TWAS hub - TOM1L2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1930	0.0480	0.0e+00	0.239	0.206	0.225	0.244	0.238	9.8e-29	1.6e-24	6.0e-27	2.5e-29	1.1e-28
2	GTEx	Adipose Subcutaneous	0.0390	0.0190	1.2e-03	0.036	NA	0.030	NA	0.037	5.6e-04	NA	1.7e-03	NA	5.3e-04
3	GTEx	Adipose Visceral Omentum	0.1540	0.0550	6.4e-06	0.129	NA	0.087	NA	0.107	3.3e-07	NA	2.9e-05	NA	3.6e-06
4	GTEx	Artery Tibial	0.0562	0.0257	1.5e-04	0.021	NA	0.041	NA	0.032	8.1e-03	NA	3.8e-04	NA	1.4e-03
5	GTEx	Brain Cerebellum	0.0990	0.0570	6.9e-03	0.059	NA	0.022	NA	0.024	8.1e-03	NA	7.5e-02	NA	6.6e-02
6	GTEx	Cells Transformed fibroblasts	0.0500	0.0250	3.7e-03	-0.001	NA	0.001	NA	-0.002	3.7e-01	NA	2.8e-01	NA	4.8e-01
7	GTEx	Esophagus Muscularis	0.0650	0.0280	3.5e-04	0.070	NA	0.052	NA	0.044	4.8e-05	NA	4.3e-04	NA	1.1e-03
8	GTEx	Heart Atrial Appendage	0.1220	0.0610	4.6e-03	0.037	NA	0.040	NA	0.018	8.6e-03	NA	7.0e-03	NA	5.1e-02
9	GTEx	Lung	0.0688	0.0351	3.6e-04	0.025	NA	0.031	NA	0.033	5.0e-03	NA	2.0e-03	NA	1.4e-03
10	GTEx	Muscle Skeletal	0.0759	0.0248	4.3e-09	0.110	NA	0.099	NA	0.100	6.7e-11	NA	5.8e-10	NA	5.3e-10
11	GTEx	Nerve Tibial	0.1051	0.0473	9.5e-06	0.042	NA	0.100	NA	0.079	6.0e-04	NA	1.5e-07	NA	2.9e-06
12	GTEx	Ovary	0.2780	0.1190	3.9e-04	0.013	NA	0.007	NA	0.044	1.5e-01	NA	2.1e-01	NA	3.1e-02
13	GTEx	Pituitary	0.4310	0.1150	1.3e-07	0.199	NA	0.107	NA	0.095	9.8e-06	NA	1.3e-03	NA	2.3e-03
14	GTEx	Stomach	0.1230	0.0560	4.9e-03	-0.005	NA	0.000	NA	-0.004	7.2e-01	NA	3.2e-01	NA	5.7e-01
15	ROSMAP	Brain Pre-frontal Cortex	0.1519	0.0488	4.8e-12	0.108	0.098	0.077	0.096	0.093	9.6e-14	1.4e-12	3.6e-10	2.4e-12	5.2e-12
16	TCGA	Breast Invasive Carcinoma	0.0137	0.0115	1.8e-03	0.009	0.011	0.008	NA	0.009	4.3e-03	1.8e-03	6.3e-03	NA	4.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	15	16
Waist Hip Ratio (WHR)	13.3	60.0	98.6	-7.3	-8.4	-8.4	-9.0	-7.9	-9.9	-7.4	-4.7	-8.5	-8.3	-6.8	-5.8	-8.2	-9.0	-8.6
Coronary Artery Disease (CAD)	11.7	14.0	21.8	-3.5	-4.2	-3.6	-4.5	-4.4	-3.3	-3.6	-0.4	-4.6	-4.3	-3.3	-3.1	-4.7	-4.0	-4.3
Heart attack	9.6	12.3	20.4	-3.9	-4.0	-4.0	-3.3	-4.2	-3.5	-3.5	-0.5	-3.7	-4.0	-3.1	-2.1	-4.0	-4.5	-4.0
Pulse rate	9.6	16.2	21.1	-4.4	-4.6	-4.5	-3.9	-4.5	-4.3	-4.6	-2.2	-3.8	-4.5	-3.2	-3.9	-4.3	-4.4	-4.5
Schizophrenia (2014)	9.3	20.6	30.9	-4.8	-5.3	-5.3	-4.7	-5.1	-3.8	-5.4	-0.1	-4.6	-5.2	-4.2	-4.7	-4.5	-4.2	-5.6
Heart attack/myocardial infarction (self-reported)	9.1	11.7	20.4	-3.9	-3.9	-3.9	-3.2	-4.0	-3.2	-3.5	-0.6	-3.6	-3.9	-3.1	-1.9	-3.9	-4.5	-3.9
Schizophrenia (2018)	8.5	17.6	27.1	-4.3	-4.9	-4.8	-4.4	-4.6	-3.4	-5.1	-1.0	-4.2	-4.8	-4.3	-4.0	-4.1	-4.1	-5.2
Alzheimer’s Disease (in mother)	8.2	9.6	16.0	3.0	3.4	3.1	3.0	3.6	3.1	3.7	0.8	3.8	3.0	3.3	4.0	3.3	2.4	3.2
Health satisfaction	8.2	10.6	15.4	-3.4	-3.2	-3.5	-3.4	-3.8	-3.8	-3.4	1.6	-3.2	-3.6	-3.9	-3.3	-3.3	-3.1	-3.4
Blood White Count	7.5	55.8	86.5	-7.6	-8.1	-8.2	-8.2	-9.3	-7.2	-6.9	-0.9	-8.7	-8.3	-8.6	-5.8	-8.3	-7.5	-8.4
Number of self-reported non-cancer illnesses	7.5	12.9	20.3	-3.8	-4.0	-3.9	-4.0	-4.1	-3.4	-4.5	2.0	-3.5	-3.8	-2.4	-4.0	-4.3	-3.1	-4.1
Pain experienced in last month	7.2	12.1	19.5	3.5	3.7	3.7	4.1	3.2	3.1	4.0	-1.4	3.7	3.4	3.8	4.0	4.4	3.1	3.7
Allergy or Eczema	7.1	18.6	31.1	-4.5	-4.5	-4.8	-5.0	-5.6	-3.4	-4.3	-0.5	-4.6	-4.9	-5.3	-3.9	-4.8	-3.7	-4.8
Pulse wave reflection index	7.1	8.8	15.8	3.5	3.5	3.4	2.4	2.9	3.1	4.0	1.1	2.4	3.3	2.3	3.0	2.9	3.4	3.6
Schizophrenia vs Biploar Disorder	6.8	8.9	14.6	-2.8	-3.4	-3.1	-3.8	-3.1	-3.2	-3.3	-1.1	-3.0	-3.1	-3.7	-2.8	-2.6	-2.8	-3.5
Overall health rating	6.7	14.4	21.3	-4.0	-4.3	-4.1	-3.7	-4.2	-4.1	-4.5	0.5	-3.2	-4.1	-4.4	-3.8	-4.6	-3.3	-4.0
Alzheimer’s Disease (including proxy)	6.6	9.6	15.9	3.3	3.5	3.2	2.8	3.8	2.8	4.0	0.8	3.7	3.3	2.8	3.8	3.0	2.6	3.4
Sensitivity / hurt feelings	6.5	11.1	19.5	-3.6	-3.2	-3.6	-3.0	-3.6	-3.1	-3.4	3.2	-3.4	-3.6	-2.6	-4.3	-4.4	-2.7	-3.3
Reaction Time	6.4	12.1	24.5	-5.0	-4.2	-4.4	-3.0	-4.6	-2.0	-3.3	0.7	-2.9	-4.8	-1.9	-2.2	-3.3	-4.4	-4.1
HbA1C	6.2	6.9	17.1	-2.1	-3.0	-1.8	-4.1	-2.6	-2.5	-2.2	-1.4	-3.2	-3.1	-3.2	-2.1	-2.6	-2.4	-3.0
Time employed in main current job	6.1	7.0	12.5	-3.1	-3.0	-3.0	-2.4	-3.5	-2.2	-2.7	0.1	-2.8	-3.2	-2.0	-1.9	-2.6	-3.5	-3.0
Pulse rate, automated reading	6.1	19.8	34.1	-4.8	-5.2	-5.1	-3.6	-5.5	-5.8	-4.3	-1.2	-3.9	-5.3	-4.2	-4.0	-4.6	-4.5	-5.0
Medication: Atenolol	5.9	7.4	14.0	-2.9	-3.0	-3.2	-3.1	-3.0	-2.2	-2.9	-0.0	-2.7	-3.2	-1.3	-2.0	-3.0	-3.7	-3.4
Verbal and Numeric Reasoning (VNR)	5.8	13.9	24.2	4.4	4.2	4.1	2.8	4.9	4.3	3.5	1.8	4.5	4.3	3.1	2.0	4.3	3.8	4.1
Mean time to correctly identify matches	5.8	11.1	21.6	-4.7	-4.2	-4.2	-3.0	-4.3	-1.9	-3.2	1.2	-2.3	-4.6	-1.8	-2.1	-2.8	-4.5	-4.0
Prostate Cancer	5.7	7.9	11.8	-3.2	-2.9	-3.2	-2.3	-3.0	-2.8	-3.0	1.0	-3.4	-3.3	-2.2	-3.2	-3.2	-2.8	-3.2
Impedance of leg (left)	5.7	27.8	41.3	-6.1	-6.0	-6.2	-4.5	-6.4	-5.6	-6.0	-1.8	-6.3	-6.4	-2.8	-3.4	-5.2	-6.0	-6.1
Illnesses of siblings: Diabetes	5.7	7.0	11.2	-3.0	-3.1	-3.0	-2.6	-3.3	-2.5	-2.8	-0.4	-2.8	-3.0	-3.0	-1.5	-2.6	-2.7	-3.1
