[Hub]/) : Traits : Systolic Blood Pressure :

chr8:119,737,284-121,136,001

Best TWAS P=1.09e-17 · Best GWAS P=3.54e-17 conditioned to 0.000359

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NOV 0.06 0.02 enet 8 0.05 1.5e-06 6.7 7.4 1.4e-13 0.61 0.10 0.90 FALSE
2 GTEx Artery Aorta NOV 0.12 0.05 enet 18 0.04 3.7e-03 8.4 8.2 2.9e-16 0.86 0.02 0.91 FALSE
3 GTEx Colon Sigmoid NOV 0.15 0.16 lasso 4 0.15 6.6e-06 8.2 8.2 2.4e-16 0.71 0.05 0.93 FALSE
4 GTEx Esophagus Muscularis NOV 0.11 0.03 enet 19 0.05 3.9e-04 8.2 7.6 2.1e-14 0.61 0.08 0.83 FALSE
5 GTEx Lung NOV 0.06 0.02 enet 23 0.03 2.5e-03 4.5 7.8 8.4e-15 0.76 0.02 0.93 FALSE
6 GTEx Skin Sun Exposed Lower leg NOV 0.11 0.03 lasso 7 0.04 1.4e-04 8.0 7.8 8.4e-15 0.66 0.17 0.81 FALSE
7 NTR Blood NOV 0.02 0.01 bslmm 481 0.01 1.7e-04 8.3 8.6 1.1e-17 0.68 0.05 0.94 TRUE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma NOV 0.03 0.00 blup 42 0.01 5.3e-02 8.0 8.2 2.0e-16 0.67 0.02 0.77 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma NOV 0.31 0.10 blup 42 0.10 1.2e-06 7.9 5.6 1.9e-08 0.54 0.02 0.97 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma NOV 0.11 0.02 enet 15 0.05 2.9e-03 7.9 7.9 3.2e-15 0.59 0.02 0.56 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma NOV 0.04 0.05 blup 42 0.05 8.7e-06 8.3 7.4 1.2e-13 0.71 0.01 0.98 FALSE