[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr17:75,977,988-77,462,467

Best TWAS P=7.07e-15 · Best GWAS P=5.89e-14 conditioned to 0.096

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex USP36 0.14 0.13 lasso 3 0.13 1.7e-15 6.9 -7.0 2.8e-12 -0.96 0.03 0.97 FALSE
2 GTEx Adipose Subcutaneous CYTH1 0.13 0.03 lasso 5 0.04 5.7e-04 7.2 6.8 8.6e-12 0.83 0.06 0.73 FALSE
3 GTEx Brain Cerebellum USP36 0.31 0.20 enet 18 0.13 9.7e-05 6.3 -6.0 1.6e-09 -0.79 0.08 0.79 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia USP36 0.36 0.23 lasso 5 0.20 4.8e-06 7.4 -7.2 7.1e-13 -0.98 0.02 0.97 FALSE
5 GTEx Esophagus Mucosa USP36 0.11 0.04 enet 13 0.06 1.1e-04 7.3 -7.7 1.6e-14 -0.88 0.03 0.97 FALSE
6 GTEx Esophagus Muscularis USP36 0.18 0.16 lasso 3 0.08 2.5e-05 6.9 5.8 5.3e-09 0.87 0.04 0.96 FALSE
7 GTEx Muscle Skeletal CYTH1 0.13 0.12 lasso 3 0.13 2.5e-12 7.2 7.1 1.5e-12 0.92 0.05 0.95 FALSE
8 GTEx Testis USP36 0.32 0.24 lasso 6 0.26 6.2e-12 5.6 -6.6 3.2e-11 -0.93 0.06 0.94 FALSE
9 GTEx Thyroid USP36 0.21 0.15 enet 45 0.16 1.6e-12 6.7 -5.3 1.2e-07 -0.86 0.28 0.72 FALSE
10 GTEx Thyroid CYTH1 0.24 0.07 lasso 11 0.06 3.4e-05 7.3 7.8 7.1e-15 0.85 0.03 0.97 TRUE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma TIMP2 0.06 0.01 blup 76 0.02 3.4e-03 3.7 -5.8 8.3e-09 -0.66 0.03 0.23 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma USP36 0.04 0.00 blup 57 0.01 2.9e-02 7.3 -6.8 1.5e-11 -0.83 0.01 0.51 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors USP36 0.10 0.02 lasso 4 0.05 6.6e-03 7.1 -5.8 6.7e-09 -0.81 0.01 0.86 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma CYTH1 0.11 0.09 lasso 4 0.08 2.4e-08 -5.9 5.6 2.3e-08 0.59 0.91 0.09 FALSE