Best TWAS P=1.16e-09 · Best GWAS P=3.41e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | SMOC1 | 0.14 | 0.12 | enet | 11 | 0.09 | 6.8e-06 | 4.6 | -5.1 | 2.9e-07 | 0.84 | 0.05 | 0.94 | FALSE |
| 2 | GTEx | Artery Coronary | SMOC1 | 0.24 | 0.33 | lasso | 2 | 0.32 | 1.9e-11 | -6.1 | -6.1 | 1.3e-09 | 0.96 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Tibial | SMOC1 | 0.33 | 0.32 | lasso | 10 | 0.33 | 3.0e-26 | -6.1 | -6.1 | 1.2e-09 | 0.97 | 0.00 | 1.00 | TRUE |
| 4 | METSIM | Adipose | PCNX | 0.13 | 0.11 | blup | 440 | 0.11 | 2.5e-16 | -4.1 | 5.6 | 2.7e-08 | -0.05 | 0.19 | 0.74 | TRUE |