Hub : Genes

ERICH1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1610 0.0340 7.0e-10 0.067 0.113 0.114 0.114 0.109 1.6e-08 1.4e-13 1.1e-13 1.1e-13 3.9e-13
2 GTEx Brain Cerebellar Hemisphere 0.5130 0.1260 7.7e-04 0.138 NA 0.156 NA 0.120 2.2e-04 NA 8.2e-05 NA 5.6e-04
3 GTEx Brain Cerebellum 0.3250 0.1160 6.0e-03 0.208 NA 0.081 NA 0.199 8.6e-07 NA 2.2e-03 NA 1.6e-06
4 GTEx Whole Blood 0.2580 0.0480 1.0e-08 0.078 NA 0.186 NA 0.173 1.1e-07 NA 6.2e-17 NA 9.2e-16
5 NTR Blood 0.2698 0.0295 0.0e+00 0.179 0.280 0.306 0.293 0.291 2.2e-55 6.7e-91 5.5e-101 1.0e-95 4.6e-95
6 ROSMAP Brain Pre-frontal Cortex 0.2573 0.0462 2.5e-14 0.128 0.136 0.156 0.133 0.130 3.9e-16 3.9e-17 1.4e-19 1.1e-16 2.1e-16
7 YFS Blood 0.6069 0.0291 0.0e+00 0.353 0.582 0.596 0.594 0.581 1.1e-121 4.1e-241 6.6e-251 1.8e-249 6.2e-241
8 TCGA Bladder Urothelial Carcinoma 0.1780 0.0500 4.0e-07 0.093 0.085 0.087 NA 0.075 2.7e-08 1.2e-07 7.6e-08 NA 6.1e-07
9 TCGA Breast Invasive Carcinoma 0.0458 0.0184 5.0e-05 0.014 0.022 0.017 NA 0.015 5.5e-04 1.7e-05 1.7e-04 NA 3.0e-04
10 TCGA Kidney Renal Clear Cell Carcinoma 0.0529 0.0353 6.5e-03 0.019 0.011 0.006 NA 0.013 2.9e-03 1.7e-02 7.0e-02 NA 1.0e-02
11 TCGA Brain Lower Grade Glioma 0.0734 0.0309 4.1e-05 0.026 0.038 0.030 NA 0.032 5.1e-04 3.6e-05 2.3e-04 NA 1.3e-04
12 TCGA Ovarian Serous Cystadenocarcinoma 0.2260 0.0930 1.2e-03 0.012 0.033 0.028 NA 0.019 4.9e-02 2.5e-03 5.1e-03 NA 1.8e-02
13 TCGA Stomach Adenocarcinoma 0.0920 0.0470 1.3e-03 0.010 0.012 0.012 NA 0.001 5.5e-02 4.2e-02 4.0e-02 NA 2.8e-01
14 TCGA Thyroid Carcinoma 0.0790 0.0400 2.6e-04 0.027 0.035 0.052 NA 0.045 1.2e-03 2.2e-04 8.3e-06 NA 2.9e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.6 0.9 4.6 -0.7 -0.6 0.0 0.8 0.1 -1.4 0.9 -1.7 -0.9 -0.3 0.4 -2.1 -0.2 -0.5
Bipolar Disorder or Schizophrenia 0.9 2.2 5.6 -1.5 -1.7 0.3 2.3 0.6 -1.5 1.8 -2.4 -1.9 -0.8 -0.5 -1.9 0.0 -0.2
Depressed Affect (Nagel 2018) 0.4 0.8 6.5 -0.9 -0.5 2.5 -0.7 -0.5 -0.0 -0.7 -0.1 1.2 -0.0 0.4 1.0 0.4 -0.4
Depression (Nagel 2018) 0.3 0.5 2.0 -0.6 -0.2 1.4 1.0 0.6 -0.6 0.2 -0.9 -0.1 -0.2 0.7 0.7 1.1 -0.3
Intelligence (Savage-Jansen 2018) 0.4 1.1 4.0 1.4 0.5 -2.0 0.2 -0.2 1.7 -0.1 1.6 0.9 1.3 0.3 -0.7 -0.5 0.1
Neuroticism (Nagel 2018) 0.5 1.3 4.8 -0.7 0.1 2.2 0.1 0.8 0.3 -1.3 -0.0 2.0 -1.0 -0.1 1.3 1.5 -1.3
Schizophrenia (2018) 0.8 1.6 6.3 -1.4 -1.7 0.4 2.5 0.7 -0.8 1.6 -1.6 -1.7 -0.7 -1.0 -0.8 -0.4 0.2
Schizophrenia vs Biploar Disorder 0.5 0.6 3.0 -0.7 0.0 0.3 0.2 -0.9 0.7 0.7 0.3 -0.7 0.5 -0.5 0.9 -1.0 1.7
Worry (Nagel 2018) 1.1 2.2 6.0 -1.2 0.5 1.9 -0.0 1.4 0.2 -2.2 0.8 2.5 -1.6 -0.0 2.0 2.1 -1.2
Alzheimer’s Disease (in mother) 0.9 1.1 3.6 0.5 0.8 -0.7 -1.9 -1.8 0.3 -0.2 0.4 0.0 1.6 1.3 0.9 -0.6 0.9
Alzheimer’s Disease (in father) 2.6 2.8 11.6 0.4 -1.4 0.5 -1.3 0.7 -1.2 -2.7 1.8 2.6 -1.5 -1.2 0.5 0.2 -3.4
Alzheimer’s Disease (including proxy) 0.8 1.1 4.1 0.7 -0.2 -0.9 -2.0 -1.4 -0.2 -1.2 1.0 1.2 1.0 1.4 1.3 -0.1 -0.2
Crohns Disease (2017) 0.4 0.9 2.7 0.6 1.0 -1.6 0.6 0.5 0.7 1.4 -0.5 -1.6 0.2 -1.1 -0.3 -0.6 0.4
Irritable Bowel Disease (IBD) 0.8 2.0 7.8 1.6 1.8 -2.8 0.8 0.2 1.9 1.7 0.6 -1.0 1.6 -0.6 -0.2 -0.7 1.6
Ulcerative Colitis (UC) 0.6 1.2 2.9 1.1 1.7 -1.7 0.5 -0.2 1.2 1.4 0.7 -1.0 1.4 -0.4 -0.3 -0.8 1.4
Major Depression (MDD) 1.6 1.9 5.7 0.3 -1.1 -0.9 1.3 -0.5 -1.0 2.3 -2.1 -2.2 0.5 -0.4 -2.4 -0.6 0.8
Reaction Time 1.0 1.9 6.4 -1.3 -1.3 1.8 -1.2 0.4 -2.5 -1.6 0.9 1.4 -1.1 0.2 0.6 -0.2 -2.2
Verbal and Numeric Reasoning (VNR) 0.8 1.8 7.2 2.7 0.9 -2.1 0.3 0.0 2.1 -0.4 1.8 1.0 1.1 -0.6 -0.6 -1.3 -0.9
Breast Cancer 0.6 1.4 5.6 1.3 -0.9 -1.7 0.9 -0.4 0.5 1.3 -2.4 -1.3 0.9 -0.1 -1.6 -0.7 0.4
Ovarian Cancer 0.8 1.0 4.0 -0.7 -2.0 1.7 -1.0 -0.2 -1.1 0.5 -0.6 -0.9 -1.0 -0.7 -0.1 -1.4 -0.6
Prostate Cancer 1.1 1.5 3.6 1.3 0.0 -0.9 -1.5 -0.8 1.1 -1.8 1.7 1.4 1.5 1.2 1.9 -0.0 -0.5
Age at First Birth 0.3 0.5 2.6 -0.3 0.9 0.2 0.0 -0.5 0.4 -0.4 0.0 1.1 0.7 0.1 1.6 0.8 0.5
Bipolar Disorder (2011) 0.8 0.8 3.5 -0.5 -0.0 0.2 1.2 0.9 -0.7 1.1 -1.9 -1.6 -0.8 -0.3 -0.5 -0.0 0.4
Body Mass Index (BMI) (2010) 0.6 0.9 4.0 -0.3 0.5 0.3 -0.7 -0.2 -1.0 -1.7 0.9 0.7 -0.4 -0.8 1.0 0.6 -2.0
Coronary Artery Disease (CAD) 0.4 0.5 1.3 1.1 0.7 -0.6 -0.8 -0.4 0.5 -0.2 0.7 0.5 0.8 1.1 -0.1 0.3 0.7
Crohns Disease (2012) 1.1 1.8 4.8 1.7 1.0 -2.0 0.5 -0.1 1.8 2.2 -0.9 -1.2 1.6 0.4 -0.3 0.2 1.9
Mean Putamen Volume 0.3 0.3 1.2 0.5 0.7 -0.1 -0.6 -0.0 -0.3 -0.3 0.2 0.7 -0.1 0.7 -1.0 1.1 -0.2
Fasting Glucose 0.4 0.4 1.1 -0.5 -0.8 -0.1 0.7 0.0 -0.4 1.1 -0.7 -0.8 -0.8 -0.6 -0.5 -0.3 0.8
HbA1C 0.8 0.9 4.4 0.6 1.4 -0.4 2.1 1.1 0.9 0.4 -0.7 0.1 -1.0 -0.6 0.3 0.1 1.1
HDL Cholesterol 1.5 2.5 8.5 1.1 -0.6 -0.9 1.8 2.9 0.3 0.7 0.0 0.1 -2.1 -2.9 -2.1 -0.0 -1.8
