[Hub]/) : Traits : Systolic Blood Pressure :

chr14:35,173,418-36,972,226

Best TWAS P=4.34e-13 · Best GWAS P=4.82e-14 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RALGAPA1 0.10 0.06 bslmm 497 0.08 1.9e-10 -6.1 -5.7 9.3e-09 -0.20 0.95 0.05 TRUE
2 GTEx Adipose Subcutaneous RALGAPA1 0.13 0.16 lasso 5 0.16 5.2e-13 -6.1 -5.8 7.7e-09 -0.17 0.97 0.03 FALSE
3 GTEx Adipose Visceral Omentum RALGAPA1 0.26 0.26 lasso 4 0.28 5.5e-15 -6.1 -6.3 3.0e-10 -0.15 0.96 0.04 FALSE
4 GTEx Adrenal Gland RALGAPA1 0.28 0.20 lasso 6 0.18 5.0e-07 -6.1 -6.1 1.4e-09 -0.17 0.92 0.07 FALSE
5 GTEx Artery Aorta RALGAPA1 0.31 0.38 enet 16 0.36 5.8e-21 -6.1 -6.2 6.0e-10 -0.17 0.97 0.03 FALSE
6 GTEx Artery Coronary RALGAPA1 0.26 0.28 lasso 7 0.31 4.1e-11 -6.2 -5.9 3.5e-09 -0.17 0.92 0.07 FALSE
7 GTEx Artery Tibial RALGAPA1 0.20 0.20 enet 9 0.20 1.5e-15 -6.1 -6.1 1.2e-09 -0.16 0.97 0.03 FALSE
8 GTEx Brain Cerebellum RALGAPA1 0.21 0.17 lasso 4 0.06 6.0e-03 -6.1 -6.1 1.2e-09 -0.16 0.57 0.10 FALSE
9 GTEx Breast Mammary Tissue RALGAPA1 0.30 0.28 lasso 7 0.28 1.7e-14 -6.1 -6.1 7.8e-10 -0.17 0.97 0.03 FALSE
10 GTEx Breast Mammary Tissue (Male) RALGAPA1 0.31 0.23 lasso 6 0.16 1.4e-04 -6.1 -6.4 1.4e-10 -0.15 0.38 0.05 TRUE
11 GTEx Cells EBV-transformed lymphocytes RALGAPA1 0.47 0.45 lasso 15 0.46 6.6e-17 -6.1 -6.3 2.6e-10 -0.17 0.96 0.04 FALSE
12 GTEx Cells Transformed fibroblasts RALGAPA1 0.33 0.44 lasso 4 0.44 1.1e-35 -6.1 -6.1 1.1e-09 -0.16 0.97 0.03 FALSE
13 GTEx Colon Sigmoid RALGAPA1 0.21 0.20 lasso 5 0.21 5.8e-08 -5.9 -6.0 2.1e-09 -0.15 0.95 0.04 FALSE
14 GTEx Colon Transverse RALGAPA1 0.48 0.51 lasso 5 0.52 4.6e-28 -6.1 -6.1 1.0e-09 -0.16 0.96 0.04 FALSE
15 GTEx Esophagus Gastroesophageal Junction RALGAPA1 0.32 0.26 lasso 6 0.25 2.0e-09 -6.1 -6.1 1.2e-09 -0.17 0.96 0.04 FALSE
16 GTEx Esophagus Mucosa RALGAPA1 0.36 0.44 enet 27 0.46 1.1e-33 -6.1 -6.1 9.8e-10 -0.16 0.96 0.04 FALSE
17 GTEx Esophagus Muscularis RALGAPA1 0.18 0.18 enet 9 0.17 1.6e-10 -5.9 -6.2 5.3e-10 -0.16 0.93 0.07 FALSE
18 GTEx Lung RALGAPA1 0.24 0.30 lasso 6 0.31 6.6e-24 -6.1 -6.1 1.0e-09 -0.16 0.96 0.04 FALSE
