Hub : Genes

MPHOSPH9

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0490	0.0220	4.9e-04	0.016	0.015	0.001	0.018	0.005	4.0e-03	5.1e-03	2.1e-01	2.6e-03	7.8e-02
2	GTEx	Adipose Visceral Omentum	0.0740	0.0390	6.9e-03	0.016	NA	-0.003	NA	-0.001	4.5e-02	NA	4.9e-01	NA	3.5e-01
3	GTEx	Artery Aorta	0.0780	0.0340	4.2e-04	0.012	NA	0.017	NA	0.036	6.5e-02	NA	3.9e-02	NA	4.6e-03
4	GTEx	Artery Tibial	0.0469	0.0237	3.4e-03	0.027	NA	0.026	NA	0.029	3.1e-03	NA	3.6e-03	NA	2.2e-03
5	GTEx	Esophagus Muscularis	0.1790	0.0580	1.9e-08	0.177	NA	0.179	NA	0.164	6.4e-11	NA	4.8e-11	NA	3.3e-10
6	GTEx	Heart Left Ventricle	0.0629	0.0306	3.5e-03	0.045	NA	0.022	NA	0.038	2.0e-03	NA	2.4e-02	NA	4.2e-03
7	GTEx	Nerve Tibial	0.0723	0.0310	6.5e-04	0.043	NA	-0.001	NA	0.009	5.0e-04	NA	3.7e-01	NA	7.0e-02
8	GTEx	Pancreas	0.1350	0.0550	6.5e-04	0.015	NA	0.066	NA	0.019	7.5e-02	NA	9.3e-04	NA	5.0e-02
9	GTEx	Skin Sun Exposed Lower leg	0.0620	0.0270	5.5e-04	0.045	NA	0.056	NA	0.032	1.2e-04	NA	2.1e-05	NA	1.1e-03
10	GTEx	Stomach	0.1650	0.0650	4.2e-05	0.080	NA	0.099	NA	0.104	1.2e-04	NA	1.8e-05	NA	1.2e-05
11	GTEx	Testis	0.2840	0.0680	5.8e-15	0.267	NA	0.316	NA	0.306	3.0e-12	NA	1.3e-14	NA	4.3e-14
12	GTEx	Thyroid	0.1030	0.0370	9.0e-08	0.077	NA	0.091	NA	0.086	1.6e-06	NA	2.0e-07	NA	4.0e-07
13	METSIM	Adipose	0.0263	0.0153	4.9e-03	0.015	0.008	0.002	0.009	0.002	2.3e-03	2.0e-02	1.6e-01	1.2e-02	1.6e-01
14	YFS	Blood	0.0473	0.0150	0.0e+00	0.073	0.070	0.074	0.070	0.073	9.5e-23	8.3e-22	3.7e-23	5.2e-22	1.2e-22
15	TCGA	Thyroid Carcinoma	0.2730	0.2700	3.8e-07	0.094	0.059	0.077	NA	0.086	2.1e-09	1.9e-06	5.5e-08	NA	9.8e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	2.9	4.6	7.5	-2.6	2.4	1.5	2.3	1.4	2.7	2.7	-1.3	1.7	2.2	2.2	2.2	0.6	2.6	2.5
Bipolar Disorder or Schizophrenia	8.3	20.3	32.1	-5.2	5.1	3.5	4.7	3.5	5.7	4.9	-2.3	3.6	4.8	5.4	5.0	2.3	5.1	4.6
Depressed Affect (Nagel 2018)	4.0	8.4	22.1	-0.2	-3.1	-2.2	-2.8	-2.8	-2.8	-3.0	4.7	-2.9	-2.6	-3.1	-2.6	-3.2	-2.5	-2.8
Depression (Nagel 2018)	0.9	1.4	2.7	-0.3	-1.0	-1.1	-1.6	-1.6	-0.5	-1.1	1.2	-1.3	-1.2	-1.4	-0.8	-1.3	-1.2	-1.3
Intelligence (Savage-Jansen 2018)	6.8	20.8	30.9	-4.0	4.7	4.5	4.7	4.6	4.4	4.6	-2.2	4.9	5.1	5.6	5.1	3.6	5.3	4.2
Neuroticism (Nagel 2018)	2.2	5.2	13.1	-1.0	-2.4	-1.8	-2.3	-2.5	-2.3	-2.5	3.6	-2.4	-2.1	-2.3	-1.9	-2.1	-2.0	-2.1
Schizophrenia (2018)	7.9	16.4	26.6	-4.5	4.1	3.1	4.3	3.3	5.0	4.2	-2.0	3.7	4.3	5.2	4.7	2.7	4.5	3.9
Schizophrenia vs Biploar Disorder	3.6	4.8	9.2	0.3	1.7	2.3	2.0	2.4	2.5	2.4	-2.2	3.0	2.1	2.4	2.0	2.7	2.1	1.4
Worry (Nagel 2018)	0.6	1.3	2.6	-0.2	-1.2	-0.7	-1.1	-1.6	-1.6	-1.3	1.5	-1.0	-1.0	-1.3	-1.1	0.3	-1.0	-0.9
Alzheimer’s Disease (in mother)	1.3	1.6	5.5	-0.5	-0.0	1.4	1.4	0.9	0.5	0.5	-1.8	1.9	1.0	1.1	1.2	2.3	0.3	1.2
Alzheimer’s Disease (in father)	0.3	0.3	1.7	0.5	-0.4	0.5	0.1	0.1	0.6	0.2	-1.1	0.5	0.1	0.1	-0.2	1.3	-0.3	-0.1
Alzheimer’s Disease (including proxy)	0.4	0.6	3.8	1.0	-0.7	0.5	-0.0	-0.1	-0.2	-0.4	-1.9	0.4	-0.2	-0.4	-0.3	1.3	-0.9	0.1
Crohns Disease (2017)	2.2	4.8	7.7	-0.5	1.6	2.1	2.5	2.3	2.7	2.5	-1.7	2.8	2.0	2.2	2.1	2.2	2.3	2.3
Irritable Bowel Disease (IBD)	0.7	1.8	3.1	-0.5	1.2	1.0	1.5	1.1	1.8	1.6	-1.1	1.4	1.3	1.4	1.5	1.3	1.5	1.2
Ulcerative Colitis (UC)	0.1	0.1	0.3	-0.4	0.6	-0.5	0.1	-0.4	0.2	0.0	0.2	-0.5	0.0	0.2	0.3	-0.1	0.3	0.0
Major Depression (MDD)	3.5	4.2	8.4	2.6	-2.6	-1.4	-2.4	-1.0	-1.8	-2.0	1.3	-1.3	-2.1	-2.1	-2.4	-1.7	-2.1	-2.9
Reaction Time	2.7	5.2	8.0	0.8	-1.9	-2.8	-1.8	-1.9	-2.8	-2.8	2.5	-2.8	-2.2	-2.0	-2.3	-2.4	-2.4	-2.0
Verbal and Numeric Reasoning (VNR)	5.6	13.4	20.2	-2.6	3.3	4.5	3.4	3.6	3.2	3.5	-1.2	4.5	4.0	4.4	4.1	3.3	4.5	3.4
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	3.0	4.0	6.3	1.0	-2.1	-1.5	-2.0	-1.6	-2.1	-2.5	2.3	-2.2	-2.0	-1.8	-2.4	-2.2	-2.3	-1.5
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	3.4	4.9	7.1	-1.1	2.1	1.8	2.1	2.1	2.7	2.6	-2.0	2.4	2.4	2.2	2.5	2.1	2.3	2.6
Bipolar Disorder (2011)	1.1	1.1	5.3	-2.3	1.4	0.6	1.2	0.3	0.9	0.9	-0.4	0.3	0.8	1.0	1.2	1.1	0.9	0.0
Body Mass Index (BMI) (2010)	3.0	4.2	7.2	-2.6	2.4	1.8	2.1	1.4	2.4	2.2	-0.2	1.4	2.1	2.3	2.7	1.1	2.2	2.2
Coronary Artery Disease (CAD)	0.4	0.5	2.0	-0.1	0.7	1.4	0.5	0.6	0.7	0.6	-0.5	0.9	0.7	0.7	0.8	0.2	0.8	0.0
Crohns Disease (2012)	1.8	2.9	5.8	-0.1	0.9	2.0	1.9	1.4	1.9	1.9	-2.4	2.1	1.4	1.2	1.5	1.4	1.6	2.2
Mean Putamen Volume	0.8	1.0	2.5	-0.9	0.7	0.8	0.9	0.4	1.4	1.6	0.1	1.5	0.7	0.9	0.8	0.7	1.4	0.8
Fasting Glucose	0.3	0.3	1.8	-0.4	-0.1	1.4	-0.6	-0.2	-0.4	-0.3	0.9	-0.1	0.1	-0.1	0.2	0.7	0.1	-0.9
HbA1C	0.2	0.2	1.0	-0.2	0.5	0.3	0.3	-0.4	-0.4	-0.3	0.2	-1.0	-0.1	-0.2	-0.1	-0.8	0.1	0.6
HDL Cholesterol	0.8	1.4	13.3	-1.9	0.5	0.3	1.2	-0.3	0.4	0.2	3.7	-0.0	0.4	0.8	0.8	-0.3	0.7	0.3
LDL Cholesterol	0.4	0.7	7.7	-2.8	-0.1	-0.1	-0.2	-0.1	0.3	-0.2	1.0	-0.7	0.6	0.2	0.4	-0.4	-0.2	-0.2
Lupus	0.5	0.8	4.1	-0.4	-0.9	-0.6	-0.6	-0.8	-0.2	-0.6	1.4	-1.1	-0.6	-0.7	-0.7	-2.0	-0.7	-0.8
Neuroticism (2016)	0.7	1.0	6.7	-1.7	-0.9	-0.4	-1.0	-1.0	-0.8	-0.8	2.6	-0.3	-0.3	-0.5	0.3	-0.9	-0.2	-0.3
