0.6 -0.5 -0.3 1.0 0.5 -1.3
Glaucoma (self-reported) 0.3 0.4 0.8 0.5 -0.3 -0.8 0.7 0.2 0.3 -0.5 0.9 0.8
Gout (self-reported) 0.4 0.6 1.6 0.4 0.8 0.7 1.1 0.5 0.3 0.8 1.3 -0.1
Hypothyroidism/myxoedema (self-reported) 1.6 3.1 5.0 2.2 1.9 -1.8 1.9 1.9 2.1 1.3 1.4 0.9
Medication: Amlodipine 2.7 3.7 8.7 2.3 2.1 -2.1 2.3 1.7 2.9 1.2 0.8 0.5
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.2 -0.2 0.4 0.4 0.4 -0.3 0.4 1.1 0.2 -1.1
Birth weight 1.4 3.0 9.4 -1.6 -0.9 1.3 -3.1 -1.7 -1.5 -0.4 -2.1 -1.4
Chronic bronchitis/emphysema (mother) 3.9 4.6 8.6 -2.5 -1.7 1.8 -1.9 -2.7 -2.9 -1.7 -2.1 -1.5
High blood pressure (siblings) 0.3 0.5 1.9 0.5 -0.6 -0.7 1.4 0.0 0.0 -0.0 1.1 0.1
Forced vital capacity (FVC), Best measure 0.4 1.4 6.3 0.6 -0.1 -1.4 -0.3 1.0 -0.4 -1.2 1.0 2.5
Body fat percentage 3.7 14.8 28.4 4.3 5.3 -2.0 4.8 3.0 5.0 3.7 3.4 0.3
Leg fat percentage (right) 4.9 17.8 34.3 4.5 5.9 -1.9 4.3 3.7 5.5 4.8 3.9 -0.1
Arm fat-free mass (right) 1.7 8.6 15.8 3.1 4.0 -1.0 1.1 3.6 3.2 3.2 3.8 1.3
Exposure to tobacco smoke outside home 0.2 0.2 1.0 -0.1 0.4 0.2 -0.3 0.1 -0.3 -0.6 1.0 0.5
Comparative body size at age 10 0.2 0.5 1.3 0.8 0.9 -0.9 0.5 -0.4 1.1 -0.0 0.2 -0.1
Number of full brothers 0.2 0.3 0.8 0.6 0.6 0.0 0.1 0.1 0.8 0.8 -0.1 -0.9
Worry too long after embarrassment 0.4 0.6 1.4 -1.0 -0.8 1.2 -0.3 -0.3 -1.1 -0.5 0.7 0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.1 0.1 0.3 -0.3 0.5 0.1 -0.1 0.3 -0.1 0.5 -0.0 0.4
Wheeze or whistling in the chest in last year 0.6 1.0 4.0 0.3 1.1 0.9 1.1 0.3 0.7 2.0 0.7 -1.0
Number of children fathered 1.2 1.3 2.8 -1.3 -0.9 1.7 -1.1 -1.0 -0.7 0.7 -1.0 -1.6
Reason for reducing amount of alcohol drunk: Health precaution 6.0 7.0 11.2 -3.0 -3.4 0.9 -2.5 -2.4 -3.2 -3.2 -3.2 0.3
Age at first live birth 0.3 0.6 2.5 0.4 -0.5 -1.0 0.0 -0.3 -0.3 -1.6 -0.4 0.8
Pulse wave peak to peak time 0.9 1.1 2.2 -1.1 -1.4 0.8 -1.1 -0.8 -1.5 -1.0 -0.8 -0.4
Health satisfaction 0.2 0.3 1.0 -0.4 -0.4 1.0 0.6 -0.2 -0.7 -0.1 0.5 -0.1
Shortness of breath walking on level ground 0.4 0.5 1.2 0.8 0.9 -1.1 0.7 0.4 0.7 0.3 0.3 0.8
