Best TWAS P=4.57e-10 · Best GWAS P=1.86e-11 conditioned to 0.00152
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | PLEKHA1 | 0.22 | 0.23 | enet | 17 | 0.19 | 1.1e-13 | -4.7 | 5.5 | 3.3e-08 | 0.48 | 1.00 | 0.00 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | HTRA1 | 0.07 | 0.03 | bslmm | 631 | 0.03 | 2.3e-04 | 6.0 | 6.2 | 4.6e-10 | 0.73 | 0.01 | 0.98 | TRUE |