TWAS hub - NFKBIA

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.256	0.0421	0	0.094	0.101	0.118	0.117	0.119	1.2e-28	9.7e-31	6.6e-36	1.3e-35	3.4e-36
2	YFS	Blood	0.236	0.0418	0	0.106	0.162	0.170	0.163	0.165	1.0e-32	9.8e-51	3.5e-53	4.9e-51	1.2e-51

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood White Count	11.3	83.4	90.9	9.5	8.7
Systolic Blood Pressure	9.1	45.4	52.5	7.2	6.2
Average weekly fortified wine intake	9.1	10.6	12.7	-3.6	-2.9
Age when periods started (menarche)	8.0	19.1	21.0	4.6	4.2
Arm fat-free mass (right)	7.9	40.6	42.7	-6.2	-6.5
Trunk predicted mass	7.7	44.0	44.2	-6.6	-6.7
Trunk fat-free mass	7.6	43.7	43.7	-6.6	-6.6
Arm predicted mass (right)	7.6	39.1	41.8	-6.0	-6.5
Whole body fat-free mass	7.6	43.2	44.2	-6.5	-6.7
Whole body water mass	7.5	42.9	43.4	-6.5	-6.6
Medication: Blood pressure	7.3	13.9	15.5	3.9	3.5
Arm fat-free mass (left)	7.2	36.3	38.0	-5.9	-6.2
Arm predicted mass (left)	7.2	36.4	37.6	-5.9	-6.1
Cardiovascular Disease	7.1	23.3	30.2	5.5	4.0
Leg fat-free mass (right)	7.1	38.1	39.4	-6.1	-6.3
Leg predicted mass (right)	7.1	38.1	39.2	-6.1	-6.3
Basal metabolic rate	7.0	38.9	40.1	-6.1	-6.3
Leg fat-free mass (left)	6.9	36.8	38.3	-5.9	-6.2
Leg predicted mass (left)	6.9	36.8	38.4	-5.9	-6.2
Pulse rate	6.8	11.5	16.2	-2.6	-4.0
Commuting to job workplace: Public transport	6.8	8.1	8.7	2.9	2.8
Systolic blood pressure, automated reading	6.6	19.0	23.2	4.8	3.9
Primary Biliary Cirrhosis	6.3	9.0	12.4	3.5	2.4
Blood clot in the leg (DVT)	6.3	8.2	8.6	-2.8	-2.9
Deep venous thrombosis (DVT) (self-reported)	5.5	7.1	7.8	-2.5	-2.8
Medication: Amlodipine	5.4	7.5	8.0	2.7	2.8
Forced expiratory volume in 1-second (FEV1)	5.2	17.7	20.8	-4.6	-3.8
Forced expiratory volume in 1-second (FEV1), Best measure	5.1	16.4	19.1	-4.4	-3.7
Peak expiratory flow (PEF)	5.0	11.7	12.9	-3.6	-3.2
Comparative height size at age 10	5.0	27.5	28.0	-5.2	-5.3
Hip circumference	4.9	21.1	22.5	-4.4	-4.7
Hypertension (Self-reported)	4.6	12.6	14.1	3.8	3.3
Average weekly spirits intake	4.5	5.6	6.7	-2.6	-2.1
High blood pressure	4.4	12.3	14.1	3.8	3.2
Weight	4.4	21.8	23.4	-4.5	-4.8
Hypothyroidism/myxoedema (self-reported)	4.3	8.4	9.4	2.7	3.1
Relative age voice broke	4.1	6.3	8.8	2.0	3.0
Impedance of leg (left)	3.9	18.8	19.1	4.3	4.4
Forced expiratory volume in 1-second (FEV1), predicted	3.8	7.9	8.2	-2.9	-2.8
Irritable Bowel Disease (IBD)	3.7	8.8	14.2	3.8	1.8
Emphysema/chronic bronchitis	3.7	4.2	6.2	-1.5	-2.5
Impedance of leg (right)	3.6	17.6	17.6	4.2	4.2
Vascular/heart problems diagnosed by doctor	3.6	9.7	11.2	-3.3	-2.9