Medication: Ramipril	5.6	7.3	12.9	-2.2	-2.7	-2.5	-3.4	-2.8	-1.4	-3.0	2.0	-3.1	-2.6	-2.9	-3.5	-3.6	-2.1	-2.9
Hayfever, allergic rhinitis or eczema	5.5	12.0	21.8	-3.7	-3.4	-3.8	-3.9	-4.7	-2.6	-3.2	-1.2	-3.8	-3.9	-4.6	-2.9	-3.7	-3.1	-3.7
Ever had bowel cancer screening	5.3	6.2	11.2	2.7	2.6	2.7	3.4	2.8	2.0	2.7	1.2	3.0	2.8	1.8	2.5	3.0	2.0	2.8
Medication: Atorvastatin	5.2	6.5	10.7	-2.5	-2.5	-2.6	-3.3	-2.9	-2.3	-2.5	1.6	-2.5	-2.8	-2.5	-2.9	-3.2	-2.2	-2.7
Fluid intelligence score	5.0	10.3	20.0	3.8	3.4	3.5	2.5	4.4	4.5	2.6	2.2	4.0	3.6	2.5	1.3	3.6	3.2	3.2
Osteoporosis (self-reported)	5.0	6.2	11.4	2.6	2.9	2.7	2.6	3.4	2.3	2.6	-2.0	2.7	3.0	0.9	2.7	2.4	2.0	2.9
Frequency of unenthusiasm / disinterest in last 2 weeks	4.9	6.5	12.0	-1.9	-2.5	-2.5	-3.1	-2.2	-2.6	-3.1	2.4	-2.6	-2.4	-2.4	-3.2	-3.5	-2.0	-2.6
Impedance of leg (right)	4.8	23.1	33.8	-5.5	-5.4	-5.6	-4.1	-5.8	-5.4	-5.3	-2.0	-5.7	-5.8	-2.6	-2.9	-4.9	-5.5	-5.5
Intelligence (Savage-Jansen 2018)	4.6	14.2	23.8	4.3	4.3	4.2	3.1	4.9	4.5	4.1	1.6	4.6	4.4	1.6	2.3	4.4	4.0	4.1
Diabetes (self-reported)	4.6	7.0	11.9	-3.2	-3.0	-3.3	-2.2	-3.4	-3.4	-2.6	0.7	-2.8	-3.2	-1.6	-1.9	-2.7	-2.8	-2.9
Heart disease (siblings)	4.6	5.6	8.9	-2.4	-2.6	-2.6	-2.7	-2.2	-1.9	-2.5	0.0	-2.9	-2.5	-2.8	-1.8	-2.4	-3.0	-2.7
Breast Cancer	4.5	10.7	24.5	3.8	3.8	3.9	2.4	2.9	2.3	4.2	-1.2	2.2	3.6	2.6	5.0	3.8	3.2	3.9
Systolic Blood Pressure	4.5	22.7	46.5	-4.7	-5.2	-5.1	-6.2	-4.9	-3.6	-5.6	3.6	-4.5	-5.3	-1.9	-6.8	-4.7	-4.1	-5.6
Bipolar Disorder or Schizophrenia	4.3	10.4	17.0	-3.3	-3.8	-3.8	-3.1	-3.8	-2.1	-4.0	-0.4	-3.4	-3.8	-3.2	-3.0	-3.2	-3.1	-4.1
Lung FEV1/FVC ratio	4.3	21.7	42.6	-4.3	-4.8	-5.1	-5.5	-4.6	-4.7	-4.1	-1.5	-6.2	-5.1	-6.5	-3.1	-5.0	-4.2	-5.2
Frequency of tenseness / restlessness in last 2 weeks	4.2	6.6	12.5	-2.3	-2.5	-2.7	-2.0	-2.2	-1.9	-3.1	3.4	-2.0	-2.5	-2.2	-3.3	-3.5	-2.5	-2.8
Headache pain in last month	4.2	7.3	14.8	-2.6	-3.0	-2.9	-2.6	-2.9	-2.7	-3.1	0.9	-2.4	-2.8	-2.9	-3.8	-3.2	-2.0	-2.9
Average weekly spirits intake	4.1	5.1	9.5	-2.5	-2.6	-2.5	-2.0	-2.6	-2.9	-2.5	-0.4	-2.6	-2.7	-0.6	-1.2	-3.1	-2.6	-2.4
Type 2 Diabetes (T2D) (2018)	4.0	7.5	11.7	-3.3	-3.3	-3.4	-2.0	-3.4	-3.3	-2.8	0.0	-3.3	-3.2	-1.4	-2.0	-3.2	-2.6	-3.0
Lung FVC	4.0	20.3	33.1	5.5	5.4	5.6	4.2	4.7	3.2	5.0	2.7	4.8	5.5	3.2	2.7	4.4	5.8	5.5
Medication: Bendroflumethiazide	3.9	5.9	12.8	-2.6	-2.7	-2.5	-2.3	-2.8	-2.1	-2.8	2.8	-1.7	-2.5	-1.4	-3.6	-2.2	-2.1	-2.7
Blood Eosinophil Count	3.7	28.8	46.8	-5.4	-5.4	-5.6	-6.3	-6.0	-4.1	-5.7	3.5	-5.1	-5.5	-6.1	-6.3	-6.8	-4.8	-5.7
Maternal smoking around birth	3.7	5.3	10.3	2.4	2.6	2.7	2.2	2.7	1.4	2.8	0.3	3.2	2.8	2.3	2.3	1.9	1.6	3.0
Diabetes diagnosed by doctor	3.7	6.1	11.3	-2.9	-2.7	-3.0	-2.2	-3.4	-2.9	-2.3	-0.1	-3.0	-3.0	-1.8	-1.3	-2.7	-2.6	-2.6
Nervous feelings	3.6	6.8	14.1	-2.4	-2.3	-2.6	-2.5	-2.5	-3.3	-2.5	1.4	-3.3	-2.4	-3.1	-2.0	-3.8	-2.9	-2.4
Smoking status: Previous	3.5	5.2	8.3	2.4	2.4	2.7	2.4	2.6	2.4	2.7	0.4	2.7	2.5	1.9	1.9	2.1	2.2	2.9
Vascular/heart problems diagnosed by doctor	3.5	9.6	13.2	3.4	3.4	3.4	3.6	3.2	2.2	3.5	-2.4	2.7	3.4	1.8	3.6	3.4	3.6	3.6
Hair/balding pattern: Pattern 2	3.3	4.2	6.4	-2.5	-2.4	-2.4	-1.5	-2.1	-2.3	-2.3	1.9	-1.7	-2.4	-1.0	-2.3	-2.5	-1.7	-2.0
Hayfever/allergic rhinitis (self-reported)	3.3	4.3	9.5	-1.9	-1.7	-1.9	-3.0	-2.8	-1.5	-2.2	0.0	-2.7	-1.9	-3.1	-1.6	-2.5	-1.5	-2.0
Birth weight of first child	3.3	6.0	17.9	2.7	2.1	2.4	3.6	2.5	2.5	2.2	1.6	1.5	2.8	0.6	2.2	4.2	2.7	2.5
Myopia	3.3	4.8	8.2	-2.5	-2.9	-2.7	-1.9	-2.4	-1.5	-2.5	0.0	-2.1	-2.6	-2.1	-2.6	-2.3	-1.9	-2.6
Systolic blood pressure, automated reading	3.2	9.3	16.3	-3.2	-3.5	-3.4	-4.0	-3.3	-2.2	-3.7	1.7	-2.8	-3.6	-0.7	-3.7	-2.6	-3.1	-3.8
Supplements: Glucosamine	3.2	4.1	7.9	2.4	2.1	2.4	1.6	2.7	0.4	1.4	2.1	2.6	2.5	2.1	0.4	1.8	2.8	2.2
Body Mass Index (BMI) (2010)	3.1	4.2	7.3	2.4	2.5	2.5	2.0	2.7	1.9	1.9	-0.1	2.4	2.5	0.6	1.3	2.0	2.6	2.3
Hip circumference	3.1	13.1	33.4	3.3	3.7	4.1	3.2	4.1	5.8	3.0	-0.5	4.7	4.1	3.4	3.4	3.4	3.2	3.9
Happiness	3.1	3.7	6.1	-2.2	-2.1	-2.2	-2.2	-2.2	-0.7	-1.9	0.1	-1.8	-2.2	-2.5	-1.9	-2.1	-2.2	-2.2
Length of working week for main job	3.1	3.5	8.8	-2.2	-2.2	-2.1	-0.8	-1.6	-0.7	-3.0	-0.8	-2.0	-1.9	-0.9	-2.4	-2.0	-1.9	-2.5
Tense / ‘highly strung’	3.1	5.1	16.2	-2.0	-2.0	-2.0	-2.2	-1.5	-1.4	-2.4	4.0	-1.9	-1.8	-1.3	-3.2	-3.4	-2.1	-2.1
Triglycerides	3.0	4.9	10.2	-2.4	-2.4	-2.6	-1.9	-2.4	-2.9	-2.0	-1.1	-2.4	-2.5	-1.8	-1.4	-1.7	-3.2	-2.6
Angina	3.0	3.9	6.7	-2.2	-2.0	-2.2	-1.4	-2.4	-1.9	-1.7	-1.2	-2.1	-2.4	-2.2	-0.6	-2.6	-2.5	-2.2
Alcohol usually taken with meals	3.0	4.8	7.7	-2.7	-2.5	-2.6	-1.9	-2.6	-2.7	-2.8	-1.1	-2.0	-2.8	-0.3	-1.3	-2.0	-2.3	-2.6
Mother’s age at death	3.0	3.8	7.7	2.3	1.8	2.0	2.5	2.1	1.7	1.2	-1.5	2.8	2.1	1.3	1.8	2.5	2.2	1.8
Fed-up feelings	2.9	5.3	13.5	-2.3	-1.8	-2.6	-2.6	-2.0	-2.5	-2.4	0.6	-2.3	-2.4	-2.8	-2.6	-3.7	-1.8	-2.3
Angina (self-reported)	2.9	3.7	6.6	-2.1	-2.0	-2.1	-1.4	-2.3	-1.7	-1.7	-1.3	-2.0	-2.3	-2.0	-0.5	-2.6	-2.6	-2.2
Allergy	2.8	6.4	13.2	2.7	2.5	2.6	2.9	3.6	2.3	2.4	0.3	2.7	2.8	3.0	2.3	3.1	2.2	2.5