Qualifications: College or University degree 1.1 3.4 7.7 2.5 1.7 -2.8 1.8 1.8 1.5 -0.2 1.1 2.0
Eye problems/disorders: None of the above 0.3 0.3 1.2 -0.1 0.6 0.7 -0.5 0.5 -0.2 1.1 0.2 -0.4
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.6 -0.1 0.7 0.0 -0.2 -0.4 -0.3 -0.1 -0.8 -0.5
Emphysema/chronic bronchitis 0.4 0.4 1.2 -0.4 0.8 0.9 -0.4 -0.4 -0.1 0.8 -0.2 -1.1
Medication for pain relief, constipation, heartburn 0.7 1.2 4.2 -0.6 -2.0 -0.6 -0.4 -1.0 -1.2 -1.7 -0.7 0.2
Neck or shoulder pain in last month 0.2 0.3 1.0 0.3 1.0 0.2 0.8 -0.2 0.2 0.4 -0.4 -0.7
Medication: Blood pressure 1.1 2.0 4.9 1.8 0.8 -2.2 1.8 1.5 1.3 0.0 0.6 1.2
Angina (self-reported) 1.1 1.4 4.2 0.6 1.3 -0.3 0.3 -0.4 1.2 1.5 -1.6 -2.0
Migraine (self-reported) 0.3 0.4 0.8 0.6 0.0 -0.8 0.0 0.9 0.6 -0.6 0.6 0.8
Medication: Ibuprofen 0.3 0.3 1.4 0.2 0.4 -0.5 -0.2 -0.1 -0.5 -0.8 0.5 1.2
Medication: Allopurinol 1.5 2.0 3.7 1.2 1.7 0.4 1.9 1.2 1.3 1.9 1.7 -0.2
Medication: Omeprazole 5.7 6.8 14.5 -2.7 -1.5 3.3 -2.0 -3.3 -2.4 0.0 -2.2 -3.8
Medication: Seretide 50 evohaler 2.2 2.5 4.3 1.6 1.9 -0.0 1.3 1.7 1.8 2.1 1.9 0.6
Mean time to correctly identify matches 8.5 16.1 25.8 5.0 3.3 -5.1 4.5 3.9 4.1 -0.0 3.2 4.5
Heart disease (mother) 0.7 0.9 2.0 0.9 0.9 -0.3 1.2 1.0 1.2 1.4 0.6 -0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.3 1.3 -0.3 -0.4 1.1 -0.3 0.2 -0.3 0.5 0.4 -0.3
Whole body fat mass 4.5 18.6 35.6 4.8 6.0 -2.0 4.7 3.8 5.5 4.4 4.4 0.7
Leg fat mass (right) 5.7 22.1 40.3 5.2 6.3 -2.3 4.6 4.5 5.9 4.9 5.0 0.9
Arm predicted mass (right) 1.5 7.6 14.3 2.9 3.8 -0.9 1.0 3.4 3.1 3.0 3.4 1.2
Pulse rate, automated reading 0.3 0.9 3.6 0.4 0.9 0.9 -0.9 0.9 0.5 1.9 -0.7 -0.6
Alcohol intake frequency. 2.7 6.2 14.0 2.2 2.6 -0.4 2.5 2.5 3.5 3.7 2.5 -0.1
Comparative height size at age 10 0.7 4.0 9.2 1.9 2.4 -0.6 1.9 2.3 1.9 1.8 3.0 1.0
Number of full sisters 1.7 2.1 7.6 1.2 1.4 -0.4 1.3 1.1 1.3 2.8 1.6 -0.7
Suffer from ‘nerves’ 0.8 1.2 2.8 -1.5 -0.8 1.7 -1.4 -0.9 -1.4 -0.2 -0.4 -0.4
Overall health rating 1.8 3.9 8.7 2.3 2.9 -1.5 2.9 1.7 1.7 1.2 1.7 0.8
Chest pain or discomfort 1.0 1.5 4.9 0.3 1.7 1.0 0.8 0.0 1.0 2.2 0.2 -1.7
