[Hub]/) : Traits : Schizophrenia (2018) : ← →

chr15:84,151,637-86,040,394

Best TWAS P=1.61e-10 · Best GWAS P=9.18e-10 conditioned to 0.547

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	AC103965.1	0.24	0.14	lasso	6	0.15	2.6e-12	-6.0	6.1	1.1e-09	-0.93	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	RN7SL417P	0.07	0.06	lasso	7	0.05	1.3e-04	-5.9	-5.9	3.6e-09	0.92	0.02	0.97	FALSE
3	GTEx	Adipose Subcutaneous	RP11-182J1.14	0.11	0.11	lasso	9	0.12	8.1e-10	-5.9	-6.0	2.7e-09	0.95	0.01	0.99	FALSE
4	GTEx	Adipose Subcutaneous	CSPG4P11	0.19	0.17	lasso	5	0.20	7.9e-16	-6.0	6.0	1.4e-09	-0.93	0.01	0.99	FALSE
5	GTEx	Adipose Visceral Omentum	AC103965.1	0.12	0.13	lasso	5	0.10	1.0e-05	-6.0	6.1	1.0e-09	-0.95	0.02	0.98	FALSE
6	GTEx	Adipose Visceral Omentum	RP11-182J1.14	0.17	0.05	enet	18	0.08	6.9e-05	-5.9	-5.4	5.4e-08	0.86	0.04	0.95	FALSE
7	GTEx	Adrenal Gland	AC103965.1	0.09	0.00	enet	5	-0.01	7.7e-01	-6.1	6.1	1.3e-09	-0.99	0.02	0.82	FALSE
8	GTEx	Artery Aorta	ZNF592	0.11	0.05	enet	9	0.02	1.9e-02	-5.1	5.2	2.5e-07	-0.75	0.19	0.63	FALSE
9	GTEx	Artery Aorta	AC103965.1	0.10	0.12	lasso	3	0.10	3.9e-06	-5.9	6.0	2.1e-09	-0.96	0.01	0.99	FALSE
10	GTEx	Artery Aorta	RP11-182J1.16	0.11	0.12	lasso	3	0.11	1.6e-06	-6.0	5.9	3.8e-09	-0.95	0.01	0.99	FALSE
11	GTEx	Artery Aorta	RP11-182J1.14	0.22	0.17	enet	13	0.20	3.0e-11	-5.9	-5.5	3.2e-08	0.94	0.01	0.99	FALSE
12	GTEx	Artery Aorta	CSPG4P11	0.11	0.10	lasso	4	0.08	3.1e-05	-6.0	6.0	1.9e-09	-0.96	0.01	0.99	FALSE
13	GTEx	Artery Coronary	RP11-182J1.16	0.21	0.10	lasso	7	0.10	2.9e-04	-4.9	5.4	5.2e-08	-0.82	0.02	0.86	FALSE
14	GTEx	Artery Tibial	AC103965.1	0.27	0.26	enet	31	0.30	1.8e-23	-5.9	6.3	3.5e-10	-0.93	0.01	0.99	FALSE
15	GTEx	Artery Tibial	RP11-182J1.16	0.11	0.09	enet	14	0.08	4.1e-07	-6.0	5.7	1.3e-08	-0.89	0.01	0.99	FALSE
16	GTEx	Artery Tibial	CSPG4P11	0.16	0.24	lasso	4	0.23	3.0e-18	-5.9	6.0	1.9e-09	-0.96	0.01	0.99	FALSE
17	GTEx	Brain Caudate basal ganglia	AC103965.1	0.28	0.25	lasso	7	0.25	6.7e-08	-5.8	5.2	1.6e-07	-0.94	0.01	0.98	FALSE
18	GTEx	Brain Cerebellar Hemisphere	CSPG4P11	0.30	0.21	lasso	3	0.16	7.6e-05	-5.9	-6.0	2.7e-09	0.99	0.01	0.97	FALSE
19	GTEx	Brain Cerebellum	CSPG4P11	0.28	0.23	lasso	5	0.28	9.0e-09	-5.9	-5.9	3.7e-09	0.93	0.01	0.99	FALSE
20	GTEx	Brain Cortex	AC103965.1	0.17	0.19	lasso	3	0.16	4.3e-05	-5.8	5.9	2.8e-09	-0.96	0.02	0.95	FALSE
21	GTEx	Brain Cortex	RP11-182J1.14	0.24	0.03	enet	14	0.16	3.2e-05	-6.1	-5.5	4.2e-08	0.77	0.02	0.80	FALSE
22	GTEx	Brain Frontal Cortex BA9	AC103965.1	0.27	0.17	lasso	7	0.16	6.0e-05	-5.9	5.5	4.1e-08	-0.92	0.02	0.96	FALSE
