Best TWAS P=2.09e-08 · Best GWAS P=2.09e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | CCT6A | 0.06 | 0.03 | lasso | 2 | 0.02 | 1.1e-02 | 5.3 | 5.3 | 1.4e-07 | 0.74 | 0.01 | 0.95 | FALSE |
2 | METSIM | Adipose | CCT6A | 0.03 | 0.04 | lasso | 1 | 0.03 | 2.0e-05 | 5.6 | 5.6 | 2.1e-08 | 1.00 | 0.00 | 1.00 | TRUE |
3 | YFS | Blood | CCT6A | 0.03 | 0.02 | lasso | 4 | 0.02 | 5.5e-06 | 5.6 | 5.3 | 1.3e-07 | 0.98 | 0.00 | 1.00 | FALSE |
4 | YFS | Blood | GBAS | 0.02 | 0.01 | lasso | 6 | 0.01 | 2.0e-03 | 5.6 | 5.2 | 1.5e-07 | 0.98 | 0.00 | 0.99 | FALSE |