Best TWAS P=1.01e-22 · Best GWAS P=9.72e-26 conditioned to 0.000115
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HOXC5 | 0.02 | 0.00 | blup | 51 | 0.01 | 2.4e-02 | -10 | -8.5 | 1.8e-17 | 0.74 | 0.01 | 0.75 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC6 | 0.03 | 0.02 | blup | 50 | 0.03 | 3.9e-04 | -10 | 8.6 | 9.5e-18 | -0.78 | 0.01 | 0.95 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC8 | 0.03 | 0.05 | enet | 5 | 0.04 | 2.4e-05 | -10 | 9.8 | 1.0e-22 | -0.89 | 0.01 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | FLJ12825 | 0.15 | 0.02 | lasso | 5 | 0.06 | 8.9e-03 | -10 | -8.3 | 8.5e-17 | 0.76 | 0.01 | 0.58 | FALSE |