Best TWAS P=1.91e-09 · Best GWAS P=5.07e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP11-1055B8.4 | 0.33 | 0.12 | lasso | 7 | 0.14 | 3.2e-11 | -6.2 | 5.5 | 3.0e-08 | -0.89 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Brain Cerebellum | RP11-1055B8.4 | 0.25 | 0.27 | lasso | 2 | 0.27 | 1.3e-08 | -6.2 | 6.0 | 1.9e-09 | -0.99 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Lung | AZI1 | 0.11 | 0.01 | lasso | 4 | 0.01 | 5.9e-02 | 5.1 | 5.3 | 9.3e-08 | 0.01 | 0.33 | 0.22 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | RP11-1055B8.4 | 0.21 | 0.10 | lasso | 3 | 0.10 | 7.4e-09 | -6.2 | 5.7 | 1.6e-08 | -0.96 | 0.00 | 1.00 | FALSE |