[Hub]/) : Traits : Systolic Blood Pressure :

chr6:42,052,577-44,034,691

Best TWAS P=1.17e-17 · Best GWAS P=1.75e-18 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 NTR Blood ZNF318 0.04 0.03 lasso 8 0.02 1.3e-08 8.2 8.2 3.1e-16 0.83 0.52 0.48 FALSE
2 ROSMAP Brain Pre-frontal Cortex GLTSCR1L 0.08 0.06 bslmm 381 0.05 1.4e-07 4.7 6.5 9.2e-11 0.24 1.00 0.00 FALSE
3 ROSMAP Brain Pre-frontal Cortex PPP2R5D 0.05 0.00 bslmm 366 0.03 1.1e-04 8.8 -7.6 2.9e-14 -0.66 0.01 0.94 FALSE
4 YFS Blood MEA1 0.01 0.00 blup 351 0.01 4.4e-03 -3.2 -7.0 2.1e-12 -0.33 0.12 0.02 TRUE
5 YFS Blood ZNF318 0.10 0.08 lasso 5 0.10 5.6e-31 8.5 -6.8 1.1e-11 -0.86 0.02 0.98 FALSE
6 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CRIP3 0.08 0.08 blup 34 0.07 1.0e-04 7.7 7.4 1.4e-13 0.67 0.11 0.78 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma ZNF318 0.05 0.06 lasso 3 0.05 1.1e-06 8.7 -8.6 1.2e-17 -0.99 0.00 1.00 TRUE
8 The Cancer Genome Atlas Soft Tissue Sarcoma ZNF318 0.04 0.02 blup 48 0.04 2.2e-03 7.8 7.6 3.1e-14 0.69 0.04 0.15 FALSE