[Hub]/) : Traits : Systolic Blood Pressure :

chr14:52,408,380-53,940,700

Best TWAS P=2.45e-12 · Best GWAS P=5.04e-17 conditioned to 4.05e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous STYX 0.07 0.03 enet 15 0.03 8.5e-04 -4.3 -6.2 5.0e-10 0.32 0.84 0.03 FALSE
2 GTEx Cells EBV-transformed lymphocytes STYX 0.24 0.15 lasso 4 0.13 4.9e-05 -5.3 -5.2 2.0e-07 0.29 0.47 0.04 FALSE
3 GTEx Cells Transformed fibroblasts STYX 0.30 0.34 lasso 4 0.36 3.3e-28 -4.5 -5.2 1.5e-07 0.36 1.00 0.00 FALSE
4 GTEx Esophagus Mucosa STYX 0.17 0.09 enet 13 0.04 1.8e-03 -4.4 -5.2 2.1e-07 0.41 0.95 0.01 FALSE
5 GTEx Esophagus Mucosa RP11-841O20.2 0.09 0.01 enet 17 0.02 8.6e-03 -7.5 7.0 2.4e-12 -0.33 0.10 0.31 TRUE
6 GTEx Muscle Skeletal STYX 0.07 0.07 lasso 3 0.06 9.2e-07 -5.3 -5.4 5.2e-08 0.31 0.98 0.00 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma FERMT2 0.02 0.01 blup 63 0.00 5.1e-02 -5.9 -6.8 1.1e-11 0.41 0.08 0.08 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma STYX 0.01 0.01 blup 50 0.01 3.4e-03 4.5 -5.1 2.9e-07 0.35 0.06 0.22 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma STYX 0.06 0.07 lasso 2 0.06 3.0e-04 -5.3 -5.8 7.5e-09 0.34 0.01 0.93 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma STYX 0.06 0.00 blup 50 0.03 5.4e-04 -5.2 -5.8 5.2e-09 0.27 0.01 0.83 TRUE