Mouth/teeth dental problems: Dentures	2.8	4.7	9.5	-2.8	-2.5	-2.5	-1.7	-2.1	-1.5	-2.4	-0.8	-2.1	-2.5	-1.0	-2.0	-3.1	-2.8	-2.5
Number of treatments/medications taken	2.7	4.8	9.9	-2.3	-2.3	-2.3	-2.6	-2.3	-2.2	-2.5	1.5	-1.9	-2.3	-2.0	-2.0	-3.1	-1.9	-2.4
Pain all over the body in last month	2.7	2.9	6.6	-1.9	-2.2	-2.0	-1.7	-1.2	-1.3	-2.6	0.0	-1.8	-1.7	0.2	-1.8	-1.5	-1.8	-2.3
Neuroticism score	2.7	5.7	13.5	-2.0	-1.9	-2.2	-2.6	-1.6	-1.7	-2.6	3.7	-2.2	-2.0	-2.2	-3.4	-3.6	-1.8	-2.2
Number of live births	2.7	3.8	8.1	2.1	1.8	2.0	1.2	2.0	2.8	2.2	-1.8	1.1	2.0	1.6	2.9	2.5	1.5	1.9
Pack years of smoking	2.7	3.9	7.7	-2.7	-2.2	-2.4	-1.6	-2.8	-1.1	-2.2	-0.5	-0.9	-2.6	-0.6	-1.8	-2.6	-2.4	-2.2
Bipolar Disorder (2011)	2.6	2.5	4.4	-1.9	-1.6	-1.9	-1.4	-2.1	-1.8	-1.2	0.4	-1.9	-1.9	-1.4	-1.0	-1.9	-1.8	-1.6
Diabetes (mother)	2.6	3.3	7.8	-1.6	-1.6	-1.9	-1.4	-2.1	-1.4	-1.7	-1.9	-2.6	-1.8	-2.8	-0.5	-2.2	-1.7	-1.9
Townsend deprivation index at recruitment	2.6	3.6	6.2	2.1	2.2	2.4	0.8	2.1	1.4	2.5	-0.2	1.8	2.4	1.4	2.4	1.3	2.3	2.4
Forced vital capacity (FVC)	2.6	10.0	17.3	4.0	3.9	4.0	1.8	3.5	2.4	4.2	-1.4	3.1	3.9	1.4	2.8	3.2	3.7	3.9
Age started oral contraceptive pill	2.6	3.2	6.0	-2.5	-2.3	-2.3	-1.6	-1.9	-0.3	-2.1	-1.6	-1.1	-2.3	-1.2	-0.6	-1.5	-2.4	-2.3
Alcohol drinker status: Previous	2.6	2.9	4.6	2.1	2.0	2.0	1.4	2.0	0.3	1.6	-1.5	1.9	2.1	1.2	1.7	1.7	1.9	2.1
Worry (Nagel 2018)	2.5	5.3	17.2	-1.6	-1.7	-1.9	-2.3	-1.5	-2.0	-2.6	4.1	-2.5	-1.6	-2.2	-2.8	-3.3	-1.8	-2.1
Diverticular disease/diverticulitis (self-reported)	2.5	3.0	5.8	-1.8	-1.8	-1.7	-2.0	-2.2	-2.4	-1.5	0.2	-1.7	-1.8	-2.1	-1.2	-1.9	-1.6	-1.6
Comparative body size at age 10	2.5	6.9	11.6	3.1	3.3	3.3	2.3	3.1	3.4	2.5	0.3	2.5	3.3	1.9	1.9	2.8	1.8	3.1
Knee pain experienced in last month	2.5	3.9	7.9	-2.3	-2.4	-2.2	-1.9	-1.7	-1.5	-2.8	1.0	-1.3	-2.2	-1.8	-2.8	-2.0	-1.3	-2.5
Hypertension (Self-reported)	2.5	7.0	14.0	-2.7	-2.8	-2.8	-3.4	-2.4	-1.8	-3.3	2.4	-1.9	-2.8	-0.8	-3.7	-2.7	-3.0	-3.1
Cardiovascular Disease	2.4	8.0	18.7	-2.2	-2.6	-2.5	-4.1	-2.3	-2.2	-3.1	3.7	-2.2	-2.4	-2.7	-4.3	-3.1	-2.0	-2.9
Suffer from ‘nerves’	2.4	3.7	5.9	-1.5	-1.8	-1.9	-1.6	-1.7	-2.4	-2.3	1.8	-1.7	-1.7	-2.2	-2.4	-2.3	-1.9	-2.2
High blood pressure	2.3	6.4	13.2	-2.6	-2.6	-2.6	-3.2	-2.3	-1.7	-3.0	2.8	-1.8	-2.6	-0.8	-3.6	-2.6	-2.6	-2.9
Exposure to tobacco smoke outside home	2.3	3.0	7.3	-1.8	-1.4	-1.7	-1.8	-1.4	-2.3	-2.0	0.7	-1.7	-1.7	-1.7	-2.3	-2.7	-1.4	-1.6
Alcohol intake frequency.	2.3	5.3	12.9	-2.5	-2.3	-2.6	-1.7	-2.1	-2.9	-1.9	-3.6	-3.1	-2.4	-1.3	0.8	-2.2	-2.8	-2.3
Mouth/teeth dental problems: Mouth ulcers	2.3	3.7	6.0	1.7	2.1	2.1	2.4	2.4	0.9	2.2	-0.2	2.3	2.1	2.0	1.9	2.3	1.2	2.3
Neuroticism (Nagel 2018)	2.2	5.1	24.3	-1.4	-1.4	-1.8	-1.9	-1.1	-2.0	-2.3	4.9	-2.2	-1.4	-1.8	-3.4	-3.4	-0.9	-1.6
Neuroticism	2.2	5.3	13.8	-1.4	-1.6	-1.9	-2.6	-1.1	-1.9	-2.5	3.7	-2.1	-1.6	-2.9	-3.7	-3.1	-1.1	-2.0
Depression (self-reported)	2.2	2.6	7.0	1.9	1.6	1.8	1.4	1.8	0.9	0.9	2.4	1.9	2.0	0.8	-0.0	1.5	2.6	1.7
Medication for cholesterol	2.2	3.3	9.5	1.7	1.8	2.0	3.1	1.7	2.2	1.4	-0.3	1.2	2.0	1.9	1.9	2.2	1.3	2.0
Back pain experienced in last month	2.2	3.1	8.4	-1.3	-1.6	-1.6	-1.2	-1.3	-1.9	-1.9	2.9	-1.5	-1.4	-2.1	-2.9	-2.0	-1.0	-1.6
Medication: Blood pressure	2.2	4.1	11.0	-1.9	-2.1	-2.1	-3.3	-1.7	-1.3	-2.2	0.9	-1.3	-2.0	-1.8	-3.1	-2.2	-2.1	-2.3
Blood Red Count	2.1	20.4	35.9	-5.3	-4.9	-5.0	-5.1	-5.3	-4.1	-4.5	-2.9	-5.2	-5.2	-1.8	-3.2	-4.6	-6.0	-5.1
Pack years adult smoking proportion	2.1	3.2	7.3	-2.5	-1.9	-2.1	-1.3	-2.7	-1.2	-2.0	-0.2	-0.8	-2.4	-0.6	-1.6	-2.4	-2.1	-1.9
Medication: Levothyroxine sodium	2.1	3.5	9.3	-1.4	-1.8	-1.8	-3.0	-2.3	-1.7	-2.3	1.3	-1.8	-1.8	-1.4	-1.8	-2.6	-0.8	-2.0
Falls in the last year	2.1	2.8	6.0	1.8	2.0	1.9	1.6	2.5	2.2	1.7	-0.1	1.5	2.0	1.1	1.6	1.2	1.6	2.0
Exposure to tobacco smoke at home	2.1	2.4	4.8	-2.2	-1.9	-2.1	-1.2	-1.4	-0.2	-2.2	-1.1	-1.2	-2.0	-0.1	-1.4	-1.3	-1.6	-2.1
Medication for cholesterol, blood pressure or diabetes	2.1	3.5	6.9	1.5	1.8	1.6	2.3	1.9	1.8	1.9	-2.6	2.0	1.7	1.3	1.8	2.6	1.8	1.9
Supplements: Vitamin C	2.1	2.5	7.5	-1.6	-1.6	-1.4	-2.7	-1.6	-1.4	-2.0	-1.2	-1.1	-1.4	-0.7	-1.6	-2.4	-1.1	-1.6
Ovarian Cancer	2.0	2.6	5.3	-2.3	-1.8	-2.2	-1.1	-1.7	-1.0	-2.2	-1.1	-1.3	-2.1	-0.3	-0.6	-1.5	-1.9	-2.0
Medication: Omeprazole	2.0	2.4	5.1	1.5	1.5	1.7	1.8	1.8	0.5	1.5	-0.4	1.4	1.8	1.3	1.5	2.2	2.2	1.7
Had major operations	2.0	2.4	5.5	1.6	1.4	1.5	1.5	1.8	1.3	1.0	1.6	2.3	1.5	2.0	0.8	1.4	1.8	1.6
Medication: Aspirin	2.0	2.6	5.2	-1.7	-1.6	-1.7	-2.3	-2.0	-0.9	-1.6	0.3	-1.1	-1.9	-1.5	-1.5	-2.0	-1.9	-1.9
Past tobacco smoking	1.9	3.5	6.6	-1.7	-2.0	-2.1	-2.2	-2.2	-2.4	-2.2	-0.0	-2.6	-1.9	-1.1	-1.5	-1.5	-1.5	-2.3
Medication: Blood pressure	1.9	3.4	14.3	-1.4	-1.6	-1.3	-1.8	-1.9	-1.3	-2.0	3.8	-1.9	-1.5	-0.5	-2.4	-2.3	-1.3	-1.7
Long-standing illness, disability or infirmity	1.9	2.9	4.8	-2.0	-1.9	-2.0	-1.8	-1.9	-1.9	-2.2	0.2	-1.1	-1.9	-1.3	-1.1	-2.1	-1.9	-1.8
High cholesterol (Self-reported)	1.9	3.3	8.3	-0.9	-1.4	-1.6	-2.9	-1.9	-1.7	-1.1	1.6	-1.9	-1.5	-2.8	-1.4	-2.7	-1.6	-1.8
