[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr8:164,984-2,381,004

Best TWAS P=1.2e-10 · Best GWAS P=3.4e-07 conditioned to 0.111

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP5-855D21.2 0.16 0.13 enet 12 0.15 1.4e-12 -4.5 -5.6 2.4e-08 -0.04 0.02 0.93 FALSE
2 GTEx Brain Cerebellar Hemisphere CTD-2336O2.1 0.55 0.09 enet 6 0.00 2.8e-01 -5.1 5.1 3.0e-07 -0.96 0.02 0.85 FALSE
3 GTEx Cells Transformed fibroblasts ZNF596 0.27 0.13 lasso 5 0.13 8.1e-10 -4.6 5.2 1.9e-07 0.02 0.01 0.97 FALSE
4 GTEx Esophagus Mucosa CLN8 0.17 0.00 lasso 4 0.00 3.3e-01 -4.9 5.8 6.9e-09 -0.82 0.03 0.59 TRUE
5 GTEx Esophagus Mucosa CTD-2336O2.1 0.26 0.11 enet 27 0.12 1.5e-08 -5.0 5.3 1.1e-07 -0.82 0.01 0.98 FALSE
6 GTEx Lung CLN8 0.17 0.07 lasso 4 0.07 3.8e-06 -5.1 5.3 1.4e-07 -0.94 0.01 0.99 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic CTD-2336O2.1 0.46 0.18 lasso 10 0.15 2.2e-08 -5.0 5.4 5.4e-08 -0.93 0.01 0.98 FALSE
8 GTEx Skin Sun Exposed Lower leg CTD-2336O2.1 0.22 0.14 lasso 4 0.15 3.1e-12 -4.9 5.3 1.1e-07 -0.95 0.01 0.98 FALSE
9 GTEx Whole Blood ERICH1 0.26 0.08 enet 27 0.19 6.2e-17 3.3 5.7 1.0e-08 0.02 0.01 0.98 FALSE
10 METSIM Adipose CLN8 0.10 0.05 enet 18 0.08 1.3e-11 -5.0 5.2 2.2e-07 -0.86 0.01 0.99 FALSE
11 NTR Blood ERICH1 0.27 0.18 enet 54 0.31 5.5e-101 4.2 6.4 1.2e-10 0.05 0.10 0.79 TRUE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RPL23AP53 0.12 0.06 enet 9 0.07 2.4e-05 -4.6 -5.2 2.4e-07 -0.02 0.00 0.96 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma RPL23AP53 0.52 0.24 lasso 6 0.38 1.2e-39 -4.6 -5.5 3.0e-08 -0.04 0.00 0.98 TRUE