Best TWAS P=6.23e-11 · Best GWAS P=2.03e-08 conditioned to 0.469
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | RAD52 | 0.25 | 0.16 | enet | 28 | 0.22 | 1.9e-26 | 5.6 | -6.5 | 6.2e-11 | -0.79 | 0.00 | 1.0 | TRUE |
2 | METSIM | Adipose | RAD52 | 0.18 | 0.16 | bslmm | 425 | 0.18 | 5.4e-26 | 5.6 | -5.2 | 1.6e-07 | -0.76 | 0.00 | 1.0 | FALSE |
3 | The Cancer Genome Atlas | Glioblastoma Multiforme | RAD52 | 0.17 | 0.01 | blup | 66 | 0.02 | 9.9e-02 | 5.6 | -5.3 | 1.1e-07 | -0.82 | 0.01 | 0.7 | FALSE |