Basal cell carcinoma (self-reported)	1.9	2.2	6.2	1.5	1.3	1.5	2.0	1.6	1.7	1.5	2.5	1.1	1.4	1.0	1.0	1.8	1.1	1.5
Impedance of whole body	1.9	9.8	16.8	-4.0	-3.6	-3.9	-1.6	-3.8	-3.5	-3.7	-1.9	-3.7	-4.1	-0.5	-0.9	-2.4	-4.1	-3.6
Ever used hormone-replacement therapy (HRT)	1.8	2.3	4.1	1.3	1.6	1.4	0.8	1.7	1.4	2.0	1.6	1.8	1.3	1.9	2.0	1.5	1.0	1.6
Medication: Metformin	1.8	2.6	5.5	-1.6	-1.6	-1.9	-1.8	-1.9	-2.3	-0.9	-0.4	-2.4	-1.7	-0.6	-0.1	-2.1	-2.0	-1.6
Stomach or abdominal pain in last month	1.8	2.3	5.6	-1.5	-1.3	-1.5	-1.4	-1.6	-2.4	-1.7	1.7	-1.0	-1.5	-1.0	-2.2	-1.5	-1.1	-1.4
Medication: Cholesterol lowering	1.8	2.8	5.7	-1.1	-1.7	-1.4	-1.9	-1.9	-2.4	-1.5	1.2	-1.6	-1.4	-2.4	-1.5	-2.3	-1.7	-1.6
Eye problems/disorders: None of the above	1.8	2.1	4.8	1.7	1.5	1.8	1.1	1.4	1.3	2.0	-0.1	1.3	1.8	-0.1	2.2	1.1	1.1	1.8
Medication: Aspirin	1.8	2.3	6.1	-1.2	-1.4	-1.5	-2.5	-1.7	-0.9	-1.4	0.4	-1.1	-1.6	-1.9	-1.6	-1.9	-1.6	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	3.8	1.5	1.5	1.6	1.0	1.7	1.9	1.7	0.8	1.6	1.6	0.9	1.4	1.6	1.4	1.6
Frequency of depressed mood in last 2 weeks	1.7	2.4	4.2	-1.4	-1.5	-1.7	-1.3	-1.4	-1.1	-2.0	1.5	-1.2	-1.7	-1.9	-2.0	-2.0	-1.0	-1.8
Vitamin and mineral supplements	1.7	2.3	5.4	-2.2	-1.7	-1.9	-0.3	-2.2	-1.6	-1.3	0.3	-1.6	-2.1	-0.4	-0.9	-0.9	-2.3	-1.7
Multivitamins +/- minerals	1.7	2.1	5.4	2.3	1.7	1.9	0.2	2.0	0.7	1.5	0.7	1.4	2.1	-0.3	0.6	1.1	2.1	1.7
Hearing difficulty/problems with background noise	1.7	2.7	4.6	-1.4	-1.6	-1.6	-1.4	-1.6	-1.1	-2.1	1.9	-1.3	-1.6	-2.0	-2.2	-1.6	-1.8	-1.8
Qualifications: None of the above	1.7	3.7	8.0	-2.8	-2.1	-2.1	-1.3	-2.3	-2.3	-1.6	-1.1	-2.1	-2.3	0.5	-0.3	-2.3	-2.6	-1.9
Age at first live birth	1.7	3.0	13.1	-1.0	-1.6	-1.4	-0.8	-1.7	-1.0	-2.2	3.2	-1.5	-1.5	-1.0	-3.6	-0.9	0.1	-1.6
Depression (Nagel 2018)	1.6	2.4	6.9	-0.7	-1.2	-1.3	-1.8	-1.1	-1.3	-1.7	2.6	-1.3	-1.3	-2.0	-2.4	-2.1	-0.4	-1.5
Type 2 Diabetes (T2D) (2012)	1.6	1.9	4.3	-1.6	-1.4	-1.5	-1.0	-1.9	-1.8	-0.9	-0.9	-1.5	-1.6	-1.7	0.2	-0.8	-2.1	-1.2
Hypothyroidism (self reported)	1.6	3.6	8.0	-1.2	-1.9	-1.7	-2.8	-2.4	-1.8	-2.0	0.6	-2.1	-1.7	-2.7	-2.0	-2.3	-0.3	-2.0
Age when periods started (menarche)	1.6	3.9	9.1	-2.2	-1.6	-2.2	-2.3	-2.4	-3.0	-1.3	-0.8	-2.4	-2.4	-1.2	-0.7	-2.3	-2.5	-1.7
Major Depression (MDD)	1.5	1.8	5.8	0.8	0.8	1.0	1.4	0.8	1.9	1.0	2.3	1.5	0.9	2.4	-0.8	0.7	2.0	1.0
Lupus	1.5	2.2	5.4	-1.7	-1.3	-1.5	-2.0	-0.8	0.2	-2.3	-1.8	-1.1	-1.2	-0.6	-0.4	-2.1	-2.2	-1.8
Hearing difficulty/problems: Yes	1.5	2.3	8.6	-0.9	-1.4	-1.4	-1.5	-1.1	-0.4	-1.9	1.7	-1.2	-1.2	-2.9	-2.0	-1.0	-1.4	-1.9
Financial difficulties in last 2 years	1.5	2.0	5.7	1.6	1.4	1.4	1.0	1.4	2.2	1.1	-1.5	0.9	1.4	1.4	1.1	1.0	2.4	1.3
Alcohol intake versus 10 years previously	1.5	2.2	5.8	-1.2	-1.6	-1.5	-1.6	-1.5	-2.0	-0.7	-1.4	-1.6	-1.5	-2.4	0.2	-1.6	-1.7	-1.3
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.8	4.0	-1.2	-1.6	-1.4	-1.3	-1.5	-1.2	-2.0	0.6	-0.8	-1.4	-1.4	-1.8	-1.6	-0.6	-1.5
Migraine (self-reported)	1.5	1.8	3.9	-1.3	-1.6	-1.3	-0.2	-1.8	-1.5	-1.6	2.0	-1.1	-1.4	-1.2	-1.7	-1.3	-0.4	-1.4
Heart disease (mother)	1.5	1.8	3.1	-1.7	-1.7	-1.5	-1.4	-1.2	-0.2	-1.8	-1.4	-1.2	-1.5	-0.8	-1.4	-1.7	-1.1	-1.5
Eye problems/disorders: Cataract	1.5	1.8	3.2	-1.6	-1.4	-1.8	-1.1	-1.2	-1.5	-1.6	-1.1	-0.9	-1.7	-0.3	-1.2	-1.3	-1.3	-1.8
Unable to work because of sickness or disability	1.5	1.9	3.3	-1.6	-1.5	-1.4	-0.5	-1.7	-1.3	-1.8	-1.4	-1.8	-1.5	-0.5	-0.2	-1.8	-1.8	-1.4
Age at First Birth	1.4	2.0	6.6	1.3	1.0	1.2	1.2	1.1	2.1	0.5	2.6	1.6	1.1	1.3	-1.2	1.8	1.9	1.0
Leg predicted mass (left)	1.4	7.3	15.9	3.0	2.8	3.2	1.2	3.5	4.0	2.7	-2.3	3.4	3.4	1.4	2.4	2.2	2.2	2.8
Worry too long after embarrassment	1.4	2.4	13.4	-1.4	-1.3	-1.3	-0.8	-1.0	-1.1	-1.3	3.7	-1.1	-1.2	-0.9	-2.5	-1.6	-0.5	-1.0
Medication: Gliclazide	1.4	1.6	5.1	-0.8	-0.9	-1.1	-1.6	-0.9	-2.2	-1.4	1.6	-0.8	-0.9	-0.5	-2.1	-1.5	-0.6	-0.9
Tinnitus: Yes, now most or all of the time	1.4	1.7	6.2	1.6	1.4	1.2	1.0	1.8	-0.3	1.4	2.5	1.4	1.3	-0.2	0.4	1.6	0.6	1.2
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	4.2	1.3	1.3	1.4	1.7	1.3	-0.1	1.1	-0.4	1.4	1.5	1.2	1.1	2.0	1.6	1.3
Fasting Glucose	1.3	1.5	5.9	1.3	1.2	1.1	1.0	1.3	1.8	1.1	2.4	1.0	1.4	0.2	1.0	1.1	0.8	1.2
HDL Cholesterol	1.3	2.2	6.9	1.3	1.5	1.4	1.7	1.0	1.8	1.1	2.1	1.4	1.3	2.6	0.9	1.3	1.2	1.5
Leg fat-free mass (left)	1.3	7.1	15.8	3.0	2.8	3.2	1.2	3.4	4.0	2.6	-2.3	3.4	3.4	1.3	2.3	2.2	2.2	2.7
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	5.3	1.0	1.1	1.0	-0.2	1.2	1.1	1.3	-2.3	0.5	1.2	-0.1	2.3	1.3	0.2	1.1
Noisy workplace	1.3	1.6	3.4	-1.8	-1.6	-1.6	-1.0	-1.6	-0.4	-1.7	0.3	-1.1	-1.5	-0.7	-1.2	-1.2	-1.4	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	1.9	7.5	1.7	1.2	1.3	1.9	1.6	-0.0	0.6	2.7	1.3	1.5	1.2	0.2	0.8	1.9	1.3
Mineral and other dietary supplements	1.3	1.7	4.3	-2.1	-1.5	-1.7	0.2	-1.6	-1.0	-0.6	0.2	-1.4	-1.9	-1.3	-0.6	-1.3	-1.6	-1.3
Medication: Lisinopril	1.3	1.6	4.2	1.3	1.4	1.5	1.4	1.2	1.1	1.0	1.2	2.1	1.5	1.0	0.9	0.9	1.3	1.4
Heel T-Score	1.2	9.9	18.3	3.6	3.3	3.5	2.6	4.3	4.0	2.8	2.9	3.0	3.7	1.9	2.3	4.3	2.5	3.1