Hypothyroidism (self reported)	3.5	8.0	8.5	2.7	2.9
Chronic bronchitis/emphysema (father)	3.5	4.1	5.6	2.4	1.6
Myopia	3.5	5.1	5.1	-2.2	-2.3
Illnesses of father: None of the above (group 1)	3.4	4.2	5.3	-1.7	-2.3
Impedance of whole body	3.3	16.6	17.0	4.0	4.1
Lung FEV1/FVC ratio	3.2	16.4	22.6	-4.8	-3.2
Blood Eosinophil Count	3.1	24.3	38.0	6.2	3.2
Standing height	3.1	30.6	31.9	-5.6	-5.4
Risk taking	3.1	4.6	6.5	2.6	1.6
Ulcerative Colitis	3.0	4.4	8.0	2.8	0.9
Height	3.0	58.7	72.4	-8.5	-6.7
Verbal and Numeric Reasoning (VNR)	2.9	6.9	7.5	2.7	2.5
Sitting height	2.9	20.3	21.3	-4.4	-4.6
Waist circumference	2.8	10.3	10.8	-3.1	-3.3
Crohns Disease (2017)	2.6	5.7	8.4	2.9	1.8
Ulcerative Colitis (UC)	2.6	4.9	8.9	3.0	1.0
Commuting to job workplace: Car/motor vehicle	2.6	2.9	3.0	-1.7	-1.7
Forced vital capacity (FVC)	2.5	9.8	11.3	-3.4	-2.9
Impedance of arm (right)	2.5	11.6	12.0	3.4	3.5
Glaucoma (self-reported)	2.5	3.0	3.2	-1.8	-1.6
Schizophrenia (2018)	2.4	5.0	5.5	2.1	2.3
Schizophrenia (2014)	2.4	5.4	7.0	2.0	2.6
Average weekly red wine intake	2.4	3.6	5.2	-1.4	-2.3
Asthma (self-reported)	2.4	4.8	7.2	2.7	1.5
Body Mass Index (BMI) (2010)	2.3	3.2	4.5	-2.1	-1.4
High blood pressure (siblings)	2.3	3.3	4.0	2.0	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.7	3.3	1.8	1.5
Respiratory disease	2.2	4.8	7.9	2.8	1.3
Asthma	2.2	4.4	6.9	2.6	1.4
Pulse wave reflection index	2.2	2.7	4.0	2.0	1.2
Age at first live birth	2.2	3.9	4.4	-1.8	-2.1
Illness, injury, bereavement, stress in last 2 years	2.1	2.6	3.4	1.8	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.4	3.6	-1.9	-1.1
Hayfever, allergic rhinitis or eczema	2.0	4.3	5.9	-1.6	-2.4
Illnesses of siblings	2.0	2.8	3.3	-1.8	-1.5
Medication: Aspirin	2.0	2.7	3.2	-1.8	-1.5
Leg fat mass (left)	2.0	7.9	9.5	-2.5	-3.1
Supplements: Zinc	1.9	2.0	2.9	1.1	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	2.4	-1.5	-1.4
Schizophrenia vs Biploar Disorder	1.8	2.4	3.9	1.0	2.0
Ever had hysterectomy (womb removed)	1.8	2.1	2.8	1.2	1.7
Forced vital capacity (FVC), Best measure	1.8	6.7	8.0	-2.8	-2.3
Mouth/teeth dental problems: Loose teeth	1.8	2.1	3.2	-1.0	-1.8
Age at last live birth	1.8	2.6	2.9	-1.5	-1.7
Arm fat mass (left)	1.8	7.2	8.8	-2.4	-3.0
Wears glasses or contact lenses	1.8	2.1	2.9	-1.1	-1.7
Impedance of arm (left)	1.7	7.8	8.1	2.8	2.8
Leg fat mass (right)	1.7	6.5	8.0	-2.3	-2.8
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.0	2.6	1.2	1.6
Mineral and other dietary supplements	1.7	2.2	2.6	1.4	1.6
Supplements: Calcium	1.7	1.9	2.3	-1.2	-1.5
