Best TWAS P=1.17e-17 · Best GWAS P=1.75e-18 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | ZNF318 | 0.04 | 0.03 | lasso | 8 | 0.02 | 1.3e-08 | 8.2 | 8.2 | 3.1e-16 | 0.83 | 0.52 | 0.48 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | GLTSCR1L | 0.08 | 0.06 | bslmm | 381 | 0.05 | 1.4e-07 | 4.7 | 6.5 | 9.2e-11 | 0.24 | 1.00 | 0.00 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | PPP2R5D | 0.05 | 0.00 | bslmm | 366 | 0.03 | 1.1e-04 | 8.8 | -7.6 | 2.9e-14 | -0.66 | 0.01 | 0.94 | FALSE |
| 4 | YFS | Blood | MEA1 | 0.01 | 0.00 | blup | 351 | 0.01 | 4.4e-03 | -3.2 | -7.0 | 2.1e-12 | -0.33 | 0.12 | 0.02 | TRUE |
| 5 | YFS | Blood | ZNF318 | 0.10 | 0.08 | lasso | 5 | 0.10 | 5.6e-31 | 8.5 | -6.8 | 1.1e-11 | -0.86 | 0.02 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CRIP3 | 0.08 | 0.08 | blup | 34 | 0.07 | 1.0e-04 | 7.7 | 7.4 | 1.4e-13 | 0.67 | 0.11 | 0.78 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF318 | 0.05 | 0.06 | lasso | 3 | 0.05 | 1.1e-06 | 8.7 | -8.6 | 1.2e-17 | -0.99 | 0.00 | 1.00 | TRUE |
| 8 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZNF318 | 0.04 | 0.02 | blup | 48 | 0.04 | 2.2e-03 | 7.8 | 7.6 | 3.1e-14 | 0.69 | 0.04 | 0.15 | FALSE |