Had major operations 2.0 2.4 5.6 -1.8 -1.4 1.1 -0.5 -2.4 -1.9 -0.8 -1.4 -1.7
Age at last live birth 0.9 1.3 3.3 -0.8 -1.4 -0.2 -1.2 -1.0 -1.2 -1.8 -1.3 0.3
Family relationship satisfaction 0.3 0.4 1.8 -0.1 0.5 0.2 -0.0 -0.7 -0.4 0.5 -0.8 -1.3
Leg pain on walking 3.1 3.9 7.7 2.1 2.3 -1.5 2.8 2.0 2.1 0.8 2.0 1.5
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 1.6 0.2 1.2 -0.0 0.1 0.4 -0.1 0.8 0.2 -0.6
Commuting to job workplace: Car/motor vehicle 0.2 0.3 0.7 0.1 -0.5 -0.8 0.8 -0.5 0.1 -0.8 -0.3 0.1
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 2.4 -0.5 -0.8 1.1 0.1 -0.6 0.1 0.8 0.1 -1.5
Medication: Aspirin 2.4 3.2 6.2 2.2 1.4 -2.2 2.5 1.8 2.4 0.8 0.8 0.9
Supplements: Vitamin C 2.8 3.3 8.6 2.0 1.2 -1.9 2.9 1.1 1.7 -0.8 1.9 2.0
Knee pain experienced in last month 0.9 1.4 2.4 1.0 1.4 -0.6 0.7 1.6 1.4 0.6 1.4 1.4
Hypertension (Self-reported) 4.5 12.6 19.7 4.4 3.1 -4.0 4.0 4.1 3.9 2.3 3.2 2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.0 2.4 4.9 1.7 2.1 -0.3 1.2 1.7 2.2 2.0 0.9 0.1
Illnesses of father: Heart disease 2.4 3.4 10.1 -1.3 -3.2 -0.4 -0.8 -1.9 -1.9 -2.4 -2.1 -0.3
Illnesses of siblings: Diabetes 0.7 0.9 3.4 -0.3 -0.5 -1.0 -1.0 -0.6 -0.4 -1.3 -1.8 0.1
Smoking status: Previous 6.9 10.3 16.9 -3.7 -3.8 2.7 -2.7 -4.1 -3.7 -2.0 -2.7 -2.9
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.0 7.3 -1.4 0.1 2.7 -2.1 -0.1 -1.2 1.4 -0.1 -0.9
Whole body fat-free mass 1.8 10.4 19.0 3.4 4.4 -0.9 1.5 3.8 3.5 3.8 4.3 1.0
Leg fat-free mass (right) 1.9 10.4 19.0 3.6 4.0 -1.5 2.5 3.5 3.5 3.1 4.4 1.4
Arm fat percentage (left) 3.8 15.0 28.9 4.4 5.4 -2.3 4.7 3.0 5.0 3.7 3.5 0.4
Average weekly red wine intake 0.6 0.8 2.5 0.3 -1.0 -1.1 -0.1 -0.7 -0.4 -1.6 -1.4 0.4
Handedness (chirality/laterality): Left-handed 0.2 0.2 1.0 -0.4 -0.1 0.1 -1.0 -0.3 -0.1 0.5 -0.8 -0.0
Mood swings 1.3 2.4 4.1 1.8 1.9 -1.0 2.0 1.6 1.8 0.5 1.8 0.6
Loneliness, isolation 0.2 0.3 2.1 0.1 1.4 -0.1 0.4 0.4 0.1 0.4 -0.0 0.1
Long-standing illness, disability or infirmity 0.1 0.1 0.5 0.4 0.7 -0.1 0.0 0.2 0.5 0.3 -0.3 -0.0
Ever had bowel cancer screening 1.0 1.2 3.8 0.8 0.4 -1.9 0.6 -0.9 0.9 -1.6 -0.9 0.8