LDL Cholesterol 0.3 0.5 2.7 0.4 -0.2 -0.1 1.6 0.6 0.5 1.4 -1.1 -0.2 0.1 -0.6 -0.3 -0.1 0.5
Lupus 0.7 1.1 3.0 0.2 -1.2 0.4 1.5 1.5 -0.1 -0.2 1.0 0.8 -1.2 -1.7 0.1 -1.2 -1.1
Neuroticism (2016) 1.0 1.4 5.9 -1.6 0.8 1.0 0.9 1.5 0.2 -0.5 -0.5 0.1 -2.4 -2.0 0.3 0.3 -1.2
Primary Biliary Cirrhosis 0.3 0.5 2.5 0.2 -0.5 0.0 0.2 0.2 -0.5 1.0 -0.4 -0.7 -0.5 -1.6 -0.7 -0.8 -0.6
Rheumatoid Arthritis 0.4 0.6 2.7 0.4 -0.7 -0.5 -0.9 -1.6 -0.3 -1.4 0.7 -0.2 0.5 0.8 0.6 -0.6 -0.1
Schizophrenia (2014) 0.6 1.4 3.3 -1.4 -1.8 0.6 1.8 0.1 -0.8 1.3 -1.2 -1.8 -0.7 -0.9 -0.7 -1.1 0.3
Triglycerides 0.3 0.6 1.2 -1.1 0.6 0.9 -0.8 0.0 -0.7 -1.1 0.7 0.8 -0.5 -0.1 1.0 0.3 -0.6
Type 2 Diabetes (T2D) (2012) 0.5 0.5 1.3 0.8 -0.8 -0.1 -0.3 -0.9 -0.4 1.1 0.6 -0.1 1.1 0.5 -0.1 -0.8 1.1
Ulcerative Colitis 1.0 1.4 3.6 1.7 1.7 -1.9 0.7 0.5 1.9 1.2 0.9 0.3 1.4 0.0 -0.3 0.8 1.2
Blood Eosinophil Count 0.1 0.6 1.3 -0.7 -1.1 -0.1 -0.7 -1.1 -1.1 0.2 0.5 -0.5 1.0 0.9 -0.0 -0.7 0.9
Blood Platelet Count 0.3 3.3 10.1 3.1 1.9 -2.0 0.8 1.7 2.3 -0.2 0.2 2.5 0.9 -0.1 1.4 3.2 -0.2
Blood Red Count 0.3 3.2 14.0 -0.9 -1.1 2.1 0.8 1.1 -1.4 -0.6 -1.5 -1.4 -3.7 -3.2 -1.0 -1.1 -2.0
Blood White Count 0.2 1.5 6.2 0.4 -0.7 -0.2 -0.7 -2.5 -0.6 1.2 0.2 -1.4 1.5 1.3 0.1 -0.6 2.4
Heel T-Score 0.2 1.3 4.2 -2.0 -1.1 1.4 0.3 0.5 -1.0 -0.1 -0.2 -0.1 -1.6 -1.5 -1.4 -1.4 -0.5
BMI 0.5 3.1 7.6 0.1 -1.5 -0.4 -0.5 -2.6 -1.0 2.1 -0.8 -2.5 1.8 1.0 -2.8 -2.6 1.7
Height 0.2 3.1 13.0 -0.8 -1.8 0.6 0.7 2.2 -1.6 -2.1 -0.3 1.0 -2.9 -1.8 -0.4 1.1 -3.6
Waist Hip Ratio (WHR) 0.4 2.0 5.8 -1.5 0.2 1.5 -0.5 0.8 -1.0 -1.8 1.5 2.3 -0.9 -0.5 2.4 0.7 -1.7
Systolic Blood Pressure 1.9 9.6 41.5 0.9 -0.1 -1.5 5.7 6.4 1.9 1.6 -2.2 0.1 -4.2 -4.4 -1.0 2.2 -1.8
Smoking Status 0.3 0.7 2.6 -0.3 -0.9 -0.0 -0.5 -1.5 -1.6 0.4 0.3 -0.6 0.7 1.0 -0.1 -1.1 0.8
Allergy or Eczema 0.4 1.1 3.7 -1.4 0.2 1.1 -1.1 -0.8 -1.9 -0.7 -0.3 -0.5 -1.5 -0.6 0.7 -0.9 -1.2
Cardiovascular Disease 0.2 0.6 2.2 -0.1 -0.3 -1.0 0.6 1.1 0.6 -0.1 0.4 -0.1 -0.7 -0.5 1.4 1.5 -0.1
Hypothyroidism (self reported) 0.2 0.4 1.2 0.1 0.8 0.2 -0.7 -1.1 -0.1 -0.6 0.6 0.2 0.7 1.0 0.7 0.3 0.9
Respiratory disease 0.6 1.4 4.8 -0.5 0.4 1.4 -1.5 -1.3 -0.7 -1.4 0.8 0.6 0.7 2.1 2.2 0.4 0.5
Type 2 Diabetes (T2D) (2018) 0.4 0.7 1.9 -0.5 0.4 -0.3 -0.5 -1.2 0.1 0.6 -0.4 -1.1 1.3 1.4 0.8 0.4 1.3
Lung FEV1/FVC ratio 0.5 2.8 13.1 0.9 -1.4 -1.7 1.6 0.5 0.5 2.2 -0.9 -1.7 -0.1 -1.3 -3.6 -2.6 -0.4
Lung FVC 0.5 2.6 9.5 -0.1 1.4 -1.0 -1.4 -0.2 1.0 -2.2 1.3 1.9 1.2 2.4 3.1 1.9 0.3
Neuroticism 0.5 1.1 3.1 -0.4 0.6 1.3 1.4 1.7 1.2 -0.5 -0.1 1.7 -1.2 -0.6 0.5 1.2 -0.8
Chronotype (morning person) 0.8 1.8 8.7 0.6 0.6 -0.1 -0.3 1.3 1.2 -1.4 0.3 1.2 -1.6 -2.4 0.1 -0.3 -2.9
Hair Pigment 0.1 1.8 6.8 -0.5 -1.3 1.4 -1.9 -1.9 -2.6 -1.0 -0.4 0.6 1.1 1.6 0.0 1.1 -0.6
Tanning 0.1 0.8 2.5 -0.7 -0.4 -0.4 1.5 0.2 0.7 1.5 -1.0 -0.8 0.2 -0.8 -1.6 -1.0 0.5
Hand grip strength (left) 0.2 0.5 2.3 0.7 -0.5 -0.8 1.5 0.7 0.4 0.8 -0.8 -0.6 -0.4 -0.8 -0.2 0.1 0.4
Number of treatments/medications taken 0.6 1.0 5.3 -0.7 1.4 -0.2 -0.8 0.2 0.4 -0.3 0.3 0.5 0.4 0.9 2.3 1.9 0.5
Average weekly spirits intake 1.4 1.8 5.8 -0.1 -0.6 -0.8 2.0 0.3 -0.2 2.4 -1.4 -2.4 0.3 -0.4 -2.2 -0.8 0.7
Sensitivity / hurt feelings 0.9 1.6 4.5 -0.2 0.0 1.0 2.0 2.1 0.1 -0.7 -0.9 1.2 -1.4 -1.3 -0.0 1.3 -2.1
Frequency of depressed mood in last 2 weeks 0.2 0.3 1.2 -0.0 -0.9 1.1 0.5 0.6 -0.0 0.1 0.5 0.5 0.3 0.7 0.6 0.5 0.3
Hearing difficulty/problems: Yes 0.4 0.6 3.0 -1.7 -0.6 1.2 0.6 0.5 -0.7 -0.3 -0.3 0.0 -0.6 0.6 1.1 0.1 0.2
Relative age of first facial hair 0.6 1.2 4.7 0.6 -0.7 -1.3 0.9 1.6 0.5 -0.0 -1.0 -0.0 -0.8 -2.2 -0.6 1.1 -1.6
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 1.6 -0.6 0.6 0.0 0.6 0.4 -1.0 0.0 -1.2 -1.0 -1.0 -0.6 -0.4 0.8 -0.6
Ever used hormone-replacement therapy (HRT) 0.8 1.0 4.9 0.1 -0.0 0.0 -1.2 -0.0 -0.6 -1.3 2.2 1.5 0.3 0.6 1.4 1.0 -0.4
Ever had hysterectomy (womb removed) 0.2 0.3 1.1 0.2 -0.2 -1.1 -0.4 0.5 -0.1 -0.0 0.3 0.8 -0.2 0.3 0.5 0.7 0.7
Systolic blood pressure, automated reading 0.9 2.5 7.2 -0.6 -1.4 0.5 2.3 2.5 -1.1 0.4 -1.1 -0.4 -2.5 -2.7 -1.0 0.7 -1.7
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 1.3 0.3 -0.8 -0.4 -0.6 0.7 -0.4 -0.3 1.1 0.7 -0.7 -0.5 -0.1 0.4 -0.7
Angina 1.1 1.5 4.0 -1.7 -1.2 1.0 -0.5 0.6 -1.6 -0.9 0.5 0.1 -1.8 -0.9 0.1 -1.7 -2.0
Medication for hormone replacement therapy 0.4 0.4 1.1 -0.4 -0.4 -1.1 0.2 0.8 -0.1 1.1 -0.2 -1.1 0.2 -0.8 0.1 -0.6 0.4
Vitamin and mineral supplements 2.8 3.8 8.8 -1.6 -2.5 1.4 1.5 0.8 -2.8 1.4 -3.0 -1.1 -2.3 -2.6 -2.2 -0.6 -1.4
Supplements: Zinc 0.8 0.8 2.9 -0.4 0.3 0.2 -0.6 -1.2 -0.1 -0.1 1.2 0.0 1.5 1.7 0.7 -0.4 1.6
Medication: Co-codamol 3.0 3.4 12.9 -2.1 -3.6 2.5 -0.7 -1.5 -3.1 0.9 -2.2 -1.6 0.2 1.1 -1.3 -1.2 0.2
