Best TWAS P=2.44e-15 · Best GWAS P=3.08e-15 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | SNX31 | 0.34 | 0.25 | lasso | 11 | 0.29 | 3.6e-35 | -7.9 | -7.0 | 3.5e-12 | 0.95 | 0 | 1.00 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | SNX31 | 0.09 | 0.08 | lasso | 3 | 0.08 | 3.8e-10 | -7.9 | -7.4 | 1.9e-13 | 0.97 | 0 | 1.00 | FALSE |
3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SNX31 | 0.15 | 0.16 | blup | 85 | 0.16 | 1.3e-30 | -7.9 | -7.0 | 3.4e-12 | 0.88 | 0 | 1.00 | FALSE |
4 | The Cancer Genome Atlas | Glioblastoma Multiforme | SNX31 | 0.41 | 0.15 | blup | 84 | 0.18 | 3.0e-06 | -4.2 | -7.6 | 3.7e-14 | 0.77 | 0 | 0.98 | FALSE |
5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SNX31 | 0.20 | 0.20 | lasso | 3 | 0.20 | 7.4e-22 | -7.9 | -7.9 | 2.4e-15 | 0.99 | 0 | 1.00 | TRUE |
6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SNX31 | 0.40 | 0.44 | enet | 15 | 0.45 | 5.3e-56 | -7.9 | -7.8 | 8.2e-15 | 0.97 | 0 | 1.00 | FALSE |
7 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | SNX31 | 0.09 | 0.01 | blup | 83 | 0.01 | 6.5e-02 | -6.5 | -6.5 | 9.8e-11 | 0.70 | 0 | 0.94 | FALSE |
8 | The Cancer Genome Atlas | Lung Adenocarcinoma | SNX31 | 0.05 | 0.03 | lasso | 3 | 0.02 | 3.6e-03 | -7.9 | -7.8 | 4.2e-15 | 0.95 | 0 | 1.00 | FALSE |
9 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SNX31 | 0.32 | 0.20 | enet | 14 | 0.19 | 1.5e-08 | -7.9 | -7.0 | 2.3e-12 | 0.90 | 0 | 1.00 | FALSE |
10 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | SNX31 | 0.28 | 0.23 | lasso | 3 | 0.24 | 7.1e-10 | -6.5 | -7.7 | 1.8e-14 | 0.91 | 0 | 1.00 | FALSE |
11 | The Cancer Genome Atlas | Stomach Adenocarcinoma | SNX31 | 0.20 | 0.18 | lasso | 7 | 0.16 | 2.3e-11 | -7.9 | -7.8 | 8.2e-15 | 0.98 | 0 | 1.00 | FALSE |
12 | The Cancer Genome Atlas | Thyroid Carcinoma | SNX31 | 0.34 | 0.34 | blup | 85 | 0.34 | 5.6e-34 | -7.9 | -7.3 | 2.2e-13 | 0.90 | 0 | 1.00 | FALSE |