Diabetes diagnosed by doctor 1.8 2.9 6.2 1.8 1.2 -1.2 2.5 1.9 2.0 0.8 2.0 1.4
Ever had stillbirth, spontaneous miscarriage or termination 3.4 3.6 5.8 -2.1 -2.1 0.8 -1.9 -2.2 -2.0 -2.0 -2.4 -1.0
Friendships satisfaction 0.7 0.9 2.4 0.8 1.4 -0.8 1.5 -0.0 0.9 0.8 0.4 -0.8
Qualifications: nursing, teaching 2.8 4.4 8.4 2.9 2.7 -1.7 1.3 2.2 2.8 1.2 1.6 1.5
Commuting to job workplace: Walk 1.9 2.1 4.5 -1.6 -1.2 2.1 -1.6 -1.2 -1.6 0.1 -0.8 -1.7
Eye problems/disorders: Cataract 0.1 0.1 0.3 -0.1 -0.5 -0.1 0.2 -0.3 -0.3 -0.5 -0.1 0.3
Mouth/teeth dental problems: Mouth ulcers 0.8 1.3 3.7 -0.4 -0.4 -1.0 -1.2 -1.2 -0.8 -1.9 -1.4 1.0
Medication for cholesterol 1.7 2.6 4.8 -2.1 -0.9 1.8 -2.1 -1.6 -2.2 -0.7 -1.4 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 1.6 0.4 1.0 -0.1 0.7 0.9 0.1 0.2 1.3 0.5
Back pain experienced in last month 0.9 1.4 3.0 -1.0 0.3 1.5 -1.3 -0.9 -1.1 0.5 -1.4 -1.7
Mineral and other dietary supplements 1.4 1.8 5.0 -0.1 1.1 1.8 0.3 0.5 1.0 2.2 1.7 -1.7
Breast cancer (self-reported) 0.4 0.5 1.0 0.6 -0.1 -1.0 0.8 0.7 0.4 -0.6 0.7 1.0
Asthma (self-reported) 0.7 1.5 2.9 1.4 1.6 -0.4 1.4 1.2 1.1 0.9 1.7 0.4
Osteoporosis (self-reported) 1.3 1.6 4.4 1.0 2.1 0.1 0.8 1.4 1.4 1.7 1.0 -0.7
Osteoarthritis (self-reported) 0.2 0.3 1.2 0.2 0.7 0.3 -0.1 -0.2 0.6 1.1 0.5 -0.6
Medication: Aspirin 1.6 2.0 3.8 1.8 1.0 -1.8 1.9 1.5 1.9 0.7 0.5 0.8
Medication: Gliclazide 1.7 1.9 4.8 1.4 0.7 -1.5 2.2 1.5 1.1 0.3 1.0 1.6
Illnesses of father: None of the above (group 1) 0.7 0.8 2.0 0.6 1.4 0.2 0.5 1.2 0.7 1.1 1.1 0.5
Smoking status: Current 0.7 1.1 2.0 -1.4 -0.3 1.3 -1.4 -0.7 -1.4 -0.0 -1.2 -0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.5 4.1 1.0 0.3 -2.0 0.9 -0.1 0.1 -1.9 0.1 2.0
Whole body water mass 1.6 9.1 16.9 3.1 4.0 -0.7 1.3 3.5 3.3 3.7 4.1 0.8
Leg predicted mass (right) 1.9 10.0 18.3 3.6 4.0 -1.5 2.4 3.4 3.4 3.0 4.3 1.3
Arm fat mass (left) 4.7 19.3 35.5 5.0 6.0 -2.5 4.7 3.9 5.5 4.3 4.4 0.7
Number of self-reported non-cancer illnesses 5.5 9.5 16.0 4.0 3.0 -3.6 3.8 2.7 3.7 1.6 2.7 1.6
Average weekly champagne plus white wine intake 0.5 0.7 2.8 -0.4 -0.3 1.2 -0.3 -0.2 -0.1 1.4 -0.0 -1.7