Primary Biliary Cirrhosis	5.0	7.1	10.1	-2.9	3.1	2.5	2.8	2.4	3.1	3.0	-0.5	1.9	2.9	3.2	3.2	1.1	3.0	2.6
Rheumatoid Arthritis	1.1	1.5	4.7	0.4	-0.8	0.1	-1.2	-1.0	-1.1	-1.1	1.8	-1.4	-1.3	-0.9	-1.5	-2.2	-0.7	-1.0
Schizophrenia (2014)	10.5	23.1	35.2	-4.3	4.9	3.9	5.3	4.2	5.9	5.1	-3.4	4.7	5.0	5.8	5.5	3.1	5.2	4.8
Triglycerides	0.6	1.0	2.2	0.6	-1.3	-0.7	-1.5	-0.7	-0.5	-1.0	-0.1	-1.2	-0.9	-1.2	-1.3	-1.2	-1.0	-0.7
Type 2 Diabetes (T2D) (2012)	7.4	8.5	15.5	2.5	-3.1	-3.3	-3.5	-3.4	-2.2	-2.7	1.6	-2.9	-3.5	-3.1	-3.9	-2.9	-3.0	0.0
Ulcerative Colitis	0.1	0.1	0.5	0.2	0.3	-0.2	-0.3	0.0	0.2	0.0	-0.5	-0.3	0.0	0.1	0.2	-0.2	0.0	0.7
Blood Eosinophil Count	7.3	56.0	90.4	1.3	-7.3	-6.1	-8.0	-8.2	-7.5	-8.4	9.5	-8.7	-7.5	-7.5	-6.9	-7.6	-7.7	-6.9
Blood Platelet Count	10.8	124.7	156.2	6.8	-12.0	-8.3	-12.2	-10.8	-12.1	-12.5	11.9	-11.5	-12.0	-12.1	-11.5	-9.0	-11.8	-11.2
Blood Red Count	1.1	10.3	22.5	2.8	-3.1	-4.0	-2.4	-3.4	-4.7	-3.5	1.8	-2.8	-3.8	-3.9	-3.4	-2.1	-2.7	-1.8
Blood White Count	0.2	1.6	9.7	-1.0	-1.1	-0.3	-0.2	-1.1	-0.1	-0.9	3.1	-1.6	-0.6	-0.9	0.2	-1.8	-1.2	-1.1
Heel T-Score	10.7	85.1	108.2	4.7	-9.2	-9.6	-9.2	-9.2	-10.4	-10.4	7.3	-9.9	-10.3	-9.7	-9.9	-8.9	-9.6	-8.3
BMI	0.7	4.0	18.8	-1.7	0.3	-4.1	-0.2	-2.3	-0.3	-0.7	1.9	-2.8	-1.5	-1.2	-0.6	-4.3	-0.4	-0.4
Height	13.2	255.2	358.2	-4.8	16.9	16.3	15.9	17.8	18.2	18.9	-13.7	17.1	17.5	16.4	16.3	13.6	16.9	14.4
Waist Hip Ratio (WHR)	11.5	51.8	86.7	9.0	-9.3	-3.3	-8.8	-5.5	-7.5	-7.2	4.4	-5.3	-8.0	-8.8	-7.8	-3.0	-8.0	-7.7
Systolic Blood Pressure	0.6	3.2	6.0	2.5	-1.8	-1.8	-1.4	-1.2	-2.4	-1.7	1.5	-1.5	-1.9	-2.0	-2.1	0.3	-1.9	-1.8
Smoking Status	0.5	1.3	3.5	1.7	-1.7	-0.4	-1.3	-1.1	-0.5	-0.8	0.8	-0.0	-1.1	-0.9	-0.8	-1.9	-0.4	-1.6
Allergy or Eczema	9.1	24.0	39.8	1.2	-4.7	-4.7	-5.2	-6.3	-5.1	-5.9	2.9	-5.6	-5.2	-5.4	-4.4	-4.9	-5.4	-4.1
Cardiovascular Disease	1.2	4.0	24.0	-1.4	-1.3	-2.1	-1.4	-2.0	-1.9	-1.7	4.9	-2.1	-1.2	-1.3	-1.1	-1.9	-1.0	-1.5
Hypothyroidism (self reported)	2.9	6.6	12.1	-3.5	3.4	1.6	2.7	2.4	2.1	2.4	0.2	1.8	3.2	3.3	2.9	1.8	2.8	2.2
Respiratory disease	4.6	10.2	17.9	0.3	-3.9	-2.3	-3.4	-4.2	-3.3	-3.9	3.5	-3.0	-3.5	-3.4	-2.7	-2.9	-3.2	-2.4
Type 2 Diabetes (T2D) (2018)	6.0	11.2	30.5	2.1	-3.2	-2.8	-3.3	-3.0	-3.2	-3.0	5.5	-3.2	-3.4	-3.5	-3.1	-4.2	-2.5	-2.9
Lung FEV1/FVC ratio	1.5	7.6	11.7	3.4	-2.9	-2.6	-3.0	-1.5	-2.5	-2.6	2.1	-2.9	-2.8	-3.2	-2.9	-2.5	-2.9	-3.1
Lung FVC	4.4	22.5	33.1	4.3	-4.7	-3.6	-5.1	-5.5	-5.2	-5.3	1.8	-4.6	-5.5	-5.1	-5.8	-4.7	-4.5	-4.3
Neuroticism	1.6	3.8	12.7	-2.3	-1.7	-2.0	-1.6	-2.3	-1.8	-1.8	3.6	-2.1	-1.7	-1.7	-1.1	-1.9	-1.3	-1.5
Chronotype (morning person)	0.8	1.8	3.9	-0.7	1.5	0.5	1.2	1.3	1.3	1.9	-0.3	1.7	1.7	1.4	1.6	1.0	2.0	0.1
Hair Pigment	1.1	31.7	43.0	3.1	-6.0	-4.9	-6.1	-5.7	-6.0	-6.6	4.2	-6.1	-6.3	-6.2	-6.0	-4.7	-6.2	-5.3
Tanning	0.2	2.0	4.9	-1.6	1.2	1.1	1.6	0.5	1.9	1.5	-0.8	1.3	1.4	1.4	1.2	-0.7	1.8	2.2
Hand grip strength (left)	0.3	0.9	5.9	1.8	0.8	0.5	0.5	0.2	0.8	1.0	-2.4	0.4	0.3	-0.1	0.4	-0.3	0.7	0.2
Number of treatments/medications taken	2.1	3.7	11.7	-0.8	-1.5	-1.4	-2.1	-2.0	-1.5	-2.0	3.4	-2.4	-1.5	-1.6	-0.9	-2.8	-1.6	-1.8
Average weekly spirits intake	1.8	2.3	5.4	-0.5	-1.1	-1.8	-1.4	-1.8	-1.3	-1.9	1.1	-2.3	-1.5	-1.8	-1.3	-1.2	-1.8	-0.3
Sensitivity / hurt feelings	0.5	0.9	3.2	-1.4	-0.4	-1.3	-1.0	-0.8	-0.8	-0.7	1.8	-0.9	-0.4	-0.6	-0.1	-1.1	-0.4	-0.8
Frequency of depressed mood in last 2 weeks	1.6	2.2	9.0	-0.4	-1.6	-0.9	-1.8	-1.6	-1.4	-1.3	3.0	-1.1	-1.2	-1.4	-1.0	-1.6	-1.1	-1.4
Hearing difficulty/problems: Yes	0.1	0.2	1.6	1.3	-0.4	-0.6	-0.2	-0.1	0.1	0.4	-0.6	0.4	-0.2	-0.2	0.2	0.5	-0.0	-0.3
Relative age of first facial hair	2.3	4.7	7.5	1.0	-2.3	-1.9	-2.6	-2.7	-2.4	-2.5	1.1	-2.4	-2.4	-2.5	-2.2	-1.1	-2.6	-1.8
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	4.4	-2.1	1.0	0.2	1.3	0.5	1.4	0.9	0.9	0.5	1.2	1.2	1.7	-0.5	1.0	1.9
Ever used hormone-replacement therapy (HRT)	0.6	0.7	2.4	0.7	1.6	-0.4	0.6	1.0	0.4	1.2	-0.9	0.5	0.8	0.6	1.1	1.0	0.8	0.3
Ever had hysterectomy (womb removed)	6.7	7.6	11.5	0.6	-2.4	-2.8	-3.1	-3.4	-2.9	-3.0	2.2	-3.0	-3.1	-2.8	-2.4	-3.1	-2.5	-3.1
Systolic blood pressure, automated reading	1.4	4.1	5.8	2.0	-1.8	-2.3	-1.9	-1.7	-2.0	-1.8	1.4	-2.1	-2.4	-2.4	-2.3	-1.6	-2.1	-2.1
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	3.4	1.9	-1.2	-0.5	-0.4	-0.1	-1.2	-0.9	1.2	-0.4	-0.8	-1.1	-0.9	0.1	-1.0	-1.0
Angina	0.4	0.5	1.1	-0.9	0.7	0.8	0.5	0.3	0.6	0.9	0.7	0.8	0.7	0.8	0.9	0.3	1.0	0.7
Medication for hormone replacement therapy	0.7	0.8	4.0	-0.7	0.3	-1.2	-0.1	-0.7	-0.6	-0.5	2.0	-1.1	-0.2	-0.3	-0.1	-1.9	-0.0	0.4
Vitamin and mineral supplements	1.7	2.3	5.2	-1.6	1.5	2.3	1.2	1.5	1.3	1.2	-1.4	1.3	1.7	1.8	1.5	1.8	1.3	0.4
Supplements: Zinc	0.7	0.7	2.3	0.9	-0.0	0.8	0.3	1.0	1.5	1.2	-0.0	1.3	0.6	0.7	0.7	0.8	0.8	-0.3
Medication: Co-codamol	2.7	3.1	6.0	0.4	-1.6	-2.1	-1.6	-2.0	-1.4	-1.5	2.4	-2.1	-1.9	-2.0	-1.2	-2.4	-1.5	-1.3
Medication: Metformin	6.4	9.0	23.6	1.4	-2.9	-2.2	-3.0	-2.6	-2.5	-2.8	4.9	-3.0	-2.7	-3.0	-2.7	-3.9	-2.7	-3.5
Diabetes (father)	1.9	2.3	4.6	0.4	-1.4	-1.8	-1.0	-1.8	-2.1	-2.1	0.7	-1.9	-1.7	-1.6	-1.5	-1.6	-1.6	-0.0