19 GTEx Nerve Tibial RALGAPA1 0.28 0.40 lasso 3 0.40 4.7e-30 -6.1 -6.0 1.6e-09 -0.15 0.97 0.03 FALSE
20 GTEx Ovary RALGAPA1 0.50 0.32 lasso 4 0.39 1.1e-10 -6.1 -6.1 1.1e-09 -0.16 0.96 0.04 FALSE
21 GTEx Pancreas RALGAPA1 0.34 0.33 lasso 5 0.32 4.3e-14 -6.1 -6.1 1.2e-09 -0.16 0.96 0.04 FALSE
22 GTEx Pituitary RALGAPA1 0.55 0.41 lasso 6 0.49 2.7e-14 -6.1 -6.0 2.3e-09 -0.16 0.96 0.03 FALSE
23 GTEx Prostate RALGAPA1 0.38 0.22 enet 12 0.21 5.3e-06 -6.2 -5.9 4.3e-09 -0.17 0.83 0.05 FALSE
24 GTEx Skin Not Sun Exposed Suprapubic RALGAPA1 0.25 0.22 lasso 4 0.26 1.5e-14 -6.1 -6.0 1.9e-09 -0.17 0.97 0.03 FALSE
25 GTEx Skin Sun Exposed Lower leg RALGAPA1 0.14 0.14 enet 9 0.14 1.9e-11 -6.1 -6.2 6.9e-10 -0.16 0.96 0.04 FALSE
26 GTEx Small Intestine Terminal Ileum RALGAPA1 0.40 0.26 lasso 8 0.32 7.3e-08 -6.5 -6.0 2.2e-09 -0.16 0.87 0.07 FALSE
27 GTEx Stomach RALGAPA1 0.21 0.18 lasso 3 0.14 2.6e-07 -6.1 -5.9 3.9e-09 -0.15 0.96 0.04 FALSE
28 GTEx Testis RALGAPA1 0.33 0.25 enet 20 0.26 7.2e-12 -6.1 -6.2 6.6e-10 -0.18 0.94 0.06 FALSE
29 GTEx Thyroid RALGAPA1 0.30 0.38 lasso 2 0.36 2.7e-28 -6.1 -6.1 1.3e-09 -0.15 0.97 0.03 FALSE
30 GTEx Uterus RALGAPA1 0.42 0.39 lasso 8 0.37 1.4e-08 -6.1 -6.1 1.2e-09 -0.15 0.84 0.04 FALSE
31 GTEx Vagina RALGAPA1 0.54 0.38 enet 16 0.37 1.6e-09 -6.2 -5.7 1.0e-08 -0.14 0.94 0.04 FALSE
32 GTEx Whole Blood RALGAPA1 0.05 0.05 lasso 3 0.04 1.1e-04 -6.1 -6.2 6.4e-10 -0.20 0.69 0.07 FALSE
33 METSIM Adipose RALGAPA1 0.09 0.08 blup 488 0.10 2.1e-14 -6.1 -5.5 3.8e-08 -0.07 0.94 0.06 TRUE
34 NTR Blood NFKBIA 0.26 0.09 lasso 10 0.12 3.4e-36 7.5 7.2 4.3e-13 0.92 0.00 1.00 TRUE
35 YFS Blood NFKBIA 0.24 0.11 enet 33 0.17 3.5e-53 7.5 6.2 6.0e-10 0.72 0.00 1.00 TRUE
36 YFS Blood RALGAPA1 0.11 0.14 lasso 14 0.14 1.7e-44 -6.2 -6.2 7.1e-10 -0.15 0.95 0.05 FALSE
37 The Cancer Genome Atlas Soft Tissue Sarcoma RALGAPA1 0.06 0.04 lasso 2 0.06 2.7e-04 -4.4 -5.5 3.1e-08 -0.15 0.03 0.84 FALSE
38 The Cancer Genome Atlas Thyroid Carcinoma RALGAPA1 0.07 0.00 blup 99 0.03 6.6e-04 -4.1 -5.7 1.2e-08 -0.10 0.04 0.81 FALSE