Miserableness 0.4 0.8 2.9 0.7 0.2 -0.4 1.1 1.1 0.7 -0.1 1.7 0.5
Guilty feelings 1.3 2.0 4.9 0.9 0.8 0.2 2.2 1.7 1.2 1.7 2.1 0.2
Wears glasses or contact lenses 0.4 0.4 1.5 -0.6 0.5 0.3 -0.8 -0.4 0.2 0.5 -1.2 -0.5
Ever taken oral contraceptive pill 0.4 0.4 1.3 0.7 0.8 -1.1 -0.1 0.4 0.3 -0.7 -0.5 0.8
Hearing aid user 2.1 2.4 5.8 -1.5 -1.1 1.3 -1.1 -2.4 -1.7 -0.7 -1.5 -2.0
Mother’s age at death 1.3 1.7 3.7 1.8 1.7 -1.7 0.8 0.8 1.9 0.6 0.7 0.7
Financial situation satisfaction 0.2 0.3 0.8 -0.7 0.3 0.2 -0.4 -0.8 -0.7 -0.9 -0.2 -0.0
Tinnitus: Yes, now most or all of the time 1.1 1.3 3.2 -1.4 -1.2 1.8 -1.1 -0.9 -1.2 -0.6 -1.2 -0.3
Commuting to job workplace: Public transport 1.4 1.6 5.1 0.7 1.8 0.7 0.5 1.5 1.2 2.3 0.8 -0.8
Eye problems/disorders: Glaucoma 1.3 1.6 2.4 1.6 0.9 -1.4 0.9 1.3 1.4 0.5 1.4 1.4
Medication: Blood pressure 2.4 4.6 8.0 2.7 1.4 -2.3 2.8 2.1 2.6 1.2 2.4 0.6
Pain type(s) experienced in last month: Hip pain 0.8 1.1 2.8 1.2 1.7 -1.1 1.6 -0.0 1.2 0.1 -0.1 -0.4
Supplements: Fish oil (including cod liver oil) 1.2 1.5 3.1 -0.7 -1.7 -0.2 -0.4 -1.3 -1.6 -1.8 -1.6 0.2
High cholesterol (Self-reported) 2.3 4.1 7.7 2.7 1.8 -2.5 2.2 1.8 2.8 0.2 1.1 1.7
Medication: Bendroflumethiazide 5.3 8.1 11.6 3.2 1.5 -3.2 3.3 3.3 2.6 0.1 3.1 3.4
Medication: Paracetamol 2.7 4.2 15.5 0.1 2.8 2.0 0.7 0.5 1.4 3.9 1.3 -2.5
Medication: Lisinopril 6.3 8.2 12.7 3.6 2.2 -2.9 3.5 3.3 3.3 1.1 3.0 1.9
Medication: Atorvastatin 1.2 1.5 5.0 0.7 0.9 0.7 0.6 0.6 1.8 2.2 0.9 -1.4
Illnesses of father: High blood pressure 0.8 1.0 3.5 0.5 -0.2 -1.6 -0.2 -0.6 -0.2 -1.9 -1.2 0.9
Alcohol drinker status: Never 2.0 2.4 6.1 1.9 1.1 -1.9 1.6 1.3 2.5 1.0 0.8 1.1
Ever smoked 3.1 5.4 8.7 -2.7 -2.3 2.3 -2.3 -2.8 -3.0 -1.6 -1.8 -1.7
Basal metabolic rate 2.3 12.7 23.2 3.9 4.8 -1.3 2.2 3.9 4.0 4.0 4.6 1.0
Leg fat percentage (left) 4.0 14.3 28.0 4.0 5.3 -1.7 3.9 3.3 4.9 4.4 3.5 -0.2
Arm fat-free mass (left) 2.1 10.8 18.4 3.5 4.3 -1.2 1.5 3.9 3.9 3.9 4.1 0.9
Number of operations (self-reported) 1.2 1.8 3.8 -1.2 -1.9 0.5 -1.1 -1.7 -1.6 -1.1 -1.4 -1.0
