Best TWAS P=1.22e-08 · Best GWAS P=3.89e-10 conditioned to 1.4e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CAMK1G | 0.09 | 0.03 | lasso | 4 | 0.04 | 4.9e-06 | -4.9 | -5.2 | 1.9e-07 | 0.04 | 0.41 | 0.57 | FALSE |
2 | GTEx | Artery Tibial | DIEXF | 0.12 | 0.07 | lasso | 7 | 0.07 | 6.0e-06 | -5.6 | -5.5 | 3.4e-08 | 0.18 | 0.05 | 0.95 | FALSE |
3 | GTEx | Cells Transformed fibroblasts | DIEXF | 0.19 | 0.14 | lasso | 6 | 0.13 | 3.3e-10 | -5.6 | -5.5 | 3.0e-08 | 0.20 | 0.06 | 0.94 | FALSE |
4 | METSIM | Adipose | TRAF3IP3 | 0.04 | 0.01 | blup | 491 | 0.01 | 6.3e-03 | -3.3 | 5.7 | 1.2e-08 | -0.40 | 0.21 | 0.18 | TRUE |