[Hub]/) : Traits : Systolic Blood Pressure :

chr6:95,831,017-97,979,053

Best TWAS P=3.54e-16 · Best GWAS P=1.82e-16 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum FHL5 0.11 0.00 lasso 4 -0.01 8.3e-01 7.85 -6.0 1.6e-09 -0.59 0.05 0.26 FALSE
2 GTEx Artery Tibial UFL1 0.08 0.05 lasso 4 0.04 7.9e-04 8.12 8.1 6.5e-16 0.96 0.03 0.96 FALSE
3 GTEx Artery Tibial FHL5 0.08 0.00 enet 48 0.02 7.2e-03 8.12 -6.2 5.9e-10 -0.51 0.03 0.85 FALSE
4 GTEx Breast Mammary Tissue (Male) GPR63 0.25 -0.01 enet 37 -0.01 7.9e-01 7.96 5.1 2.8e-07 0.62 0.04 0.32 FALSE
5 GTEx Nerve Tibial UFL1 0.09 0.11 lasso 8 0.08 2.8e-06 8.15 8.2 3.5e-16 0.99 0.02 0.97 TRUE
6 GTEx Pancreas UFL1 0.08 0.11 enet 7 0.09 1.1e-04 7.42 7.7 1.9e-14 0.95 0.04 0.91 FALSE
7 GTEx Testis FHL5 0.11 0.11 lasso 5 0.10 3.5e-05 4.34 -5.1 2.9e-07 -0.61 0.09 0.73 FALSE
8 GTEx Thyroid UFL1 0.06 0.00 lasso 2 0.00 6.6e-01 8.20 7.2 4.8e-13 0.92 0.03 0.84 FALSE
9 NTR Blood KIAA0776 0.02 0.02 lasso 1 0.02 1.1e-07 6.02 6.0 1.8e-09 0.68 0.98 0.02 FALSE
10 ROSMAP Brain Pre-frontal Cortex FHL5 0.04 0.03 bslmm 444 0.02 2.9e-03 7.42 -7.7 1.0e-14 -0.87 0.05 0.93 FALSE
11 ROSMAP Brain Pre-frontal Cortex FUT9 0.04 0.00 bslmm 486 0.01 1.1e-02 0.15 5.8 7.1e-09 0.53 0.07 0.38 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma FHL5 0.03 0.02 blup 55 0.01 7.1e-03 8.12 -7.8 8.3e-15 -0.90 0.01 0.88 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FHL5 0.03 0.03 enet 3 0.02 1.9e-03 8.10 -7.5 6.6e-14 -0.85 0.01 0.74 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma FHL5 0.07 0.00 blup 55 0.01 4.8e-02 8.21 -6.7 1.8e-11 -0.74 0.01 0.59 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma KIAA0776 0.05 0.07 lasso 2 0.06 1.8e-06 8.15 8.1 3.9e-16 0.99 0.01 0.99 FALSE