Best TWAS P=2.09e-10 · Best GWAS P=4.47e-12 conditioned to 2.72e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | PPFIBP1 | 0.25 | -0.01 | enet | 28 | 0.02 | 5.1e-02 | 1.7 | 5.5 | 4.8e-08 | -0.02 | 0.06 | 0.19 | FALSE |
| 2 | GTEx | Esophagus Mucosa | TM7SF3 | 0.13 | 0.06 | lasso | 4 | 0.06 | 1.1e-04 | -5.0 | 5.6 | 1.7e-08 | -0.03 | 0.04 | 0.94 | FALSE |
| 3 | GTEx | Esophagus Mucosa | MED21 | 0.29 | 0.30 | lasso | 10 | 0.27 | 2.1e-18 | 6.2 | 6.3 | 2.1e-10 | -0.05 | 0.01 | 0.99 | TRUE |
| 4 | GTEx | Esophagus Mucosa | RP11-421F16.3 | 0.18 | 0.16 | lasso | 6 | 0.14 | 9.8e-10 | -4.0 | 5.5 | 4.7e-08 | -0.02 | 0.61 | 0.39 | FALSE |
| 5 | GTEx | Lung | RP11-421F16.3 | 0.21 | 0.16 | enet | 30 | 0.15 | 8.7e-12 | -4.0 | 5.1 | 3.1e-07 | -0.03 | 1.00 | 0.00 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BHLHE41 | 0.03 | 0.02 | enet | 9 | 0.02 | 2.8e-03 | -4.9 | 5.2 | 2.2e-07 | 0.21 | 0.01 | 0.88 | TRUE |