[Hub]/) : Traits : Rheumatoid Arthritis : ← →

chr1:37,628,741-39,108,725

Best TWAS P=1.9e-08 · Best GWAS P=7.62e-08 conditioned to 9.04e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-109P14.10 0.28 0.21 lasso 4 0.22 6.0e-18 4.8 5.3 1.3e-07 -0.09 0.04 0.95 FALSE
2 GTEx Adipose Visceral Omentum INPP5B 0.34 0.14 lasso 4 0.25 3.7e-13 -4.2 5.5 4.0e-08 -0.09 0.10 0.90 FALSE
3 GTEx Colon Sigmoid INPP5B 0.43 0.15 lasso 6 0.31 1.2e-11 3.2 5.3 1.3e-07 -0.09 0.08 0.91 FALSE
4 GTEx Lung INPP5B 0.32 0.22 lasso 6 0.26 8.4e-20 4.8 5.2 1.9e-07 -0.05 0.05 0.95 FALSE
5 GTEx Nerve Tibial INPP5B 0.24 0.17 lasso 6 0.20 3.5e-14 -4.2 5.2 2.2e-07 -0.07 0.45 0.53 FALSE
6 GTEx Spleen INPP5B 0.77 0.51 lasso 7 0.66 2.5e-22 4.8 5.4 5.4e-08 -0.08 0.05 0.95 FALSE
7 GTEx Spleen RP11-109P14.10 0.59 0.36 lasso 5 0.45 6.2e-13 -4.2 5.4 7.3e-08 -0.07 0.20 0.77 FALSE
8 GTEx Thyroid INPP5B 0.14 0.06 lasso 4 0.09 1.0e-07 4.8 5.5 4.5e-08 -0.09 0.10 0.89 FALSE
9 METSIM Adipose INPP5B 0.31 0.33 enet 21 0.35 2.4e-54 4.9 5.3 1.1e-07 -0.08 0.04 0.96 FALSE
10 ROSMAP Brain Pre-frontal Cortex INPP5B 0.22 0.16 lasso 3 0.20 8.0e-25 4.9 5.6 1.9e-08 -0.09 0.03 0.97 TRUE