Allergy or Eczema	1.6	4.3	5.8	-1.7	-2.4
Sensitivity / hurt feelings	1.6	2.8	3.2	-1.8	-1.6
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	2.4	-1.1	-1.5
Father’s age at death	1.6	2.2	2.6	1.6	1.3
Serious illness, injury or assault of a close relative in last 2 years	1.6	1.8	2.1	-1.2	-1.4
Medication: Levothyroxine sodium	1.5	2.6	3.7	1.2	1.9
Arm fat mass (right)	1.5	6.0	7.2	-2.2	-2.7
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.7	2.7	-0.9	-1.6
Heart disease (mother)	1.5	1.9	2.5	1.6	1.1
Osteoarthritis (self-reported)	1.5	1.9	2.1	-1.3	-1.4
Lupus	1.4	2.1	4.2	-0.3	-2.0
Heel T-Score	1.4	11.4	18.1	4.3	2.2
Medication for hormone replacement therapy	1.4	1.6	2.1	-1.4	-1.0
Pulse rate, automated reading	1.4	4.5	6.1	-1.7	-2.5
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	2.8	-1.7	-1.2
Alzheimer’s Disease (including proxy)	1.3	1.9	2.2	1.3	1.5
Relative age of first facial hair	1.3	2.7	4.1	1.1	2.0
Medication: Atenolol	1.3	1.6	1.6	1.2	1.3
Depression (self-reported)	1.3	1.6	1.8	-1.1	-1.3
Mouth/teeth dental problems: Bleeding gums	1.3	1.6	2.3	1.0	1.5
Average weekly champagne plus white wine intake	1.3	1.8	2.1	-1.3	-1.5
Number of treatments/medications taken	1.2	2.2	3.2	1.8	1.1
Allergy	1.2	2.7	4.3	1.0	2.1
Medication: Seretide 50 evohaler	1.2	1.4	2.6	1.6	0.5
Medication for cholesterol	1.2	1.8	2.0	-1.4	-1.3
Ever depressed for a whole week	1.2	1.5	2.7	-0.5	-1.6
Alzheimer’s Disease (in mother)	1.1	1.3	2.1	0.8	1.4
BMI	1.1	6.2	8.7	-1.9	-2.9
Body mass index (BMI)	1.1	4.6	5.5	-1.9	-2.3
Heart attack	1.1	1.4	1.6	-1.3	-1.1
Diabetes (self-reported)	1.1	1.6	2.1	-1.5	-1.1
Commuting to job workplace: Walk	1.1	1.2	1.9	0.7	1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	3.0	-1.7	-1.4
Alcohol drinker status: Never	1.1	1.3	1.5	-1.1	-1.2
Crohns Disease (2012)	1.0	1.7	2.6	1.6	0.8
Ever used hormone-replacement therapy (HRT)	1.0	1.2	1.6	-0.9	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	1.7	-1.3	-1.2
Whole body fat mass	1.0	4.0	5.1	-1.7	-2.3
Medication: Aspirin	1.0	1.4	1.7	-1.3	-1.0
Eye problems/disorders: Cataract	1.0	1.1	2.1	-1.5	-0.4
Guilty feelings	1.0	1.5	2.6	0.6	1.6
Ever had prostate specific antigen (PSA) test	1.0	1.2	2.1	-1.4	-0.5
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	1.4	-1.2	-1.0
Bipolar Disorder (2018)	0.9	1.4	2.0	-1.4	-0.9
Intelligence (Savage-Jansen 2018)	0.9	2.8	3.2	1.8	1.6
Neuroticism (2016)	0.9	1.3	1.6	1.0	1.2
Tanning	0.9	11.2	14.0	3.7	2.9
Nervous feelings	0.9	1.7	1.9	-1.4	-1.3
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	1.7	-0.8	-1.3
