TWAS hub - NAA16

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0670	0.0230	1.3e-04	0.045	0.038	0.032	0.037	0.037	3.4e-06	1.8e-05	7.7e-05	2.2e-05	2.4e-05
2	GTEx	Pancreas	0.2150	0.0610	3.2e-05	0.183	NA	0.132	NA	0.158	3.4e-08	NA	3.4e-06	NA	3.3e-07
3	TCGA	Head and Neck Squamous Cell Carcinoma	0.0466	0.0285	9.0e-04	0.006	0.016	0.007	NA	0.003	6.9e-02	5.7e-03	4.5e-02	NA	1.2e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pulse rate	13.6	22.9	35.0	5.9	4.7	-3.4
Pulse rate, automated reading	7.7	24.7	30.8	5.3	5.6	-3.9
Systolic Blood Pressure	6.2	31.0	45.7	6.8	6.3	-2.9
Father’s age at death	6.1	8.2	11.9	-3.1	-3.5	1.7
Mother’s age at death	5.0	6.2	11.5	-3.4	-2.6	0.6
Alcohol drinker status: Previous	4.5	5.1	7.3	2.7	2.7	-0.9
Commuting to job workplace: Public transport	4.0	4.8	6.4	2.5	2.1	-1.9
Family relationship satisfaction	3.8	4.7	5.9	-2.1	-1.9	2.4
Schizophrenia (2018)	3.7	7.7	14.1	3.8	3.0	-0.4
Systolic blood pressure, automated reading	3.6	10.4	15.5	3.8	3.9	-1.3
Bipolar Disorder or Schizophrenia	2.9	7.1	13.3	3.6	2.8	-0.3
Schizophrenia (2014)	2.9	6.4	12.7	3.6	2.6	0.1
Smoking status: Previous	2.9	4.3	8.7	-3.0	-1.6	1.3
Diastolic blood pressure, automated reading	2.9	9.1	13.4	3.7	3.5	-1.2
Cardiovascular Disease	2.8	9.3	16.3	4.0	3.1	-1.3
Had major operations	2.8	3.3	4.6	2.1	2.2	-0.9
Heart disease (siblings)	2.8	3.4	5.6	1.9	2.4	-1.0
Pulse wave reflection index	2.7	3.3	4.4	-2.0	-1.2	2.1
Ever had hysterectomy (womb removed)	2.5	2.8	6.9	-2.6	-1.2	-0.0
Bilateral oophorectomy (both ovaries removed)	2.5	2.8	3.2	-1.7	-1.6	1.8
Medication: Amlodipine	2.4	3.3	6.0	1.6	2.4	-1.2
Had other major operations	2.3	2.8	3.3	-1.8	-1.5	1.7
Medication: Aspirin	2.3	3.0	3.8	1.9	1.9	1.2
Serious illness, injury or assault to yourself	2.2	2.6	4.8	1.5	2.2	-0.9
Wears glasses or contact lenses	2.1	2.4	4.5	-1.4	-0.8	2.1
Diabetes (self-reported)	2.0	3.1	4.7	1.4	2.2	-1.6
Hypothyroidism (self reported)	1.9	4.4	7.6	2.3	2.8	-0.6
Hearing difficulty/problems: Yes	1.9	2.9	4.5	-2.1	-1.5	1.4
Diabetes (mother)	1.9	2.4	3.5	1.5	1.9	-1.2
Fed-up feelings	1.9	3.4	6.6	1.3	1.4	-2.6
Pain type(s) experienced in last month: Hip pain	1.9	2.3	4.5	-2.1	-1.6	0.1
Noisy workplace	1.8	2.2	3.0	-1.7	-0.9	-1.7
Medication: Allopurinol	1.8	2.4	4.7	-1.5	-0.3	2.2
Crohns Disease (2012)	1.7	2.7	4.4	1.7	2.1	-0.9
Medication: Metformin	1.7	2.4	3.9	0.3	2.0	-1.8
Angina (self-reported)	1.7	2.3	3.4	1.5	1.9	-1.1
Breast Cancer	1.6	3.8	7.6	-1.6	-2.7	1.1
Blood White Count	1.6	12.1	24.2	4.9	3.4	-0.9
Medication: Ramipril	1.6	2.1	3.8	1.5	2.0	0.0
Commuting to job workplace: Car/motor vehicle	1.6	1.8	3.6	-1.4	-1.9	0.0
Hypertension (Self-reported)	1.6	4.5	8.6	2.9	2.1	-0.6
Medication: Aspirin	1.6	2.1	2.5	1.6	1.6	1.1
Hearing aid user	1.6	1.8	2.6	-1.5	-1.6	0.7