23	GTEx	Brain Hypothalamus	AC103965.1	0.21	0.24	lasso	6	0.21	1.4e-05	-6.1	5.8	5.6e-09	-0.98	0.01	0.97	FALSE
24	GTEx	Brain Nucleus accumbens basal ganglia	AC103965.1	0.29	0.23	enet	21	0.27	6.9e-08	-5.9	6.4	1.6e-10	-0.92	0.01	0.99	TRUE
25	GTEx	Brain Putamen basal ganglia	AC103965.1	0.26	0.19	lasso	7	0.22	4.5e-06	-6.1	6.1	1.0e-09	-0.98	0.01	0.98	FALSE
26	GTEx	Breast Mammary Tissue	AC103965.1	0.13	0.11	lasso	1	0.13	2.9e-07	-5.9	6.0	2.8e-09	-0.96	0.01	0.99	FALSE
27	GTEx	Breast Mammary Tissue (Male)	AC103965.1	0.24	0.14	lasso	4	0.11	1.4e-03	-5.8	5.8	8.6e-09	-0.93	0.02	0.90	FALSE
28	GTEx	Breast Mammary Tissue (Male)	RP11-182J1.14	0.04	-0.01	enet	1	-0.01	5.9e-01	-5.9	-5.9	4.1e-09	0.99	0.02	0.41	FALSE
29	GTEx	Cells Transformed fibroblasts	NMB	0.13	0.15	lasso	6	0.15	3.6e-11	-5.2	5.1	2.7e-07	-0.74	0.43	0.57	FALSE
30	GTEx	Cells Transformed fibroblasts	AC103965.1	0.15	0.09	lasso	7	0.11	1.3e-08	-6.0	6.2	6.4e-10	-0.85	0.01	0.99	FALSE
31	GTEx	Cells Transformed fibroblasts	CSPG4P11	0.19	0.18	enet	17	0.17	9.8e-13	-6.0	5.8	8.7e-09	-0.91	0.01	0.99	FALSE
32	GTEx	Colon Sigmoid	RN7SL417P	0.17	0.06	lasso	4	0.12	6.1e-05	-5.9	-5.7	1.3e-08	0.90	0.02	0.95	FALSE
33	GTEx	Colon Sigmoid	RP11-182J1.14	0.31	0.29	lasso	9	0.30	2.7e-11	-6.1	-6.2	6.1e-10	0.99	0.01	0.99	FALSE
34	GTEx	Colon Transverse	RP11-182J1.14	0.23	0.19	enet	27	0.18	3.9e-09	-6.0	-5.7	1.3e-08	0.88	0.01	0.99	FALSE
35	GTEx	Esophagus Gastroesophageal Junction	AC103965.1	0.13	0.14	lasso	4	0.15	3.2e-06	-5.9	5.4	7.4e-08	-0.92	0.02	0.96	FALSE
36	GTEx	Esophagus Gastroesophageal Junction	RP11-182J1.14	0.16	0.16	enet	16	0.17	1.1e-06	-5.3	-5.3	1.2e-07	0.82	0.19	0.80	FALSE
37	GTEx	Esophagus Gastroesophageal Junction	CSPG4P11	0.18	0.06	lasso	2	0.06	3.5e-03	-5.9	5.4	7.5e-08	-0.92	0.02	0.93	FALSE
38	GTEx	Esophagus Mucosa	UBE2Q2P1	0.38	0.26	enet	37	0.28	3.7e-19	-5.9	-5.4	5.8e-08	0.84	0.01	0.99	FALSE
39	GTEx	Esophagus Mucosa	NMB	0.07	0.02	lasso	1	0.02	3.1e-02	-5.3	5.3	8.9e-08	-0.76	0.09	0.62	FALSE
40	GTEx	Esophagus Mucosa	AC103965.1	0.20	0.19	enet	47	0.16	8.4e-11	-5.9	5.2	2.1e-07	-0.81	0.01	0.99	FALSE
41	GTEx	Esophagus Mucosa	RP11-182J1.16	0.20	0.05	lasso	5	0.10	1.8e-07	-6.1	6.1	8.6e-10	-0.80	0.01	0.99	FALSE
42	GTEx	Esophagus Muscularis	AC103965.1	0.18	0.14	enet	16	0.14	7.6e-09	-5.9	6.1	1.2e-09	-0.96	0.01	0.99	FALSE
43	GTEx	Esophagus Muscularis	RP11-182J1.16	0.12	0.10	lasso	8	0.11	4.5e-07	-6.0	5.5	3.4e-08	-0.90	0.02	0.98	FALSE
44	GTEx	Esophagus Muscularis	RP11-182J1.14	0.12	0.09	enet	16	0.09	4.6e-06	-5.9	-5.5	2.8e-08	0.94	0.02	0.98	FALSE
45	GTEx	Esophagus Muscularis	CSPG4P11	0.12	0.16	lasso	5	0.18	4.0e-11	-6.0	6.0	2.0e-09	-0.95	0.01	0.99	FALSE