Average weekly beer plus cider intake 1.5 2.1 4.5 1.3 0.8 -1.4 0.8 2.1 1.3 0.4 2.0 2.1
Irritability 1.2 2.0 4.9 1.5 0.5 -1.3 1.4 1.9 1.0 -0.4 1.5 2.2
Risk taking 0.9 1.4 4.4 1.2 0.2 -2.0 -0.1 0.7 0.0 -1.4 0.3 2.1
Ever had prostate specific antigen (PSA) test 0.4 0.5 2.1 -0.4 -1.5 -0.2 -0.5 -0.5 -0.5 -0.6 -0.7 -0.5
Fractured/broken bones in last 5 years 0.6 0.7 1.7 -1.1 -0.4 1.2 -1.3 -0.5 -0.9 -0.6 -0.5 -0.2
Age started oral contraceptive pill 0.3 0.4 1.2 -0.2 -0.5 1.1 0.0 0.6 0.1 1.1 0.1 -0.6
Diastolic blood pressure, automated reading 4.7 14.5 20.8 4.4 4.2 -3.1 3.7 4.6 3.9 2.6 4.3 3.0
Ever depressed for a whole week 0.7 0.8 3.5 0.2 1.0 0.4 0.5 0.4 0.5 1.9 0.7 -1.2
Unable to work because of sickness or disability 1.3 1.7 5.4 1.2 2.3 -0.7 1.1 1.3 1.1 1.7 0.9 -0.3
Commuting to job workplace: Cycle 0.3 0.4 0.9 0.3 0.3 0.1 -0.5 1.0 0.5 0.5 0.9 0.8
Myopia 0.2 0.3 0.7 0.0 0.1 -0.8 -0.6 -0.2 0.4 -0.8 -0.9 0.3
Vascular/heart problems diagnosed by doctor 5.3 14.4 23.1 -4.8 -3.5 4.4 -4.3 -4.2 -4.3 -2.2 -3.2 -2.3
Cholesterol lowering medication 0.8 1.2 5.1 1.3 0.6 -1.1 2.2 -0.1 1.4 -0.3 0.2 -0.4
Medication: Omeprazole (e.g. Zanprol) 5.6 6.8 13.8 -2.9 -1.5 3.6 -2.3 -3.0 -2.3 0.3 -2.1 -3.7
Pain experienced in last month 0.6 1.0 2.6 -0.1 -1.4 -1.3 -0.6 -0.7 -0.3 -1.6 -0.9 1.0
Supplements: Calcium 1.3 1.4 4.2 -0.3 -1.5 -1.3 -0.8 -0.5 -0.7 -2.1 -1.5 1.1
Basal cell carcinoma (self-reported) 0.0 0.1 0.2 0.1 0.1 -0.1 -0.2 0.0 0.5 -0.2 0.2 -0.3
Heart attack/myocardial infarction (self-reported) 0.6 0.7 2.3 0.3 1.2 0.4 0.4 0.2 0.8 1.5 0.1 -1.3
Deep venous thrombosis (DVT) (self-reported) 1.2 1.5 2.9 -1.3 -1.0 1.4 -1.7 -1.1 -0.9 -0.5 -1.7 -0.9
Heart disease (siblings) 0.2 0.3 1.4 -0.2 -0.3 0.1 -0.4 -0.5 -0.0 -0.7 -1.2 0.2
Alcohol drinker status: Previous 2.1 2.4 3.8 1.8 1.9 -1.4 1.4 1.9 1.7 1.8 1.0 0.6
Pack years of smoking 0.5 0.7 2.2 -0.6 0.4 0.9 -0.4 -0.3 0.4 1.2 -0.7 -1.5
Impedance of whole body 2.0 10.1 16.7 -3.8 -3.6 2.5 -1.4 -4.1 -3.5 -2.7 -3.8 -2.1
Leg fat mass (left) 5.1 20.0 36.7 5.0 6.1 -2.2 4.5 4.3 5.6 4.6 4.7 0.8
Arm predicted mass (left) 2.3 11.9 21.0 3.6 4.6 -1.1 1.6 4.0 4.0 4.2 4.3 0.7