Medication: Metformin 0.1 0.2 0.7 -0.4 -0.0 -0.5 -0.1 0.3 -0.4 -0.0 -0.3 -0.5 -0.4 0.5 0.9 0.5 0.4
Diabetes (father) 0.8 1.0 7.0 0.6 -2.6 -1.0 -0.8 -0.7 0.2 -0.6 1.5 0.4 0.3 0.2 -0.0 -1.3 -0.4
Diabetes (mother) 0.5 0.6 1.9 -0.4 -1.4 0.4 -1.1 -0.7 -1.3 -0.3 -0.2 -1.1 -0.7 -0.2 -0.1 -0.9 -0.6
Severe depression (siblings) 1.0 1.1 5.0 1.0 0.9 -1.4 1.1 0.7 2.2 0.5 0.6 0.1 0.8 -0.0 0.7 1.0 1.3
Pack years adult smoking proportion 0.4 0.5 2.2 0.1 -1.5 -1.1 0.7 1.1 0.8 0.1 0.4 0.6 -0.3 -0.6 0.9 -0.4 0.1
Impedance of leg (right) 0.3 1.3 5.5 -0.9 -0.2 0.7 1.4 1.6 0.1 0.5 -1.3 -0.7 -1.9 -2.4 0.6 -0.0 -0.9
Leg fat-free mass (left) 0.2 1.0 6.5 0.2 -1.1 -0.9 0.2 -0.5 -0.9 1.1 -0.2 -0.9 0.6 0.9 -2.5 -0.9 0.6
Trunk fat percentage 0.4 1.7 7.8 -0.2 -1.7 -0.5 0.7 -1.0 -1.2 1.6 -0.8 -1.9 0.3 -0.1 -2.8 -1.7 0.8
Hand grip strength (right) 0.3 0.8 2.7 0.8 -0.3 -1.4 1.6 0.6 0.6 0.9 -1.2 -0.6 -0.7 -1.1 -0.6 -0.0 0.0
Townsend deprivation index at recruitment 0.4 0.6 1.9 -0.7 -1.4 -0.2 0.2 0.2 -0.4 0.9 0.1 -0.6 1.1 1.1 -0.1 -0.7 1.1
Current tobacco smoking 0.5 0.9 4.8 -0.6 -2.2 0.5 0.8 1.0 -0.9 0.7 -0.8 -0.2 -1.3 -0.8 -0.4 -0.3 -0.7
Average weekly fortified wine intake 1.2 1.4 6.0 0.6 0.4 0.3 -2.5 -0.9 0.3 -1.8 1.8 1.6 0.7 0.8 0.7 0.7 -0.7
Maternal smoking around birth 0.3 0.5 1.9 -0.6 -1.0 0.6 -1.4 -0.8 -0.7 -0.0 0.2 0.2 0.5 1.2 0.4 0.3 0.1
Fed-up feelings 0.7 1.3 3.5 0.0 -0.6 1.8 -0.9 -0.7 0.5 -0.4 1.3 1.6 1.2 1.9 1.0 -1.4 0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.6 2.5 0.6 0.2 -0.2 0.8 0.8 0.6 0.2 0.2 0.4 0.8 1.6 1.1 0.8 0.8
Relative age voice broke 1.1 1.6 7.8 1.3 0.1 -2.4 0.3 1.2 1.0 -0.5 0.5 1.5 -0.1 -0.4 1.0 2.8 -0.8
Taking other prescription medications 0.6 0.9 3.1 -0.8 1.6 -0.3 0.7 1.0 0.2 0.2 -0.5 -0.0 -0.6 0.5 1.7 1.8 0.8
Age when periods started (menarche) 1.0 2.4 8.0 -0.2 0.3 0.4 2.8 0.9 -0.3 2.5 -2.8 -1.3 0.1 -1.5 -2.5 -1.0 0.1
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 0.9 0.3 -0.8 -0.8 -0.1 0.3 -0.4 -0.5 0.3 -0.4 -0.6 -0.9 -0.4 0.0 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 1.3 -0.3 0.5 -0.6 0.1 0.2 1.0 0.8 -0.2 -0.7 0.5 0.1 -1.1 -0.4 0.8
Tinnitus: Yes, but not now, but have in the past 1.3 1.4 4.2 0.3 2.1 0.3 -2.0 -1.1 -0.7 -1.6 0.9 1.4 0.4 1.5 0.9 0.8 0.9
Qualifications: CSEs or equivalent 0.4 0.6 4.0 0.6 -0.0 -0.4 0.4 1.1 0.8 -0.4 -0.5 -0.1 -0.3 0.8 0.6 2.0 -0.1
Serious illness, injury or assault to yourself 0.8 1.0 3.5 -0.3 -1.2 0.4 1.9 1.5 0.9 1.0 -0.2 0.0 -1.4 -1.3 0.5 0.2 0.6
High blood pressure 0.4 1.0 3.4 -1.0 -0.1 -0.9 1.0 1.8 0.3 -0.3 -0.1 0.0 -1.4 -1.2 0.4 1.6 -1.4
Hayfever, allergic rhinitis or eczema 0.4 0.9 2.9 -1.4 -0.2 1.2 -1.3 -1.2 -1.7 -0.8 -0.3 -0.5 -0.8 0.4 1.0 -0.6 -0.4
Multivitamins +/- minerals 3.6 4.5 13.7 2.0 2.6 -1.8 -1.1 -0.1 3.0 -1.1 3.7 1.9 2.4 2.5 2.5 0.8 1.3
Stomach or abdominal pain in last month 2.2 2.8 8.1 -1.9 -1.2 0.3 2.0 1.2 -0.7 1.1 -2.8 -1.7 -2.8 -2.1 -1.5 0.8 -0.5
Supplements: Glucosamine 0.6 0.8 2.9 0.9 1.5 -0.5 -0.9 -1.7 0.8 0.2 0.3 -0.4 1.2 0.1 -0.7 -1.0 0.1
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 3.0 -0.4 0.6 -0.2 1.2 0.8 0.6 0.6 -1.5 -0.4 -0.5 -0.3 -0.1 1.7 0.6
Medication: Atenolol 0.9 1.1 3.6 0.7 -0.0 -0.8 -0.4 1.2 -0.5 -1.2 0.7 1.6 -0.2 -0.1 1.6 1.9 -1.2
Medication: Levothyroxine sodium 0.2 0.4 2.0 0.0 1.4 -0.0 -0.0 -0.5 -0.1 -0.8 -1.0 0.2 -0.3 -0.0 0.6 0.9 -0.2
Sitting height 0.1 1.0 3.6 0.1 -0.5 -1.1 1.3 1.0 -0.1 0.6 -1.9 -0.9 -1.2 -0.8 -1.6 -0.2 -0.2
Chronic bronchitis/emphysema (father) 0.3 0.3 1.1 1.0 1.0 -0.9 0.4 0.8 0.3 0.2 -0.0 -0.4 0.3 -0.0 0.3 0.5 -0.3
High blood pressure (mother) 1.1 1.6 3.5 -1.0 -1.8 0.2 1.8 1.1 -0.6 1.6 -1.9 -1.5 -1.2 -1.0 -1.2 -1.0 0.2
Body mass index (BMI) 0.5 2.2 7.0 0.3 -1.7 -0.4 -0.4 -2.0 -1.0 1.5 0.1 -1.4 1.9 1.6 -2.6 -1.9 1.4
Impedance of leg (left) 0.3 1.4 6.4 -0.4 -0.1 -0.1 1.4 1.6 0.6 0.0 -1.2 -0.4 -2.0 -2.5 0.9 0.2 -1.2
Leg predicted mass (left) 0.2 1.0 6.4 0.3 -1.1 -1.0 0.3 -0.4 -0.8 1.1 -0.1 -0.8 0.6 0.9 -2.5 -0.9 0.6
Trunk fat mass 0.4 1.8 8.1 -0.2 -1.7 -0.7 0.4 -1.1 -1.3 1.7 -0.8 -1.8 0.6 0.4 -2.9 -1.6 1.0
Waist circumference 0.4 1.3 3.0 -0.6 -1.7 -0.4 -0.3 -1.6 -1.4 1.0 0.2 -1.0 1.0 1.2 -1.6 -1.5 1.0
Number of incorrect matches in round 0.8 1.4 4.9 -0.8 1.0 1.1 -0.9 0.5 -0.1 -1.5 1.7 1.7 -0.2 0.8 2.2 1.3 -0.1
Past tobacco smoking 0.7 1.2 6.5 -0.0 -0.0 0.5 1.6 2.5 1.0 -0.0 -0.6 0.8 -1.4 -1.4 -0.6 0.8 -0.8
Alcohol usually taken with meals 1.0 1.6 7.0 1.0 0.3 -1.1 -1.3 0.3 0.6 -2.6 1.0 1.9 -0.7 -0.3 1.0 1.7 -1.4
Nervous feelings 1.0 1.8 4.2 -2.0 -0.3 1.8 1.1 1.6 -0.8 -1.3 -0.6 1.5 -1.9 -0.1 1.3 1.4 -1.4
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.6 5.0 -0.9 -0.9 2.2 -1.5 -0.3 -0.5 -1.4 1.5 1.4 0.5 1.4 2.1 -0.4 0.1
