Best TWAS P=1.51e-09 · Best GWAS P=2.72e-14 conditioned to 3.63e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | EIF4B | 0.21 | 0.07 | enet | 33 | 0.07 | 2.7e-04 | 4.4 | 5.5 | 3.7e-08 | 0.51 | 0.88 | 0.07 | FALSE |
| 2 | GTEx | Artery Aorta | EIF4B | 0.32 | 0.19 | lasso | 3 | 0.23 | 5.4e-13 | 4.4 | 5.5 | 3.1e-08 | 0.51 | 1.00 | 0.00 | FALSE |
| 3 | METSIM | Adipose | EIF4B | 0.10 | 0.10 | lasso | 4 | 0.09 | 3.5e-13 | 5.8 | 5.2 | 1.8e-07 | 0.59 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | EIF4B | 0.25 | 0.10 | blup | 53 | 0.15 | 2.3e-05 | 4.2 | 5.9 | 2.9e-09 | 0.48 | 0.02 | 0.45 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | EIF4B | 0.09 | 0.02 | blup | 53 | 0.05 | 7.8e-04 | 4.3 | 6.0 | 1.5e-09 | 0.44 | 0.19 | 0.20 | TRUE |
| 6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | EIF4B | 0.19 | 0.04 | blup | 53 | 0.09 | 1.8e-04 | 5.7 | 5.7 | 9.6e-09 | 0.47 | 0.05 | 0.29 | FALSE |