[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr6:34,747,603-36,581,149

Best TWAS P=1.14e-10 · Best GWAS P=2.85e-11 conditioned to 0.00763

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial RPL10A 0.11 0.08 lasso 2 0.09 1.5e-07 4.6 5.2 2.2e-07 0.42 0.46 0.54 FALSE
2 GTEx Skin Not Sun Exposed Suprapubic TEAD3 0.15 0.06 lasso 5 0.08 2.5e-05 4.2 5.2 2.0e-07 0.68 0.04 0.95 FALSE
3 GTEx Skin Sun Exposed Lower leg SRPK1 0.14 0.00 enet 27 0.02 1.2e-02 1.6 -6.0 2.5e-09 -0.18 0.23 0.09 TRUE
4 GTEx Thyroid RPL10A 0.16 0.09 lasso 11 0.07 8.9e-06 5.2 5.2 2.5e-07 0.35 0.58 0.35 FALSE
5 ROSMAP Brain Pre-frontal Cortex TEAD3 0.07 0.03 bslmm 421 0.04 5.6e-06 -2.8 6.4 1.1e-10 0.28 0.13 0.84 TRUE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TCP11 0.03 0.02 blup 49 0.02 1.7e-03 5.2 5.7 9.1e-09 0.68 0.03 0.93 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma TCP11 0.05 0.04 blup 49 0.06 1.3e-07 5.0 5.8 6.0e-09 0.62 0.19 0.80 FALSE
8 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TCP11 0.03 0.03 blup 49 0.03 3.5e-04 5.0 5.9 4.2e-09 0.62 0.15 0.62 FALSE
9 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TCP11 0.05 0.07 lasso 2 0.07 1.9e-05 5.2 5.2 1.7e-07 0.54 0.17 0.68 TRUE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma TCP11 0.08 0.11 lasso 2 0.11 3.4e-05 5.2 5.1 2.8e-07 0.53 0.17 0.38 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma TCP11 0.03 0.02 blup 49 0.02 1.6e-03 5.2 6.4 2.1e-10 0.65 0.03 0.65 TRUE