Taking other prescription medications	1.2	1.8	3.2	-1.3	-1.3	-1.3	-1.5	-1.5	-1.4	-1.8	1.6	-1.3	-1.2	0.1	-1.3	-1.5	-1.6	-1.4
Worrier / anxious feelings	1.2	2.2	8.1	-1.0	-0.9	-1.1	-1.3	-1.2	-1.4	-1.6	2.8	-1.8	-1.0	-0.6	-2.2	-2.2	-1.1	-1.0
Forced vital capacity (FVC), Best measure	1.2	4.5	7.8	2.7	2.7	2.7	0.7	2.1	2.1	2.8	-1.9	1.8	2.6	0.2	2.0	1.9	2.5	2.5
Number of children fathered	1.2	1.4	2.8	-1.7	-1.4	-1.4	0.3	-1.0	-1.0	-1.3	0.7	-0.8	-1.5	-0.3	-1.6	-1.4	-1.1	-1.4
Qualifications: College or University degree	1.2	3.9	8.3	1.9	1.9	1.6	2.4	2.4	2.9	0.9	2.7	2.3	1.9	1.3	-0.8	2.5	2.4	1.6
Comparative height size at age 10	1.2	6.8	40.2	-2.8	-2.2	-2.2	-2.5	-2.3	0.7	-2.4	-6.3	-2.0	-2.3	-0.9	0.5	-2.4	-3.2	-2.6
Leg predicted mass (right)	1.2	6.3	15.2	2.8	2.6	2.9	1.1	3.3	3.9	2.4	-2.0	3.1	3.1	1.2	2.1	2.2	2.1	2.5
Current tobacco smoking	1.1	1.7	4.3	-1.4	-1.4	-1.5	-0.7	-1.3	-1.1	-1.1	-1.6	-1.1	-1.3	-2.1	-0.3	-1.5	-1.5	-1.6
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	4.4	1.6	1.4	1.3	0.7	1.0	0.3	1.7	-0.6	1.8	1.3	-2.1	1.0	1.2	1.4	1.4
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	2.9	-1.7	-1.6	-1.3	-0.9	-1.3	-0.1	-0.3	-0.9	-1.3	-1.5	0.5	0.9	-1.4	-1.7	-0.9
Commuting to job workplace: Car/motor vehicle	1.1	1.2	2.8	-1.1	-1.2	-1.1	-1.5	-1.1	-0.6	-1.3	0.5	-1.7	-1.0	-0.3	-1.4	-1.3	-1.2	-1.3
Leg fat-free mass (right)	1.1	6.1	15.1	2.7	2.5	2.9	1.0	3.2	3.9	2.3	-2.1	3.1	3.0	1.1	2.0	2.1	2.0	2.4
Qualifications: nursing, teaching	1.1	1.8	4.4	1.7	1.2	1.3	1.4	2.1	0.9	0.4	-0.6	1.5	1.7	1.6	0.1	2.1	0.9	1.1
Number of operations (self-reported)	1.1	1.6	4.4	1.0	1.4	1.1	1.7	1.7	0.3	1.3	-0.2	1.3	1.2	2.1	1.7	1.5	0.6	1.1
Height	1.0	20.0	63.7	-4.7	-4.6	-4.3	-5.4	-3.4	-1.8	-4.8	-8.0	-3.3	-4.3	-2.6	-1.9	-4.5	-6.5	-5.0
Chronic bronchitis/emphysema (father)	1.0	1.1	2.0	1.4	1.2	1.4	0.1	1.3	1.3	1.0	-0.3	1.1	1.4	0.5	1.1	0.7	1.3	1.3
Body mass index (BMI)	1.0	4.1	9.8	2.1	2.1	2.4	1.3	2.3	3.1	1.9	0.3	2.8	2.5	1.4	1.8	1.5	1.9	2.4
Medication for pain relief, constipation, heartburn	1.0	1.7	4.1	0.9	1.1	1.0	1.9	1.2	2.0	1.1	0.1	1.2	1.1	2.0	1.0	2.0	0.5	1.2
Neck or shoulder pain in last month	1.0	1.4	3.9	-1.4	-1.0	-1.1	-0.9	-1.2	-1.2	-1.1	0.7	-1.1	-1.2	-1.8	-1.0	-2.0	-0.7	-1.0
Arm fat percentage (left)	1.0	3.8	8.6	1.4	1.7	2.0	2.1	2.0	2.9	1.3	-0.9	2.9	2.0	2.1	2.8	1.9	0.8	2.0
Financial situation satisfaction	1.0	1.3	4.4	1.5	1.4	1.2	0.2	1.2	0.8	1.4	0.1	0.9	1.3	-1.0	0.8	1.0	2.1	1.2
Alcohol drinker status: Never	1.0	1.2	3.3	-1.4	-1.0	-1.3	0.1	-1.0	-1.2	-0.6	-1.8	-1.3	-1.2	0.1	1.3	-0.2	-1.3	-1.1
Irritability	1.0	1.7	11.4	-0.7	-0.7	-1.0	-0.7	-0.4	1.2	-1.2	3.4	-1.0	-0.7	-1.1	-2.1	-1.6	-0.4	-0.9
Alzheimer’s Disease (in father)	0.9	0.9	2.1	1.0	1.0	1.1	1.1	1.2	1.0	1.4	0.3	1.0	1.0	0.3	1.2	0.6	0.8	1.1
BMI	0.9	5.2	17.5	2.5	2.5	2.6	1.8	2.6	4.2	1.9	1.1	2.6	2.8	1.0	1.4	1.5	2.3	2.6
Sitting height	0.9	6.4	11.5	-3.1	-3.1	-2.9	-2.3	-2.5	-0.4	-3.1	-3.0	-2.0	-2.8	-0.8	-3.1	-2.3	-2.6	-3.4
Arm fat percentage (right)	0.9	3.6	8.2	1.4	1.6	1.9	2.0	2.0	2.8	1.2	-1.2	2.9	1.9	2.0	2.8	1.8	0.7	1.9
Asthma	0.9	1.8	3.7	-1.5	-1.4	-1.2	-0.7	-1.9	-1.5	-1.2	1.9	-0.9	-1.3	-0.2	-1.7	-1.8	-1.4	-1.0
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	3.2	1.4	1.4	1.3	0.6	1.2	1.8	1.1	0.6	-0.1	1.4	0.4	1.0	1.2	1.0	1.1
Medication: Ibuprofen	0.9	1.1	5.3	-0.0	-0.3	-0.1	-0.8	-0.5	-1.9	-0.3	1.5	-0.8	-0.2	-2.3	-1.8	-1.0	0.2	-0.3
Asthma (self-reported)	0.9	1.7	4.3	-1.5	-1.4	-1.2	-0.7	-1.9	-1.2	-1.2	2.1	-0.9	-1.3	-0.2	-1.7	-1.8	-1.2	-1.0
Eye problems/disorders: Glaucoma	0.9	1.0	2.6	-1.1	-1.0	-1.0	-1.5	-0.9	0.0	-1.6	-0.1	-1.1	-1.0	-0.4	-1.4	-0.6	-1.3	-1.2
Supplements: Calcium	0.9	1.0	3.8	0.9	0.6	1.0	1.1	1.2	1.2	-0.1	-0.7	1.4	1.2	1.9	0.7	0.9	0.1	0.8
Rheumatoid Arthritis	0.8	1.1	5.5	-0.4	-0.2	-0.3	-1.4	-0.8	-1.1	-0.9	2.3	-1.5	-0.2	-0.9	-1.2	-1.3	-0.9	-0.4
Medication: Co-codamol	0.8	0.9	2.6	-1.6	-0.9	-1.2	-0.4	-0.8	-1.3	-1.1	0.2	-0.9	-1.1	-0.1	0.0	-1.4	-1.1	-0.8
Relative age voice broke	0.8	1.3	3.5	0.6	1.2	1.0	1.1	1.6	0.5	1.2	-1.0	1.9	1.1	0.7	0.2	1.6	1.1	1.3
Had other major operations	0.8	1.0	5.5	0.5	0.9	0.6	1.6	0.5	1.7	0.3	-0.8	0.5	0.7	2.3	0.7	1.4	-0.4	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	4.9	-1.2	-1.0	-1.3	-1.2	-1.0	-0.9	-1.5	0.5	-0.9	-1.1	-1.0	-1.0	-2.2	-0.6	-1.0
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	6.4	2.4	2.1	2.1	0.3	1.7	0.3	2.5	-1.1	0.9	2.0	-0.3	1.4	1.2	2.5	2.0
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	7.3	0.3	-0.1	0.1	-0.8	-0.3	-1.7	0.0	1.3	-0.6	0.0	-2.7	-1.5	-0.9	0.3	-0.1
Birth weight	0.8	1.7	10.5	1.0	0.7	0.9	1.4	1.6	3.2	0.7	-0.2	1.4	1.1	1.3	0.6	1.5	1.0	0.8
Loneliness, isolation	0.8	1.1	3.8	-0.4	-0.3	-0.6	-1.6	-0.5	-0.4	-0.9	1.8	-1.2	-0.4	-2.0	-1.3	-1.8	-0.2	-0.6
Commuting to job workplace: Walk	0.8	0.9	2.9	0.4	0.6	0.7	1.6	0.4	0.0	1.0	-1.2	1.0	0.5	1.1	1.7	1.1	0.7	0.9
Average weekly champagne plus white wine intake	0.8	1.1	7.2	0.8	0.9	0.8	0.4	1.5	2.7	0.3	0.9	1.2	1.0	-0.4	-0.1	1.0	0.3	0.6
Medication: Simvastatin	0.7	1.0	3.1	1.8	1.1	1.2	0.2	1.0	0.1	1.3	0.7	1.4	1.4	0.2	1.1	0.3	0.6	1.1
Illnesses of mother	0.7	0.8	2.1	1.2	0.8	1.2	0.3	1.1	0.5	0.7	-0.1	1.5	1.1	0.5	0.3	1.3	1.0	1.1
