Best TWAS P=1.12e-08 · Best GWAS P=2.41e-09 conditioned to 0.0028
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | CFH | 0.16 | 0.06 | enet | 27 | 0.15 | 5.5e-11 | 3.8 | 5.3 | 1.2e-07 | 0.61 | 0.5 | 0.49 | FALSE |
2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | CFHR4 | 0.22 | 0.08 | lasso | 3 | 0.14 | 3.8e-07 | 5.9 | -5.7 | 1.1e-08 | -0.65 | 0.0 | 1.00 | TRUE |