Best TWAS P=3.63e-12 · Best GWAS P=2.23e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | PSMA4 | 0.08 | 0.08 | lasso | 10 | 0.11 | 8.3e-35 | 4.7 | 6.5 | 7.3e-11 | -0.72 | 0.92 | 0.08 | FALSE |
| 2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | PSMA4 | 0.08 | 0.02 | blup | 40 | 0.03 | 1.1e-02 | -4.3 | -6.2 | 5.1e-10 | 0.82 | 0.02 | 0.67 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CHRNA5 | 0.15 | 0.07 | blup | 50 | 0.09 | 2.5e-04 | -6.7 | -7.0 | 3.6e-12 | 0.95 | 0.01 | 0.98 | TRUE |