Best TWAS P=2.62e-10 · Best GWAS P=3.83e-14 conditioned to 3.35e-16
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | APOLD1 | 0.25 | 0.06 | enet | 12 | 0.16 | 5.2e-12 | 3.2 | 5.3 | 1.4e-07 | 0.13 | 0.98 | 0.02 | FALSE |
2 | YFS | Blood | APOLD1 | 0.05 | 0.02 | enet | 17 | 0.05 | 4.5e-16 | 6.3 | 6.3 | 2.6e-10 | 0.09 | 0.56 | 0.44 | TRUE |
3 | YFS | Blood | CDKN1B | 0.03 | 0.03 | enet | 15 | 0.03 | 2.1e-10 | -7.2 | 6.2 | 6.2e-10 | 0.14 | 0.04 | 0.96 | FALSE |