Ever depressed for a whole week	1.6	2.0	2.9	-1.7	-1.2	1.3
Vascular/heart problems diagnosed by doctor	1.6	4.3	8.7	-3.0	-2.0	0.3
Neuroticism (Nagel 2018)	1.5	3.6	7.1	1.7	2.7	-0.8
Fasting Glucose	1.5	1.8	2.6	1.6	1.6	-0.5
Birth weight	1.5	3.3	5.9	-2.0	-2.4	-0.2
Chronic bronchitis/emphysema (mother)	1.5	1.7	4.6	-0.7	-0.2	2.2
Mood swings	1.5	2.7	3.9	1.6	2.0	-1.3
Ever taken oral contraceptive pill	1.5	1.7	4.7	0.6	0.0	-2.2
Medication: Blood pressure	1.5	2.8	6.4	2.5	1.4	0.3
Fractured/broken bones in last 5 years	1.5	2.0	4.1	2.0	1.4	-0.1
Angina	1.4	1.8	2.9	1.3	1.7	-0.9
Alcohol intake versus 10 years previously	1.4	2.1	4.4	1.2	2.1	-0.8
Hypothyroidism/myxoedema (self-reported)	1.4	2.8	5.3	1.7	2.3	-0.4
Depressed Affect (Nagel 2018)	1.3	2.6	4.7	1.0	2.2	-1.5
Prostate Cancer	1.3	1.8	3.3	-0.8	-1.1	1.8
HbA1C	1.3	1.5	4.3	0.1	-0.3	2.1
Type 2 Diabetes (T2D) (2018)	1.3	2.5	5.2	1.2	2.3	-0.9
Happiness	1.3	1.6	3.1	-0.7	-1.1	1.8
Knee pain experienced in last month	1.3	2.0	3.0	-1.3	-1.7	1.1
Mouth/teeth dental problems	1.2	1.8	3.0	1.4	0.8	-1.7
Exposure to tobacco smoke at home	1.2	1.4	3.0	1.7	0.7	-0.8
Osteoporosis (self-reported)	1.2	1.5	3.4	-0.5	-0.9	1.8
Average weekly champagne plus white wine intake	1.2	1.6	3.0	1.7	1.4	0.1
Alzheimer’s Disease (in father)	1.1	1.2	2.7	-0.9	-0.5	1.6
Coronary Artery Disease (CAD)	1.1	1.3	2.0	1.4	1.4	0.0
Primary Biliary Cirrhosis	1.1	1.6	1.7	1.3	1.1	-1.3
Lung FEV1/FVC ratio	1.1	5.4	7.1	-2.1	-2.7	2.2
Number of treatments/medications taken	1.1	1.9	3.1	1.5	1.8	-0.5
Pack years adult smoking proportion	1.1	1.7	4.6	2.1	0.6	-0.4
Pain all over the body in last month	1.1	1.2	3.2	0.5	0.5	-1.8
Loud music exposure frequency	1.1	1.2	2.5	-1.6	-0.9	0.5
Worry too long after embarrassment	1.1	1.8	2.5	1.6	1.3	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	2.6	-1.1	-1.6	0.1
Medication: Bendroflumethiazide	1.1	1.7	3.5	1.9	0.8	1.0
Blood Red Count	1.0	10.0	24.6	5.0	2.3	0.2
Neuroticism	1.0	2.4	5.8	0.7	2.4	-0.9
Medication for hormone replacement therapy	1.0	1.1	1.4	-0.8	-1.2	1.1
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.1	0.6	1.0	1.5
Medication: Lansoprazole	1.0	1.2	1.7	1.3	1.2	-0.6
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.3	-0.6	0.3	1.8
Headache pain in last month	1.0	1.6	2.1	-1.4	-0.9	1.5
Gout (self-reported)	1.0	1.4	1.6	-1.3	-1.0	1.2
Illnesses of siblings: Diabetes	1.0	1.2	1.8	1.1	1.3	-0.9
Irritability	1.0	1.7	2.5	1.4	1.6	-0.7
Average weekly spirits intake	0.9	1.2	2.1	0.3	1.1	-1.4
High blood pressure	0.9	2.6	5.9	2.4	1.4	-0.1
Had menopause	0.9	1.1	1.7	-1.1	-1.3	0.6
Financial difficulties in last 2 years	0.9	1.3	2.3	1.2	0.1	1.5
Long-standing illness, disability or infirmity	0.9	1.4	2.4	1.2	1.6	0.4
Cholesterol lowering medication	0.9	1.3	2.3	1.5	1.2	0.2