46	GTEx	Heart Atrial Appendage	RP11-182J1.14	0.06	0.05	lasso	3	0.05	3.6e-03	-6.1	-6.1	9.3e-10	1.00	0.02	0.92	FALSE
47	GTEx	Heart Atrial Appendage	CSPG4P11	0.12	0.08	lasso	5	0.10	4.3e-05	-5.9	5.5	3.8e-08	-0.91	0.03	0.97	FALSE
48	GTEx	Heart Left Ventricle	AC103965.1	0.16	0.13	enet	14	0.12	7.0e-07	-5.9	5.8	6.1e-09	-0.92	0.01	0.99	FALSE
49	GTEx	Heart Left Ventricle	CSPG4P11	0.11	0.02	lasso	5	0.00	2.2e-01	-6.0	6.0	2.6e-09	-0.94	0.02	0.91	FALSE
50	GTEx	Lung	AC103965.1	0.20	0.14	lasso	4	0.16	1.8e-12	-5.9	5.6	2.5e-08	-0.90	0.01	0.99	FALSE
51	GTEx	Muscle Skeletal	CSPG4P11	0.14	0.07	lasso	5	0.08	1.4e-08	-3.6	5.2	1.9e-07	-0.84	0.02	0.98	FALSE
52	GTEx	Nerve Tibial	AC103965.1	0.20	0.22	enet	17	0.27	5.1e-19	-5.9	5.9	2.9e-09	-0.96	0.01	0.99	FALSE
53	GTEx	Nerve Tibial	RP11-182J1.16	0.27	0.20	enet	22	0.26	1.5e-18	-6.0	5.4	8.1e-08	-0.89	0.01	0.99	FALSE
54	GTEx	Nerve Tibial	CSPG4P11	0.23	0.23	lasso	9	0.27	3.0e-19	-6.0	5.6	2.7e-08	-0.95	0.01	0.99	FALSE
55	GTEx	Ovary	CSPG4P11	0.21	0.17	lasso	4	0.18	3.1e-05	-5.3	5.5	3.0e-08	-0.87	0.03	0.92	FALSE
56	GTEx	Pancreas	NMB	0.17	0.18	lasso	3	0.14	2.3e-06	-5.4	5.4	5.3e-08	-0.76	0.21	0.78	FALSE
57	GTEx	Pancreas	AC103965.1	0.29	0.23	lasso	9	0.18	2.8e-08	-6.0	6.0	2.3e-09	-0.94	0.01	0.99	FALSE
58	GTEx	Pituitary	AC103965.1	0.30	0.16	enet	10	0.24	8.4e-07	-5.3	5.8	4.9e-09	-0.89	0.02	0.96	FALSE
59	GTEx	Prostate	RP11-182J1.16	0.24	0.06	enet	27	0.08	6.2e-03	-3.5	5.3	1.2e-07	-0.75	0.03	0.65	FALSE
60	GTEx	Prostate	RP11-182J1.14	0.25	0.09	enet	25	0.09	2.9e-03	-5.9	-5.3	9.4e-08	0.77	0.04	0.79	FALSE
61	GTEx	Skin Not Sun Exposed Suprapubic	AC103965.1	0.23	0.15	lasso	8	0.19	1.9e-10	-6.0	5.5	3.5e-08	-0.80	0.02	0.98	FALSE
62	GTEx	Skin Sun Exposed Lower leg	AC103965.1	0.33	0.17	enet	24	0.23	4.8e-19	-5.9	5.1	3.1e-07	-0.80	0.01	0.99	FALSE
63	GTEx	Spleen	NMB	0.14	0.17	lasso	4	0.15	1.1e-04	-5.1	5.3	1.3e-07	-0.76	0.10	0.70	FALSE
64	GTEx	Stomach	AC103965.1	0.14	0.11	lasso	3	0.10	1.1e-05	-5.8	5.4	5.3e-08	-0.90	0.03	0.96	FALSE
65	GTEx	Testis	NMB	0.47	0.57	enet	37	0.57	1.4e-30	-5.1	-5.2	2.1e-07	0.74	0.32	0.68	FALSE
66	GTEx	Testis	AC103965.1	0.07	0.07	lasso	2	0.06	1.6e-03	-5.9	5.9	3.0e-09	-0.96	0.02	0.97	FALSE
67	GTEx	Testis	RN7SL417P	0.09	0.08	lasso	3	0.08	3.1e-04	-5.9	-5.5	5.0e-08	0.89	0.02	0.93	FALSE
68	GTEx	Testis	RP11-182J1.14	0.10	0.19	lasso	1	0.17	6.7e-08	-5.9	-6.0	2.8e-09	0.96	0.01	0.99	FALSE
69	GTEx	Thyroid	ZSCAN2	0.06	0.03	lasso	2	0.03	2.9e-03	-5.4	-5.1	3.1e-07	0.74	0.08	0.72	FALSE
70	GTEx	Thyroid	AC103965.1	0.30	0.25	lasso	7	0.25	1.8e-19	-6.0	6.0	2.7e-09	-0.93	0.01	0.99	FALSE
