Best TWAS P=4.52e-17 · Best GWAS P=2.92e-24 conditioned to 3.46e-13
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | LOC441601 | 0.21 | 0.12 | lasso | 4 | 0.08 | 4.7e-03 | 5.9 | 5.9 | 4.0e-09 | -0.13 | 0.04 | 0.08 | FALSE |
2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | LOC441601 | 0.30 | 0.16 | blup | 29 | 0.14 | 1.6e-05 | 5.9 | 8.4 | 4.5e-17 | -0.43 | 0.37 | 0.18 | TRUE |