Diabetes (mother)	1.0	1.3	3.9	-0.1	-0.9	-0.7	-1.3	-1.6	-0.7	-0.8	0.2	-1.3	-1.3	-1.3	-1.0	-0.5	-1.4	-2.0
Severe depression (siblings)	1.4	1.5	5.3	-2.3	0.9	0.5	1.2	0.3	1.5	1.3	-0.8	1.1	1.2	1.3	1.2	1.1	1.3	1.5
Pack years adult smoking proportion	0.9	1.3	3.8	1.3	-1.1	-1.2	-1.0	-1.2	-1.4	-1.2	2.0	-0.8	-1.2	-0.9	-0.9	-1.4	-0.5	-0.5
Impedance of leg (right)	1.5	7.1	12.0	2.6	-3.2	-1.9	-2.8	-2.8	-3.5	-3.0	2.3	-2.3	-2.9	-2.8	-2.9	-0.2	-2.8	-2.5
Leg fat-free mass (left)	6.0	31.6	51.7	-3.5	7.2	4.0	6.4	5.6	6.6	6.8	-4.0	4.8	6.1	5.8	6.1	2.2	6.6	6.1
Trunk fat percentage	0.6	2.5	8.0	-1.8	0.8	-2.8	-0.1	-1.8	-0.7	-0.7	2.5	-2.5	-0.9	-0.8	-0.1	-2.8	-0.3	-0.3
Hand grip strength (right)	0.3	0.9	2.0	0.8	1.4	0.7	1.1	0.2	1.0	1.2	-1.2	0.7	0.7	0.6	1.0	-0.4	1.4	0.7
Townsend deprivation index at recruitment	0.5	0.8	2.7	0.0	-1.1	-0.2	-1.2	-0.7	-1.3	-1.1	1.6	-0.2	-0.9	-0.6	-0.7	-0.4	-0.5	-0.5
Current tobacco smoking	2.4	3.9	7.7	0.8	-2.4	-1.7	-2.0	-2.4	-1.9	-1.8	2.8	-1.4	-2.0	-1.8	-1.8	-2.7	-1.1	-2.4
Average weekly fortified wine intake	0.1	0.1	0.9	-0.9	0.4	0.3	0.3	-0.3	0.5	0.3	-0.1	0.1	0.2	0.2	0.1	0.6	0.4	-0.0
Maternal smoking around birth	2.2	3.1	8.7	2.9	-2.3	0.0	-1.7	-1.4	-1.3	-1.8	0.9	-0.9	-2.2	-1.9	-1.8	-1.8	-1.8	-1.6
Fed-up feelings	6.4	11.5	20.2	0.3	-3.6	-3.0	-3.4	-3.7	-3.4	-3.5	4.5	-3.7	-3.4	-3.8	-3.2	-3.9	-3.2	-2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	2.7	3.6	6.7	-0.6	-2.0	-1.5	-2.2	-2.0	-0.9	-1.7	2.6	-2.1	-1.8	-1.9	-1.4	-2.6	-1.9	-2.0
Relative age voice broke	1.9	2.9	5.3	2.3	-1.4	-2.0	-1.6	-1.5	-2.0	-1.8	0.1	-1.8	-2.0	-2.0	-2.0	-1.0	-1.8	-0.4
Taking other prescription medications	1.6	2.5	9.2	-0.2	-1.0	-1.5	-1.3	-1.1	-1.4	-1.6	3.0	-2.2	-1.3	-1.3	-1.0	-2.5	-1.2	-1.0
Age when periods started (menarche)	0.3	0.8	2.3	1.5	-1.2	0.3	-0.3	-0.5	-1.1	-0.7	1.4	-0.3	-1.1	-0.7	-1.1	-0.1	-0.8	-0.5
Bilateral oophorectomy (both ovaries removed)	6.8	7.9	12.0	0.6	-2.2	-2.6	-3.3	-3.5	-2.7	-2.9	2.8	-3.1	-2.9	-2.9	-2.5	-3.2	-2.6	-3.2
Heel bone mineral density (BMD) T-score, automated (left)	5.1	11.6	16.8	1.8	-3.7	-3.3	-3.0	-3.4	-3.5	-4.1	2.7	-3.8	-4.0	-3.4	-3.4	-3.5	-3.9	-2.9
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.9	-1.7	0.7	0.7	0.9	0.9	1.0	0.5	0.8	0.3	1.0	1.0	0.6	-0.1	0.5	1.4
Qualifications: CSEs or equivalent	2.3	3.1	4.8	1.6	-1.7	-1.6	-1.1	-1.9	-2.2	-1.9	0.5	-1.9	-1.9	-2.1	-2.0	-1.4	-1.9	-2.1
Serious illness, injury or assault to yourself	1.9	2.3	5.9	-1.1	1.7	0.7	2.0	1.6	1.4	1.6	-1.7	1.0	1.5	1.5	1.8	0.1	1.5	2.4
High blood pressure	1.6	4.5	11.9	-1.4	-1.2	-3.1	-2.1	-2.0	-2.2	-1.9	3.5	-2.7	-1.6	-1.6	-1.4	-2.2	-1.6	-1.9
Hayfever, allergic rhinitis or eczema	8.3	18.0	31.1	1.0	-3.8	-4.3	-4.7	-5.6	-4.3	-5.0	2.3	-5.0	-4.4	-4.6	-3.9	-4.2	-4.6	-3.8
Multivitamins +/- minerals	0.9	1.2	2.3	1.3	-1.3	-1.5	-0.7	-1.3	-0.6	-0.8	0.4	-0.8	-1.5	-1.4	-1.1	-1.4	-1.0	0.2
Stomach or abdominal pain in last month	1.1	1.4	3.9	-1.2	-1.1	-2.0	-0.7	-1.4	-1.0	-1.2	1.3	-1.4	-0.9	-0.8	-0.6	-1.8	-0.6	-1.0
Supplements: Glucosamine	4.1	5.4	7.4	1.7	-2.3	-2.5	-2.5	-2.7	-2.5	-2.6	1.3	-2.3	-2.6	-2.6	-2.2	-2.2	-2.4	-1.9
Diverticular disease/diverticulitis (self-reported)	2.3	2.8	5.7	-0.5	-1.2	-2.4	-2.1	-1.7	-1.4	-1.8	1.0	-2.4	-1.5	-1.6	-1.6	-1.4	-1.7	-1.7
Medication: Atenolol	0.2	0.2	1.3	0.2	0.1	1.2	-0.0	0.7	0.3	0.4	0.0	0.8	0.4	0.5	0.1	-0.5	0.4	-0.2
Medication: Levothyroxine sodium	3.4	5.8	15.2	-3.9	2.8	2.0	2.1	2.0	2.5	2.2	1.1	1.6	2.9	3.0	3.0	1.3	2.6	1.3
Sitting height	23.3	165.4	222.0	-6.0	13.7	12.2	13.4	13.8	14.8	14.9	-10.2	13.3	14.2	13.8	13.4	9.9	13.8	12.5
Chronic bronchitis/emphysema (father)	1.5	1.7	9.2	-0.0	-1.3	0.0	-1.1	-1.3	-1.0	-1.6	3.0	-1.3	-0.9	-0.7	-0.6	-2.2	-0.7	-0.4
High blood pressure (mother)	0.1	0.1	0.9	-0.4	-0.0	-0.9	-0.0	-0.4	0.4	0.2	0.7	-0.3	-0.0	-0.1	-0.0	0.2	-0.1	-0.3
Body mass index (BMI)	1.1	4.5	19.4	-2.0	0.3	-3.7	-0.8	-2.3	-0.8	-1.1	2.7	-3.0	-1.6	-1.3	-0.5	-4.4	-0.7	-1.0
Impedance of leg (left)	2.4	11.4	17.2	2.6	-4.0	-2.5	-3.6	-3.6	-4.1	-3.9	3.2	-3.1	-3.7	-3.6	-3.6	-0.8	-3.7	-3.2
Leg predicted mass (left)	5.9	31.4	51.4	-3.5	7.2	4.0	6.3	5.6	6.6	6.8	-3.9	4.8	6.1	5.8	6.1	2.2	6.6	6.0
Trunk fat mass	0.6	2.6	8.3	-2.6	2.9	-1.3	1.7	0.2	1.6	1.5	0.7	-0.7	1.1	1.1	1.8	-1.8	1.7	1.4
Waist circumference	0.5	1.8	7.5	0.2	-0.2	-1.8	-1.0	-1.3	-0.3	-0.4	2.2	-1.7	-1.3	-1.4	-0.5	-2.7	-0.5	-1.0
Number of incorrect matches in round	0.8	1.3	5.6	1.7	-1.4	-1.1	-1.1	-0.7	-0.3	-0.7	0.0	-0.6	-1.4	-1.1	-1.1	-2.4	-0.7	-0.9
Past tobacco smoking	2.4	4.4	8.7	0.2	-1.3	-2.9	-1.4	-2.3	-2.6	-2.2	2.8	-2.8	-2.1	-2.3	-2.2	-1.2	-2.0	-0.8
Alcohol usually taken with meals	3.6	5.8	10.2	-3.2	2.7	2.2	1.6	2.2	2.6	2.5	-2.3	2.1	2.8	2.6	2.8	2.0	2.4	1.3
Nervous feelings	0.3	0.5	4.1	-2.0	0.0	0.4	0.1	-0.1	0.2	-0.0	0.9	0.1	0.6	0.4	0.4	1.4	0.1	0.2
Frequency of tenseness / restlessness in last 2 weeks	3.5	5.4	16.5	-0.5	-2.5	-2.2	-2.5	-2.5	-2.6	-2.3	4.1	-2.2	-2.1	-2.2	-1.8	-2.5	-1.7	-1.7
Hearing difficulty/problems with background noise	4.1	6.5	11.6	-2.4	1.9	2.1	2.4	2.3	3.4	3.0	-1.4	2.9	2.9	2.9	3.0	2.2	2.7	1.8
