Best TWAS P=1.25e-10 · Best GWAS P=6.6e-11 conditioned to 2.99e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ATP1B1 | 0.12 | 0.03 | enet | 12 | 0.04 | 2.0e-03 | -6.1 | 6.3 | 2.1e-10 | -0.84 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Brain Cortex | NME7 | 0.37 | 0.08 | lasso | 4 | 0.10 | 8.5e-04 | 5.9 | 5.8 | 6.4e-09 | -0.25 | 0.14 | 0.54 | TRUE |
| 3 | GTEx | Esophagus Mucosa | ATP1B1 | 0.10 | 0.05 | enet | 19 | 0.06 | 5.2e-05 | 6.1 | 6.4 | 1.3e-10 | -0.42 | 0.02 | 0.95 | TRUE |
| 4 | GTEx | Esophagus Muscularis | ATP1B1 | 0.23 | 0.02 | enet | 18 | 0.04 | 2.1e-03 | 6.2 | 5.8 | 9.1e-09 | -0.53 | 0.03 | 0.96 | FALSE |
| 5 | GTEx | Muscle Skeletal | NME7 | 0.13 | 0.07 | enet | 19 | 0.07 | 8.0e-08 | 6.1 | 6.4 | 1.6e-10 | -0.36 | 0.02 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | BLZF1 | 0.28 | 0.00 | enet | 4 | 0.00 | 6.9e-01 | 5.2 | -6.1 | 8.6e-10 | 0.52 | 0.00 | 0.46 | TRUE |