Hair/balding pattern: Pattern 3	0.9	1.3	1.9	0.9	1.4
Medication: Lansoprazole	0.9	1.0	1.7	-1.3	-0.6
Headache pain in last month	0.9	1.6	2.3	1.5	0.9
Exposure to tobacco smoke outside home	0.9	1.2	1.5	0.9	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	1.1	-1.1	-1.0
Medication: Omeprazole	0.9	1.0	1.3	-1.1	-0.9
Supplements: Vitamin C	0.9	1.1	2.0	0.4	1.4
Smoking status: Current	0.9	1.4	2.0	-1.4	-0.9
Medication: Atorvastatin	0.9	1.1	1.4	1.2	0.9
Heart attack/myocardial infarction (self-reported)	0.9	1.2	1.2	-1.1	-1.1
High blood pressure (mother)	0.8	1.1	1.3	0.9	1.1
Trunk fat mass	0.8	3.4	4.5	-1.5	-2.1
Qualifications: None of the above	0.8	1.6	2.3	1.0	1.5
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	1.5	1.2	0.6
Birth weight of first child	0.8	1.4	1.4	-1.2	-1.2
Number of self-reported non-cancer illnesses	0.8	1.4	1.9	1.4	0.9
Tinnitus: Yes, now most or all of the time	0.8	1.0	1.8	-1.3	-0.3
High cholesterol (Self-reported)	0.8	1.3	1.8	1.3	1.0
Alcohol drinker status: Previous	0.8	0.9	1.1	1.0	0.9
Fasting Glucose	0.7	0.8	1.3	-1.2	-0.5
HbA1C	0.7	0.8	0.8	-0.9	-0.9
HDL Cholesterol	0.7	1.1	1.7	-0.7	-1.3
Rheumatoid Arthritis	0.7	0.9	1.0	-1.0	-0.9
Waist Hip Ratio (WHR)	0.7	3.2	4.0	1.5	2.0
Hand grip strength (right)	0.7	1.8	2.6	1.6	1.0
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.2	-1.1	-0.6
Pain all over the body in last month	0.7	0.8	1.0	-1.0	-0.7
Fluid intelligence score	0.7	1.5	1.5	1.2	1.2
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.5	-0.2	-1.2
Comparative body size at age 10	0.7	2.0	3.6	-0.6	-1.9
Medication: Blood pressure	0.7	1.2	1.8	-0.8	-1.3
Diabetes diagnosed by doctor	0.7	1.2	2.0	-1.4	-0.6
Friendships satisfaction	0.7	0.8	1.3	-0.5	-1.2
Osteoporosis (self-reported)	0.7	0.8	1.0	-0.8	-1.0
Miserableness	0.7	1.1	1.9	-1.4	-0.6
Supplements: Fish oil (including cod liver oil)	0.7	0.9	1.0	-1.0	-0.9
Medication: Bendroflumethiazide	0.7	1.1	1.7	0.8	1.3
Diabetes (mother)	0.6	0.8	1.5	-1.2	-0.3
Severe depression (siblings)	0.6	0.6	0.8	-0.7	-0.9
Stomach or abdominal pain in last month	0.6	0.8	1.1	0.7	1.0
Had menopause	0.6	0.7	1.0	-0.7	-1.0
Time employed in main current job	0.6	0.7	0.9	-0.8	-0.9
Alcohol intake versus 10 years previously	0.6	0.9	1.1	0.8	1.1
Ovarian Cancer	0.5	0.7	0.8	0.9	0.7
LDL Cholesterol	0.5	0.8	1.3	1.2	0.5
Lung FVC	0.5	2.6	3.9	-2.0	-1.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.1	0.4	1.0
Number of incorrect matches in round	0.5	0.9	1.6	0.4	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.3	-0.5	-1.1