Hair/balding pattern: Pattern 2	0.9	1.1	3.1	1.8	-1.5	-0.1	-1.0	-0.8	-1.5	-1.4	0.1	-0.4	-1.0	-1.0	-0.8	-0.3	-1.4	-0.9
Had menopause	8.8	11.0	16.5	-2.2	3.6	2.7	3.3	3.0	4.0	4.1	-3.2	3.4	3.5	3.3	3.6	3.2	3.3	3.0
Had other major operations	0.7	0.9	4.6	-2.1	0.8	0.8	0.5	0.6	1.0	0.6	-0.4	0.3	1.1	1.0	1.4	0.6	0.3	0.7
Forced vital capacity (FVC)	0.3	1.2	5.1	0.0	1.9	1.0	1.1	0.2	0.9	1.0	-2.2	0.2	0.7	0.9	0.6	0.3	1.2	1.5
Heel bone mineral density (BMD) T-score, automated (right)	4.8	11.0	14.4	1.5	-3.7	-3.1	-2.8	-3.5	-3.4	-3.8	3.5	-3.4	-3.7	-3.1	-3.4	-3.6	-3.5	-3.0
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.7	-0.1	-1.3	-0.0	-0.9	-1.2	-0.4	-1.0	0.2	-0.7	-0.9	-1.1	-1.1	-0.3	-1.2	-0.5
Qualifications: None of the above	16.3	34.8	49.6	4.5	-7.0	-4.7	-6.5	-6.0	-6.1	-6.0	5.5	-5.0	-6.5	-6.6	-6.0	-4.8	-5.9	-6.6
Financial difficulties in last 2 years	2.7	3.6	9.2	-1.3	-1.2	-3.0	-1.3	-2.7	-2.5	-2.0	2.0	-2.2	-1.7	-1.7	-0.9	-2.3	-1.0	-0.6
Mouth/teeth dental problems	0.2	0.3	1.7	-0.0	0.4	-1.3	0.5	-0.4	-0.1	-0.3	-0.1	-0.4	-0.2	0.1	-0.2	-1.1	-0.0	0.0
Heart attack	0.2	0.3	1.1	0.7	-0.6	0.2	-1.1	-0.2	-0.3	-0.6	-0.4	-0.4	-0.7	-0.7	-0.4	-0.4	-0.6	-0.5
Allergy	12.1	27.8	44.2	-1.7	5.4	5.2	5.4	6.7	5.8	6.2	-3.6	5.8	5.7	5.9	5.0	4.5	5.7	4.6
Pain all over the body in last month	1.0	1.1	2.3	1.5	-1.2	-1.0	-1.2	-0.8	-0.8	-0.8	0.7	-0.7	-1.0	-1.3	-1.1	-1.3	-0.8	-1.0
Diabetes (self-reported)	3.5	5.4	18.0	1.1	-2.0	-1.5	-2.4	-2.0	-1.8	-2.0	4.2	-2.4	-2.1	-2.3	-2.0	-3.2	-1.9	-2.3
Hayfever/allergic rhinitis (self-reported)	4.0	5.3	11.1	-1.2	-1.9	-2.3	-2.3	-2.5	-1.8	-2.7	1.8	-3.3	-2.1	-2.2	-1.5	-3.2	-2.7	-1.7
Medication: Ramipril	0.7	0.9	4.3	-0.4	-0.8	-1.0	-1.0	-0.6	-0.8	-1.1	2.1	-0.9	-0.5	-0.4	-0.5	-1.4	-0.3	-0.2
Medication: Simvastatin	0.7	1.0	6.2	0.0	-0.5	-0.3	-1.4	-0.5	-0.7	-0.7	2.5	-1.3	-0.5	-0.8	-0.5	-1.4	-0.6	-0.9
Fluid intelligence score	8.5	17.6	24.5	-3.3	4.4	3.9	4.2	4.4	4.6	4.4	-2.5	4.2	4.6	5.0	4.9	2.9	4.8	4.0
Illnesses of siblings	1.3	1.9	6.4	-0.0	1.1	2.5	1.4	1.4	0.9	1.0	-1.8	1.2	1.4	1.3	0.6	1.4	1.0	1.5
Neuroticism score	2.6	5.4	18.2	-2.0	-2.2	-2.1	-2.3	-2.5	-2.3	-2.4	4.3	-2.3	-1.9	-2.1	-1.5	-2.0	-1.8	-2.1
Weight	3.1	15.3	32.7	-3.7	5.7	1.5	4.5	3.2	4.9	4.9	-1.8	2.4	4.1	4.0	4.7	0.2	4.7	4.0
Impedance of arm (right)	0.1	0.4	3.4	0.9	-0.1	0.4	0.3	-0.4	-0.8	-0.3	0.2	0.0	0.1	-0.1	-0.3	1.8	-0.3	-0.1
Arm fat percentage (right)	1.3	5.1	15.5	-1.6	0.2	-3.9	-1.0	-2.9	-1.6	-1.6	2.6	-3.5	-1.8	-1.7	-0.9	-3.9	-1.2	-1.5
Trunk fat-free mass	8.8	50.5	75.9	-3.6	8.3	5.7	7.6	7.6	8.4	8.7	-5.9	6.8	7.6	7.3	7.6	3.9	8.0	7.1
Hip circumference	3.8	16.3	33.2	-4.6	5.8	1.1	5.0	2.8	4.9	4.6	-1.2	2.4	4.0	4.4	4.7	0.1	4.9	4.7
Time employed in main current job	0.2	0.3	1.3	0.5	-0.3	0.4	0.4	-0.0	0.8	0.2	1.2	0.1	-0.4	-0.0	-0.1	-1.1	0.0	0.1
Alcohol intake versus 10 years previously	5.6	8.4	14.4	2.5	-3.0	-2.9	-2.5	-2.4	-3.8	-3.4	2.1	-3.0	-3.4	-3.4	-2.7	-2.5	-3.1	-2.1
Father’s age at death	9.1	12.2	23.4	-0.5	3.0	2.5	3.3	3.6	3.8	3.8	-4.8	4.1	3.4	3.6	2.9	4.3	3.2	3.5
Worrier / anxious feelings	1.5	2.8	4.8	0.6	-1.8	-1.5	-1.9	-1.7	-2.1	-1.8	1.2	-1.7	-1.6	-2.2	-1.8	-1.0	-1.8	-1.7
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.4	14.6	-2.1	-1.6	-1.8	-1.5	-2.2	-1.0	-1.5	3.8	-1.8	-1.4	-1.5	-0.8	-1.9	-1.3	-1.6
Falls in the last year	1.1	1.5	8.7	-3.0	1.4	0.2	0.9	0.4	0.7	0.8	0.5	0.6	1.2	1.2	1.6	0.3	1.4	1.3
Hair/balding pattern: Pattern 3	0.1	0.2	1.0	-0.5	0.5	-1.0	0.2	0.0	-0.1	0.1	0.6	-0.2	-0.1	-0.0	0.3	-0.4	0.2	-0.0
Number of live births	0.4	0.6	1.7	0.3	0.9	0.9	1.1	0.4	0.5	0.9	-1.1	0.8	0.5	0.7	0.2	1.3	0.6	0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.4	0.7	0.8	-0.2	0.1	-0.6	-0.1	-0.1	-1.2	-1.0	-0.3	-0.2	-0.5	-0.8	0.1	0.7
Pulse rate	0.3	0.5	2.4	-0.1	1.1	-1.6	0.1	0.2	1.0	0.8	-0.5	-0.9	-0.1	-0.2	-0.0	-0.9	-0.1	0.5
Happiness	0.5	0.6	2.3	-1.5	0.4	0.8	0.7	0.7	0.3	0.5	0.9	0.6	1.0	0.9	0.6	-0.1	0.7	0.6
Noisy workplace	6.7	8.2	13.3	3.0	-3.6	-2.1	-2.9	-2.5	-2.6	-2.8	2.8	-2.2	-3.1	-3.4	-3.0	-3.4	-2.9	-2.1
Qualifications: A levels/AS levels or equivalent	19.0	42.2	57.8	-5.4	7.1	5.3	6.6	6.6	7.2	7.0	-4.6	6.2	7.5	7.6	7.1	5.9	6.8	5.7
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	1.4	-0.9	0.4	0.4	0.8	0.3	0.3	0.2	0.7	0.1	0.4	0.7	0.5	-1.2	0.4	0.6
Mouth/teeth dental problems: Dentures	0.0	0.1	0.4	-0.2	-0.1	-0.1	-0.7	0.2	-0.2	0.1	0.1	0.1	-0.2	-0.2	0.4	0.1	-0.0	-0.5
Asthma	4.1	8.1	12.2	0.8	-3.4	-2.1	-2.9	-3.5	-2.9	-3.3	3.0	-2.9	-3.2	-3.2	-2.6	-2.2	-3.2	-2.2
Medication: Ibuprofen (e.g. Nurofen)	2.8	3.6	5.7	0.6	-2.1	-1.4	-2.1	-2.3	-1.6	-2.0	2.1	-2.0	-1.7	-2.1	-1.8	-2.4	-1.7	-1.9
Medication: Cholesterol lowering	0.4	0.7	5.2	-1.0	0.3	-0.5	-0.3	0.0	0.4	0.2	2.3	-0.7	0.0	0.2	0.4	-1.4	0.3	-0.5
Depression (self-reported)	4.3	5.2	7.8	0.9	-2.8	-1.9	-2.2	-2.6	-2.1	-2.1	2.7	-2.0	-2.4	-2.8	-2.1	-2.2	-2.2	-2.5
Medication: Lansoprazole	5.6	6.4	8.9	2.2	-2.8	-2.4	-3.0	-1.9	-2.7	-2.8	1.2	-2.6	-2.4	-2.9	-2.3	-2.2	-3.0	-2.9
Prospective memory result	0.7	0.8	2.2	1.5	-0.7	-1.3	-0.6	-1.1	-0.8	-0.4	0.6	-0.8	-1.0	-1.2	-0.8	-0.4	-0.7	-0.9