Hearing difficulty/problems with background noise 0.5 0.7 1.6 -1.1 -0.7 1.2 0.4 1.3 0.4 -0.6 -0.3 1.1 -0.7 0.2 1.2 0.9 -0.7
Hair/balding pattern: Pattern 2 1.7 2.1 5.5 0.8 1.8 -1.4 2.0 1.9 2.3 -0.2 -1.2 0.5 -1.5 -1.8 0.6 1.3 -1.0
Had menopause 1.0 1.3 4.7 -0.4 0.8 0.5 -1.8 -2.2 -1.1 -0.7 1.3 -0.1 0.9 1.7 0.9 -0.5 1.0
Had other major operations 0.4 0.5 2.2 -1.2 -0.1 0.3 -0.3 -0.6 0.0 -0.0 -0.0 -0.6 0.4 1.5 0.7 1.4 0.8
Forced vital capacity (FVC) 0.3 1.1 4.1 0.4 1.7 -1.8 0.7 1.2 2.0 -0.6 0.0 0.4 0.1 0.3 1.0 1.0 0.1
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 1.4 -0.5 0.2 -0.7 0.2 0.1 0.8 0.9 -0.4 -0.9 0.6 0.2 -1.2 -0.8 1.0
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 2.7 -0.8 -1.6 0.6 0.6 0.5 -0.7 -0.1 -0.0 0.1 0.0 -0.2 0.2 -0.9 -0.5
Qualifications: None of the above 0.5 1.0 3.0 -0.3 0.6 0.1 0.3 0.2 -1.7 1.7 -1.5 0.1 0.4 0.1 -1.5 1.1 1.3
Financial difficulties in last 2 years 0.9 1.2 3.5 1.0 0.6 -1.0 0.3 1.1 0.7 -0.8 1.4 1.9 1.0 1.2 1.1 1.5 0.0
Mouth/teeth dental problems 1.3 2.0 5.3 2.2 0.4 -2.3 1.0 -0.1 1.8 1.8 1.2 -1.2 1.5 0.2 -1.1 -0.8 1.9
Heart attack 0.4 0.6 1.8 0.0 0.4 -0.9 0.4 1.3 -0.2 1.2 -1.0 -0.6 -0.3 -0.2 0.3 1.3 0.5
Allergy 0.2 0.5 2.1 0.5 -0.2 -1.0 1.5 1.1 0.8 0.6 -0.3 0.4 0.2 -0.7 -0.9 0.4 0.1
Pain all over the body in last month 0.4 0.4 1.3 -1.1 -0.4 0.8 -0.8 -0.7 -1.0 -0.7 0.3 -0.5 -0.3 -0.0 -0.4 -0.1 -0.9
Diabetes (self-reported) 0.1 0.2 0.5 0.6 -0.2 -0.7 -0.6 -0.6 -0.2 -0.4 -0.1 0.5 0.3 0.7 0.1 0.5 0.3
Hayfever/allergic rhinitis (self-reported) 1.4 1.8 6.4 -2.5 -0.3 2.2 -1.0 -1.1 -2.3 -0.4 -0.8 -1.6 -1.4 -0.1 0.5 -0.6 -0.8
Medication: Ramipril 1.2 1.5 9.7 -0.3 1.0 -0.5 -0.8 0.5 0.9 -1.7 1.0 0.8 -0.7 0.5 3.1 1.6 -0.5
Medication: Simvastatin 0.7 1.0 2.7 0.2 -0.7 -1.6 0.1 -0.5 0.2 0.3 0.8 0.2 1.5 1.6 1.5 1.1 1.1
Fluid intelligence score 0.9 1.8 5.1 2.2 1.4 -1.6 -0.0 -0.3 1.9 -0.3 2.0 1.2 1.2 -0.2 -0.6 -2.0 -0.3
Illnesses of siblings 0.9 1.2 8.0 -0.3 -0.1 0.5 1.0 -0.7 0.6 1.3 -0.2 -1.4 -0.1 -0.2 -1.6 -2.8 0.9
Neuroticism score 0.8 1.6 4.5 -1.1 -0.4 2.1 0.6 1.7 0.1 -1.3 0.2 2.1 -1.5 -0.4 1.0 0.9 -1.8
Weight 0.3 1.6 8.1 0.1 -1.4 -1.0 0.2 -1.1 -0.9 1.4 -0.5 -1.5 0.9 0.9 -2.8 -1.5 1.0
Impedance of arm (right) 0.4 1.7 6.9 -1.1 0.2 0.3 1.5 1.7 -0.2 0.2 -1.5 -1.0 -2.4 -2.6 -0.2 -0.4 -1.3
Arm fat percentage (right) 0.5 1.9 6.6 -0.1 -1.8 -0.3 -0.0 -1.6 -1.1 1.5 -0.1 -1.7 1.2 1.0 -2.6 -2.2 1.0
Trunk fat-free mass 0.1 0.7 2.4 0.4 -0.8 -0.7 -0.2 -0.8 -0.5 0.6 0.4 -0.1 1.1 1.5 -1.6 -0.4 0.9
Hip circumference 0.5 2.1 9.1 0.2 -1.6 -0.9 0.2 -1.4 -0.9 1.7 -0.7 -1.9 1.2 1.2 -3.0 -1.5 1.4
Time employed in main current job 0.9 1.0 3.4 -1.8 -1.0 1.7 0.7 -0.3 -1.4 0.9 -1.4 -0.8 -0.4 0.0 0.2 -0.1 0.8
Alcohol intake versus 10 years previously 0.5 0.8 6.6 -0.9 2.6 -0.3 -0.9 -0.4 0.5 0.1 0.2 -0.9 0.1 -0.0 0.1 -0.8 0.6
Father’s age at death 2.0 2.7 9.2 0.9 1.1 -0.1 -1.5 -2.1 1.5 -0.5 0.7 0.7 2.8 3.0 1.5 1.4 2.1
Worrier / anxious feelings 1.1 2.1 8.9 -1.8 0.6 1.9 0.7 1.0 -0.3 -1.9 -0.3 1.2 -2.1 -1.1 -0.0 0.6 -3.0
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.4 1.7 -0.6 -0.1 0.7 -0.3 -0.0 -0.4 -0.9 -0.2 0.5 -0.1 1.0 1.3 0.3 -0.7
Falls in the last year 0.7 0.9 3.0 -0.8 0.9 1.0 -0.6 -1.0 -0.6 -0.7 0.4 0.8 0.9 1.4 1.7 0.5 1.1
Hair/balding pattern: Pattern 3 0.3 0.4 1.5 -0.7 -1.2 -0.1 -0.3 -1.0 -0.8 0.6 -0.4 -0.6 0.0 -0.1 -0.7 -0.9 0.6
Number of live births 0.6 0.8 3.9 1.0 0.6 -1.1 -1.0 -0.4 0.4 0.2 0.4 0.8 0.6 1.2 -0.3 2.0 0.7
Forced expiratory volume in 1-second (FEV1) 0.2 0.6 2.6 0.3 1.2 -1.6 0.5 1.0 1.6 -0.4 -0.2 -0.0 -0.1 -0.0 0.4 0.1 -0.2
Pulse rate 0.6 1.1 3.9 0.9 -2.0 -0.6 0.4 0.2 -0.5 1.6 -1.0 -0.5 -0.2 -0.8 -1.6 -1.4 -0.3
Happiness 0.6 0.7 2.1 -0.8 0.5 1.4 0.5 -0.2 0.8 -0.4 1.1 0.3 0.6 1.3 1.2 0.7 0.8
Noisy workplace 1.0 1.3 4.0 -0.8 -1.2 1.2 1.1 2.0 -0.2 0.9 -1.5 0.2 -1.7 -1.7 0.0 0.4 0.1
Qualifications: A levels/AS levels or equivalent 1.5 3.4 9.4 2.5 2.6 -1.3 -1.3 0.4 3.1 -1.9 2.4 2.9 0.8 -0.2 1.2 -0.4 -1.3
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 3.4 0.2 0.5 -0.0 0.3 -0.7 0.3 1.1 0.5 -0.9 1.6 0.7 0.4 -0.9 1.8
Mouth/teeth dental problems: Dentures 1.1 1.9 7.1 -2.7 -0.8 1.3 0.2 0.8 -2.5 0.2 -2.4 -0.5 -1.2 -0.9 -0.5 1.1 -1.1
Asthma 0.3 0.6 1.7 0.1 0.5 0.3 -1.2 -0.8 -0.1 -0.7 1.0 0.4 0.7 1.3 1.0 -0.2 0.6
Medication: Ibuprofen (e.g. Nurofen) 1.6 2.1 5.5 -2.1 -1.2 2.3 -2.1 -2.2 -1.6 -0.4 0.0 -0.9 0.9 1.1 1.1 -1.3 0.3
Medication: Cholesterol lowering 0.4 0.7 2.0 0.5 0.8 -1.1 0.5 0.2 0.6 1.2 -0.3 -0.1 1.1 0.7 0.2 1.2 1.4
Depression (self-reported) 0.6 0.7 4.2 -0.3 0.4 0.3 2.0 0.8 -0.0 0.6 -1.2 -1.3 -0.7 -0.2 -0.9 -0.3 0.3
Medication: Lansoprazole 0.4 0.5 1.3 -0.8 1.1 0.0 0.4 0.6 -0.4 0.7 -1.1 -0.4 -1.1 -0.5 0.7 0.7 0.1
Prospective memory result 0.5 0.6 1.4 -0.4 0.2 0.6 -0.1 0.6 -0.7 -0.9 -0.8 -0.0 -0.9 -0.5 1.2 1.2 -0.9