71	METSIM	Adipose	NMB	0.08	0.10	lasso	9	0.10	6.8e-15	-5.2	5.3	1.2e-07	-0.75	0.46	0.54	FALSE
72	YFS	Blood	NMB	0.05	0.09	lasso	4	0.09	1.9e-26	-5.4	5.4	5.3e-08	-0.75	0.23	0.77	FALSE
73	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC388152	0.13	0.10	enet	2	0.11	3.3e-22	-5.9	5.3	1.0e-07	-0.89	0.00	1.00	FALSE
74	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC388152	0.07	0.04	blup	4	0.05	1.3e-03	-5.6	5.2	1.8e-07	-0.88	0.00	0.83	FALSE
75	The Cancer Genome Atlas	Esophageal Carcinoma	LOC388152	0.10	0.08	enet	2	0.08	1.8e-03	-5.6	5.7	1.1e-08	-0.96	0.00	0.73	FALSE
76	The Cancer Genome Atlas	Glioblastoma Multiforme	LOC388152	0.12	0.08	lasso	3	0.08	1.9e-03	-6.0	6.0	1.7e-09	-0.92	0.00	0.70	FALSE
77	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LOC388152	0.03	0.02	enet	4	0.01	8.8e-03	-6.0	5.5	3.6e-08	-0.83	0.00	0.76	FALSE
78	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LOC388152	0.05	0.05	blup	4	0.05	3.9e-06	-5.9	5.7	1.5e-08	-0.93	0.00	1.00	FALSE
79	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LOC388152	0.19	0.17	blup	4	0.18	1.8e-10	-5.6	5.3	1.0e-07	-0.90	0.00	1.00	FALSE
80	The Cancer Genome Atlas	Brain Lower Grade Glioma	LOC388152	0.11	0.08	enet	3	0.09	2.1e-10	-6.0	5.3	1.3e-07	-0.86	0.00	1.00	FALSE
81	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	NMB	0.06	0.04	enet	9	0.02	2.7e-02	-5.3	5.1	2.9e-07	-0.71	0.01	0.75	FALSE
82	The Cancer Genome Atlas	Lung Adenocarcinoma	LOC388152	0.12	0.10	blup	4	0.10	4.9e-12	-5.9	5.6	2.1e-08	-0.92	0.00	1.00	FALSE
83	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LOC388152	0.02	0.03	lasso	1	0.02	1.2e-03	-5.6	5.6	2.1e-08	-0.96	0.00	0.92	FALSE
84	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UBE2Q2P1	0.03	0.03	lasso	3	0.02	9.2e-04	-6.0	-6.0	2.1e-09	0.94	0.00	0.94	FALSE
85	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LOC388152	0.04	0.05	enet	2	0.05	4.2e-04	-5.9	5.8	7.3e-09	-0.96	0.00	0.89	FALSE
86	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LOC388152	0.08	0.11	lasso	3	0.11	2.4e-05	-6.0	6.0	1.7e-09	-0.92	0.00	0.98	FALSE
87	The Cancer Genome Atlas	Prostate Adenocarcinoma	NMB	0.17	0.30	enet	12	0.29	5.3e-31	-5.4	5.6	2.3e-08	-0.74	0.01	0.99	FALSE
88	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LOC388152	0.18	0.14	blup	4	0.13	2.1e-05	-6.0	5.6	2.3e-08	-0.92	0.00	0.99	FALSE
89	The Cancer Genome Atlas	Thyroid Carcinoma	LOC388152	0.29	0.26	enet	3	0.27	2.1e-26	-5.9	5.8	6.2e-09	-0.94	0.00	1.00	FALSE
90	The Cancer Genome Atlas	Thyroid Carcinoma	NMB	0.11	0.11	lasso	3	0.09	1.8e-09	-5.3	-5.4	7.6e-08	0.76	0.01	0.99	FALSE