Lung cancer (father)	0.3	0.4	1.9	0.9	-0.4	0.1	-0.1	1.4	1.0	0.6	-0.4	1.0	0.7	0.1	0.2	0.1	-0.1	0.1
Illnesses of mother	0.9	1.1	3.4	1.8	-0.7	0.5	-1.1	-0.3	-0.9	-1.0	1.2	-0.7	-0.7	-0.9	-1.4	-1.8	-0.5	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	1.8	1.3	0.8	-0.1	0.0	-0.5	0.1	-0.1	-0.6	-0.7	-0.3	-0.1	-0.4	-1.0	0.4	0.4
Pulse wave Arterial Stiffness index	2.4	2.7	5.0	-1.2	1.9	2.2	1.2	2.1	2.2	2.0	-1.6	1.1	1.9	1.7	1.5	0.6	1.5	0.9
Impedance of arm (left)	0.1	0.5	3.7	0.8	-0.3	0.5	0.2	-0.6	-1.2	-0.6	0.6	0.0	0.0	-0.1	-0.4	1.9	-0.3	-0.3
Arm fat mass (right)	0.5	2.1	6.1	-2.5	2.4	-1.9	1.3	-0.4	1.0	0.9	0.8	-1.2	0.5	0.5	1.3	-2.4	1.2	0.9
Trunk predicted mass	8.9	50.9	76.9	-3.6	8.4	5.7	7.7	7.7	8.5	8.8	-5.8	6.8	7.7	7.4	7.6	3.9	8.0	7.0
Standing height	12.3	121.9	169.0	-3.5	11.7	11.0	11.5	11.9	12.3	13.0	-9.7	11.7	11.9	11.3	11.2	9.5	11.6	10.7
Length of working week for main job	1.2	1.3	3.6	0.5	-0.7	-1.9	-0.4	-0.8	-1.9	-1.1	-0.2	-1.5	-1.1	-1.1	-0.8	-1.8	-0.8	0.0
Exposure to tobacco smoke at home	0.2	0.2	1.1	1.1	-0.0	0.0	-0.4	0.1	0.3	0.2	0.6	0.1	-0.1	-0.3	0.3	0.6	-0.1	-0.8
Breastfed as a baby	11.1	13.8	17.8	-1.5	3.5	4.0	3.6	4.2	4.2	4.1	-3.6	4.1	4.0	4.1	3.7	3.5	3.6	2.9
Tense / ‘highly strung’	3.4	5.7	8.7	0.3	-2.9	-1.3	-2.7	-3.0	-2.7	-2.8	2.8	-2.1	-2.6	-2.6	-2.4	-1.7	-2.3	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	4.3	6.6	10.6	0.8	-3.3	-2.1	-2.6	-2.9	-3.0	-2.8	1.8	-2.1	-2.9	-3.0	-2.5	-1.7	-2.9	-3.1
Hair/balding pattern: Pattern 4	1.2	2.8	5.0	-0.7	1.3	1.5	1.8	2.0	2.2	1.8	-1.4	1.7	1.7	1.8	1.7	1.9	1.5	1.5
Birth weight of first child	0.2	0.3	1.1	-0.5	0.5	1.0	-0.3	1.0	0.3	0.2	0.3	0.4	0.9	0.6	0.5	-0.4	0.5	-0.4
Peak expiratory flow (PEF)	0.4	1.0	3.1	-0.7	1.3	1.8	0.9	0.7	1.0	1.1	-0.4	0.3	1.3	0.8	1.1	0.5	0.9	0.7
Pulse wave reflection index	0.5	0.6	3.2	0.1	-0.4	0.6	-0.6	-0.6	-0.7	-0.5	-0.1	-0.9	-0.6	-0.6	-0.8	0.4	-0.9	-1.8
Ever highly irritable/argumentative for 2 days	7.4	8.9	12.5	1.9	-3.0	-2.6	-3.4	-3.2	-3.1	-3.0	2.2	-3.0	-3.4	-3.4	-3.1	-2.4	-3.0	-3.5
Loud music exposure frequency	0.3	0.3	1.7	-0.7	-0.7	0.2	-0.8	-0.8	-0.3	-0.8	0.4	-0.2	-0.0	-0.2	-0.2	0.0	-0.5	-1.3
Qualifications: O levels/GCSEs or equivalent	20.3	32.3	43.2	-2.8	6.1	5.3	6.5	6.6	5.6	5.9	-4.1	5.6	6.2	6.4	5.8	5.7	5.7	5.9
Mouth/teeth dental problems: Bleeding gums	2.8	3.7	6.7	-2.5	1.8	1.8	2.1	1.0	1.7	2.0	-1.6	1.4	1.8	1.8	2.0	2.6	1.8	2.3
Blood clot in the leg (DVT)	5.6	7.2	11.7	2.4	-3.1	-2.8	-2.2	-2.6	-3.4	-3.1	1.3	-2.2	-3.0	-3.1	-3.2	-2.2	-2.8	-2.2
Medication: Paracetamol	5.0	8.2	12.1	0.6	-2.9	-2.6	-2.8	-3.5	-3.5	-3.4	1.9	-3.5	-2.9	-3.3	-2.8	-1.7	-3.4	-2.7
Headache pain in last month	0.2	0.4	2.0	-1.4	-0.3	-0.1	-0.3	-0.2	-0.5	-0.4	0.4	-0.1	0.1	-0.0	0.1	1.1	-0.5	-1.1
Medication for cholesterol, blood pressure or diabetes	1.6	2.6	9.3	-0.1	1.4	1.4	1.8	1.1	1.1	1.6	-3.0	2.0	1.4	1.3	1.1	1.8	1.5	1.8
Glaucoma (self-reported)	6.3	7.4	19.8	4.5	-3.2	-2.0	-2.7	-2.7	-2.9	-2.4	0.7	-1.6	-3.0	-3.0	-3.3	-2.8	-2.4	-1.7
Gout (self-reported)	0.2	0.2	1.3	-0.2	0.7	-0.1	0.5	0.3	-0.1	-0.0	-1.1	-0.4	0.5	0.5	0.8	0.3	-0.1	0.1
Hypothyroidism/myxoedema (self-reported)	3.3	6.5	13.3	-3.6	3.1	1.9	2.5	2.4	2.3	2.3	1.1	1.8	3.2	3.2	3.0	2.0	2.6	2.1
Medication: Amlodipine	0.3	0.4	2.0	-0.6	0.3	0.5	-0.7	0.4	0.5	0.5	1.4	0.1	0.5	0.3	0.2	-0.6	0.3	-1.1
Medication: Ventolin 100micrograms inhaler	2.7	3.4	7.1	2.1	-1.9	-1.7	-1.6	-1.9	-2.7	-2.1	1.2	-1.5	-2.0	-2.0	-2.1	-0.9	-1.6	-1.6
Birth weight	1.7	3.8	6.5	-0.8	1.9	1.8	1.7	2.4	1.9	2.5	-2.2	2.5	2.3	1.9	1.7	1.8	2.0	1.1
Chronic bronchitis/emphysema (mother)	1.3	1.5	4.7	-1.4	-1.2	-0.6	-1.2	-1.8	-1.3	-1.4	0.9	-0.9	-0.9	-0.8	-0.8	-2.2	-0.6	-1.4
High blood pressure (siblings)	0.2	0.2	1.8	0.1	0.0	-1.3	-0.5	-0.3	-0.2	0.2	0.9	0.1	-0.3	-0.3	0.2	-0.4	0.1	-0.3
Forced vital capacity (FVC), Best measure	0.4	1.3	3.7	0.4	1.9	1.1	1.3	0.3	1.3	1.1	-1.5	0.5	0.8	1.2	0.5	-0.1	1.7	1.6
Body fat percentage	1.3	5.3	15.6	-1.6	0.1	-4.0	-1.1	-2.8	-1.5	-1.6	3.1	-3.5	-1.9	-1.7	-0.8	-3.8	-1.2	-1.3
Leg fat percentage (right)	3.1	11.2	29.3	-1.1	-1.3	-5.4	-2.6	-4.0	-2.5	-2.8	3.7	-4.7	-3.3	-3.1	-2.0	-5.1	-2.4	-2.6
Arm fat-free mass (right)	6.1	31.4	47.2	-3.5	6.8	4.1	6.1	5.8	6.7	6.9	-3.9	5.1	5.9	5.8	6.2	2.3	6.5	5.9
Exposure to tobacco smoke outside home	0.9	1.2	2.8	0.9	-1.1	-1.7	-1.3	-1.0	-1.0	-0.9	0.1	-1.1	-1.4	-1.2	-0.9	-1.0	-1.1	-1.2
Comparative body size at age 10	1.4	3.8	7.8	-2.4	2.2	0.2	1.9	1.6	1.6	2.3	0.8	2.0	2.3	2.0	2.8	1.1	2.7	1.7
Number of full brothers	0.3	0.4	0.8	0.5	-0.8	0.5	-0.3	0.3	-0.8	-0.9	0.8	-0.4	-0.7	-0.5	-0.8	-0.0	-0.8	-0.6
Worry too long after embarrassment	0.3	0.4	4.1	-2.0	0.2	-0.8	-0.0	-0.2	0.0	-0.0	0.5	-0.1	0.2	0.4	0.4	-1.0	0.4	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	2.6	-0.6	-1.0	-1.6	-1.2	-1.6	-1.0	-1.4	1.1	-1.5	-1.1	-1.2	-0.8	-1.5	-1.0	-1.0
Wheeze or whistling in the chest in last year	2.4	4.3	9.9	-0.3	-2.5	-1.4	-1.9	-3.2	-2.3	-2.3	2.9	-1.5	-2.2	-2.1	-1.7	-1.7	-1.6	-1.8