Lung cancer (father) 0.9 1.1 5.2 -0.6 1.1 -0.2 1.4 0.7 0.3 1.4 -2.3 -1.1 -0.7 -0.9 -0.0 1.1 0.4
Illnesses of mother 1.1 1.3 4.8 1.3 1.8 -1.3 -0.6 0.1 1.5 -1.0 2.2 1.4 0.7 0.3 0.3 0.7 -0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.7 2.7 0.1 1.6 -0.9 0.7 0.8 1.6 -0.4 -0.2 0.6 0.0 0.5 1.1 0.7 0.6
Pulse wave Arterial Stiffness index 0.9 1.0 3.8 -1.3 -1.6 0.8 -0.6 -0.1 -1.9 -0.8 -0.1 0.2 -1.3 -0.8 -0.5 -0.3 -1.2
Impedance of arm (left) 0.7 3.4 13.8 -1.3 0.1 0.5 1.4 2.3 -0.9 -0.5 -2.1 -0.9 -3.7 -3.4 -0.5 0.3 -2.6
Arm fat mass (right) 0.5 1.9 7.6 0.0 -1.6 -0.6 -0.1 -1.6 -1.1 1.4 -0.0 -1.4 1.5 1.4 -2.8 -1.8 1.1
Trunk predicted mass 0.1 0.7 2.6 0.4 -0.9 -0.8 -0.2 -0.9 -0.6 0.6 0.4 -0.1 1.1 1.5 -1.6 -0.4 0.8
Standing height 0.1 1.3 4.6 -0.8 0.2 -1.1 1.3 1.8 -0.3 0.0 -1.5 -0.2 -2.1 -1.5 -0.7 0.9 -0.9
Length of working week for main job 0.5 0.5 1.6 0.9 -1.1 -0.5 0.5 -0.8 0.3 0.9 -0.4 -0.6 1.3 0.5 0.1 -0.2 1.0
Exposure to tobacco smoke at home 0.6 0.7 1.8 -0.9 -1.3 0.8 0.2 -0.3 -1.0 1.0 -0.3 -1.1 0.0 0.0 -1.2 -1.0 0.2
Breastfed as a baby 0.3 0.4 1.1 0.0 0.7 0.2 -1.1 -0.8 -0.3 -0.8 0.5 -0.0 0.3 -0.0 0.7 0.8 -0.7
Tense / ‘highly strung’ 0.2 0.3 1.4 -0.6 -0.1 1.1 0.4 1.2 -0.3 0.3 0.0 0.9 -0.5 0.0 -0.3 -0.1 -0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 2.5 0.5 -0.2 0.5 -0.6 -0.6 -0.3 -0.5 -0.1 1.2 0.7 1.6 0.3 -0.3 -0.3
Hair/balding pattern: Pattern 4 0.8 1.9 4.8 0.1 1.1 0.6 -0.1 1.8 -0.0 -1.8 1.5 2.2 -1.1 -0.3 1.8 2.1 -1.7
Birth weight of first child 0.3 0.5 3.2 0.5 -0.2 1.0 -1.8 -1.1 -0.2 -0.3 -0.2 -0.3 0.5 0.3 0.6 -0.2 0.7
Peak expiratory flow (PEF) 0.1 0.2 0.9 0.3 0.9 -0.7 -0.0 -0.0 0.5 -0.7 0.1 -0.1 -0.0 0.5 0.2 -0.5 0.0
Pulse wave reflection index 0.3 0.3 1.5 -1.0 -1.2 0.7 0.1 0.2 -1.0 -0.4 0.1 0.3 -0.0 0.0 -0.6 0.2 -0.4
Ever highly irritable/argumentative for 2 days 0.2 0.3 0.9 0.3 -0.4 -0.1 -0.0 -0.0 0.4 -0.2 -0.4 0.6 0.7 0.8 0.5 0.6 0.9
Loud music exposure frequency 1.3 1.4 4.5 -1.5 -1.6 1.9 0.3 0.8 -0.8 -0.7 -0.5 0.4 -2.1 -1.1 0.3 -0.0 -1.7
Qualifications: O levels/GCSEs or equivalent 1.5 2.4 7.2 1.3 -0.9 1.2 -2.7 -2.6 -0.2 -2.2 1.5 0.7 1.2 1.0 0.7 -2.1 -0.9
Mouth/teeth dental problems: Bleeding gums 1.9 2.5 7.8 0.1 -0.6 2.1 -1.7 -0.2 -0.9 -2.8 1.0 2.6 -0.9 0.0 2.3 0.5 -2.1
Blood clot in the leg (DVT) 0.8 1.1 3.1 1.1 0.9 -0.8 1.5 1.7 0.8 1.0 -0.1 0.1 -0.8 -1.2 -1.8 0.1 -0.7
Medication: Paracetamol 1.1 1.8 5.8 -1.8 -1.6 2.0 -0.8 -0.8 -2.4 0.0 -1.2 -1.9 -1.0 -0.1 -0.1 -1.0 -0.9
Headache pain in last month 0.3 0.5 2.3 0.0 -0.1 -0.3 0.2 -0.5 0.9 0.2 -0.0 -0.4 1.0 1.3 0.6 0.1 1.5
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 2.3 -0.5 -1.4 1.1 -0.8 -0.6 -1.1 -0.9 0.3 -0.1 -0.5 -0.1 -0.6 -1.5 -1.1
Glaucoma (self-reported) 0.9 1.1 3.7 0.1 0.3 0.3 -1.7 -0.6 -0.4 -1.1 1.9 1.0 0.9 1.5 1.6 0.1 0.1
Gout (self-reported) 0.9 1.3 5.1 0.2 1.4 -0.8 0.6 -0.3 0.9 2.3 -0.3 -1.7 1.1 -0.2 0.4 -0.5 2.1
Hypothyroidism/myxoedema (self-reported) 0.3 0.6 2.3 0.6 0.5 -0.7 -0.2 -0.9 -0.1 -0.7 0.0 0.7 1.0 1.5 0.3 1.2 0.6
Medication: Amlodipine 0.3 0.4 1.6 0.3 0.3 -1.3 0.6 0.7 0.5 0.0 0.0 -0.1 -0.4 -0.7 -0.6 0.5 -1.1
Medication: Ventolin 100micrograms inhaler 0.1 0.2 0.6 -0.0 0.5 0.4 -0.3 -0.3 -0.1 -0.1 -0.2 -0.7 0.1 0.8 0.1 -0.7 0.2
Birth weight 0.4 0.8 4.3 0.7 0.1 -0.9 0.0 -0.4 0.6 0.5 0.3 -0.2 2.1 1.4 -0.5 -0.3 1.5
Chronic bronchitis/emphysema (mother) 1.1 1.3 5.0 -1.5 -1.4 1.2 -1.4 -0.8 -2.2 -1.1 -0.1 -0.0 -0.1 0.6 -0.0 -0.7 -1.6
High blood pressure (siblings) 0.9 1.3 7.1 0.7 -0.1 -0.3 -1.0 0.3 -0.2 -1.4 -0.2 1.3 0.8 0.8 1.8 2.7 -0.7
Forced vital capacity (FVC), Best measure 0.3 1.3 4.9 0.2 2.2 -1.0 0.7 1.0 1.9 -0.5 -0.1 0.8 0.1 0.5 1.8 1.3 0.8
Body fat percentage 0.4 1.6 6.0 -0.1 -1.7 -0.3 0.2 -1.3 -1.2 1.5 -0.3 -1.6 0.8 0.5 -2.4 -1.9 1.0
Leg fat percentage (right) 0.7 2.4 5.2 -0.3 -1.9 0.3 -0.5 -2.2 -1.3 1.6 0.2 -1.8 1.7 1.4 -2.1 -2.3 1.6
Arm fat-free mass (right) 0.2 0.9 3.2 0.7 -1.1 -1.2 -0.0 -0.9 -0.4 0.8 0.5 -0.1 1.2 1.4 -1.8 -0.6 0.8
Exposure to tobacco smoke outside home 0.8 1.0 5.9 -1.0 -1.1 1.3 -0.4 -0.1 -2.4 0.3 -0.3 -0.4 -0.7 -1.0 -1.2 -0.4 -1.0
Comparative body size at age 10 0.3 0.9 3.6 -1.3 -1.6 0.4 -0.3 -0.6 -1.9 -0.2 -0.3 -1.0 -0.6 0.4 -0.7 -0.8 -1.2
Number of full brothers 1.4 1.8 4.6 2.0 1.2 -2.1 0.9 0.4 2.1 1.6 0.8 -0.7 1.4 0.0 -1.2 0.4 1.5
Worry too long after embarrassment 1.7 2.9 8.8 -1.5 -1.0 1.0 2.6 3.0 -0.3 0.5 -1.4 -0.7 -2.9 -2.1 -0.9 0.3 -2.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 2.1 0.6 -0.2 0.2 0.0 0.2 -0.4 -1.0 0.2 1.0 -0.2 -0.1 0.7 -0.4 -1.4
Wheeze or whistling in the chest in last year 0.6 1.1 5.8 -0.8 -0.3 0.6 -1.4 -1.2 -1.1 -0.5 0.7 0.4 0.9 2.4 1.2 -0.2 0.7