Hearing difficulty/problems with background noise	0.5	0.9	1.0	0.9	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.3	-1.1	-0.5
Exposure to tobacco smoke at home	0.5	0.6	0.8	0.6	0.9
Number of full brothers	0.5	0.7	1.2	0.4	1.1
Eye problems/disorders: None of the above	0.5	0.6	0.9	0.9	0.5
Medication: Ibuprofen	0.5	0.6	1.1	1.0	0.4
Long-standing illness, disability or infirmity	0.5	0.7	1.0	-0.6	-1.0
Illnesses of father: High blood pressure	0.5	0.6	0.6	0.8	0.7
Ever smoked	0.5	0.8	0.9	1.0	0.8
Cholesterol lowering medication	0.5	0.7	0.8	0.8	0.9
Bipolar Disorder or Schizophrenia	0.4	1.1	1.6	0.8	1.2
Alzheimer’s Disease (in father)	0.4	0.5	0.6	0.8	0.6
Coronary Artery Disease (CAD)	0.4	0.4	0.5	-0.6	-0.7
Triglycerides	0.4	0.6	0.8	0.6	0.9
Chronotype (morning person)	0.4	0.9	1.5	0.6	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	1.5	1.2	0.4
Qualifications: CSEs or equivalent	0.4	0.5	1.0	-1.0	-0.0
Multivitamins +/- minerals	0.4	0.5	0.6	-0.8	-0.7
Pulse wave Arterial Stiffness index	0.4	0.5	1.0	-0.1	-1.0
Loud music exposure frequency	0.4	0.4	0.7	-0.3	-0.9
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.0	0.5	1.0
Gout (self-reported)	0.4	0.6	1.1	0.3	1.1
Leg pain on walking	0.4	0.6	0.7	0.6	0.8
Knee pain experienced in last month	0.4	0.7	0.7	0.8	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.5	-0.7	-0.5
Irritability	0.4	0.7	1.1	1.0	0.6
Depressed Affect (Nagel 2018)	0.3	0.7	1.1	0.5	1.1
Reaction Time	0.3	0.5	0.6	-0.8	-0.7
Mean Putamen Volume	0.3	0.3	0.4	0.6	0.6
Blood Platelet Count	0.3	3.5	3.7	1.9	1.8
Type 2 Diabetes (T2D) (2018)	0.3	0.7	1.3	-1.1	-0.1
Frequency of depressed mood in last 2 weeks	0.3	0.5	0.6	-0.8	-0.6
Vitamin and mineral supplements	0.3	0.4	0.5	0.7	0.6
Townsend deprivation index at recruitment	0.3	0.4	0.5	0.7	0.6
Current tobacco smoking	0.3	0.4	0.7	-0.8	-0.3
Taking other prescription medications	0.3	0.4	0.6	0.6	0.8
Hair/balding pattern: Pattern 2	0.3	0.4	0.8	-0.9	-0.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.7	0.3	0.9
Financial difficulties in last 2 years	0.3	0.4	0.6	0.8	0.4
Medication: Ramipril	0.3	0.4	0.8	0.9	0.1
Falls in the last year	0.3	0.4	0.5	-0.7	-0.5
Number of live births	0.3	0.4	0.7	0.2	0.9
Happiness	0.3	0.3	0.3	-0.5	-0.6
Breastfed as a baby	0.3	0.4	0.7	0.8	0.4
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.4	-0.6	-0.6
Pulse wave peak to peak time	0.3	0.4	0.7	-0.1	0.9
Number of full sisters	0.3	0.4	0.6	0.4	0.7
Medication: Gliclazide	0.3	0.3	0.6	0.1	0.8
Medication: Lisinopril	0.3	0.4	0.5	0.7	0.5
Diastolic blood pressure, automated reading	0.3	0.8	1.4	1.2	0.4