Pain experienced in last month	0.9	1.5	2.1	1.2	1.4	-1.0
Pack years of smoking	0.9	1.3	3.4	1.9	0.6	-0.4
Worry (Nagel 2018)	0.8	1.6	3.3	1.3	1.8	0.3
Mean Putamen Volume	0.8	0.9	1.6	1.0	1.3	0.3
LDL Cholesterol	0.8	1.3	2.1	0.7	1.5	-1.1
Relative age of first facial hair	0.8	1.5	3.0	-1.7	-1.2	-0.3
Waist circumference	0.8	2.9	5.6	1.6	2.4	0.8
Past tobacco smoking	0.8	1.5	3.3	1.8	0.9	-0.7
Time employed in main current job	0.8	0.9	1.8	-0.4	-1.3	0.9
Illnesses of mother	0.8	1.0	2.2	0.8	1.5	-0.2
Tense / ‘highly strung’	0.8	1.4	3.3	1.8	0.9	0.1
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	2.7	-0.2	-0.7	1.6
Pulse wave peak to peak time	0.8	1.0	2.1	-0.9	-1.5	0.0
Overall health rating	0.8	1.7	4.1	1.0	2.0	-0.2
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	3.1	-0.1	-1.8	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	2.4	-1.6	-0.6	-0.5
Ever had bowel cancer screening	0.8	0.9	1.5	-0.8	0.7	1.2
Mineral and other dietary supplements	0.8	1.0	2.9	1.7	0.4	0.1
Risk taking	0.8	1.2	1.8	0.9	1.0	-1.3
Chronotype (morning person)	0.7	1.5	2.6	-1.0	0.9	-1.6
Impedance of leg (right)	0.7	3.4	4.2	2.0	1.8	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.3	1.1	0.9	0.7
Taking other prescription medications	0.7	1.1	2.8	0.7	1.7	0.2
Age when periods started (menarche)	0.7	1.6	2.3	-0.6	-1.5	1.5
Qualifications: None of the above	0.7	1.5	2.9	0.6	1.7	-1.1
Heart attack	0.7	0.8	1.7	0.5	1.3	-0.7
Medication: Cholesterol lowering	0.7	1.1	1.6	-1.2	1.1	0.7
Depression (self-reported)	0.7	0.8	1.1	-1.0	-1.0	0.5
Prospective memory result	0.7	0.9	1.9	0.2	0.8	-1.4
Lung cancer (father)	0.7	0.8	1.4	-0.3	-1.0	1.2
Pulse wave Arterial Stiffness index	0.7	0.8	1.7	0.9	1.3	0.0
Breastfed as a baby	0.7	0.8	1.2	-1.1	-1.1	-0.0
Leg fat percentage (right)	0.7	2.6	4.2	1.8	2.0	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	2.2	1.5	1.4	0.5
Diabetes diagnosed by doctor	0.7	1.1	2.8	0.2	1.7	-0.7
Alzheimer’s Disease (in mother)	0.6	0.7	1.2	1.1	0.8	-0.7
Ulcerative Colitis (UC)	0.6	1.2	1.8	-1.1	-0.7	1.3
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.4	0.8	1.2	-0.4
Ever used hormone-replacement therapy (HRT)	0.6	0.7	1.7	-0.4	-1.3	0.5
Vitamin and mineral supplements	0.6	0.9	1.8	1.3	-0.4	0.8
Diabetes (father)	0.6	0.7	1.4	1.2	0.8	-0.2
Severe depression (siblings)	0.6	0.7	1.8	1.3	0.4	-0.4
Trunk fat percentage	0.6	2.4	5.0	0.9	1.2	2.2
Current tobacco smoking	0.6	0.9	2.2	1.5	0.4	-0.6
High blood pressure (mother)	0.6	0.9	2.0	-0.3	-0.7	-1.4
Number of live births	0.6	0.8	1.7	-0.3	-0.9	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.6	-0.6	0.5	1.3
Birth weight of first child	0.6	1.0	1.2	-1.1	-0.9	1.0
Medication: Paracetamol	0.6	0.9	2.1	-1.5	-0.7	0.5
Wheeze or whistling in the chest in last year	0.6	1.0	1.5	0.7	1.1	-1.2
