Best TWAS P=1.62e-09 · Best GWAS P=1.98e-12 conditioned to 0.000131
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | C11orf30 | 0.07 | 0.06 | lasso | 6 | 0.06 | 2.1e-07 | 6.5 | -6.0 | 1.6e-09 | -0.92 | 0.01 | 0.99 | TRUE |
2 | GTEx | Cells Transformed fibroblasts | RP11-111M22.3 | 0.14 | 0.07 | lasso | 2 | 0.04 | 2.7e-04 | 5.2 | -5.2 | 2.6e-07 | -0.51 | 0.18 | 0.62 | FALSE |