Number of children fathered 1.4 1.6 5.1 2.1 0.8 -0.8 -1.1 -0.8 0.4 -1.3 0.6 2.0 1.3 0.8 1.2 2.2 -0.0
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.4 1.6 0.6 -0.7 -1.0 1.3 0.3 0.8 -0.1 -0.0 -0.4 -0.2 -0.3 -0.6 -1.1 0.0
Age at first live birth 0.4 0.8 2.9 -0.3 1.4 0.2 -0.3 0.5 0.6 -0.9 0.2 1.7 0.0 0.2 1.6 0.9 -0.8
Pulse wave peak to peak time 0.6 0.7 2.7 0.9 1.5 -0.6 0.6 0.3 1.6 0.6 -0.1 -0.2 0.9 0.7 0.6 0.4 0.9
Health satisfaction 0.6 0.8 2.7 -1.2 0.6 0.4 -0.1 -0.5 -0.5 1.0 -1.7 -1.6 -0.5 0.5 0.3 0.7 1.1
Shortness of breath walking on level ground 0.3 0.4 1.7 0.1 0.6 0.4 0.1 0.4 0.4 0.1 -0.9 0.8 -0.8 -0.0 0.6 1.3 0.4
Qualifications: College or University degree 0.9 2.7 9.2 2.0 2.7 -1.8 1.1 1.9 3.0 -0.2 0.2 1.6 0.1 -1.8 0.6 0.1 -1.8
Eye problems/disorders: None of the above 0.8 0.9 2.5 0.8 0.5 -1.0 0.7 -0.3 1.6 1.3 -0.9 -1.2 0.5 -0.2 -1.4 -0.1 1.4
Mouth/teeth dental problems: Loose teeth 1.2 1.5 6.7 -0.9 -1.4 0.5 -1.1 -2.1 -0.4 0.3 -0.3 -1.9 0.6 0.2 -0.8 -2.6 0.5
Emphysema/chronic bronchitis 0.8 0.9 2.5 -0.7 -0.4 1.4 -1.5 -1.6 -1.0 0.2 -0.9 -1.0 0.1 0.9 0.4 -0.7 1.0
Medication for pain relief, constipation, heartburn 0.9 1.5 8.9 2.2 0.2 -2.1 0.4 -0.2 0.8 0.3 -0.3 0.3 0.2 -0.8 -3.0 -0.6 -0.6
Neck or shoulder pain in last month 0.4 0.6 3.6 -0.9 -0.1 0.3 -0.3 -0.7 -1.0 0.2 -0.4 -0.5 0.4 1.9 0.1 0.1 1.1
Medication: Blood pressure 0.9 1.5 5.0 0.8 1.8 -1.7 1.5 1.3 2.2 1.1 -0.1 0.4 0.3 -0.2 0.3 1.5 1.2
Angina (self-reported) 1.1 1.5 3.8 -1.8 -1.1 0.9 -0.3 0.7 -1.6 -0.8 0.7 0.0 -1.9 -0.9 0.1 -1.9 -1.9
Migraine (self-reported) 0.4 0.5 1.7 0.8 0.2 -1.0 -0.3 -0.9 0.6 0.2 0.1 -0.4 1.3 1.1 0.1 -0.1 1.0
Medication: Ibuprofen 2.0 2.4 6.3 -2.1 -1.5 2.2 -2.0 -2.5 -1.5 0.4 -0.4 -1.7 1.1 0.9 0.5 -2.1 0.7
Medication: Allopurinol 1.1 1.4 5.5 0.5 1.6 -1.0 1.1 0.5 1.3 2.4 -0.5 -1.1 1.1 -0.1 0.3 0.2 2.1
Medication: Omeprazole 1.0 1.2 5.2 1.2 0.9 -0.9 -0.2 0.2 0.6 -1.4 1.1 1.4 0.8 0.9 2.3 1.1 -0.3
Medication: Seretide 50 evohaler 0.8 0.9 2.7 0.7 1.1 -0.5 -1.6 -1.6 -0.6 -0.3 0.6 0.4 1.3 1.6 -0.3 -0.1 0.4
Mean time to correctly identify matches 1.4 2.7 9.7 -1.6 -1.6 2.3 -1.8 -0.5 -3.1 -2.2 0.6 1.6 -0.9 0.7 0.6 0.3 -2.3
Heart disease (mother) 0.9 1.1 3.6 0.7 1.2 -0.6 1.7 1.9 0.7 1.0 -1.0 0.5 -0.5 -0.5 0.4 1.9 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 1.5 -0.1 1.2 -0.6 -0.4 -0.2 0.6 -0.5 1.0 0.1 0.2 -0.1 1.1 0.3 0.1
Whole body fat mass 0.4 1.8 7.7 -0.1 -1.8 -0.6 0.3 -1.2 -1.3 1.6 -0.4 -1.6 0.9 0.8 -2.8 -1.7 1.1
Leg fat mass (right) 0.5 2.0 5.6 -0.2 -1.8 0.0 -0.3 -1.8 -1.3 1.6 -0.1 -1.7 1.5 1.2 -2.4 -1.9 1.3
Arm predicted mass (right) 0.2 0.9 3.1 0.8 -1.0 -0.9 -0.2 -1.1 -0.3 0.6 0.7 -0.0 1.4 1.5 -1.8 -0.6 0.8
Pulse rate, automated reading 0.4 1.2 2.6 0.5 -0.9 -0.2 -0.3 -1.6 0.2 1.5 -1.3 -0.7 1.4 0.8 -1.0 -1.6 1.4
Alcohol intake frequency. 1.3 2.9 8.5 -0.1 -1.4 -1.7 -0.1 -1.5 -0.9 2.2 -0.9 -2.9 1.6 1.8 -2.0 -0.9 2.9
Comparative height size at age 10 0.1 0.7 4.8 0.2 0.5 -2.2 0.5 1.2 1.1 -0.1 -0.5 -0.0 -0.7 -0.5 0.1 0.9 0.0
Number of full sisters 1.0 1.2 2.6 0.1 -0.1 0.7 -1.6 -1.3 -1.4 -1.5 1.1 0.9 1.5 1.6 0.9 -0.1 -0.3
Suffer from ‘nerves’ 1.2 1.9 4.9 -2.0 0.2 2.2 0.4 1.4 0.0 -1.9 0.9 1.9 -1.1 0.6 2.1 0.8 -1.0
Overall health rating 0.3 0.7 3.3 -0.7 0.1 1.2 -0.5 -0.7 -0.1 0.1 0.2 -0.2 0.7 1.8 0.6 0.8 1.3
Chest pain or discomfort 0.8 1.2 3.9 -1.9 -0.8 1.4 -0.1 -0.1 -2.0 -0.6 -1.3 0.0 -1.0 1.1 0.5 1.3 -0.4
Had major operations 1.8 2.1 6.5 0.1 -0.3 1.0 -2.2 -2.5 -1.0 -0.9 1.9 0.8 1.7 1.9 0.1 -1.9 0.5
Age at last live birth 1.1 1.6 4.9 0.9 2.1 -1.3 -1.2 0.2 0.8 -1.3 0.8 2.2 0.8 1.0 1.5 1.6 -0.3
Family relationship satisfaction 0.4 0.5 1.3 0.2 1.1 -0.3 -0.2 0.3 1.0 0.2 0.8 0.8 1.1 0.3 1.0 1.0 0.5
Leg pain on walking 0.5 0.7 2.5 -0.8 0.6 1.1 0.3 0.7 -1.6 0.0 -0.9 -0.6 -1.2 -0.4 -0.4 0.5 -0.9
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 2.6 -0.8 -0.8 0.4 -0.2 -1.1 -0.2 -0.5 -0.5 -1.6 0.0 0.9 -0.2 -0.7 0.3
Commuting to job workplace: Car/motor vehicle 1.5 1.7 7.0 -0.6 -0.8 0.8 1.0 1.0 -1.0 1.0 -2.7 -1.8 -2.0 -1.4 -0.8 0.9 -0.3
Illness, injury, bereavement, stress in last 2 years 1.2 1.5 3.9 -1.2 -0.6 2.0 -1.8 -1.8 -1.4 -1.1 -0.7 -0.6 -0.9 -0.2 -0.6 -1.4 -1.3
Medication: Aspirin 0.7 0.9 3.6 0.0 -0.2 -0.5 1.2 1.9 0.4 -0.3 0.9 0.7 -0.9 -1.1 1.2 0.9 -1.0
Supplements: Vitamin C 1.4 1.6 5.1 0.3 1.4 -1.7 0.3 -1.2 2.0 0.9 0.8 -1.1 1.9 1.0 0.1 -0.1 2.3
Knee pain experienced in last month 0.6 0.9 3.1 -0.2 1.2 1.2 -1.7 -0.7 -0.0 -0.9 0.6 0.4 0.4 1.2 1.8 0.1 0.7
Hypertension (Self-reported) 0.5 1.4 4.8 -0.9 0.1 -0.8 1.1 2.1 0.3 -0.5 -0.1 0.5 -1.6 -1.2 0.8 2.2 -1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.3 1.6 3.3 1.8 1.2 -0.9 -1.6 -1.7 1.1 -0.7 0.8 0.7 1.2 1.8 1.3 -0.3 1.3