Age at last live birth	0.6	0.9	1.9	-0.1	-1.4	0.9
Average weekly red wine intake	0.6	0.9	2.0	-1.4	-0.9	0.3
Friendships satisfaction	0.6	0.7	1.3	-0.6	-1.1	0.7
Qualifications: nursing, teaching	0.6	0.9	1.3	-1.2	-0.9	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.1	0.2	1.0	-1.0
Breast cancer (self-reported)	0.6	0.7	1.1	-0.9	-0.4	1.0
Financial situation satisfaction	0.6	0.7	1.8	0.0	-1.3	0.7
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	1.4	-1.2	-0.5	0.7
Neuroticism (2016)	0.5	0.7	1.0	0.6	1.0	0.9
Heel T-Score	0.5	4.2	4.8	-2.2	-2.2	1.7
Average weekly fortified wine intake	0.5	0.6	1.7	0.1	1.3	0.0
Impedance of leg (left)	0.5	2.4	2.7	1.6	1.6	-1.4
Nervous feelings	0.5	1.0	1.7	1.3	1.1	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.3	0.6	0.9	1.1
Illnesses of siblings	0.5	0.7	1.9	-0.4	-1.4	0.3
Neuroticism score	0.5	1.1	2.3	0.7	1.5	-0.6
Blood clot in the leg (DVT)	0.5	0.6	1.1	-1.0	-0.4	0.8
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.6	0.6	-1.3	-0.7
Body fat percentage	0.5	2.1	3.5	1.1	1.3	1.9
Number of children fathered	0.5	0.5	1.5	-0.3	0.0	1.2
Age at first live birth	0.5	0.9	1.9	-0.9	-1.4	0.1
Neck or shoulder pain in last month	0.5	0.7	1.2	-1.1	-0.5	0.8
Medication: Ibuprofen	0.5	0.6	1.0	1.0	0.9	-0.3
Medication for cholesterol	0.5	0.8	1.6	-1.3	-0.5	-0.8
Leg fat percentage (left)	0.5	1.8	3.0	1.4	1.7	0.8
Age started oral contraceptive pill	0.5	0.7	1.1	-0.8	-1.1	0.5
Basal cell carcinoma (self-reported)	0.5	0.6	0.9	-0.7	-0.7	0.9
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.4	0.3	1.2	-0.6
Bipolar Disorder (2018)	0.4	0.7	1.4	1.2	0.8	-0.0
Depression (Nagel 2018)	0.4	0.6	1.6	0.3	1.2	0.4
Triglycerides	0.4	0.7	1.3	0.1	1.2	-0.9
Sensitivity / hurt feelings	0.4	0.7	1.1	-1.0	-0.7	-0.7
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.0	-0.7	-0.1	1.0
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.2	-1.1	0.1	0.3
Trunk fat mass	0.4	1.9	3.1	0.9	1.4	1.7
Allergy	0.4	0.8	1.3	1.1	1.0	0.4
Arm fat percentage (right)	0.4	1.6	3.6	0.7	0.9	1.9
Hip circumference	0.4	1.9	3.7	1.3	1.9	0.6
Worrier / anxious feelings	0.4	0.8	1.2	0.3	1.0	1.1
Hair/balding pattern: Pattern 3	0.4	0.6	1.5	-1.2	-0.6	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	0.7	0.7	0.9	0.4
Health satisfaction	0.4	0.5	1.1	-0.3	1.1	0.4
Whole body fat mass	0.4	1.5	2.5	0.8	1.2	1.6
Leg fat mass (right)	0.4	1.7	2.8	1.3	1.7	0.8
Alcohol intake frequency.	0.4	0.9	1.6	1.0	1.2	-0.2
Suffer from ‘nerves’	0.4	0.7	1.1	0.4	0.9	1.1
Arm fat percentage (left)	0.4	1.8	4.0	0.7	0.9	2.0
Medication: Gliclazide	0.4	0.5	1.4	0.1	1.2	0.3
Supplements: Fish oil (including cod liver oil)	0.4	0.5	0.7	-0.8	0.4	-0.9
Alcohol drinker status: Never	0.4	0.4	1.2	-1.1	-0.4	0.1
Age at First Birth	0.3	0.4	0.9	-0.5	-0.9	-0.3