Unable to work because of sickness or disability	0.3	0.4	0.4	-0.7	-0.6
Heart disease (siblings)	0.3	0.4	0.4	0.5	0.7
Depression (Nagel 2018)	0.2	0.4	0.4	0.6	0.6
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.5	0.0	-0.7
Blood Red Count	0.2	1.6	3.2	1.8	-0.1
Neuroticism	0.2	0.6	1.0	0.4	1.0
Hearing difficulty/problems: Yes	0.2	0.3	0.4	0.5	0.6
Medication: Metformin	0.2	0.3	0.6	-0.8	0.2
Fed-up feelings	0.2	0.3	0.6	0.1	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.5	0.7	0.4
Serious illness, injury or assault to yourself	0.2	0.2	0.3	-0.3	-0.5
Mouth/teeth dental problems	0.2	0.4	0.6	-0.3	-0.8
Length of working week for main job	0.2	0.2	0.2	-0.4	0.5
Hair/balding pattern: Pattern 4	0.2	0.4	0.5	-0.6	-0.7
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	0.8	0.0	-0.9
Worry too long after embarrassment	0.2	0.3	0.4	-0.6	-0.5
Wheeze or whistling in the chest in last year	0.2	0.4	0.8	0.9	0.1
Chest pain or discomfort	0.2	0.3	0.4	-0.5	-0.7
Family relationship satisfaction	0.2	0.2	0.4	0.2	-0.6
Illnesses of father: Heart disease	0.2	0.3	0.5	-0.0	0.7
Arm fat percentage (left)	0.2	0.6	1.2	-0.4	-1.1
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.4	-0.4	-0.6
Loneliness, isolation	0.2	0.3	0.4	0.5	0.7
Qualifications: nursing, teaching	0.2	0.3	0.5	0.7	0.4
Mother’s age at death	0.2	0.3	0.4	-0.7	-0.4
Eye problems/disorders: Glaucoma	0.2	0.2	0.3	-0.5	-0.4
Fractured/broken bones in last 5 years	0.2	0.3	0.4	0.4	0.6
Commuting to job workplace: Cycle	0.2	0.2	0.4	0.6	-0.0
Pain experienced in last month	0.2	0.4	0.8	-0.9	-0.1
Neuroticism (Nagel 2018)	0.1	0.3	0.7	0.0	0.8
Major Depression (MDD)	0.1	0.1	0.1	-0.1	-0.4
Breast Cancer	0.1	0.3	0.4	0.7	0.3
Age at First Birth	0.1	0.1	0.1	0.4	0.1
Bipolar Disorder (2011)	0.1	0.1	0.1	-0.2	0.2
Smoking Status	0.1	0.1	0.2	-0.2	-0.5
Hand grip strength (left)	0.1	0.4	0.7	0.8	0.2
Diabetes (father)	0.1	0.1	0.3	-0.5	0.0
Maternal smoking around birth	0.1	0.2	0.3	0.5	0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	0.4	0.0
Supplements: Glucosamine	0.1	0.1	0.3	-0.0	-0.5
Had other major operations	0.1	0.1	0.2	0.1	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.5	0.7	-0.2
Medication: Simvastatin	0.1	0.2	0.4	-0.3	0.6
Worrier / anxious feelings	0.1	0.2	0.3	-0.3	-0.5
Noisy workplace	0.1	0.1	0.1	-0.4	0.3
Mouth/teeth dental problems: Dentures	0.1	0.2	0.3	0.5	0.4
Medication: Cholesterol lowering	0.1	0.1	0.2	-0.2	-0.5
Prospective memory result	0.1	0.1	0.3	0.5	-0.1
Tense / ‘highly strung’	0.1	0.2	0.4	-0.6	-0.2
