Best TWAS P=2.19e-08 · Best GWAS P=2.29e-07 conditioned to 0.00412
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | UGGT2 | 0.20 | 0.20 | enet | 12 | 0.17 | 1.2e-08 | 3.7 | 5.3 | 1.1e-07 | 0.63 | 0.09 | 0.89 | FALSE |
| 2 | GTEx | Esophagus Muscularis | UGGT2 | 0.17 | 0.15 | lasso | 6 | 0.19 | 1.9e-11 | 4.4 | 5.2 | 2.4e-07 | 0.61 | 0.07 | 0.90 | FALSE |
| 3 | GTEx | Small Intestine Terminal Ileum | UGGT2 | 0.20 | 0.00 | enet | 16 | 0.02 | 1.2e-01 | 4.5 | 5.4 | 7.4e-08 | 0.67 | 0.05 | 0.42 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | DNAJC3-AS1 | 0.13 | 0.05 | lasso | 5 | 0.09 | 1.7e-11 | -4.0 | 5.6 | 2.2e-08 | 0.47 | 0.03 | 0.93 | TRUE |