Bipolar Disorder (2011)	0.3	0.3	0.6	0.0	0.8	0.5
Body Mass Index (BMI) (2010)	0.3	0.4	0.6	0.7	0.8	-0.0
Lupus	0.3	0.5	0.9	0.0	-1.0	0.7
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.7	0.8	0.5	0.5
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	0.6	0.5	0.6	0.8
Qualifications: CSEs or equivalent	0.3	0.5	0.7	0.8	0.0	0.8
Multivitamins +/- minerals	0.3	0.3	0.6	-0.8	0.5	0.5
Supplements: Glucosamine	0.3	0.3	0.9	-0.3	0.0	-1.0
Sitting height	0.3	2.0	3.5	1.9	1.4	-0.8
Body mass index (BMI)	0.3	1.1	2.5	0.6	0.7	1.6
Hair/balding pattern: Pattern 2	0.3	0.4	0.8	0.2	-0.6	0.9
Forced vital capacity (FVC)	0.3	1.0	2.0	1.4	0.8	-0.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.2	-0.1	1.1	0.0
Qualifications: A levels/AS levels or equivalent	0.3	0.7	1.2	0.1	-1.1	0.9
Mouth/teeth dental problems: Dentures	0.3	0.6	1.5	-1.2	0.4	0.4
Arm fat mass (right)	0.3	1.4	2.9	0.6	1.0	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.9	-1.0	-0.2	0.8
High blood pressure (siblings)	0.3	0.5	0.6	0.4	0.8	-0.8
Comparative body size at age 10	0.3	0.7	1.2	-1.0	-0.0	1.1
Chest pain or discomfort	0.3	0.5	1.2	0.3	1.1	-0.1
Commuting to job workplace: Walk	0.3	0.3	0.6	0.2	0.6	0.8
Back pain experienced in last month	0.3	0.4	0.7	-0.7	0.1	-0.8
Smoking status: Current	0.3	0.5	1.4	1.2	0.1	-0.2
Arm fat mass (left)	0.3	1.2	2.8	0.5	0.8	1.7
Eye problems/disorders: Glaucoma	0.3	0.3	0.8	-0.9	-0.3	0.1
High cholesterol (Self-reported)	0.3	0.6	1.3	-1.2	0.0	0.7
Medication: Paracetamol	0.3	0.4	1.0	-1.0	-0.4	-0.2
Average weekly beer plus cider intake	0.3	0.5	1.1	-0.3	-1.1	-0.4
Commuting to job workplace: Cycle	0.3	0.4	0.8	-0.1	0.7	-0.9
Leg fat mass (left)	0.3	1.2	2.0	1.0	1.4	0.9
Intelligence (Savage-Jansen 2018)	0.2	0.5	0.5	0.7	0.6	-0.7
Schizophrenia vs Biploar Disorder	0.2	0.3	0.8	0.1	-0.9	0.1
Alzheimer’s Disease (including proxy)	0.2	0.3	0.4	0.5	0.6	-0.4
Major Depression (MDD)	0.2	0.2	0.3	-0.2	0.5	0.5
Reaction Time	0.2	0.3	0.9	0.1	0.9	0.1
Blood Eosinophil Count	0.2	1.4	3.6	1.9	-0.2	0.8
Blood Platelet Count	0.2	2.5	3.5	-1.4	-1.9	1.5
BMI	0.2	1.4	2.3	1.2	1.5	0.6
Supplements: Zinc	0.2	0.2	0.6	0.2	-0.8	0.1
Medication: Atenolol	0.2	0.3	0.7	0.8	0.3	-0.3
Medication: Levothyroxine sodium	0.2	0.4	0.7	0.8	0.6	-0.3
Number of incorrect matches in round	0.2	0.3	0.6	0.5	0.8	-0.4
Alcohol usually taken with meals	0.2	0.3	0.7	0.6	0.8	-0.0
Weight	0.2	1.1	1.6	0.8	1.3	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.4	0.7	0.4	0.2
Peak expiratory flow (PEF)	0.2	0.5	1.2	1.1	0.1	-0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.8	0.9	0.0	-0.2
Glaucoma (self-reported)	0.2	0.2	0.6	-0.8	-0.2	-0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.3	0.6	0.4	0.4
Forced vital capacity (FVC), Best measure	0.2	0.8	2.1	1.4	0.5	-0.1