Number of children fathered	2.8	3.1	9.9	-0.7	1.7	1.7	1.6	1.9	2.3	2.3	-3.1	1.5	1.5	1.5	1.8	0.7	1.5	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.8	0.5	0.9	0.1	0.4	0.1	0.5	0.7	-0.4	0.4	0.6	0.5	0.3	-0.2	0.8	0.9
Age at first live birth	2.9	5.1	8.3	-1.1	2.2	1.4	2.2	2.5	2.9	2.8	-2.7	2.2	2.4	2.1	2.0	2.6	2.1	2.0
Pulse wave peak to peak time	0.5	0.5	1.7	0.7	-0.9	-1.3	-0.2	-1.0	-1.1	-0.8	0.8	-0.0	-0.8	-0.7	-0.4	0.2	-0.4	-0.0
Health satisfaction	0.5	0.6	3.0	0.9	-0.8	-1.0	-0.3	-0.3	-0.8	-0.6	0.6	-0.6	-0.8	-0.8	-0.9	-1.7	-0.6	0.1
Shortness of breath walking on level ground	0.5	0.5	2.2	-0.0	-0.6	-0.3	-0.4	-0.7	-0.6	-0.7	1.5	-0.8	-0.4	-0.5	-0.4	-1.2	-0.5	-1.0
Qualifications: College or University degree	10.7	33.7	46.2	-5.6	6.0	5.2	5.8	5.3	6.8	6.0	-4.5	5.1	6.3	6.6	6.5	5.1	5.9	5.8
Eye problems/disorders: None of the above	0.5	0.5	1.4	-0.1	0.9	-0.2	0.7	1.2	0.8	0.7	-1.0	0.7	0.7	0.7	0.9	1.0	0.5	0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.0	-0.7	-0.2	0.4	0.7	0.5	0.0	0.2	-0.5	0.9	0.4	0.5	0.6	0.9	0.5	1.0
Emphysema/chronic bronchitis	0.4	0.5	1.0	0.6	-1.0	-0.6	-0.8	-1.0	-1.0	-0.7	0.8	-0.0	-1.0	-0.7	-0.7	-0.1	-0.3	0.0
Medication for pain relief, constipation, heartburn	8.6	14.6	19.7	-0.9	3.9	3.2	4.1	4.4	4.3	4.3	-3.4	4.4	4.0	4.4	3.4	2.9	4.2	3.9
Neck or shoulder pain in last month	1.1	1.6	7.0	-1.0	-1.4	0.0	-1.5	-1.0	-1.3	-1.4	2.6	-0.8	-0.6	-0.8	-0.4	-1.8	-0.9	-1.3
Medication: Blood pressure	1.0	1.8	5.1	0.5	-1.2	-1.1	-1.7	-0.7	-1.2	-1.6	2.3	-1.7	-1.1	-1.0	-0.9	-1.3	-1.4	-1.4
Angina (self-reported)	0.6	0.8	1.4	-1.2	0.8	1.0	0.7	0.5	0.9	1.0	0.7	0.9	0.9	1.0	1.2	0.3	1.2	0.9
Migraine (self-reported)	0.4	0.5	1.7	-0.6	0.3	-0.9	-0.7	-0.5	-1.2	-0.9	0.8	-1.3	-0.5	-0.4	-0.4	-0.4	-0.5	-0.0
Medication: Ibuprofen	0.4	0.5	2.0	-0.4	-0.8	-0.3	-0.7	-0.7	-0.2	-0.6	1.4	-0.7	-0.3	-0.6	-0.2	-1.3	-0.3	-0.9
Medication: Allopurinol	0.2	0.2	0.8	0.1	0.4	0.7	0.3	0.5	-0.1	-0.1	-0.9	0.2	0.5	0.5	0.6	0.7	0.1	0.3
Medication: Omeprazole	3.3	3.9	8.0	-0.2	-1.8	-1.5	-2.0	-2.1	-1.7	-2.1	2.5	-2.8	-1.9	-1.9	-1.8	-2.1	-2.1	-2.1
Medication: Seretide 50 evohaler	0.4	0.5	3.5	-1.9	-0.4	-0.6	-0.3	-1.3	-0.7	-0.5	-0.0	-0.4	-0.4	-0.3	0.6	-0.3	-0.2	0.4
Mean time to correctly identify matches	0.9	1.6	2.6	0.1	-1.3	-1.5	-1.3	-1.0	-1.3	-1.6	1.4	-1.4	-1.3	-1.0	-1.1	-1.3	-1.6	-1.3
Heart disease (mother)	2.9	3.5	6.6	-2.3	2.0	0.1	2.0	1.6	2.4	2.3	-0.3	1.4	1.5	2.2	2.6	0.3	2.4	2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	2.9	0.0	0.5	0.3	0.6	-0.1	0.1	0.1	-1.3	-0.1	0.3	0.0	0.2	1.7	-0.4	0.8
Whole body fat mass	0.5	2.1	6.3	-2.4	2.3	-1.9	1.1	-0.5	1.0	0.9	1.3	-1.4	0.4	0.5	1.3	-2.5	1.1	0.9
Leg fat mass (right)	0.7	2.7	12.5	-2.0	1.3	-3.2	-0.0	-1.6	0.0	-0.2	1.8	-2.4	-0.8	-0.7	0.2	-3.5	0.1	-0.0
Arm predicted mass (right)	5.8	29.8	45.0	-3.3	6.7	4.1	5.9	5.8	6.6	6.7	-3.6	4.9	5.8	5.7	6.1	2.4	6.3	5.6
Pulse rate, automated reading	0.7	2.3	7.4	0.1	-0.1	-2.7	-0.9	-1.2	-0.1	-0.5	2.7	-2.3	-1.1	-1.4	-0.7	-2.0	-1.1	-1.6
Alcohol intake frequency.	7.7	18.0	23.8	2.8	-4.0	-4.4	-4.3	-3.9	-4.9	-4.6	3.5	-4.6	-4.7	-4.6	-4.7	-3.8	-4.2	-4.1
Comparative height size at age 10	14.9	82.0	114.5	-4.6	9.7	9.0	9.2	9.8	10.2	10.7	-7.7	9.2	10.2	9.4	9.4	7.9	9.4	7.7
Number of full sisters	0.1	0.1	0.5	0.7	-0.2	0.0	-0.2	-0.2	-0.2	0.1	-0.5	0.4	-0.2	-0.0	-0.7	0.1	-0.1	-0.1
Suffer from ‘nerves’	0.9	1.3	5.4	-0.9	-0.9	-1.3	-0.8	-1.1	-1.7	-1.2	2.3	-1.3	-0.7	-1.2	-0.6	-0.9	-0.7	-0.5
Overall health rating	1.8	3.8	12.3	-0.1	-1.7	-2.2	-1.5	-1.7	-2.1	-1.9	3.5	-2.0	-1.8	-1.9	-1.2	-2.9	-1.3	-1.2
Chest pain or discomfort	0.3	0.4	1.9	0.1	-0.1	0.7	0.7	0.0	0.5	0.8	0.1	1.4	0.4	0.4	0.6	0.6	0.9	0.8
Had major operations	0.9	1.0	2.6	-1.6	1.5	0.5	0.9	0.9	1.0	0.9	-0.2	0.6	1.1	1.5	1.1	0.4	1.2	0.6
Age at last live birth	3.8	5.4	8.0	-0.7	2.4	1.4	2.4	2.6	2.8	2.8	-2.6	2.4	2.4	2.5	2.1	2.2	2.4	2.3
Family relationship satisfaction	0.1	0.2	0.8	0.4	0.1	0.2	0.3	0.9	-0.1	0.0	0.0	0.5	0.3	0.4	-0.3	-0.4	0.2	0.8
Leg pain on walking	1.9	2.4	4.3	0.3	-1.7	-2.1	-1.7	-1.8	-1.7	-1.7	0.2	-1.6	-1.9	-1.6	-1.3	-1.9	-1.4	-0.9
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	3.8	-0.1	-0.5	-1.3	-1.0	-1.3	-1.7	-1.6	1.2	-2.0	-1.1	-1.4	-1.2	-1.2	-1.2	-0.4
Commuting to job workplace: Car/motor vehicle	2.4	2.8	4.8	1.4	-1.3	-1.8	-1.3	-1.5	-2.2	-2.0	0.7	-1.9	-1.8	-1.9	-1.7	-2.1	-1.7	-0.9
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	3.9	0.3	0.7	1.3	0.2	1.6	1.4	0.8	-1.4	1.0	1.0	0.9	0.7	2.0	0.3	-0.0
Medication: Aspirin	0.2	0.2	1.1	-0.0	-0.3	-0.5	-1.0	-0.2	-0.6	-0.4	0.2	-0.6	-0.3	-0.6	-0.1	0.1	-0.5	-0.5
Supplements: Vitamin C	1.8	2.2	3.7	1.1	-1.5	-1.9	-1.5	-1.7	-1.5	-1.5	1.7	-1.3	-1.6	-1.5	-1.4	-1.5	-1.3	-0.8
Knee pain experienced in last month	6.5	10.1	16.2	0.1	-3.2	-3.3	-3.6	-4.0	-3.2	-3.4	2.4	-3.5	-3.4	-3.5	-2.1	-3.9	-3.1	-2.9
Hypertension (Self-reported)	1.9	5.2	13.9	-1.4	-1.2	-3.0	-2.4	-2.2	-2.2	-2.1	3.7	-2.9	-1.7	-1.8	-1.5	-2.3	-1.8	-2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.7	4.3	6.1	1.5	-2.2	-2.1	-2.3	-1.7	-2.5	-2.3	0.8	-2.3	-2.1	-2.4	-2.2	-1.1	-2.5	-2.4
