Best TWAS P=8.7e-18 · Best GWAS P=2.93e-23 conditioned to 0.0127
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | ABHD17C | 0.13 | 0.01 | enet | 24 | 0.00 | 1.3e-01 | 4.2 | 6.0 | 2.1e-09 | 0.26 | 0.15 | 0.04 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | FAM108C1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.6e-06 | 8.6 | -8.6 | 8.7e-18 | -0.84 | 0.10 | 0.89 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM108C1 | 0.07 | 0.02 | lasso | 2 | 0.02 | 1.7e-03 | -4.2 | -7.0 | 3.1e-12 | -0.80 | 0.04 | 0.56 | FALSE |