Best TWAS P=2.09e-11 · Best GWAS P=4.5e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | C8orf58 | 0.25 | 0.09 | enet | 12 | 0.10 | 2.2e-05 | 4.0 | -5.3 | 1.2e-07 | -0.05 | 0.09 | 0.81 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SLC25A37 | 0.11 | 0.09 | lasso | 5 | 0.09 | 7.8e-10 | 6.6 | 6.7 | 2.1e-11 | 0.99 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SLC25A37 | 0.04 | 0.02 | lasso | 2 | 0.03 | 1.1e-04 | 6.6 | 5.5 | 3.4e-08 | 0.89 | 0.00 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC25A37 | 0.13 | 0.00 | blup | 123 | 0.03 | 9.4e-03 | 4.8 | 5.8 | 8.0e-09 | 0.67 | 0.01 | 0.70 | FALSE |