Illnesses of father: Heart disease	1.3	1.8	4.6	-1.1	1.5	1.1	1.4	1.7	2.1	1.6	-0.4	0.8	1.2	1.3	1.6	0.3	1.4	1.1
Illnesses of siblings: Diabetes	3.5	4.3	10.0	2.0	-2.5	-2.3	-2.5	-1.8	-1.5	-1.6	0.7	-1.6	-2.3	-2.4	-2.3	-1.2	-2.2	-3.2
Smoking status: Previous	2.0	2.9	7.1	1.0	0.9	2.3	1.3	2.0	2.1	1.8	-2.7	2.4	1.4	1.6	1.5	1.4	1.3	0.8
Forced expiratory volume in 1-second (FEV1), predicted	4.0	8.3	11.5	0.1	2.8	2.8	3.3	2.9	2.7	3.0	-2.8	3.2	3.1	2.8	2.6	3.4	3.0	3.3
Whole body fat-free mass	7.6	43.2	64.2	-3.8	8.0	5.0	7.2	6.9	7.8	8.0	-5.0	6.0	7.1	6.8	7.1	3.2	7.5	6.8
Leg fat-free mass (right)	6.3	33.4	51.8	-3.7	7.2	4.3	6.5	5.8	6.9	6.9	-4.0	5.1	6.3	6.0	6.2	2.4	6.7	6.3
Arm fat percentage (left)	1.4	5.7	16.5	-1.8	0.1	-4.1	-1.1	-3.0	-1.7	-1.8	3.0	-3.7	-1.9	-1.8	-0.9	-4.0	-1.2	-1.6
Average weekly red wine intake	11.0	16.2	24.6	-4.2	4.1	3.9	3.3	3.7	4.8	4.6	-2.7	3.9	5.0	4.4	4.9	3.5	4.1	2.5
Handedness (chirality/laterality): Left-handed	0.9	1.0	2.5	1.3	-1.1	-0.8	-0.7	-0.8	-1.1	-1.3	1.6	-0.9	-1.1	-0.8	-0.8	-1.1	-0.7	-0.4
Mood swings	3.1	5.6	11.1	0.0	-3.0	-1.2	-2.8	-2.0	-2.9	-2.8	3.3	-2.0	-1.8	-2.6	-2.1	-2.0	-2.4	-2.6
Loneliness, isolation	2.0	2.8	8.9	-0.6	-1.4	-1.3	-1.5	-2.0	-1.6	-1.8	3.0	-2.0	-1.4	-1.5	-1.4	-2.0	-1.2	-1.1
Long-standing illness, disability or infirmity	4.9	7.5	15.6	0.0	-2.4	-3.0	-2.7	-2.7	-2.6	-3.0	3.0	-3.3	-2.6	-2.8	-2.1	-4.0	-2.6	-2.2
Ever had bowel cancer screening	1.4	1.6	2.7	-1.2	0.9	1.6	0.8	1.6	1.4	1.2	-0.5	1.4	1.6	1.5	1.6	0.9	1.1	0.7
Diabetes diagnosed by doctor	4.2	7.0	21.7	1.0	-2.1	-2.1	-2.6	-2.3	-2.4	-2.3	4.7	-2.9	-2.4	-2.6	-2.2	-3.8	-2.0	-2.5
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	2.0	-1.2	1.4	0.6	1.0	0.5	1.3	1.0	-1.2	0.4	0.6	1.2	1.1	1.1	0.5	0.3
Friendships satisfaction	0.9	1.1	3.4	-1.8	0.7	0.6	0.9	1.1	1.0	0.9	0.9	1.0	1.4	1.2	1.1	0.3	1.1	0.8
Qualifications: nursing, teaching	13.4	20.8	27.5	-3.4	4.7	4.6	4.3	4.9	5.0	4.9	-2.9	4.5	5.2	5.2	5.2	2.9	4.9	4.7
Commuting to job workplace: Walk	1.1	1.1	7.0	-1.4	-0.4	-1.0	-0.8	-1.3	-0.7	-0.7	2.6	-1.0	-0.7	-0.5	-0.8	-1.0	-0.2	-0.2
Eye problems/disorders: Cataract	0.2	0.2	1.1	-1.1	0.5	0.4	0.5	-0.3	0.2	0.2	-0.1	-0.0	0.2	0.4	0.3	0.5	0.2	1.0
Mouth/teeth dental problems: Mouth ulcers	3.7	5.9	9.4	1.7	-3.1	-0.4	-2.9	-2.0	-2.7	-2.9	2.9	-2.3	-2.3	-2.4	-2.7	-1.5	-2.8	-2.3
Medication for cholesterol	1.8	2.7	6.6	1.0	1.0	2.0	2.0	1.6	1.0	1.3	-2.6	1.9	1.2	1.4	0.4	2.4	1.3	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.7	5.2	-0.5	-1.1	-1.0	-0.8	-2.1	-1.4	-1.2	2.3	-1.2	-1.4	-1.2	-0.5	-2.0	-0.6	-0.5
Back pain experienced in last month	5.6	8.1	11.6	0.5	-3.1	-2.3	-3.0	-3.3	-2.9	-3.4	1.3	-3.2	-3.2	-3.4	-2.6	-3.0	-3.3	-2.4
Mineral and other dietary supplements	0.8	1.0	2.8	-1.7	1.4	0.4	1.4	0.8	0.4	0.9	0.6	0.4	1.2	1.0	1.2	0.1	1.4	0.7
Breast cancer (self-reported)	4.6	5.4	8.3	-2.3	2.3	2.4	2.9	2.2	2.2	2.2	-1.4	2.5	2.5	2.8	2.4	2.4	2.3	2.1
Asthma (self-reported)	5.0	9.9	15.0	0.6	-3.7	-2.3	-3.4	-3.9	-3.2	-3.6	3.4	-3.2	-3.4	-3.5	-2.8	-2.5	-3.5	-2.6
Osteoporosis (self-reported)	0.2	0.2	1.0	-0.6	-0.0	-1.0	0.1	-0.5	-0.8	-0.3	0.8	-0.3	-0.3	-0.3	-0.2	-0.4	0.1	0.0
Osteoarthritis (self-reported)	4.6	6.0	8.4	1.9	-2.8	-2.2	-2.5	-1.9	-2.2	-2.7	1.7	-2.2	-2.9	-2.8	-2.5	-2.6	-2.8	-2.6
Medication: Aspirin	0.1	0.1	0.5	0.1	0.3	0.3	-0.5	0.6	0.2	0.3	-0.3	0.3	0.3	0.1	0.5	0.7	0.2	-0.0
Medication: Gliclazide	2.3	2.6	4.9	1.4	-1.9	-0.6	-1.8	-1.4	-1.4	-1.7	2.0	-1.3	-1.7	-1.6	-1.8	-2.2	-1.5	-1.4
Illnesses of father: None of the above (group 1)	0.4	0.5	2.4	0.6	0.2	0.6	0.2	1.0	0.2	0.8	-1.1	0.9	0.7	0.2	0.3	1.5	0.2	-0.6
Smoking status: Current	2.3	3.6	7.7	0.7	-2.3	-1.5	-2.0	-2.3	-1.8	-1.7	2.8	-1.2	-1.8	-1.7	-1.7	-2.6	-1.0	-2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.1	4.5	7.4	2.3	-1.4	-2.5	-2.2	-2.0	-1.5	-1.8	-0.1	-2.6	-2.4	-2.3	-2.7	-2.2	-2.0	-2.3
Whole body water mass	7.7	44.0	65.2	-3.8	8.1	5.1	7.3	6.9	7.9	8.1	-5.1	6.1	7.1	6.9	7.2	3.2	7.6	6.9
Leg predicted mass (right)	6.2	33.3	51.5	-3.7	7.2	4.3	6.5	5.8	6.9	6.9	-3.9	5.1	6.2	6.0	6.2	2.4	6.7	6.3
Arm fat mass (left)	0.5	2.1	6.6	-2.6	2.4	-1.8	1.3	-0.4	1.0	0.9	0.9	-1.2	0.5	0.6	1.3	-2.3	1.2	0.8
Number of self-reported non-cancer illnesses	4.2	7.3	17.1	-1.3	-2.3	-3.0	-2.5	-3.2	-2.6	-2.8	4.1	-3.1	-2.5	-2.4	-1.6	-3.5	-2.0	-2.3
Average weekly champagne plus white wine intake	1.7	2.3	10.3	-0.7	1.2	1.2	1.2	1.0	2.1	1.6	-3.2	1.5	1.2	1.4	1.2	1.1	1.2	1.3
Miserableness	2.5	4.3	17.0	-1.3	-2.2	-1.6	-1.5	-2.0	-2.7	-2.3	4.1	-1.8	-1.7	-2.0	-1.5	-2.0	-1.4	-1.0
Guilty feelings	0.6	0.9	4.7	-2.2	-0.6	-0.2	-0.6	-0.5	0.1	-0.6	2.0	-0.8	-0.2	0.0	0.2	-1.8	-0.3	-0.4
Wears glasses or contact lenses	4.0	4.6	6.4	-0.8	2.1	2.0	2.2	2.4	2.2	2.5	-1.6	2.5	2.5	2.0	2.2	2.5	2.0	2.0
Ever taken oral contraceptive pill	2.1	2.4	4.5	-0.9	1.4	1.6	2.1	1.7	2.1	1.7	-0.9	1.4	1.6	1.8	1.1	0.5	1.6	1.6
Hearing aid user	0.2	0.3	0.7	0.4	-0.7	-0.6	-0.4	-0.5	-0.1	0.0	-0.5	-0.1	-0.6	-0.8	-0.2	0.8	-0.6	-0.6
Mother’s age at death	1.4	1.7	3.9	-0.3	0.8	2.0	0.6	1.5	1.6	1.2	-1.4	1.7	1.7	1.5	1.3	0.7	1.4	0.7
Financial situation satisfaction	4.8	6.0	9.2	1.9	-2.9	-2.0	-2.4	-2.2	-2.7	-2.4	3.0	-2.0	-2.7	-2.7	-2.5	-2.6	-2.3	-1.9
