Best TWAS P=1.84e-08 · Best GWAS P=4.38e-12 conditioned to 1.53e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | PDE8A | 0.17 | 0.13 | lasso | 6 | 0.13 | 3.6e-15 | 5.2 | 5.6 | 1.8e-08 | 0.64 | 0.97 | 0.03 | TRUE |
2 | GTEx | Breast Mammary Tissue (Male) | GOLGA6L3 | 0.35 | -0.01 | lasso | 7 | -0.01 | 5.3e-01 | 4.6 | -5.2 | 1.9e-07 | -0.38 | 0.10 | 0.21 | FALSE |