Best TWAS P=1.41e-11 · Best GWAS P=2e-10 conditioned to 0.0615
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | NAA16 | 0.07 | 0.04 | blup | 344 | 0.04 | 1.8e-05 | -6 | 6.8 | 1.4e-11 | -0.76 | 0.01 | 0.99 | TRUE |
2 | GTEx | Brain Cerebellar Hemisphere | MTRF1 | 0.23 | -0.01 | enet | 3 | 0.00 | 2.8e-01 | -6 | 5.2 | 2.2e-07 | -0.77 | 0.03 | 0.36 | FALSE |
3 | GTEx | Brain Cerebellum | MTRF1 | 0.42 | 0.22 | lasso | 14 | 0.28 | 8.5e-09 | -6 | 5.7 | 1.5e-08 | -0.78 | 0.02 | 0.97 | FALSE |
4 | GTEx | Pancreas | NAA16 | 0.21 | 0.18 | lasso | 2 | 0.16 | 3.3e-07 | -6 | 6.3 | 4.0e-10 | -0.94 | 0.01 | 0.99 | FALSE |
5 | NTR | Blood | MTRF1 | 0.03 | 0.02 | bslmm | 343 | 0.02 | 4.0e-07 | -6 | 5.8 | 8.3e-09 | -0.90 | 0.01 | 0.99 | FALSE |
6 | YFS | Blood | MTRF1 | 0.04 | 0.02 | enet | 19 | 0.04 | 7.2e-13 | -6 | 6.0 | 2.6e-09 | -0.69 | 0.01 | 0.99 | FALSE |