Tinnitus: Yes, now most or all of the time	4.5	5.3	8.0	1.3	-2.5	-2.4	-1.9	-2.8	-2.6	-2.2	1.7	-2.3	-2.5	-2.8	-2.4	-1.9	-2.3	-2.4
Commuting to job workplace: Public transport	1.4	1.7	3.6	-1.2	1.2	0.7	1.1	0.9	1.5	1.6	-0.5	1.3	1.5	1.4	1.9	1.4	1.5	1.1
Eye problems/disorders: Glaucoma	1.5	1.7	8.5	2.9	-1.5	-0.4	-1.2	-0.8	-1.2	-0.9	-0.3	-0.6	-1.2	-1.3	-1.6	-1.9	-0.9	-0.4
Medication: Blood pressure	1.8	3.4	9.1	-0.7	-1.7	-2.3	-2.5	-2.0	-1.6	-1.5	1.5	-1.7	-1.8	-1.9	-1.0	-1.3	-2.0	-3.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.5	-1.6	0.8	0.3	0.3	0.2	0.4	0.3	1.5	-0.1	0.5	0.4	1.2	-0.9	0.7	0.3
Supplements: Fish oil (including cod liver oil)	0.9	1.2	3.0	1.7	-1.4	-0.2	-1.4	-0.9	-0.4	-0.9	-1.1	-0.3	-1.2	-1.0	-1.5	0.0	-1.6	-1.0
High cholesterol (Self-reported)	2.3	4.1	21.3	-0.2	-2.0	-0.4	-2.2	-1.4	-1.4	-1.7	4.6	-1.8	-1.5	-1.4	-1.2	-3.1	-1.3	-1.8
Medication: Bendroflumethiazide	1.0	1.6	3.5	0.1	-1.1	-1.4	-1.5	-1.1	-1.8	-1.5	0.7	-1.4	-1.0	-1.2	-0.6	-1.2	-1.4	-1.9
Medication: Paracetamol	2.1	3.3	6.6	-0.3	-1.7	-1.6	-1.6	-2.6	-2.4	-2.2	0.9	-2.4	-1.7	-2.0	-1.5	-0.6	-2.2	-1.9
Medication: Lisinopril	3.5	4.5	8.3	1.4	-2.6	-1.5	-2.6	-1.7	-2.2	-2.3	2.3	-1.9	-2.3	-2.0	-1.9	-1.2	-2.2	-2.9
Medication: Atorvastatin	0.6	0.8	2.8	-1.7	0.1	1.4	0.4	0.4	1.0	0.5	1.4	0.9	0.7	0.9	0.9	0.1	0.7	0.3
Illnesses of father: High blood pressure	0.5	0.6	2.2	0.1	-0.5	-0.7	-0.5	-1.5	-1.0	-0.7	1.3	-0.7	-0.9	-0.6	-0.9	0.0	-0.6	0.0
Alcohol drinker status: Never	6.8	8.1	12.9	1.3	-2.2	-3.2	-2.7	-3.2	-3.6	-3.3	1.6	-3.6	-3.4	-3.0	-3.3	-2.6	-2.7	-1.6
Ever smoked	5.4	9.5	15.7	-1.6	2.4	4.0	2.4	3.3	3.6	3.2	-3.6	3.7	3.5	3.6	3.2	1.9	3.2	1.5
Basal metabolic rate	6.6	36.5	57.8	-3.8	7.6	4.3	6.7	6.1	7.2	7.4	-4.3	5.3	6.5	6.3	6.6	2.5	7.0	6.3
Leg fat percentage (left)	3.8	13.6	32.9	-1.0	-1.7	-5.7	-3.1	-4.5	-2.8	-3.3	3.9	-5.1	-3.7	-3.5	-2.4	-5.4	-2.9	-3.1
Arm fat-free mass (left)	6.3	32.2	49.1	-3.4	7.0	4.1	6.2	5.9	6.9	7.0	-3.9	5.1	6.0	5.8	6.3	2.5	6.5	6.0
Number of operations (self-reported)	0.3	0.4	1.1	-1.0	-0.2	-0.3	-0.7	-0.4	-0.8	-0.7	1.0	-0.9	-0.2	-0.2	-0.2	-0.1	-0.7	-0.4
Average weekly beer plus cider intake	0.2	0.3	1.5	1.2	-0.1	-0.9	0.1	0.7	-0.4	-0.1	0.1	-0.0	-0.2	-0.0	-0.6	-1.1	0.1	0.3
Irritability	2.0	3.4	12.3	-1.7	-2.0	-1.1	-1.9	-1.8	-2.3	-2.4	3.5	-1.6	-1.5	-1.2	-1.0	-0.8	-1.3	-1.8
Risk taking	0.4	0.5	2.0	-1.2	0.3	-1.4	0.2	-1.2	-0.9	-0.6	0.4	-0.7	-0.4	-0.2	0.4	-0.3	0.1	0.8
Ever had prostate specific antigen (PSA) test	3.1	3.5	5.8	-1.8	2.4	1.6	1.4	1.7	2.4	2.3	-1.9	1.6	1.9	2.0	2.1	1.5	1.9	1.3
Fractured/broken bones in last 5 years	4.4	5.6	8.8	-1.9	2.1	2.3	2.2	1.9	2.5	2.6	-2.5	2.5	2.5	2.3	3.0	2.0	2.4	2.7
Age started oral contraceptive pill	3.6	4.5	10.3	-0.3	1.9	1.9	1.7	3.2	2.4	2.4	-2.0	2.3	2.3	2.0	2.1	2.8	1.7	1.4
Diastolic blood pressure, automated reading	14.1	43.8	58.7	2.4	-5.8	-7.5	-6.4	-7.1	-7.1	-7.0	7.0	-7.7	-6.9	-6.9	-6.6	-6.6	-6.4	-6.2
Ever depressed for a whole week	0.1	0.2	1.1	-1.0	-0.4	0.4	-0.3	-0.2	-0.1	-0.4	-0.3	-0.2	-0.1	-0.1	-0.0	-0.3	-0.4	-0.5
Unable to work because of sickness or disability	1.0	1.3	6.1	0.6	-0.9	-0.7	-0.9	-0.8	-1.3	-1.0	2.5	-1.1	-0.9	-0.9	-1.2	-0.9	-1.0	-1.4
Commuting to job workplace: Cycle	2.0	2.4	6.6	1.0	0.1	2.5	1.2	1.8	1.6	1.4	-1.6	2.6	1.4	1.2	1.1	2.1	1.1	0.5
Myopia	1.7	2.5	5.0	-0.4	1.1	2.2	1.2	1.7	2.2	1.8	0.2	2.0	1.9	1.8	1.5	0.8	1.7	1.6
Vascular/heart problems diagnosed by doctor	1.5	4.2	11.1	0.8	1.4	2.8	2.0	2.0	2.2	1.9	-3.3	2.5	1.7	1.7	1.4	2.2	1.6	1.6
Cholesterol lowering medication	1.7	2.5	9.9	-0.8	-1.6	-0.2	-2.2	-1.5	-1.0	-1.6	3.1	-1.5	-1.1	-1.4	-0.7	-1.6	-1.6	-1.8
Medication: Omeprazole (e.g. Zanprol)	4.4	5.4	8.8	0.2	-2.3	-1.8	-2.4	-2.6	-1.8	-2.3	2.6	-3.0	-2.5	-2.3	-2.4	-1.9	-2.7	-2.6
Pain experienced in last month	4.2	7.0	11.5	-0.0	2.7	2.5	3.0	2.6	2.9	3.1	-1.9	2.8	2.7	2.8	2.1	3.4	2.7	2.6
Supplements: Calcium	4.7	5.2	9.0	1.1	1.6	2.8	2.3	2.9	2.6	2.5	-1.2	3.0	2.1	2.4	2.0	2.4	2.3	2.2
Basal cell carcinoma (self-reported)	0.6	0.7	2.2	1.4	0.4	1.5	0.4	0.5	0.9	1.0	0.4	1.2	0.5	0.8	0.3	0.5	1.0	0.5
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.8	0.8	-0.8	-0.1	-1.4	-0.4	-0.5	-0.7	-0.4	-0.7	-1.0	-1.0	-0.7	-0.7	-0.8	-0.8
Deep venous thrombosis (DVT) (self-reported)	6.7	8.6	12.5	2.5	-3.3	-3.1	-2.6	-2.9	-3.5	-3.3	1.3	-2.5	-3.2	-3.4	-3.4	-2.3	-3.1	-2.8
Heart disease (siblings)	3.5	4.3	5.5	1.2	-2.1	-2.2	-2.1	-2.2	-2.3	-2.0	2.4	-2.0	-2.2	-2.3	-1.7	-2.3	-1.8	-1.7
Alcohol drinker status: Previous	0.5	0.6	2.5	-1.0	-0.4	0.0	-1.3	-0.6	0.0	-0.6	1.0	-0.8	-0.2	-0.4	-0.4	-0.8	-0.5	-1.6
Pack years of smoking	0.4	0.6	2.6	1.0	-0.7	-0.6	-0.7	-0.7	-0.9	-0.8	1.6	-0.4	-0.8	-0.5	-0.5	-1.0	-0.2	-0.2
Impedance of whole body	0.9	4.4	8.4	1.9	-2.5	-1.1	-2.0	-2.3	-2.9	-2.5	2.0	-1.7	-2.1	-2.1	-2.3	0.6	-2.4	-2.1
Leg fat mass (left)	0.8	3.0	13.3	-1.9	1.1	-3.4	-0.3	-1.8	-0.1	-0.4	1.9	-2.6	-1.0	-0.9	0.0	-3.6	-0.2	-0.4
Arm predicted mass (left)	6.3	31.8	49.6	-3.4	7.0	3.9	6.2	5.8	6.8	6.9	-4.0	5.0	6.0	5.8	6.3	2.4	6.5	6.0