Best TWAS P=2.67e-09 · Best GWAS P=4.6e-08 conditioned to 0.0632
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | MMEL1 | 0.07 | 0.08 | lasso | 4 | 0.08 | 5.5e-12 | -5.3 | 5.3 | 1.1e-07 | 0.36 | 0.02 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Soft Tissue Sarcoma | MMEL1 | 0.05 | 0.01 | blup | 38 | 0.02 | 1.7e-02 | 5.1 | 6.0 | 2.7e-09 | 0.69 | 0.02 | 0.58 | TRUE |
| 3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | MMEL1 | 0.13 | 0.14 | lasso | 6 | 0.13 | 2.2e-05 | -5.3 | 5.3 | 1.1e-07 | 0.36 | 0.02 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MMEL1 | 0.05 | 0.07 | blup | 38 | 0.07 | 2.1e-07 | -5.3 | 5.4 | 7.1e-08 | 0.41 | 0.02 | 0.98 | FALSE |