Medication: Paracetamol	0.1	0.2	0.3	0.6	-0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.1	0.4	0.2
Number of children fathered	0.1	0.1	0.1	-0.3	-0.2
Health satisfaction	0.1	0.1	0.2	0.4	0.3
Shortness of breath walking on level ground	0.1	0.1	0.2	0.4	-0.0
Medication for pain relief, constipation, heartburn	0.1	0.1	0.2	0.1	0.4
Neck or shoulder pain in last month	0.1	0.1	0.2	0.2	-0.5
Angina (self-reported)	0.1	0.1	0.1	-0.2	-0.3
Alcohol intake frequency.	0.1	0.2	0.3	-0.6	-0.1
Overall health rating	0.1	0.2	0.4	-0.6	-0.2
Had major operations	0.1	0.1	0.2	0.1	0.4
Illnesses of siblings: Diabetes	0.1	0.1	0.1	0.2	0.4
Smoking status: Previous	0.1	0.2	0.4	0.6	-0.1
Ever had bowel cancer screening	0.1	0.1	0.1	-0.4	-0.2
Medication: Paracetamol	0.1	0.2	0.3	0.5	-0.4
Leg fat percentage (left)	0.1	0.3	0.5	0.0	-0.7
Number of operations (self-reported)	0.1	0.2	0.3	-0.5	-0.1
Average weekly beer plus cider intake	0.1	0.2	0.4	-0.6	0.1
Age started oral contraceptive pill	0.1	0.1	0.2	0.5	-0.0
Basal cell carcinoma (self-reported)	0.1	0.1	0.2	-0.1	-0.4
Pack years of smoking	0.1	0.1	0.1	-0.0	0.4
Worry (Nagel 2018)	0.0	0.1	0.1	-0.0	0.4
Prostate Cancer	0.0	0.0	0.0	-0.2	0.1
Hair Pigment	0.0	0.8	1.6	-0.1	1.3
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.0	0.2	0.2
Angina	0.0	0.0	0.0	-0.1	-0.2
Medication: Co-codamol	0.0	0.0	0.0	0.2	0.2
Pack years adult smoking proportion	0.0	0.1	0.1	0.1	0.3
Trunk fat percentage	0.0	0.1	0.2	0.4	-0.2
Past tobacco smoking	0.0	0.1	0.1	-0.2	0.3
Alcohol usually taken with meals	0.0	0.1	0.1	0.2	-0.3
Neuroticism score	0.0	0.0	0.1	0.1	0.3
Arm fat percentage (right)	0.0	0.2	0.3	-0.0	-0.6
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.0	0.1	-0.0
Lung cancer (father)	0.0	0.1	0.1	-0.3	0.1
Illnesses of mother	0.0	0.0	0.0	0.2	0.0
Birth weight	0.0	0.1	0.1	-0.2	0.3
Body fat percentage	0.0	0.1	0.3	0.5	-0.2
Leg fat percentage (right)	0.0	0.2	0.3	0.2	-0.5
Qualifications: College or University degree	0.0	0.1	0.2	-0.0	0.5
Migraine (self-reported)	0.0	0.0	0.1	-0.3	-0.1
Medication: Allopurinol	0.0	0.1	0.1	-0.3	0.0
Mean time to correctly identify matches	0.0	0.0	0.0	0.0	0.1
Suffer from ‘nerves’	0.0	0.1	0.1	-0.2	-0.2
Mood swings	0.0	0.0	0.1	0.3	0.0
Back pain experienced in last month	0.0	0.0	0.0	0.1	0.1
Breast cancer (self-reported)	0.0	0.1	0.1	-0.3	-0.2
Ever taken oral contraceptive pill	0.0	0.0	0.1	-0.1	0.3
Hearing aid user	0.0	0.0	0.1	-0.0	0.3
Financial situation satisfaction	0.0	0.0	0.0	-0.1	0.0
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.0	-0.1	0.2

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