Best TWAS P=1.03e-10 · Best GWAS P=3.98e-12 conditioned to 0.00361
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | C2orf69 | 0.07 | 0.10 | enet | 17 | 0.10 | 2.7e-08 | 4.7 | 5.3 | 1.3e-07 | 0.47 | 0.96 | 0.03 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | SPATS2L | 0.13 | 0.06 | lasso | 2 | 0.07 | 1.1e-04 | 6.4 | 6.5 | 1.0e-10 | 0.81 | 0.06 | 0.92 | TRUE |
| 3 | GTEx | Spleen | KCTD18 | 0.26 | 0.03 | lasso | 4 | 0.04 | 3.8e-02 | 4.6 | 5.5 | 4.4e-08 | 0.42 | 0.09 | 0.47 | FALSE |
| 4 | GTEx | Testis | C2orf69 | 0.14 | 0.09 | enet | 17 | 0.10 | 2.7e-05 | 4.8 | 5.5 | 3.7e-08 | 0.59 | 0.40 | 0.45 | FALSE |