[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr6:116,950,734-119,578,310

Best TWAS P=5.31e-21 · Best GWAS P=1.15e-11 conditioned to 0.514

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GOPC 0.12 0.11 lasso 7 0.09 2.2e-11 5.3 6.0 2.4e-09 0.63 0.93 0.07 FALSE
2 GTEx Artery Aorta GOPC 0.11 0.09 enet 13 0.12 4.7e-07 6.0 -6.4 1.2e-10 -0.81 0.03 0.97 FALSE
3 GTEx Artery Tibial GOPC 0.11 0.08 lasso 4 0.09 9.0e-08 5.2 -6.6 4.0e-11 -0.81 0.06 0.94 FALSE
4 GTEx Artery Tibial PLN 0.09 0.05 lasso 2 0.03 2.5e-03 5.7 5.8 6.4e-09 0.01 0.02 0.97 TRUE
5 GTEx Breast Mammary Tissue DCBLD1 0.10 0.02 lasso 4 0.03 1.1e-02 6.2 -6.6 3.0e-11 -0.82 0.02 0.85 FALSE
6 GTEx Breast Mammary Tissue (Male) GOPC 0.05 0.03 enet 7 0.05 2.2e-02 2.7 -5.7 1.2e-08 -0.77 0.02 0.68 FALSE
7 GTEx Muscle Skeletal NUS1 0.09 0.04 enet 14 0.08 1.1e-08 -5.2 -6.8 1.2e-11 -0.57 0.86 0.08 FALSE
8 GTEx Nerve Tibial GOPC 0.12 0.06 enet 17 0.06 3.7e-05 6.3 -6.5 6.0e-11 -0.91 0.02 0.98 FALSE
9 GTEx Thyroid GOPC 0.11 0.02 enet 23 0.02 1.6e-02 6.8 -9.4 5.3e-21 -0.66 0.01 0.98 TRUE
10 GTEx Thyroid DCBLD1 0.27 0.22 enet 14 0.24 1.3e-18 -4.2 -5.4 7.5e-08 -0.45 1.00 0.00 FALSE
11 GTEx Whole Blood DCBLD1 0.16 0.09 lasso 7 0.09 7.7e-09 -3.7 6.0 1.5e-09 0.56 0.87 0.13 FALSE
12 NTR Blood DCBLD1 0.02 0.02 lasso 4 0.02 1.1e-07 -5.3 5.3 1.0e-07 0.41 0.94 0.06 FALSE
13 ROSMAP Brain Pre-frontal Cortex GOPC 0.13 0.16 enet 21 0.16 1.5e-19 4.7 6.6 3.7e-11 0.78 0.43 0.57 FALSE
14 YFS Blood DCBLD1 0.13 0.13 enet 26 0.14 2.2e-44 -5.3 5.2 1.8e-07 0.41 0.95 0.05 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma GOPC 0.02 0.02 lasso 1 0.02 2.1e-04 6.0 -6.0 2.0e-09 -0.83 0.13 0.78 FALSE
16 The Cancer Genome Atlas Breast Invasive Carcinoma ROS1 0.03 0.03 enet 9 0.03 3.0e-06 -5.2 5.5 4.7e-08 0.31 0.02 0.98 FALSE