Exposure to tobacco smoke outside home	0.2	0.3	0.6	-0.7	-0.2	0.4
Number of full brothers	0.2	0.3	0.8	-0.2	-0.3	0.9
Shortness of breath walking on level ground	0.2	0.3	0.6	0.3	0.8	-0.4
Eye problems/disorders: None of the above	0.2	0.2	0.6	0.7	0.0	-0.4
Emphysema/chronic bronchitis	0.2	0.3	0.4	-0.7	-0.5	-0.3
Medication: Blood pressure	0.2	0.3	0.9	-0.1	1.0	0.0
Migraine (self-reported)	0.2	0.2	0.5	-0.1	-0.4	-0.7
Medication: Omeprazole	0.2	0.2	0.3	-0.4	-0.4	0.5
Medication: Seretide 50 evohaler	0.2	0.2	0.3	-0.6	-0.6	-0.1
Mean time to correctly identify matches	0.2	0.4	0.5	-0.6	0.6	0.7
Leg pain on walking	0.2	0.3	0.7	0.0	0.9	0.1
Supplements: Vitamin C	0.2	0.2	0.3	-0.5	-0.1	-0.6
Illnesses of father: Heart disease	0.2	0.2	0.4	0.6	-0.4	0.3
Eye problems/disorders: Cataract	0.2	0.2	0.4	0.2	0.6	-0.3
Osteoarthritis (self-reported)	0.2	0.2	0.4	-0.5	-0.7	0.2
Illnesses of father: None of the above (group 1)	0.2	0.2	0.5	-0.4	0.7	-0.4
Number of self-reported non-cancer illnesses	0.2	0.3	0.4	0.6	0.5	0.4
Miserableness	0.2	0.4	1.1	-0.3	1.0	0.4
Medication: Lisinopril	0.2	0.2	0.3	0.4	0.4	-0.6
Medication: Atorvastatin	0.2	0.3	0.4	-0.6	0.6	0.3
Illnesses of father: High blood pressure	0.2	0.2	0.6	0.8	0.3	-0.1
Ever smoked	0.2	0.3	0.5	-0.7	0.0	-0.6
Supplements: Calcium	0.2	0.2	0.5	0.1	-0.2	0.7
Crohns Disease (2017)	0.1	0.3	0.5	-0.5	0.7	-0.3
Irritable Bowel Disease (IBD)	0.1	0.4	0.6	-0.7	0.2	0.7
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.4	0.4	0.6	-0.6
Ovarian Cancer	0.1	0.1	0.2	0.5	0.1	-0.2
HDL Cholesterol	0.1	0.2	0.5	0.1	-0.7	-0.4
Rheumatoid Arthritis	0.1	0.1	0.3	-0.2	-0.3	-0.5
Height	0.1	2.2	4.1	0.2	1.6	-2.0
Waist Hip Ratio (WHR)	0.1	0.7	1.4	0.3	1.2	0.7
Smoking Status	0.1	0.3	0.6	-0.2	-0.8	0.5
Allergy or Eczema	0.1	0.2	0.5	-0.7	-0.5	0.1
Respiratory disease	0.1	0.2	0.3	-0.0	0.4	-0.6
Hair Pigment	0.1	3.8	5.0	-2.2	-1.8	1.8
Tanning	0.1	0.7	1.1	-0.6	-0.8	1.0
Medication: Co-codamol	0.1	0.1	0.1	-0.3	-0.3	0.2
Leg fat-free mass (left)	0.1	0.3	0.9	-0.2	0.2	1.0
Hand grip strength (right)	0.1	0.4	1.0	0.2	1.0	-0.1
Townsend deprivation index at recruitment	0.1	0.2	0.4	0.3	-0.0	0.6
Relative age voice broke	0.1	0.2	0.5	0.2	0.2	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.0	0.0	-0.2	-1.0
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.4	-0.2	-0.3	-0.6
Stomach or abdominal pain in last month	0.1	0.2	0.3	0.2	0.4	-0.6
Chronic bronchitis/emphysema (father)	0.1	0.2	0.4	-0.2	0.7	-0.2
Leg predicted mass (left)	0.1	0.3	0.9	-0.1	0.3	0.9
Hearing difficulty/problems with background noise	0.1	0.2	0.3	-0.6	-0.6	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.5	-0.7	-0.3	-0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.2	-0.4	-0.3	0.2
Medication: Simvastatin	0.1	0.2	0.5	0.3	0.7	0.2