Arm fat mass (right)	0.7	3.0	8.8	1.3	1.4	1.8	1.1	1.9	3.0	1.2	-1.7	2.5	1.9	1.5	2.4	1.2	0.7	1.7
Standing height	0.7	7.3	50.0	-2.3	-2.4	-2.2	-3.1	-1.5	-0.1	-2.2	-7.1	-1.7	-2.2	-1.6	-0.3	-1.9	-3.3	-2.8
Breastfed as a baby	0.7	0.8	3.0	-1.0	-0.5	-0.8	-1.5	-1.0	-0.8	0.2	-0.3	-0.9	-0.9	-1.7	0.0	-1.1	-0.8	-0.6
Emphysema/chronic bronchitis	0.7	0.8	3.3	1.1	0.9	1.2	0.9	0.4	0.7	0.4	0.8	0.6	1.1	1.8	0.5	0.2	1.2	1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	15.1	-0.5	-0.7	-0.5	-1.1	-0.7	-0.7	-0.0	-3.9	-0.8	-0.7	-2.0	0.9	-0.4	-0.5	-0.4
Smoking status: Current	0.7	1.2	3.5	-1.1	-1.2	-1.3	-0.5	-1.0	-0.8	-1.1	-1.3	-0.7	-1.1	-1.9	-0.4	-1.1	-1.0	-1.4
Arm fat mass (left)	0.7	3.1	8.9	1.3	1.5	1.8	1.2	1.9	3.0	1.3	-1.7	2.6	1.9	1.6	2.3	1.3	0.7	1.8
Guilty feelings	0.7	1.0	7.4	0.7	0.9	0.7	0.7	1.4	0.5	0.1	2.7	1.0	0.9	0.9	-0.3	-0.3	0.8	0.7
Commuting to job workplace: Public transport	0.7	0.8	2.7	0.6	0.7	0.8	0.4	1.0	0.8	0.7	-1.0	1.6	0.8	0.1	1.4	0.7	1.1	0.9
Diastolic blood pressure, automated reading	0.7	2.3	6.5	-1.1	-2.0	-1.5	-1.9	-1.5	-1.8	-1.9	1.2	-0.5	-1.5	-0.4	-2.5	-1.2	-0.9	-1.9
Ulcerative Colitis (UC)	0.6	1.2	5.2	-0.4	-0.6	-0.7	-1.6	-0.5	-2.0	-1.0	-0.5	-1.2	-0.7	0.0	-1.5	-2.3	-0.0	-0.8
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.5	-0.8	-0.8	-0.9	-0.2	-1.2	-0.9	-0.2	-1.6	-1.1	-1.0	-0.3	0.4	-0.5	-1.0	-0.7
Supplements: Zinc	0.6	0.7	1.8	0.8	0.6	0.7	0.6	0.8	0.4	1.1	0.1	1.3	0.9	0.4	1.0	1.3	0.8	0.9
Qualifications: CSEs or equivalent	0.6	0.8	6.2	0.0	-0.3	-0.1	-0.8	-0.7	-1.3	-0.0	-2.5	-0.9	-0.2	-0.9	1.0	-0.9	0.1	-0.1
Number of incorrect matches in round	0.6	1.0	3.2	0.8	1.2	0.8	1.0	0.8	1.7	1.0	-0.1	0.1	0.8	1.8	1.6	0.9	0.5	0.9
Impedance of arm (right)	0.6	2.7	8.0	-2.0	-1.5	-1.8	0.7	-1.5	-1.4	-1.8	-2.7	-1.1	-1.9	0.7	1.5	-0.1	-2.8	-1.7
Qualifications: A levels/AS levels or equivalent	0.6	1.3	7.3	0.9	0.7	0.6	1.2	1.4	2.7	0.4	0.8	1.5	0.8	-0.1	-0.1	1.8	1.4	0.4
Hair/balding pattern: Pattern 4	0.6	1.4	3.0	1.2	1.7	1.4	0.6	1.1	1.7	0.8	-0.5	0.6	1.5	1.4	1.3	1.5	0.3	1.3
Glaucoma (self-reported)	0.6	0.7	2.0	-1.0	-1.1	-0.9	-1.0	-0.5	0.0	-1.3	0.2	-0.7	-0.8	-0.1	-1.1	-0.2	-1.4	-1.1
Number of full brothers	0.6	0.7	2.1	1.1	0.7	0.8	1.4	0.7	0.5	0.6	0.1	0.0	1.0	0.9	1.1	1.0	1.2	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.6	-1.0	-0.5	-0.7	0.3	-1.2	-1.3	-0.8	1.0	-0.7	-0.8	-0.5	-0.7	-0.9	-1.3	-0.5
Age at last live birth	0.6	0.9	4.8	-0.3	-0.7	-0.6	-0.9	-0.8	-0.2	-1.2	1.9	-0.9	-0.7	0.1	-2.2	-0.6	0.5	-0.8
Osteoarthritis (self-reported)	0.6	0.8	2.8	0.4	0.6	0.6	1.2	1.3	1.7	0.0	1.0	1.0	0.8	1.2	0.3	0.7	0.5	0.6
Hearing aid user	0.6	0.7	3.3	-0.8	-0.9	-1.0	0.1	-0.9	0.1	-0.5	1.8	-0.1	-1.1	-0.7	-0.9	-0.3	-0.5	-0.9
Depressed Affect (Nagel 2018)	0.5	1.0	4.8	-0.1	-0.2	-0.5	-1.0	0.2	-1.1	-1.0	2.2	-0.6	-0.2	-1.0	-1.8	-1.9	0.2	-0.4
LDL Cholesterol	0.5	0.8	5.0	0.3	-0.0	-0.2	-1.2	-0.3	-0.7	-0.8	2.2	-0.6	-0.1	0.1	-1.7	-1.2	0.2	-0.4
Neuroticism (2016)	0.5	0.8	3.4	1.0	0.9	0.7	-0.2	0.7	-0.1	0.2	1.7	-0.4	0.6	-0.5	-1.1	-0.9	1.9	0.5
Blood Platelet Count	0.5	5.8	17.4	-1.3	-2.2	-2.1	-2.1	-3.0	-1.5	-1.9	3.5	-2.7	-2.1	-4.2	-3.0	-2.4	-1.4	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	3.0	0.7	0.9	0.9	0.9	1.7	0.5	1.0	0.4	0.7	1.0	1.5	1.3	1.7	0.6	1.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.5	2.3	0.6	0.7	0.5	1.2	0.5	-0.1	0.5	0.2	0.3	0.7	1.5	1.4	0.4	-0.5	0.5
Weight	0.5	2.3	9.2	1.0	1.0	1.4	0.0	1.6	3.0	0.9	-2.8	2.0	1.5	0.8	1.6	0.7	0.4	1.1
Lung cancer (father)	0.5	0.6	1.5	-1.1	-0.7	-0.8	-0.4	-1.0	0.1	-0.1	-1.0	-1.0	-0.8	0.2	0.6	-0.9	-1.2	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	3.5	1.8	1.5	1.5	-0.4	1.0	0.9	1.9	-1.7	-0.1	1.4	-1.1	1.1	0.7	1.8	1.3
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	4.0	-0.1	-0.7	-0.6	-2.0	-1.3	-0.9	-0.8	1.4	-0.8	-0.6	-1.0	-1.1	-1.4	0.6	-0.8
Wheeze or whistling in the chest in last year	0.5	0.9	3.6	-0.8	-0.8	-0.7	-0.2	-1.2	-0.3	-1.1	1.1	-0.4	-0.7	-1.1	-1.9	-1.4	-0.7	-0.7
Medication: Allopurinol	0.5	0.6	1.7	-0.9	-1.0	-0.9	-0.6	-0.1	-0.7	-0.4	1.3	0.1	-0.9	0.3	-0.6	-1.2	-1.3	-0.8
Number of full sisters	0.5	0.6	4.2	-0.2	-0.6	-0.2	-1.1	-1.2	0.0	0.3	-2.0	-0.9	-0.5	-0.0	1.0	0.2	-0.4	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	4.1	-0.3	-0.5	-0.5	-0.4	-0.1	-0.8	-0.4	2.0	-0.9	-0.5	-0.1	-0.7	-0.9	0.2	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.7	0.6	0.8	1.0	0.2	0.6	0.9	0.9	-0.1	0.6	0.8	0.6	-0.1	0.8	1.3	0.9
Ever depressed for a whole week	0.5	0.6	2.9	0.9	0.5	0.5	0.7	0.1	-1.4	0.3	-0.5	0.5	0.6	1.7	0.8	-0.1	0.8	0.6
Cholesterol lowering medication	0.5	0.8	4.5	0.2	0.2	-0.3	-2.1	-0.3	-1.0	0.6	1.1	-0.7	-0.3	-1.8	-0.1	-1.2	-0.4	-0.3
Smoking Status	0.4	1.1	2.4	1.2	1.0	1.2	1.2	1.4	0.2	1.0	-0.7	1.3	1.2	-0.9	0.7	0.2	1.6	1.2
Respiratory disease	0.4	1.0	3.1	-1.2	-1.0	-0.8	-0.7	-1.5	-0.8	-0.9	0.9	-0.4	-1.0	-0.2	-1.4	-1.8	-0.6	-0.7
Chronotype (morning person)	0.4	0.9	4.9	1.0	0.2	0.5	0.5	1.1	-2.2	0.2	0.3	-0.6	0.9	1.3	0.3	1.8	-0.2	0.4
Diabetes (father)	0.4	0.5	1.6	-0.7	-0.4	-0.4	-1.3	-1.1	-0.1	-0.8	0.1	-1.2	-0.6	0.3	-0.7	-1.1	-0.7	-0.5