Illnesses of father: Heart disease 0.3 0.4 1.5 0.5 -0.3 -0.2 0.0 0.9 -0.0 -0.6 0.1 1.2 0.3 0.8 0.4 1.1 -0.4
Illnesses of siblings: Diabetes 0.7 0.9 3.3 -1.6 -0.2 0.5 0.1 0.8 -1.4 0.8 0.0 -1.8 -1.3 -1.0 -0.4 -0.4 -0.5
Smoking status: Previous 1.2 1.7 6.6 0.0 0.7 -0.3 -2.1 -2.6 -1.1 -0.9 1.4 -0.1 1.9 2.1 0.9 -0.1 0.7
Forced expiratory volume in 1-second (FEV1), predicted 0.7 1.5 3.7 -0.3 1.8 -0.5 1.9 1.3 1.1 0.1 -1.8 -0.8 -1.4 -0.8 1.1 1.7 0.2
Whole body fat-free mass 0.1 0.8 3.8 0.5 -1.0 -1.0 -0.1 -0.7 -0.6 0.7 0.3 -0.2 0.9 1.3 -1.9 -0.5 0.7
Leg fat-free mass (right) 0.1 0.7 4.6 0.6 -0.9 -1.3 0.1 -0.3 -0.5 0.5 0.1 -0.4 0.5 0.8 -2.1 -0.7 0.3
Arm fat percentage (left) 0.4 1.8 7.7 -0.1 -1.7 -0.2 -0.1 -1.4 -1.4 1.3 -0.5 -1.6 0.9 0.8 -2.8 -1.9 0.6
Average weekly red wine intake 0.3 0.5 2.0 -0.5 0.0 0.4 0.5 0.5 0.2 -0.4 -0.4 -0.4 -1.3 -1.4 -0.5 0.1 -1.1
Handedness (chirality/laterality): Left-handed 1.0 1.2 7.3 1.2 -0.4 -0.3 -0.4 0.7 0.0 -1.4 0.4 2.7 0.6 0.7 1.1 1.7 -0.2
Mood swings 0.8 1.4 10.3 -1.6 -1.7 3.2 0.5 0.4 -0.8 -0.5 -0.3 1.0 -0.6 -0.6 -0.0 -0.2 -1.1
Loneliness, isolation 0.3 0.5 1.3 -0.3 -0.6 0.7 -0.4 -0.2 0.5 -0.2 1.1 0.5 0.8 1.0 1.0 -0.9 0.4
Long-standing illness, disability or infirmity 0.2 0.2 0.8 0.6 -0.4 -0.5 0.7 0.9 -0.6 0.2 -0.1 -0.4 0.4 0.5 -0.1 0.6 -0.0
Ever had bowel cancer screening 0.6 0.7 2.5 -1.0 1.4 -0.0 0.5 -1.2 -0.9 0.6 -0.8 -1.6 0.5 0.3 0.0 0.1 1.0
Diabetes diagnosed by doctor 0.1 0.2 0.6 0.2 -0.2 -0.8 0.2 0.2 0.3 0.2 -0.2 0.1 0.2 0.6 0.4 0.5 0.7
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.5 1.5 0.6 0.4 -0.4 0.2 -1.0 0.2 0.4 -0.7 -0.9 0.9 1.2 0.4 -0.3 0.8
Friendships satisfaction 1.0 1.2 4.7 -0.5 -0.2 0.7 1.5 2.2 1.2 -0.5 1.4 1.0 -0.7 -1.4 0.4 0.4 -1.3
Qualifications: nursing, teaching 1.6 2.5 6.2 2.4 -0.1 -2.2 -0.4 0.8 1.8 -1.9 1.7 2.3 0.6 0.2 2.5 1.0 -1.2
Commuting to job workplace: Walk 1.2 1.3 4.1 0.1 0.0 0.8 -1.1 -0.1 -0.5 -1.9 1.2 1.0 -1.2 -0.9 0.8 -1.6 -2.0
Eye problems/disorders: Cataract 0.5 0.5 2.1 -0.6 0.7 0.2 0.6 1.1 0.3 -0.5 0.4 0.9 -0.2 -0.1 1.5 0.5 -1.1
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 2.2 -0.1 1.5 0.7 -0.5 -0.7 -0.0 -0.4 -0.7 -0.8 -0.1 0.7 -0.6 -0.5 -0.7
Medication for cholesterol 0.5 0.7 3.0 0.4 1.0 1.7 -0.3 -0.4 -0.9 -0.5 -0.2 0.3 -0.7 -0.6 -1.4 -0.8 -0.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.2 1.5 3.7 -1.9 -1.5 1.9 -1.0 -0.9 -1.6 -0.0 -0.6 -1.2 -0.5 0.9 1.7 0.0 0.9
Back pain experienced in last month 0.7 1.1 4.2 -1.2 1.4 1.2 -0.6 0.8 0.5 -1.3 0.6 1.3 -0.8 0.1 2.1 0.5 0.0
Mineral and other dietary supplements 2.7 3.6 12.0 -0.4 -2.1 0.0 3.1 3.5 -0.3 1.9 -2.5 -0.6 -2.0 -2.4 -1.9 0.6 -0.5
Breast cancer (self-reported) 0.7 0.8 6.5 -0.1 2.5 -0.8 -0.1 0.6 0.7 0.2 -1.4 -0.1 -0.3 -0.4 0.9 0.5 0.4
Asthma (self-reported) 0.3 0.6 1.8 0.0 0.7 0.3 -1.0 -0.7 -0.1 -0.7 1.2 0.5 0.7 1.4 1.3 -0.1 0.6
Osteoporosis (self-reported) 0.5 0.7 2.6 0.7 1.2 -0.7 1.3 0.7 0.9 0.1 -0.8 0.2 -0.4 -0.3 -0.5 1.6 0.1
Osteoarthritis (self-reported) 0.5 0.7 2.9 0.2 1.7 0.1 -0.9 -0.4 -0.8 -0.4 -0.1 0.5 0.8 1.0 -0.2 1.6 -0.5
Medication: Aspirin 0.9 1.1 5.0 0.3 -0.1 -0.8 1.5 2.2 0.6 -0.1 1.2 1.3 -0.6 -0.9 1.2 1.3 -0.7
Medication: Gliclazide 1.3 1.5 4.3 -1.7 -0.1 1.2 -0.6 1.0 -1.7 -1.5 2.1 0.6 -1.0 -0.1 1.2 0.1 -1.6
Illnesses of father: None of the above (group 1) 0.8 1.0 3.2 -1.3 0.7 0.6 -0.8 -1.6 -0.2 0.5 -1.0 -1.8 0.1 0.2 -0.2 -1.0 1.4
Smoking status: Current 0.5 0.8 4.7 -0.2 -2.2 0.1 1.2 1.1 -0.0 0.9 -0.7 -0.2 -1.0 -1.1 -0.2 -0.6 -0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.0 3.1 -1.4 1.8 0.9 -1.0 -0.0 0.1 -1.2 0.2 0.8 -0.8 0.4 1.6 0.9 -0.8
Whole body water mass 0.2 0.9 4.2 0.7 -1.1 -1.1 -0.0 -0.8 -0.5 0.8 0.3 -0.2 1.1 1.4 -2.0 -0.5 0.8
Leg predicted mass (right) 0.1 0.7 4.7 0.6 -0.8 -1.3 0.0 -0.4 -0.5 0.5 0.1 -0.4 0.5 0.8 -2.2 -0.7 0.3
Arm fat mass (left) 0.4 1.8 7.9 0.0 -1.8 -0.5 -0.1 -1.5 -1.3 1.3 -0.2 -1.5 1.1 1.1 -2.8 -1.8 0.8
Number of self-reported non-cancer illnesses 0.8 1.5 6.8 -1.6 0.3 0.9 -1.6 -0.9 -0.4 -1.0 0.6 -0.1 0.5 1.6 2.6 1.4 0.6
Average weekly champagne plus white wine intake 0.6 0.8 3.5 0.0 1.9 0.8 0.0 0.8 -0.2 -1.0 -0.5 1.4 -0.7 -0.7 0.1 1.3 -0.9
Miserableness 0.4 0.7 3.5 0.1 -1.9 1.3 -0.7 -0.1 -0.2 -0.7 0.5 1.2 0.1 -0.0 -0.4 -1.0 -0.8
Guilty feelings 0.7 1.0 3.8 -0.0 1.4 0.3 0.0 0.7 1.3 -0.9 0.7 1.9 0.1 1.2 1.0 1.3 -0.7
Wears glasses or contact lenses 1.0 1.2 4.4 1.0 2.1 -1.2 1.0 0.0 1.8 -0.8 1.0 1.2 0.6 0.6 0.8 0.9 0.3
Ever taken oral contraceptive pill 0.4 0.5 2.5 -0.2 -1.6 0.8 0.6 0.2 -0.7 0.7 0.4 -0.2 0.8 0.4 -0.6 -0.8 0.1
Hearing aid user 1.7 1.9 6.2 1.8 0.7 -2.1 -0.6 -0.7 1.4 0.8 1.0 0.7 2.0 1.6 0.6 0.9 2.5
Mother’s age at death 0.4 0.5 1.5 0.8 -1.2 0.5 -0.5 -0.7 -1.2 -0.5 -0.5 0.9 -0.4 -0.0 -0.3 -0.3 -0.4