Fluid intelligence score	0.1	0.2	0.3	-0.5	-0.5	0.2
Impedance of arm (right)	0.1	0.3	0.5	0.7	0.3	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.1	0.2	0.3	0.3
Falls in the last year	0.1	0.1	0.2	-0.5	-0.2	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.2	1.1	0.1	-0.1
Length of working week for main job	0.1	0.1	0.1	0.1	-0.4	-0.2
Hair/balding pattern: Pattern 4	0.1	0.1	0.3	-0.3	0.5	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.3	0.6	0.4	0.0
Qualifications: College or University degree	0.1	0.2	0.6	0.8	0.1	0.0
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.3	0.6	0.3	0.3
Heart disease (mother)	0.1	0.1	0.4	0.1	-0.6	0.2
Comparative height size at age 10	0.1	0.6	1.4	-1.2	0.1	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	0.5	-0.4	0.1
Leg fat-free mass (right)	0.1	0.5	1.1	-0.5	-0.1	1.1
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	-0.5	0.2	-0.0
Loneliness, isolation	0.1	0.1	0.2	-0.1	0.5	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.2	0.5	-0.7	-0.0	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.2	-0.2	-0.4	-0.0
Asthma (self-reported)	0.1	0.2	0.4	-0.1	-0.2	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.2	0.4	-0.2	0.4
Leg predicted mass (right)	0.1	0.5	1.3	-0.5	-0.1	1.1
Guilty feelings	0.1	0.2	0.3	-0.6	-0.1	0.4
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.3	-0.5	-0.1	-0.3
Number of operations (self-reported)	0.1	0.2	0.5	0.4	0.7	-0.1
Ever had prostate specific antigen (PSA) test	0.1	0.2	0.4	-0.3	0.2	0.6
Unable to work because of sickness or disability	0.1	0.1	0.1	0.4	0.3	0.4
Impedance of whole body	0.1	0.5	1.0	1.0	0.7	-0.1
Ulcerative Colitis	0.0	0.0	0.1	0.2	0.2	0.2
Lung FVC	0.0	0.1	0.2	0.5	0.3	-0.3
Hand grip strength (left)	0.0	0.1	0.1	-0.3	-0.2	0.2
Maternal smoking around birth	0.0	0.0	0.0	-0.1	-0.0	0.1
Trunk fat-free mass	0.0	0.1	0.2	-0.2	0.3	-0.4
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.3	0.5	-0.4	0.2
Asthma	0.0	0.0	0.1	0.2	0.0	0.3
Impedance of arm (left)	0.0	0.2	0.5	0.4	0.1	0.7
Trunk predicted mass	0.0	0.1	0.2	-0.3	0.3	-0.4
Standing height	0.0	0.4	0.7	0.1	0.8	-0.6
Arm fat-free mass (right)	0.0	0.1	0.3	0.1	0.6	0.1
Medication for pain relief, constipation, heartburn	0.0	0.1	0.2	0.4	-0.2	-0.1
Arm predicted mass (right)	0.0	0.0	0.1	-0.2	0.3	0.1
Number of full sisters	0.0	0.0	0.0	-0.0	-0.1	0.1
Whole body fat-free mass	0.0	0.1	0.1	-0.4	0.1	0.2
Whole body water mass	0.0	0.1	0.1	-0.3	0.2	0.2
Basal metabolic rate	0.0	0.1	0.3	-0.0	0.5	0.4
Arm fat-free mass (left)	0.0	0.1	0.4	0.2	0.6	-0.0
Myopia	0.0	0.0	0.1	0.3	-0.1	0.2
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.1	-0.2	-0.0	-0.3
Arm predicted mass (left)	0.0	0.1	0.2	-0.1	0.5	0.0

Hub : Genes

NAA16

Models

Trait associations