Serious illness, injury or assault to yourself	0.4	0.5	2.3	-0.6	-0.9	-0.7	-0.0	-0.6	-0.8	-1.0	0.3	-0.8	-0.5	-1.5	-0.4	-0.4	0.4	-0.5
Impedance of arm (left)	0.4	1.6	4.2	-1.6	-1.1	-1.3	1.1	-1.0	-0.8	-1.3	-1.9	-0.7	-1.5	1.3	1.6	0.5	-2.1	-1.1
Medication: Paracetamol	0.4	0.7	1.9	-0.9	-0.9	-0.8	-1.2	-0.7	-1.4	-0.8	0.2	-0.7	-0.8	-0.7	-0.8	-1.4	-0.4	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.5	0.3	0.6	0.4	1.2	0.4	-0.1	1.0	0.6	0.5	0.3	0.5	0.7	1.2	-0.3	0.5
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.1	-0.3	-0.3	-0.5	-1.1	-0.7	-1.0	-0.5	0.4	-0.6	-0.5	-0.8	-0.8	-0.9	-0.8	-0.4
Illnesses of father: Heart disease	0.4	0.6	2.0	-0.7	-1.0	-0.8	-0.4	-0.3	-1.0	-0.9	1.4	0.0	-0.6	0.4	-0.8	-1.0	-0.6	-0.8
Whole body fat-free mass	0.4	2.4	8.1	1.6	1.3	1.6	-0.5	2.0	2.8	1.3	-2.8	1.9	1.8	-0.2	0.8	0.6	0.9	1.1
Friendships satisfaction	0.4	0.5	2.6	-0.1	-0.3	-0.5	-1.0	-0.1	-0.1	-0.6	0.7	-0.1	-0.3	-1.6	-1.3	-0.9	-0.3	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	3.6	1.6	1.0	1.0	0.2	0.8	0.5	0.7	1.2	0.2	1.0	0.4	-0.7	0.6	1.9	0.7
Whole body water mass	0.4	2.3	7.7	1.5	1.3	1.6	-0.4	2.0	2.7	1.3	-2.8	1.9	1.8	-0.2	0.9	0.7	1.0	1.1
Illnesses of father: High blood pressure	0.4	0.5	1.5	0.7	0.5	0.8	0.7	1.2	0.5	1.2	0.7	0.5	0.8	0.2	0.8	0.3	0.3	1.0
Basal metabolic rate	0.4	2.5	8.8	1.5	1.3	1.6	-0.4	2.0	3.0	1.2	-2.9	1.9	1.8	0.0	1.0	0.7	0.9	1.1
Average weekly beer plus cider intake	0.4	0.6	3.2	0.6	0.3	0.7	0.0	0.9	0.2	0.3	1.8	0.6	0.9	-0.8	-1.1	0.6	0.2	0.7
Commuting to job workplace: Cycle	0.4	0.5	2.9	-0.1	-0.2	-0.4	-0.2	-0.1	-0.7	0.0	1.7	-0.2	-0.4	-1.0	-1.4	-0.1	0.9	-0.3
Ulcerative Colitis	0.3	0.5	2.2	0.5	0.4	0.1	-1.1	0.3	-0.6	-0.1	1.1	-0.7	0.1	0.2	-1.0	-1.5	0.9	0.0
Hair Pigment	0.3	7.8	15.2	3.9	3.1	3.3	2.9	2.6	2.0	3.5	1.3	2.7	3.3	-0.5	2.2	3.1	3.6	3.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	2.6	0.4	0.5	0.4	1.6	-0.1	-0.2	0.3	-0.7	0.7	0.5	0.3	0.4	0.5	1.2	0.6
Ever had hysterectomy (womb removed)	0.3	0.3	2.4	-0.1	0.1	-0.3	-0.9	-0.5	-0.3	0.2	-0.3	-1.0	-0.3	0.0	1.6	-0.7	-0.1	-0.3
Severe depression (siblings)	0.3	0.3	0.7	0.8	0.5	0.7	0.5	0.7	0.4	0.2	0.7	0.6	0.8	0.6	-0.1	0.3	0.7	0.7
Trunk fat percentage	0.3	1.1	4.7	-0.4	-0.2	0.1	0.3	0.1	1.7	-0.5	-2.2	0.9	0.1	1.6	2.0	0.3	-1.1	0.1
Average weekly fortified wine intake	0.3	0.3	1.7	0.4	0.3	0.3	0.6	0.6	0.8	0.3	-0.1	1.3	0.2	-1.0	0.0	-0.0	0.9	0.2
High blood pressure (mother)	0.3	0.4	1.2	-0.5	-0.2	-0.6	0.6	-0.9	-0.4	-0.1	0.8	-1.1	-0.6	-1.1	-0.2	-0.4	-0.5	-0.6
Trunk fat mass	0.3	1.3	7.8	-0.0	0.1	0.5	0.0	0.5	2.3	-0.2	-2.8	1.2	0.5	1.3	1.9	0.3	-0.7	0.4
Had menopause	0.3	0.3	1.3	-0.2	0.1	0.0	-0.6	0.2	0.9	0.0	-1.1	0.5	-0.0	0.9	1.1	0.2	-0.7	0.1
Illnesses of siblings	0.3	0.5	1.3	0.3	0.8	0.5	1.0	0.7	1.2	1.1	0.1	0.7	0.5	0.9	0.2	0.4	0.0	0.9
Father’s age at death	0.3	0.4	1.7	0.5	0.4	0.5	1.1	0.1	1.1	0.4	-0.4	0.1	0.4	0.4	0.5	1.3	0.6	0.4
Prospective memory result	0.3	0.3	1.1	-0.7	-0.1	-0.4	0.1	-0.4	1.0	-0.0	-1.0	-0.7	-0.4	0.8	1.0	0.1	-0.6	-0.3
Trunk predicted mass	0.3	1.5	9.0	0.9	0.6	0.9	-1.1	1.4	2.2	0.8	-3.0	1.2	1.1	-0.9	0.1	-0.0	0.4	0.4
Peak expiratory flow (PEF)	0.3	0.7	3.4	0.7	0.8	0.6	-0.2	0.0	-0.7	1.3	-1.8	-0.5	0.4	-1.4	0.9	-0.2	0.8	0.7
Loud music exposure frequency	0.3	0.4	1.8	-0.6	-0.2	-0.1	0.9	0.2	0.8	0.1	-0.3	0.1	-0.2	1.3	1.0	0.3	-1.0	-0.2
Medication: Amlodipine	0.3	0.4	1.6	-0.8	-0.7	-0.5	0.0	-0.6	-0.7	-0.7	1.1	-0.6	-0.5	-0.2	-1.3	-0.9	-0.3	-0.4
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.4	-1.0	-0.7	-0.6	-0.0	-0.9	-1.2	-0.5	-0.1	0.4	-0.7	0.3	-0.2	-0.5	-0.8	-0.2
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.7	-0.0	0.3	0.2	0.9	0.6	0.5	0.3	1.0	0.6	0.4	1.3	0.7	0.4	0.1	0.4
High blood pressure (siblings)	0.3	0.4	2.1	0.8	0.5	0.7	0.1	0.2	-0.4	0.5	-0.1	1.0	0.6	0.9	0.5	0.1	1.5	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	3.3	0.3	0.1	0.0	0.1	0.5	-0.6	-0.7	1.8	0.3	0.4	0.4	-0.7	-0.3	1.1	0.1
Whole body fat mass	0.3	1.2	5.6	0.2	0.4	0.7	0.1	0.8	2.4	0.1	-2.2	1.3	0.7	1.3	1.8	0.4	-0.5	0.6
Family relationship satisfaction	0.3	0.4	3.1	-0.1	-0.2	-0.5	-1.1	-0.4	0.2	-0.3	-0.4	-0.0	-0.3	-1.8	-0.8	-0.3	0.1	-0.6
Breast cancer (self-reported)	0.3	0.3	1.7	-0.5	0.2	-0.1	-0.7	0.2	1.3	0.6	-1.3	0.1	-0.1	-0.7	-0.1	-0.3	-0.7	0.2
Illnesses of father: None of the above (group 1)	0.3	0.4	3.5	0.0	0.4	0.1	0.7	-0.0	0.1	0.6	-1.9	0.3	0.0	0.5	0.7	1.0	0.5	0.2
Miserableness	0.3	0.5	4.1	0.3	0.4	0.1	-0.1	0.6	-1.0	-0.3	2.0	0.2	0.2	0.3	-0.9	-1.1	0.5	0.2
Wears glasses or contact lenses	0.3	0.3	0.8	-0.9	-0.9	-0.7	-0.1	-0.1	0.7	-0.6	0.6	0.2	-0.6	0.7	-0.3	-0.1	-0.5	-0.7
Supplements: Fish oil (including cod liver oil)	0.3	0.5	1.4	1.1	0.8	0.8	-1.1	0.4	0.3	0.1	0.4	0.3	0.9	0.5	-0.5	0.0	1.2	0.5
Medication: Paracetamol	0.3	0.4	1.3	-0.7	-0.8	-0.6	-0.9	-0.3	-0.8	-0.6	-0.4	-0.4	-0.6	-0.4	-0.5	-1.2	-0.1	-0.7
Ever smoked	0.3	0.6	3.5	0.2	0.7	0.6	1.0	1.0	1.9	0.9	-0.0	1.1	0.5	-0.4	0.4	0.2	-0.0	0.8
Leg fat percentage (left)	0.3	1.1	2.6	-1.5	-1.2	-1.1	-1.1	-1.3	0.2	-1.4	-0.8	-0.3	-1.2	0.1	0.1	-1.4	-1.6	-1.0