Financial situation satisfaction 1.2 1.4 8.1 -0.5 0.8 0.9 -0.8 -1.4 -0.1 -0.5 1.0 0.7 1.8 2.8 0.8 0.3 1.4
Tinnitus: Yes, now most or all of the time 0.3 0.4 1.7 -0.7 0.5 -0.2 0.3 -0.2 0.8 0.0 -0.3 -1.3 -0.6 -0.1 0.9 -1.1 0.1
Commuting to job workplace: Public transport 1.6 1.9 4.5 -0.1 1.5 0.4 -1.5 -1.3 1.7 -0.9 2.1 1.4 1.7 1.8 1.1 -1.4 0.7
Eye problems/disorders: Glaucoma 0.3 0.3 1.2 -0.4 -0.9 0.2 -0.7 0.1 -1.1 -0.5 0.6 0.1 -0.4 0.2 0.8 0.1 -0.7
Medication: Blood pressure 0.3 0.5 1.6 -0.3 -1.1 -0.6 1.1 1.3 0.4 -0.0 0.4 0.0 -0.6 0.2 1.0 0.9 -0.0
Pain type(s) experienced in last month: Hip pain 0.4 0.5 1.3 0.1 -0.3 0.2 -0.9 -0.4 0.3 0.2 0.9 0.6 0.9 1.1 0.9 0.4 1.0
Supplements: Fish oil (including cod liver oil) 1.7 2.2 7.4 -0.3 1.9 0.5 -2.0 -2.7 0.3 -1.6 2.2 -0.0 0.9 1.4 1.6 -1.4 0.0
High cholesterol (Self-reported) 1.0 1.8 4.9 -0.7 -0.5 0.7 -1.7 -1.4 -1.1 -0.3 1.8 0.9 1.9 2.0 2.2 0.4 0.8
Medication: Bendroflumethiazide 0.6 1.0 2.9 0.4 0.2 -1.4 1.6 0.6 1.5 1.4 -0.4 -0.6 0.4 0.1 -0.3 0.9 1.7
Medication: Paracetamol 1.3 2.0 5.9 -1.6 -2.2 1.6 -0.8 -1.3 -2.4 0.6 -1.1 -2.4 -0.7 0.1 -0.6 -1.4 -0.2
Medication: Lisinopril 1.2 1.5 7.4 1.0 0.3 -0.9 2.3 2.7 1.0 0.9 -0.7 1.0 -0.6 -0.7 -0.0 1.5 -0.2
Medication: Atorvastatin 0.4 0.5 2.5 -1.1 0.2 1.6 -0.1 0.6 -0.4 0.2 0.3 0.6 -0.0 0.6 1.1 0.7 0.4
Illnesses of father: High blood pressure 0.5 0.6 3.3 -0.4 -0.5 1.8 -0.8 -0.6 -0.9 -0.7 0.4 0.3 0.3 0.8 0.9 -0.2 -0.8
Alcohol drinker status: Never 1.8 2.1 4.9 -2.1 -1.2 0.9 0.5 -1.2 -1.9 1.3 -1.5 -2.1 0.5 1.8 0.1 0.8 2.2
Ever smoked 1.1 1.8 8.7 -0.1 -0.7 0.2 -2.2 -3.0 -1.1 -0.4 1.1 -0.3 1.6 1.7 1.2 -1.3 0.5
Basal metabolic rate 0.2 1.1 5.5 0.5 -1.2 -1.1 0.1 -0.8 -0.7 1.0 0.1 -0.6 1.0 1.3 -2.3 -0.8 0.9
Leg fat percentage (left) 0.5 1.9 4.5 -0.0 -1.8 -0.1 -0.6 -2.1 -1.1 1.1 0.4 -1.4 1.6 1.4 -1.9 -2.1 1.2
Arm fat-free mass (left) 0.2 1.3 3.0 1.0 -1.3 -1.3 0.2 -1.0 -0.1 0.8 0.9 -0.0 1.7 1.7 -1.7 -0.9 1.2
Number of operations (self-reported) 0.5 0.7 3.1 -0.3 -0.5 0.6 -1.0 -1.8 -0.6 -0.7 0.5 -0.1 0.7 1.6 0.6 -0.2 0.7
Average weekly beer plus cider intake 0.5 0.8 3.0 0.3 0.9 -1.0 1.7 1.2 0.9 0.8 0.6 0.7 0.9 0.3 -0.4 0.2 1.0
Irritability 1.0 1.6 4.6 0.3 -0.3 1.8 -1.0 -1.2 0.1 -0.7 1.3 1.9 2.0 2.1 0.6 -0.7 1.2
Risk taking 0.5 0.7 5.1 0.6 2.3 -0.6 -0.3 -0.5 0.8 0.2 -0.3 -1.2 0.7 -0.0 -0.4 0.7 0.7
Ever had prostate specific antigen (PSA) test 0.2 0.2 1.2 -0.6 0.9 -1.1 -0.1 -0.5 -0.0 -0.2 -0.2 -0.8 -0.2 -0.1 0.0 -0.1 -0.3
Fractured/broken bones in last 5 years 0.2 0.2 0.7 0.6 -0.0 -0.6 0.2 -0.5 0.2 0.2 0.5 -0.4 -0.0 0.0 -0.6 -0.8 0.8
Age started oral contraceptive pill 0.4 0.5 1.6 -0.6 -0.3 1.0 -0.7 -0.7 -0.9 0.5 0.5 0.1 0.8 1.3 0.6 0.3 0.9
Diastolic blood pressure, automated reading 1.7 5.4 12.9 -0.7 -2.3 0.2 3.1 1.4 -1.8 2.1 -3.3 -3.2 -1.8 -3.1 -3.6 -1.5 -1.0
Ever depressed for a whole week 0.5 0.6 2.9 0.4 -1.7 -0.0 0.9 0.7 0.7 0.8 -0.8 0.4 0.5 -0.6 -0.7 -0.7 0.0
Unable to work because of sickness or disability 0.5 0.6 2.2 0.0 0.7 -0.1 0.1 -1.1 -1.1 0.6 -1.0 -0.4 0.4 1.4 0.2 0.0 1.5
Commuting to job workplace: Cycle 2.0 2.4 7.9 1.9 2.4 -2.5 1.3 1.9 2.8 0.3 0.4 1.7 0.4 0.3 -0.4 0.7 1.1
Myopia 1.0 1.4 4.5 0.8 1.4 -0.3 -0.7 -0.2 1.3 -2.1 2.0 1.8 0.9 -0.0 0.9 -0.4 -1.3
Vascular/heart problems diagnosed by doctor 0.3 1.0 2.7 1.4 0.6 0.4 -0.6 -1.5 0.6 0.3 0.5 0.2 1.6 1.2 -0.5 -1.0 1.6
Cholesterol lowering medication 1.3 1.9 5.7 -0.0 -1.4 -0.7 -1.5 -0.8 -0.6 -1.1 2.4 1.5 1.4 1.9 2.3 1.0 0.1
Medication: Omeprazole (e.g. Zanprol) 1.4 1.7 9.1 0.5 1.5 -0.2 -0.5 0.2 0.6 -2.0 2.0 1.6 0.3 0.7 3.0 0.8 -0.4
Pain experienced in last month 0.6 0.9 4.7 1.1 -0.8 -1.0 0.8 0.5 -0.4 0.7 -0.6 -0.2 -0.5 -1.3 -2.2 -0.0 -1.2
Supplements: Calcium 0.7 0.7 1.9 -0.4 1.2 -0.5 0.1 1.3 0.5 -1.0 -0.1 0.2 -1.4 -1.0 0.1 1.1 -1.3
Basal cell carcinoma (self-reported) 0.5 0.5 2.7 0.0 1.2 -0.5 0.4 0.1 0.6 0.2 -1.2 -0.2 -0.4 -0.8 1.6 0.1 0.5
Heart attack/myocardial infarction (self-reported) 0.5 0.6 1.8 -0.1 0.4 -0.9 0.5 1.2 -0.4 1.3 -1.2 -1.0 -0.4 -0.3 -0.1 1.1 0.5
Deep venous thrombosis (DVT) (self-reported) 0.8 1.1 3.4 0.8 0.6 -0.4 1.8 1.8 0.4 1.1 -0.5 0.0 -0.9 -1.1 -1.8 0.3 -0.6
Heart disease (siblings) 0.2 0.3 1.0 -0.1 0.4 -0.7 0.5 0.8 -0.5 0.6 -0.0 -0.2 -0.4 -0.7 0.0 1.0 0.0
Alcohol drinker status: Previous 0.2 0.3 0.9 0.2 -0.5 -0.7 -0.1 0.5 0.2 -0.5 0.8 0.5 0.3 0.2 1.0 0.9 0.1
Pack years of smoking 0.3 0.4 2.8 -0.0 -1.7 -0.7 0.4 0.7 0.6 0.1 0.4 0.4 -0.2 -0.6 0.9 -0.6 0.2
Impedance of whole body 0.6 2.9 11.9 -1.0 0.3 0.3 1.7 2.3 -0.1 -0.4 -1.8 -0.6 -3.3 -3.4 0.3 0.2 -2.1
Leg fat mass (left) 0.4 1.7 5.1 -0.1 -1.8 -0.3 -0.1 -1.5 -1.1 1.5 0.0 -1.4 1.4 1.2 -2.2 -1.7 1.1
Arm predicted mass (left) 0.3 1.4 3.6 0.9 -1.4 -1.1 -0.0 -1.3 -0.2 0.9 0.9 -0.2 1.8 1.7 -1.9 -1.2 1.3