[Hub]/) : Traits : Systolic Blood Pressure :

chr10:133,048,749-134,466,163

Best TWAS P=5.11e-09 · Best GWAS P=4.38e-10 conditioned to 1.14e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta PPP2R2D 0.21 0.21 lasso 4 0.20 2.1e-11 5.8 -5.8 5.1e-09 -0.03 0.00 1.00 TRUE
2 GTEx Breast Mammary Tissue (Male) PPP2R2D 0.22 0.09 lasso 5 0.13 6.1e-04 5.7 -5.8 7.1e-09 -0.02 0.01 0.90 FALSE
3 GTEx Lung PPP2R2D 0.18 0.06 enet 11 0.10 2.6e-08 5.8 -5.2 2.5e-07 -0.01 0.00 1.00 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic PPP2R2D 0.20 0.08 lasso 6 0.11 2.1e-06 5.9 -5.3 1.4e-07 -0.03 0.00 0.99 FALSE
5 The Cancer Genome Atlas Prostate Adenocarcinoma PPP2R2D 0.05 0.02 blup 18 0.03 8.7e-04 -4.3 -5.4 5.5e-08 0.01 0.01 0.81 FALSE
6 The Cancer Genome Atlas Thyroid Carcinoma PPP2R2D 0.09 0.05 lasso 4 0.06 6.7e-07 -5.1 -5.4 5.4e-08 0.02 0.03 0.97 FALSE