Risk taking	0.3	0.5	1.7	0.3	0.1	0.3	1.1	0.8	0.6	-0.1	0.5	1.3	0.4	0.5	-0.8	1.0	0.9	0.1
Fractured/broken bones in last 5 years	0.3	0.4	1.3	0.4	0.3	0.6	1.0	1.1	0.4	-0.1	-0.6	0.9	0.6	1.0	0.1	0.1	0.5	0.6
Crohns Disease (2017)	0.2	0.5	2.8	0.7	0.6	0.7	0.9	0.8	-0.4	0.7	1.7	0.9	0.8	0.6	-0.2	0.0	0.4	0.7
Irritable Bowel Disease (IBD)	0.2	0.5	2.3	0.2	0.0	-0.1	-0.8	0.2	-1.2	-0.4	1.1	-0.4	0.0	0.3	-1.5	-1.5	0.2	-0.2
Mean Putamen Volume	0.2	0.3	1.5	0.0	-0.0	-0.1	-0.3	0.0	0.5	-0.1	1.2	0.1	-0.0	-0.8	-1.2	-0.6	0.3	-0.1
Hand grip strength (left)	0.2	0.7	2.6	1.0	0.4	0.7	-0.7	-0.1	0.6	0.7	1.0	0.4	0.6	-0.7	-1.5	-0.6	1.6	0.5
Relative age of first facial hair	0.2	0.5	1.9	-0.0	0.3	0.3	1.0	0.9	-0.4	1.0	-0.8	1.4	0.3	-0.3	0.1	1.1	0.1	0.5
Medication for hormone replacement therapy	0.2	0.2	0.7	0.4	0.3	0.4	-0.6	0.4	-0.2	0.8	-0.6	0.5	0.4	0.3	0.4	0.3	0.7	0.5
Hand grip strength (right)	0.2	0.4	1.4	0.7	0.5	0.6	-0.5	0.2	0.7	0.9	0.5	0.6	0.5	-0.4	-1.1	-0.7	1.2	0.5
Waist circumference	0.2	0.8	6.8	-0.5	-0.8	-0.4	-1.3	-0.1	0.4	-0.7	-2.6	0.3	-0.3	-0.4	0.4	-0.8	-1.3	-0.5
Trunk fat-free mass	0.2	1.4	9.1	0.8	0.5	0.8	-1.2	1.3	2.2	0.7	-3.0	1.1	1.0	-0.9	0.0	-0.1	0.3	0.3
Hair/balding pattern: Pattern 3	0.2	0.3	1.2	0.6	0.5	0.4	0.7	0.6	0.5	0.8	1.1	0.4	0.5	0.2	-0.0	0.9	0.4	0.3
Medication: Lansoprazole	0.2	0.2	0.9	0.1	0.1	0.1	0.3	-0.2	-0.8	0.3	0.9	-0.6	-0.2	-0.2	0.6	-0.8	-0.3	-0.1
Pulse wave Arterial Stiffness index	0.2	0.2	1.7	0.3	0.5	0.4	-0.1	-0.5	-0.0	0.8	-0.6	-0.3	0.1	0.1	1.3	0.2	-0.3	0.5
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.2	-0.4	-0.4	-0.4	0.4	-0.0	-1.1	-0.4	0.3	-0.4	-0.2	0.2	-0.8	-0.1	-0.2	-0.2
Blood clot in the leg (DVT)	0.2	0.3	0.9	-0.4	-0.3	-0.4	-0.2	0.1	0.7	-0.6	0.9	-1.0	-0.2	0.5	-0.5	-0.1	-0.4	-0.6
Gout (self-reported)	0.2	0.3	1.6	-0.3	-0.2	-0.4	-0.5	0.3	0.0	0.1	1.2	0.2	-0.4	0.6	-0.2	-0.7	-0.7	-0.4
Body fat percentage	0.2	0.8	3.2	-0.5	-0.2	0.0	0.3	0.0	1.6	-0.5	-1.5	0.9	0.0	1.4	1.8	0.1	-1.0	0.1
Leg fat percentage (right)	0.2	0.7	1.5	-1.1	-1.0	-0.8	-1.0	-1.0	0.2	-1.1	-0.9	-0.0	-0.8	0.2	0.3	-1.2	-1.2	-0.7
Arm fat-free mass (right)	0.2	1.2	6.0	0.9	0.6	0.9	-1.4	1.1	2.1	0.7	-2.5	1.0	1.1	-0.4	-0.1	-0.2	0.7	0.4
Pulse wave peak to peak time	0.2	0.2	1.3	-0.4	-0.7	-0.5	-0.1	0.4	0.0	-0.9	0.1	0.2	-0.3	-0.2	-1.1	-0.3	0.0	-0.7
Shortness of breath walking on level ground	0.2	0.2	0.9	0.0	0.1	0.1	0.6	-0.2	-0.6	-0.6	0.8	0.9	0.1	0.6	-0.8	-0.0	-0.5	0.1
Leg fat mass (right)	0.2	0.8	4.1	0.4	0.4	0.7	-0.1	0.7	2.0	0.1	-1.6	1.2	0.8	0.9	1.2	0.1	-0.1	0.6
Arm predicted mass (right)	0.2	1.0	5.1	0.6	0.4	0.7	-1.4	0.8	2.0	0.6	-2.2	0.7	0.8	-0.8	-0.1	-0.4	0.3	0.3
Chest pain or discomfort	0.2	0.3	1.0	0.7	0.5	0.6	-0.1	-0.2	-0.2	1.0	-0.3	0.9	0.4	-0.6	0.8	0.2	0.6	0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.4	-0.2	0.3	-0.1	-0.1	0.3	0.7	0.2	-0.3	0.5	-0.1	1.0	0.4	0.4	-1.2	-0.1
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.7	-0.5	-0.4	-0.5	-0.1	0.1	-0.7	-0.4	0.5	-0.8	-0.4	-0.7	-0.5	-0.8	-0.7	-0.3
Mood swings	0.2	0.4	3.2	-0.2	0.1	-0.2	0.3	0.3	-0.6	-0.6	1.8	0.0	-0.0	0.7	-1.2	-1.0	0.1	0.0
Ever taken oral contraceptive pill	0.2	0.3	1.0	0.3	0.2	0.4	0.8	-0.2	0.8	0.4	0.6	0.0	0.3	-0.5	0.1	1.0	-0.6	0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.3	0.9	0.6	0.6	0.0	0.4	-0.3	0.3	1.1	0.0	0.8	-0.5	0.2	-0.0	0.4	0.4
Arm fat-free mass (left)	0.2	1.0	6.6	0.6	0.3	0.6	-1.5	0.9	1.6	0.4	-2.6	0.9	0.8	-0.7	-0.2	-0.6	0.2	0.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.0	-0.4	-0.2	-0.3	0.0	0.2	1.0	-0.6	1.0	-0.8	-0.1	0.7	-0.3	0.2	-0.6	-0.6
Leg fat mass (left)	0.2	0.7	4.0	0.3	0.3	0.6	-0.3	0.6	2.0	0.1	-1.5	1.0	0.6	0.8	1.2	-0.0	-0.3	0.5
Arm predicted mass (left)	0.2	0.9	6.6	0.4	0.1	0.4	-1.5	0.6	1.5	0.1	-2.6	0.6	0.6	-1.0	-0.3	-0.7	0.0	-0.1
Bipolar Disorder (2018)	0.1	0.1	0.8	0.1	0.0	-0.2	0.2	-0.3	0.9	0.0	0.6	-0.5	-0.1	0.0	0.3	-0.0	0.2	-0.1
Crohns Disease (2012)	0.1	0.2	0.8	-0.2	-0.0	-0.2	-0.1	-0.4	-0.6	0.3	0.9	-0.6	-0.3	0.2	-0.3	-0.9	-0.4	-0.1
Primary Biliary Cirrhosis	0.1	0.1	0.5	0.5	0.1	0.2	-0.2	0.1	0.0	0.4	-0.7	-0.2	0.3	-0.7	0.7	0.5	0.2	0.2
Tanning	0.1	0.6	2.7	0.3	0.9	0.7	0.8	0.9	0.1	0.8	-1.6	1.0	0.7	0.9	1.0	0.3	0.3	0.8
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.9	-0.6	-0.0	-0.5	0.2	-0.1	0.2	0.2	-0.3	-0.2	-0.3	1.0	0.6	-0.3	0.3	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.6	-0.2	-0.1	-0.0	0.1	0.6	0.0	-0.1	-0.4	-0.2	0.0	0.0	0.6	0.8	-0.6	-0.1
Mouth/teeth dental problems	0.1	0.2	1.3	0.3	-0.1	0.2	0.5	-0.1	0.0	0.2	0.4	0.8	-0.0	-0.1	0.5	1.2	0.6	0.0
Medication: Seretide 50 evohaler	0.1	0.1	0.5	-0.0	0.3	0.2	0.2	-0.0	-0.1	0.1	0.7	0.7	0.1	0.4	0.1	0.2	-0.3	0.2
Leg pain on walking	0.1	0.1	0.3	-0.4	-0.3	-0.3	0.6	-0.1	-0.1	-0.0	0.2	-0.1	-0.3	0.3	-0.2	0.0	-0.5	-0.1
Average weekly red wine intake	0.1	0.2	0.7	-0.7	0.0	-0.3	0.6	-0.1	0.4	0.2	-0.6	0.6	-0.5	0.2	0.5	0.9	-0.4	-0.0
Ever had prostate specific antigen (PSA) test	0.1	0.2	1.6	-0.2	-0.3	-0.0	0.6	-0.0	0.1	-0.2	1.3	0.2	-0.1	-0.2	-0.4	0.5	0.2	0.1

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TOM1L2

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Trait associations